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PRJNA207719: Tissue specific transcriptome profiling
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Results for foxh1+foxq1a+foxq1b
Z-value: 0.97
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Transcription factors associated with foxh1+foxq1a+foxq1b
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| foxh1 | dr11_v1_chr12_-_13730501_13730501 | 0.88 | 4.6e-02 | Click! |
| foxq1a | dr11_v1_chr2_-_722156_722170 | -0.45 | 4.5e-01 | Click! |
| foxq1b | dr11_v1_chr20_+_26683933_26683940 | -0.03 | 9.6e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr5_+_37837245 Show fit | 1.50 |
ENSDART00000171617
|
ependymin |
|
| chr16_-_28856112 Show fit | 0.75 |
ENSDART00000078543
|
synaptotagmin XIb |
|
| chr4_+_75200467 Show fit | 0.54 |
ENSDART00000122593
|
|
|
| chr15_+_7992906 Show fit | 0.54 |
ENSDART00000090790
|
cell adhesion molecule 2b |
|
| chr11_-_8126223 Show fit | 0.53 |
ENSDART00000091617
ENSDART00000192391 ENSDART00000101561 |
tubulin tyrosine ligase-like family, member 7 |
|
| chr6_-_9792004 Show fit | 0.50 |
ENSDART00000081129
|
cyclin-dependent kinase 15 |
|
| chr1_+_9290103 Show fit | 0.50 |
ENSDART00000055009
|
Unc4.1 homeobox (C. elegans) |
|
| chr17_+_15534815 Show fit | 0.49 |
ENSDART00000159426
|
myristoylated alanine-rich protein kinase C substrate b |
|
| chr25_+_7229046 Show fit | 0.47 |
ENSDART00000149965
ENSDART00000041820 |
leucine rich repeat and Ig domain containing 1a |
|
| chr9_+_31282161 Show fit | 0.46 |
ENSDART00000010774
|
zic family member 2 (odd-paired homolog, Drosophila), a |
Network of associatons between targets according to the STRING database.
First level regulatory network of foxh1+foxq1a+foxq1b
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.5 | GO:0007160 | cell-matrix adhesion(GO:0007160) |
| 0.0 | 0.9 | GO:0014059 | dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059) |
| 0.1 | 0.7 | GO:0070262 | peptidyl-serine dephosphorylation(GO:0070262) |
| 0.0 | 0.6 | GO:0018095 | protein polyglutamylation(GO:0018095) |
| 0.1 | 0.5 | GO:0021846 | cell proliferation in forebrain(GO:0021846) |
| 0.1 | 0.5 | GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083) |
| 0.0 | 0.5 | GO:0098943 | neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943) |
| 0.0 | 0.5 | GO:0051923 | sulfation(GO:0051923) |
| 0.0 | 0.5 | GO:0030968 | endoplasmic reticulum unfolded protein response(GO:0030968) |
| 0.0 | 0.5 | GO:0031103 | axon regeneration(GO:0031103) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.8 | GO:0043209 | myelin sheath(GO:0043209) |
| 0.0 | 0.7 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.1 | 0.6 | GO:0035101 | FACT complex(GO:0035101) |
| 0.0 | 0.5 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533) |
| 0.0 | 0.5 | GO:0036038 | MKS complex(GO:0036038) |
| 0.0 | 0.5 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.1 | 0.4 | GO:0016533 | cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533) |
| 0.0 | 0.3 | GO:0098844 | postsynaptic endocytic zone membrane(GO:0098844) |
| 0.0 | 0.3 | GO:0048788 | cytoskeleton of presynaptic active zone(GO:0048788) |
| 0.0 | 0.2 | GO:0005955 | calcineurin complex(GO:0005955) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.9 | GO:0031491 | nucleosome binding(GO:0031491) |
| 0.0 | 0.8 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
| 0.1 | 0.5 | GO:0008158 | hedgehog receptor activity(GO:0008158) |
| 0.0 | 0.5 | GO:0030332 | cyclin binding(GO:0030332) |
| 0.0 | 0.5 | GO:0070739 | protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740) |
| 0.0 | 0.4 | GO:0061575 | cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575) |
| 0.1 | 0.3 | GO:0047464 | heparosan-N-sulfate-glucuronate 5-epimerase activity(GO:0047464) |
| 0.0 | 0.3 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
| 0.1 | 0.2 | GO:0043621 | protein self-association(GO:0043621) |
| 0.0 | 0.2 | GO:0004133 | glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 0.0 | 0.2 | ST G ALPHA S PATHWAY | G alpha s Pathway |
| 0.0 | 0.2 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.6 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.1 | 0.5 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.0 | 0.4 | REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.0 | 0.3 | REACTOME AMINE DERIVED HORMONES | Genes involved in Amine-derived hormones |
| 0.0 | 0.2 | REACTOME ARMS MEDIATED ACTIVATION | Genes involved in ARMS-mediated activation |
| 0.0 | 0.2 | REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 0.0 | 0.1 | REACTOME PACKAGING OF TELOMERE ENDS | Genes involved in Packaging Of Telomere Ends |