PRJNA207719: Tissue specific transcriptome profiling


Results for foxi1+foxi2+foxi3a+foxi3b

Z-value: 1.53

Motif logo

Transcription factors associated with foxi1+foxi2+foxi3a+foxi3b

Gene Symbol Gene ID Gene Info
ENSDARG00000009550 forkhead box I3b
ENSDARG00000055926 forkhead box I3a
ENSDARG00000069715 forkhead box I2
ENSDARG00000104566 forkhead box i1
ENSDARG00000112022 forkhead box I3b
ENSDARG00000112303 forkhead box I3b
ENSDARG00000116791 forkhead box I2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot

Activity profile of foxi1+foxi2+foxi3a+foxi3b motif

Sorted Z-values of foxi1+foxi2+foxi3a+foxi3b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_37837245 2.93 ENSDART00000171617
chr8_-_14049404 1.77 ENSDART00000093117
ATPase plasma membrane Ca2+ transporting 3a
chr5_+_36768674 1.56 ENSDART00000146854
MAP/microtubule affinity-regulating kinase 4a
chr14_-_32016615 1.37 ENSDART00000105761
zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila)
chr4_+_8797197 1.28 ENSDART00000158671
sulfotransferase family 4A, member 1
chr12_+_5081759 1.26 ENSDART00000164178
proline-rich transmembrane protein 2
chr6_-_35446110 1.23 ENSDART00000058773
regulator of G protein signaling 16
chr10_-_24343507 1.21 ENSDART00000002974
phosphatidylinositol transfer protein, alpha b
chr1_-_30039331 1.20 ENSDART00000086935
chr16_-_17207754 1.15 ENSDART00000063804
chr10_+_17850934 1.15 ENSDART00000113666
PHD finger protein 24
chr20_+_30445971 1.13 ENSDART00000153150
myelin transcription factor 1-like, a
chr10_-_43404027 1.06 ENSDART00000086227
EGF-like repeats and discoidin I-like domains 3b
chr13_+_27316934 1.03 ENSDART00000164533
eukaryotic translation elongation factor 1 alpha 1a
chr15_-_18432673 1.00 ENSDART00000146853
neural cell adhesion molecule 1b
chr14_-_2352384 0.99 ENSDART00000170666
chr7_+_52766211 0.98 ENSDART00000186191
diphosphoinositol pentakisphosphate kinase 1a
chr24_-_17444067 0.94 ENSDART00000155843
contactin associated protein like 2a
chr16_-_29334672 0.94 ENSDART00000162835
chr19_-_27261102 0.93 ENSDART00000143919
gamma-aminobutyric acid (GABA) B receptor, 1b
chr2_+_3595333 0.93 ENSDART00000041052
complement component 1, q subcomponent-like 3b
chr10_+_1638876 0.93 ENSDART00000184484
small G protein signaling modulator 1b
chr6_-_10780698 0.91 ENSDART00000151714
G protein-coupled receptor 155b
chr19_-_44091405 0.91 ENSDART00000132800
RAD21 cohesin complex component b
chr2_+_5563077 0.88 ENSDART00000111220
Mab-21 domain containing 2
chr6_-_39167732 0.87 ENSDART00000153626
apolipoprotein F
chr21_+_31434251 0.84 ENSDART00000040740
chr5_-_33215261 0.82 ENSDART00000097935
chr19_+_1510971 0.81 ENSDART00000157721
solute carrier family 45 member 4
chr2_-_37043540 0.81 ENSDART00000131834
guanine nucleotide binding protein (G protein), gamma 7
chr14_-_32403554 0.79 ENSDART00000172873
fibroblast growth factor 13a
chr22_+_31821815 0.79 ENSDART00000159825
dedicator of cytokinesis 3
chr14_-_18671334 0.78 ENSDART00000182381
SLIT and NTRK-like family, member 4
chr7_-_52842605 0.78 ENSDART00000083002
microtubule-associated protein 1Aa
chr19_+_2275019 0.78 ENSDART00000136138
integrin, beta 8
chr1_+_6817292 0.77 ENSDART00000145822
erb-b2 receptor tyrosine kinase 4a
chr5_-_23362602 0.76 ENSDART00000137120
glutamate receptor, ionotropic, AMPA 3a
chr12_+_13405445 0.76 ENSDART00000089042
potassium voltage-gated channel, subfamily H (eag-related), member 4b
chr12_+_13404784 0.76 ENSDART00000167977
potassium voltage-gated channel, subfamily H (eag-related), member 4b
chr19_-_8880688 0.75 ENSDART00000039629
cugbp, Elav-like family member 3a
chr17_+_15534815 0.75 ENSDART00000159426
myristoylated alanine-rich protein kinase C substrate b
chr2_-_37043905 0.75 ENSDART00000056514
guanine nucleotide binding protein (G protein), gamma 7
chr24_-_23942722 0.73 ENSDART00000080810
aristaless related homeobox a
chr20_-_4883673 0.72 ENSDART00000145540
zinc finger, DHHC-type containing 14
chr7_-_52334429 0.72 ENSDART00000187372

chr5_-_61942482 0.70 ENSDART00000097338
N-ethylmaleimide-sensitive factor attachment protein, alpha a
chr2_-_31798717 0.69 ENSDART00000170880
reticulophagy regulator 1
chr14_-_2348917 0.69 ENSDART00000159004
chr25_-_11088839 0.69 ENSDART00000154748
synaptic vesicle glycoprotein 2Bb
chr6_+_39222598 0.68 ENSDART00000154991
beta-1,4-N-acetyl-galactosaminyl transferase 1b
chr5_+_49744713 0.67 ENSDART00000133384
nuclear receptor subfamily 2, group F, member 1a
chr18_-_26126258 0.66 ENSDART00000145875
ankyrin repeat domain 34C
chr6_-_12270226 0.66 ENSDART00000180473
plakophilin 4
chr21_-_42202792 0.65 ENSDART00000124708
gamma-aminobutyric acid (GABA) A receptor, alpha 6b
chr20_-_8304271 0.63 ENSDART00000179057
Dab, reelin signal transducer, homolog 1a (Drosophila)
chr19_-_9503473 0.63 ENSDART00000091615
intermediate filament family orphan 1a
chr2_-_12243213 0.62 ENSDART00000113081
G protein-coupled receptor 158b
chr6_-_6448519 0.62 ENSDART00000180157
chr10_+_21730585 0.61 ENSDART00000188576
protocadherin 1 gamma 22
chr10_+_1849874 0.61 ENSDART00000158897
adenomatous polyposis coli
chr4_-_6567355 0.60 ENSDART00000134820
forkhead box P2
chr7_-_49801183 0.60 ENSDART00000052083
four jointed box 1
chr14_-_21219659 0.60 ENSDART00000089867
protein phosphatase 2, regulatory subunit B, gamma b
chr7_-_49800755 0.60 ENSDART00000180072
four jointed box 1
chr11_-_17713987 0.59 ENSDART00000090401
family with sequence similarity 19 (chemokine (C-C motif)-like), member A4b
chr21_-_21148623 0.58 ENSDART00000184364
ankyrin 1, erythrocytic b
chr16_+_22654481 0.58 ENSDART00000179762
cholinergic receptor, nicotinic, beta 2b
chr9_-_33785093 0.56 ENSDART00000140779
FUN14 domain containing 1
chr3_+_22578369 0.55 ENSDART00000187695
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2a
chr11_+_30817943 0.55 ENSDART00000150130
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, b
chr14_-_21218891 0.54 ENSDART00000158294
protein phosphatase 2, regulatory subunit B, gamma b
chr15_+_23657051 0.54 ENSDART00000078336
kinesin light chain 3
chr20_-_26042070 0.54 ENSDART00000140255
chr13_-_32626247 0.53 ENSDART00000100663
WD repeat domain 35
chr7_+_7511914 0.53 ENSDART00000172848
chloride channel 3
chr2_+_11685742 0.52 ENSDART00000138562
growth regulation by estrogen in breast cancer-like
chr20_-_31252809 0.52 ENSDART00000137236
hippocalcin-like 1
chr14_+_28438947 0.52 ENSDART00000006489
acyl-CoA synthetase long chain family member 4a
chr1_+_2190714 0.51 ENSDART00000132126
muscleblind-like splicing regulator 2
chr11_+_34523132 0.50 ENSDART00000192257
zinc finger, matrin-type 3
chr8_+_13368150 0.50 ENSDART00000114699
solute carrier family 5 (sodium/iodide cotransporter), member 5
chr14_+_34966598 0.50 ENSDART00000004550
ring finger protein 145a
chr16_+_18535618 0.50 ENSDART00000021596
retinoid x receptor, beta b
chr5_+_42912966 0.49 ENSDART00000039973
RUN and FYVE domain containing 3
chr10_-_11840353 0.49 ENSDART00000127581
tripartite motif containing 23
chr1_-_50611031 0.49 ENSDART00000148285
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr16_+_28932038 0.48 ENSDART00000149480
natriuretic peptide receptor 1b
chr23_-_42810664 0.48 ENSDART00000102328
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a
chr11_+_21586335 0.46 ENSDART00000091182
chr3_-_43356082 0.46 ENSDART00000171213
UNC homeobox
chr10_+_34315719 0.46 ENSDART00000135303
StAR-related lipid transfer (START) domain containing 13a
chr5_-_48070779 0.46 ENSDART00000078401
transmembrane protein 161B
chr5_-_37935607 0.45 ENSDART00000141233
sodium channel, voltage-gated, type IV, beta b
chr22_-_21755524 0.43 ENSDART00000149635
transducin like enhancer of split 2b
chr15_+_3674765 0.43 ENSDART00000081802
NIMA related kinase 3
chr15_+_42431198 0.42 ENSDART00000189951
T cell lymphoma invasion and metastasis 1b
chr12_+_26467847 0.41 ENSDART00000022495
nudE neurodevelopment protein 1-like 1a
chr6_+_46431848 0.40 ENSDART00000181056
staufen double-stranded RNA binding protein 1
chr1_+_45839927 0.40 ENSDART00000148086
mitogen-activated protein kinase kinase 7
chr11_-_21586157 0.40 ENSDART00000190095
SLIT-ROBO Rho GTPase activating protein 2
chr15_+_25681044 0.39 ENSDART00000077853
hypermethylated in cancer 1
chr13_+_2442841 0.39 ENSDART00000114456
ARFGEF family member 3
chr4_-_12978925 0.39 ENSDART00000013839
transmembrane BAX inhibitor motif containing 4
chr7_+_49800849 0.39 ENSDART00000164838
chr20_-_45062514 0.39 ENSDART00000183529
kelch-like family member 29
chr15_-_20024205 0.38 ENSDART00000161379
autism susceptibility candidate 2b
chr16_+_5612547 0.38 ENSDART00000140226
chr15_+_28940352 0.38 ENSDART00000154085
gastric inhibitory polypeptide receptor
chr10_+_21584195 0.37 ENSDART00000100599
protocadherin 1 alpha 3
chr15_-_20933574 0.37 ENSDART00000152648
ubiquitin specific peptidase 2a
chr22_-_14367966 0.37 ENSDART00000188796
low density lipoprotein receptor-related protein 1Ba
chr25_-_14087377 0.36 ENSDART00000124140
chr18_-_20560007 0.35 ENSDART00000141367
chr7_+_24023653 0.34 ENSDART00000141165
TERF1 (TRF1)-interacting nuclear factor 2
chr18_-_15532016 0.33 ENSDART00000165279
PTPRF interacting protein, binding protein 1b (liprin beta 1)
chr2_-_16216568 0.33 ENSDART00000173758
Rho guanine nucleotide exchange factor (GEF) 4
chr1_+_33647682 0.33 ENSDART00000114384
zinc finger protein 654
chr11_+_33628104 0.31 ENSDART00000165318
thrombospondin, type I, domain containing 7Bb
chr19_-_27462720 0.30 ENSDART00000135901
chr24_-_18659147 0.30 ENSDART00000166039
chr24_-_9002038 0.30 ENSDART00000066783
metallophosphoesterase 1
chr4_-_14926637 0.30 ENSDART00000110199
PR domain containing 4
chr2_+_31437547 0.30 ENSDART00000141170
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
chr4_-_6809323 0.29 ENSDART00000099467
interferon-related developmental regulator 1
chr8_-_7567815 0.28 ENSDART00000132536
host cell factor C1b
chr12_-_31422433 0.28 ENSDART00000186075
vesicle transport through interaction with t-SNAREs 1A
chr14_-_33177935 0.28 ENSDART00000180583
discs, large homolog 3 (Drosophila)
chr12_-_35505610 0.27 ENSDART00000105518
calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1
chr10_-_31563049 0.27 ENSDART00000023575
roundabout, axon guidance receptor, homolog 3 (Drosophila)
chr1_-_46862190 0.27 ENSDART00000145167
1-acylglycerol-3-phosphate O-acyltransferase 3
chr18_+_37015185 0.27 ENSDART00000191305
signal-induced proliferation-associated 1 like 3
chr12_-_13966184 0.26 ENSDART00000066368
kelch-like family member 11
chr9_-_7238839 0.26 ENSDART00000142726
cellular repressor of E1A-stimulated genes 2
chr6_-_14038804 0.26 ENSDART00000184606
ets variant 5b
chr10_-_43568239 0.26 ENSDART00000131731
myocyte enhancer factor 2ca
chr14_+_35023923 0.25 ENSDART00000172171
early B cell factor 3a
chr23_+_17220986 0.24 ENSDART00000054761
nucleolar protein 4-like b
chr18_+_27077853 0.24 ENSDART00000125326
protein phosphatase 1, regulatory subunit 15B
chr18_+_12147971 0.24 ENSDART00000162067
FYVE, RhoGEF and PH domain containing 4a
chr4_-_9609634 0.24 ENSDART00000067188
DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae)
chr23_-_27822920 0.23 ENSDART00000023094
activin A receptor type 1Ba
chr4_-_74892355 0.23 ENSDART00000188725
PHD finger protein 21B
chr18_-_5111449 0.23 ENSDART00000046902
programmed cell death 10a
chr19_+_20724347 0.23 ENSDART00000090757
K(lysine) acetyltransferase 2B
chr21_-_33995710 0.23 ENSDART00000100508
early B cell factor 1b
chr1_+_51191049 0.22 ENSDART00000132244
BTB (POZ) domain containing 3a
chr9_-_38399432 0.22 ENSDART00000148268
zinc finger protein 142
chr15_-_33807758 0.22 ENSDART00000158445
PDS5 cohesin associated factor B
chr20_-_45709990 0.22 ENSDART00000027482
glycerophosphocholine phosphodiesterase 1
chr5_+_53009083 0.21 ENSDART00000157836
histidine triad nucleotide binding protein 2
chr16_+_38820486 0.21 ENSDART00000131866
thyrotropin-releasing hormone receptor a
chr18_-_21725638 0.21 ENSDART00000089853
FANCD2/FANCI-associated nuclease 1
chr12_+_18544159 0.20 ENSDART00000162900
MTOR associated protein, LST8 homolog (S. cerevisiae)
chr16_-_13622794 0.20 ENSDART00000146953
chr23_-_26652273 0.20 ENSDART00000112124
heparan sulfate proteoglycan 2
chr15_+_26941063 0.20 ENSDART00000149957
breast carcinoma amplified sequence 3
chr6_-_40922971 0.19 ENSDART00000155363
SFI1 centrin binding protein
chr18_-_25855263 0.19 ENSDART00000042074
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Ba
chr23_-_27857051 0.19 ENSDART00000043462
activin A receptor like type 1
chr13_-_30645965 0.19 ENSDART00000109307
zinc finger, CCHC domain containing 24
chr3_-_2623176 0.18 ENSDART00000179792
chr22_+_30112390 0.18 ENSDART00000191715
adducin 3 (gamma) a
chr7_+_42206847 0.18 ENSDART00000149250
phosphorylase kinase, beta
chr14_+_7932973 0.18 ENSDART00000109941
CXXC finger protein 5b
chr8_+_26293673 0.18 ENSDART00000144977
monoglyceride lipase
chr18_-_7137153 0.18 ENSDART00000019571
CD9 molecule a
chr23_-_33680265 0.18 ENSDART00000138416
transcription factor CP2
chr11_+_25693395 0.17 ENSDART00000110224
MON1 secretory trafficking family member Bb
chr10_+_26972755 0.17 ENSDART00000042162
transmembrane 7 superfamily member 2
chr12_-_14211067 0.17 ENSDART00000077903
AVL9 homolog (S. cerevisiase)
chr14_-_6943934 0.17 ENSDART00000126279
CDC-like kinase 4a
chr15_+_26940569 0.16 ENSDART00000189636
breast carcinoma amplified sequence 3
chr17_-_38778826 0.16 ENSDART00000168182
D-glutamate cyclase
chr17_-_50220228 0.16 ENSDART00000058707
Jun dimerization protein 2a
chr5_-_56924747 0.16 ENSDART00000014028
protein phosphatase, Mg2+/Mn2+ dependent, 1Db
chr17_-_14966384 0.16 ENSDART00000105064
thioredoxin domain containing 16
chr20_+_42565049 0.16 ENSDART00000061101
insulin-like growth factor 2 receptor
chr1_-_22757145 0.16 ENSDART00000134719
prominin 1 b
chr16_-_24561354 0.15 ENSDART00000193278
chr4_+_6833583 0.15 ENSDART00000165179
dedicator of cytokinesis 4b
chr23_-_27152866 0.15 ENSDART00000141305
chr9_-_38398789 0.15 ENSDART00000188384
zinc finger protein 142
chr7_+_13830052 0.15 ENSDART00000191360
abhydrolase domain containing 2a
chr4_-_18436899 0.14 ENSDART00000141671
suppressor of cytokine signaling 2
chr19_-_12965020 0.14 ENSDART00000128975
solute carrier family 25 (mitochondrial folate carrier), member 32a
chr23_+_21479958 0.14 ENSDART00000188302
chr3_+_53116172 0.14 ENSDART00000115117
bromodomain containing 4
chr9_-_27719998 0.14 ENSDART00000161068
general transcription factor IIE, polypeptide 1, alpha
chr2_+_47471943 0.14 ENSDART00000141974
acyl-CoA synthetase long chain family member 3b
chr7_+_29080684 0.14 ENSDART00000173709
ACD, shelterin complex subunit and telomerase recruitment factor
chr17_+_37511092 0.14 ENSDART00000187935
metastasis associated 1
chr7_+_52712807 0.14 ENSDART00000174095
zinc finger protein 280D
chr2_+_47471647 0.13 ENSDART00000184199
acyl-CoA synthetase long chain family member 3b
chr11_-_24523161 0.13 ENSDART00000191936
pleckstrin homology domain containing, family G (with RhoGef domain) member 5a
chr21_-_33995213 0.13 ENSDART00000140184
chr19_-_45650994 0.13 ENSDART00000163504
trichorhinophalangeal syndrome I
chr9_+_27720428 0.12 ENSDART00000112415
leucine carboxyl methyltransferase 2
chr5_-_2676783 0.12 ENSDART00000159661

chr11_+_26609110 0.12 ENSDART00000042322
microtubule-associated protein 1 light chain 3 alpha
chr11_-_36350421 0.12 ENSDART00000141477
proteasome subunit alpha 5

Network of associatons between targets according to the STRING database.

First level regulatory network of foxi1+foxi2+foxi3a+foxi3b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0035095 behavioral response to nicotine(GO:0035095)
0.2 0.9 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.2 0.7 GO:0003322 pancreatic A cell development(GO:0003322)
0.2 0.7 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.2 0.6 GO:1905067 endodermal digestive tract morphogenesis(GO:0061031) Wnt signaling pathway involved in somitogenesis(GO:0090244) negative regulation of canonical Wnt signaling pathway involved in heart development(GO:1905067)
0.1 0.6 GO:0023041 neuronal signal transduction(GO:0023041)
0.1 1.1 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 0.9 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.1 0.3 GO:0036076 ligamentous ossification(GO:0036076)
0.1 0.5 GO:1900744 regulation of p38MAPK cascade(GO:1900744)
0.1 0.4 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.1 0.6 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.1 0.2 GO:1903358 regulation of Golgi organization(GO:1903358)
0.1 0.2 GO:0090069 regulation of ribosome biogenesis(GO:0090069)
0.1 1.0 GO:0006020 inositol metabolic process(GO:0006020)
0.1 0.7 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011)
0.1 0.7 GO:0050714 positive regulation of protein secretion(GO:0050714)
0.1 0.7 GO:0061709 reticulophagy(GO:0061709)
0.1 0.4 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.1 1.6 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 0.8 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.7 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.5 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.1 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.0 0.1 GO:0001120 DNA-templated transcriptional open complex formation(GO:0001112) transcriptional open complex formation at RNA polymerase II promoter(GO:0001113) protein-DNA complex remodeling(GO:0001120)
0.0 0.2 GO:0034405 response to fluid shear stress(GO:0034405)
0.0 1.3 GO:0051923 sulfation(GO:0051923)
0.0 0.1 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.0 0.1 GO:0031591 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.0 0.2 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0 0.6 GO:0045471 response to ethanol(GO:0045471)
0.0 0.7 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.9 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.0 0.3 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.0 0.3 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.3 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.5 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.0 3.7 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 0.7 GO:0051932 synaptic transmission, GABAergic(GO:0051932)
0.0 0.3 GO:1904356 regulation of telomere maintenance via telomere lengthening(GO:1904356)
0.0 0.6 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 1.4 GO:0009948 anterior/posterior axis specification(GO:0009948)
0.0 0.1 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.2 GO:0001709 cell fate determination(GO:0001709)
0.0 0.3 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.7 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.4 GO:0043507 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.1 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.1 GO:2000055 positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000055)
0.0 0.2 GO:0035306 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0 0.7 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.3 GO:0016199 axon midline choice point recognition(GO:0016199) commissural neuron axon guidance(GO:0071679)
0.0 0.5 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.3 GO:0035108 hypothalamus cell differentiation(GO:0021979) limb morphogenesis(GO:0035108)
0.0 0.1 GO:0045922 negative regulation of fatty acid metabolic process(GO:0045922)
0.0 1.0 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.7 GO:0061726 mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0 0.8 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.1 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.0 0.2 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.9 GO:0008203 cholesterol metabolic process(GO:0008203)
0.0 0.2 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.0 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 1.3 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.3 GO:0006506 GPI anchor biosynthetic process(GO:0006506)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.2 0.9 GO:0034990 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.1 0.9 GO:0033010 paranodal junction(GO:0033010)
0.1 0.9 GO:0038039 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.1 0.8 GO:0016586 RSC complex(GO:0016586)
0.1 1.6 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 0.6 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 0.2 GO:0090443 FAR/SIN/STRIPAK complex(GO:0090443)
0.1 0.5 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.6 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.2 GO:0070724 BMP receptor complex(GO:0070724)
0.0 0.8 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.5 GO:0070187 telosome(GO:0070187)
0.0 1.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.6 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.1 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.2 GO:0071914 prominosome(GO:0071914)
0.0 0.9 GO:0008305 integrin complex(GO:0008305)
0.0 0.7 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.4 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.3 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.8 GO:0005811 lipid particle(GO:0005811)
0.0 0.8 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.8 GO:0030426 growth cone(GO:0030426)
0.0 0.7 GO:0032432 actin filament bundle(GO:0032432)
0.0 0.9 GO:0005871 kinesin complex(GO:0005871)
0.0 2.9 GO:0005764 lysosome(GO:0005764)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0000829 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.2 1.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.7 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 0.9 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.3 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 0.4 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 0.4 GO:0016519 gastric inhibitory peptide receptor activity(GO:0016519)
0.1 1.6 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.2 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 1.6 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 0.2 GO:0070336 flap-structured DNA binding(GO:0070336)
0.1 1.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.5 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.8 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.1 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.5 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.7 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.6 GO:0030507 spectrin binding(GO:0030507)
0.0 0.2 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.2 GO:0004997 thyrotropin-releasing hormone receptor activity(GO:0004997)
0.0 0.5 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.8 GO:0005178 integrin binding(GO:0005178)
0.0 0.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.2 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.8 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.0 0.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.6 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.4 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.7 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.7 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.3 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 0.3 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.5 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.6 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 1.4 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 0.6 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.6 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway
0.0 0.3 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.4 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.1 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.6 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.1 0.9 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.5 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.6 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.5 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.4 REACTOME KINESINS Genes involved in Kinesins
0.0 0.7 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.4 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.3 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.7 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production