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PRJNA207719: Tissue specific transcriptome profiling

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Results for foxd3

Z-value: 1.75

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Transcription factors associated with foxd3

Gene Symbol Gene ID Gene Info
ENSDARG00000021032 forkhead box D3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxd3dr11_v1_chr6_-_32093830_32093830-0.039.7e-01Click!

Activity profile of foxd3 motif

Sorted Z-values of foxd3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_30839763 1.44 ENSDART00000154228
SH3-domain GRB2-like (endophilin) interacting protein 1a
chr7_+_21787507 0.80 ENSDART00000100936
transmembrane protein 88 b
chr22_+_24559947 0.75 ENSDART00000169847
WD repeat domain 47b
chr4_-_6567355 0.74 ENSDART00000134820
ENSDART00000142087
forkhead box P2
chr5_+_36768674 0.73 ENSDART00000146854
MAP/microtubule affinity-regulating kinase 4a
chr18_-_23875370 0.64 ENSDART00000130163
nuclear receptor subfamily 2, group F, member 2
chr1_+_2190714 0.63 ENSDART00000132126
muscleblind-like splicing regulator 2
chr3_-_56924654 0.62 ENSDART00000157038
HID1 domain containing a
chr11_-_3646793 0.60 ENSDART00000077344
inter-alpha-trypsin inhibitor heavy chain 1
chr4_+_7391400 0.59 ENSDART00000169111
ENSDART00000186395
troponin I4a
chr4_+_7391110 0.58 ENSDART00000160708
ENSDART00000187823
troponin I4a
chr19_+_1510971 0.56 ENSDART00000157721
solute carrier family 45 member 4
chr23_+_36653376 0.56 ENSDART00000053189
G protein-coupled receptor 182
chr7_+_31838320 0.54 ENSDART00000144679
ENSDART00000174217
ENSDART00000122506
myosin binding protein C, cardiac
chr15_+_42431198 0.54 ENSDART00000189951
ENSDART00000089694
T cell lymphoma invasion and metastasis 1b
chr23_+_19590006 0.51 ENSDART00000021231
sarcolemma associated protein b
chr15_+_16908085 0.50 ENSDART00000186870
yippee-like 2b
chr1_+_16396870 0.50 ENSDART00000189245
ENSDART00000113266
mitochondrial calcium uptake family, member 3a
chr24_+_25692802 0.49 ENSDART00000190493
calcium/calmodulin-dependent protein kinase II inhibitor 2
chr14_-_33454595 0.49 ENSDART00000109615
ENSDART00000173267
ENSDART00000185737
ENSDART00000190989
transmembrane protein 255A
chr17_+_24111392 0.48 ENSDART00000180123
ENSDART00000182787
ENSDART00000189752
ENSDART00000184940
ENSDART00000185363
ENSDART00000064067
EH domain binding protein 1
chr5_-_13766651 0.47 ENSDART00000134064
MAX dimerization protein 1
chr7_-_26087807 0.47 ENSDART00000052989
acetylcholinesterase
chr16_-_28856112 0.47 ENSDART00000078543
synaptotagmin XIb
chr18_-_23875219 0.46 ENSDART00000059976
nuclear receptor subfamily 2, group F, member 2
chr23_-_10137322 0.46 ENSDART00000142442
plexin b1a
chr6_+_24817852 0.45 ENSDART00000165609
BarH-like homeobox 2
chr21_+_21906671 0.45 ENSDART00000016916
glutamate receptor, ionotropic, AMPA 4b
chr20_-_9462433 0.44 ENSDART00000152674
ENSDART00000040557
zgc:101840
chr7_-_49594995 0.43 ENSDART00000174161
ENSDART00000109147
BR serine/threonine kinase 2b
chr11_-_18323059 0.43 ENSDART00000182590
Scm like with four mbt domains 1
chr1_-_9114936 0.42 ENSDART00000163624
ENSDART00000132910
si:ch211-14k19.8
vascular associated protein
chr20_-_28800999 0.42 ENSDART00000049462
RAB15, member RAS oncogene family
chr9_-_31915423 0.42 ENSDART00000060051
fibroblast growth factor 14
chr8_-_34065573 0.41 ENSDART00000186946
pre-B-cell leukemia homeobox 3b
chr23_+_25879320 0.41 ENSDART00000124963
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr19_-_44091405 0.41 ENSDART00000132800
RAD21 cohesin complex component b
chr25_+_28158352 0.40 ENSDART00000151854
Ca++-dependent secretion activator 2
chr23_+_17800717 0.40 ENSDART00000122654
ENSDART00000044986
Rho family GTPase 1a
chr15_+_31701716 0.40 ENSDART00000113370
beta 3-glucosyltransferase a
chr17_+_8988374 0.40 ENSDART00000109573
A kinase (PRKA) anchor protein 6
chr6_+_51932563 0.39 ENSDART00000181778
angiopoietin 4
chr7_+_26138240 0.39 ENSDART00000193750
ENSDART00000184942
N-acetyltransferase 16
chr2_-_37043540 0.39 ENSDART00000131834
guanine nucleotide binding protein (G protein), gamma 7
chr5_-_38384289 0.39 ENSDART00000135260
misshapen-like kinase 1
chr7_-_48263516 0.38 ENSDART00000006619
ENSDART00000142370
ENSDART00000148273
ENSDART00000147968
RNA binding protein with multiple splicing 2b
chr20_-_29474859 0.38 ENSDART00000152906
ENSDART00000045249
secretogranin V
chr17_+_14965570 0.37 ENSDART00000066604
G protein-coupled receptor 137c
chr25_-_14433503 0.37 ENSDART00000103957
exocyst complex component 3-like 1
chr4_-_19028861 0.37 ENSDART00000166374
si:dkey-31f5.11
chr20_-_29475172 0.37 ENSDART00000183164
secretogranin V
chr19_-_47527093 0.37 ENSDART00000171379
ENSDART00000171140
ENSDART00000114886
secretogranin V
chr19_-_47526737 0.37 ENSDART00000186636
secretogranin V
chr7_+_37372479 0.37 ENSDART00000173652
spalt-like transcription factor 1a
chr20_-_9980318 0.37 ENSDART00000080664
zgc:86709
chr4_-_6623645 0.36 ENSDART00000060861
forkhead box P2
chr8_-_52413032 0.36 ENSDART00000183039

chr11_+_35364445 0.36 ENSDART00000125766
CaM kinase-like vesicle-associated b
chr8_+_26818446 0.36 ENSDART00000134987
ENSDART00000138835
si:ch211-156j16.1
chr9_+_38967248 0.36 ENSDART00000112298
microtubule-associated protein 2
chr3_-_41292275 0.35 ENSDART00000144088
sidekick cell adhesion molecule 1a
chr14_-_1990290 0.35 ENSDART00000183382
protocadherin 2 gamma 5
chr1_-_30039331 0.35 ENSDART00000086935
ENSDART00000143800
zgc:153256
chr14_+_7452302 0.35 ENSDART00000130388
GDNF family receptor alpha 3
chr18_-_23874929 0.35 ENSDART00000134910
nuclear receptor subfamily 2, group F, member 2
chr24_-_41320037 0.35 ENSDART00000129058
Ras homolog, mTORC1 binding
chr17_+_26981132 0.35 ENSDART00000156672
si:dkey-221l4.11
chr5_-_25406807 0.35 ENSDART00000089748
RAR-related orphan receptor B
chr10_+_21789954 0.34 ENSDART00000157769
ENSDART00000171703
protocadherin 1 gamma c 5
chr25_+_15647993 0.34 ENSDART00000186578
ENSDART00000031828
spondin 1b
chr2_+_34967022 0.34 ENSDART00000134926
astrotactin 1
chr17_+_53250802 0.33 ENSDART00000143819
vasohibin 1
chr1_-_50611031 0.33 ENSDART00000148285
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr5_+_46196147 0.33 ENSDART00000084112
coagulation factor II (thrombin) receptor
chr4_-_13921185 0.33 ENSDART00000143202
ENSDART00000080334
YY1 associated factor 2
chr11_+_40032790 0.33 ENSDART00000158809
si:dkey-264d12.1
chr3_-_22191132 0.33 ENSDART00000154226
ENSDART00000155528
ENSDART00000155190
microtubule-associated protein tau b
chr8_+_41647539 0.33 ENSDART00000136492
ENSDART00000138799
ENSDART00000134404
si:ch211-158d24.4
chr2_-_37043905 0.33 ENSDART00000056514
guanine nucleotide binding protein (G protein), gamma 7
chr12_+_5081759 0.32 ENSDART00000164178
proline-rich transmembrane protein 2
chr1_-_51606552 0.32 ENSDART00000130828
cannabinoid receptor interacting protein 1a
chr7_-_51546386 0.32 ENSDART00000174306
NHS-like 2
chr2_+_18988407 0.32 ENSDART00000170216
glutamate-ammonia ligase (glutamine synthase) a
chr10_+_17850934 0.32 ENSDART00000113666
ENSDART00000145936
PHD finger protein 24
chr9_-_29844596 0.32 ENSDART00000138574
interleukin 1 receptor accessory protein-like 1a
chr12_+_42574148 0.32 ENSDART00000157855
early B cell factor 3a
chr14_+_21783229 0.32 ENSDART00000170784
ankyrin repeat domain 13 family, member D
chr6_-_25201810 0.31 ENSDART00000168683
leucine rich repeat containing 8 VRAC subunit C
chr5_-_23277939 0.31 ENSDART00000003514
proteolipid protein 1b
chr17_-_6399920 0.31 ENSDART00000022010
human immunodeficiency virus type I enhancer binding protein 2b
chr3_+_24361096 0.31 ENSDART00000132387
parvalbumin 6
chr11_+_14199802 0.31 ENSDART00000102520
ENSDART00000133172
paralemmin 1a
chr21_+_41743493 0.31 ENSDART00000192669
protein phosphatase 2, regulatory subunit B, beta b
chr11_-_43226255 0.31 ENSDART00000172929
spectrin, beta, non-erythrocytic 1
chr22_-_21755524 0.31 ENSDART00000149635
transducin like enhancer of split 2b
chr13_+_22280983 0.31 ENSDART00000173258
ENSDART00000173379
ubiquitin specific peptidase 54a
chr6_+_51932267 0.30 ENSDART00000156256
angiopoietin 4
chr2_+_55982940 0.30 ENSDART00000097753
ENSDART00000097751
nicotinamide riboside kinase 2
chr2_-_8017579 0.30 ENSDART00000040209
eph receptor B3a
chr14_-_32016615 0.30 ENSDART00000105761
zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila)
chr8_-_53896982 0.30 ENSDART00000169206
mindbomb E3 ubiquitin protein ligase 2
chr20_-_26042070 0.30 ENSDART00000140255
si:dkey-12h9.6
chr2_+_5563077 0.30 ENSDART00000111220
Mab-21 domain containing 2
chr13_+_38430466 0.29 ENSDART00000132691
adhesion G protein-coupled receptor B3
chr19_+_2275019 0.29 ENSDART00000136138
integrin, beta 8
chr17_-_8727699 0.29 ENSDART00000049236
ENSDART00000149505
ENSDART00000148619
ENSDART00000149668
ENSDART00000148827
C-terminal binding protein 2a
chr12_+_13405445 0.29 ENSDART00000089042
potassium voltage-gated channel, subfamily H (eag-related), member 4b
chr12_-_37734973 0.29 ENSDART00000140353
sidekick cell adhesion molecule 2b
chr22_+_12361317 0.29 ENSDART00000189963
ENSDART00000159614
R3H domain containing 1
chr13_+_31497236 0.29 ENSDART00000146752
leucine rich repeat containing 9
chr16_+_47207691 0.29 ENSDART00000062507
islet cell autoantigen 1
chr10_-_8032885 0.29 ENSDART00000188619
ATPase H+ transporting V0 subunit a2a
chr13_+_23214100 0.29 ENSDART00000163393
sorbin and SH3 domain containing 1
chr20_+_29743904 0.29 ENSDART00000146366
ENSDART00000153154
kinase D-interacting substrate 220b
chr14_+_21783400 0.29 ENSDART00000164023
ankyrin repeat domain 13 family, member D
chr6_-_50204262 0.29 ENSDART00000163648
RALY heterogeneous nuclear ribonucleoprotein
chr5_+_23118470 0.29 ENSDART00000149893
neurite extension and migration factor a
chr23_-_9925568 0.29 ENSDART00000081268
si:ch211-220i18.4
chr13_-_31452516 0.29 ENSDART00000193268
reticulon 1a
chr12_-_26430507 0.29 ENSDART00000153214
synaptopodin 2-like b
chr23_+_19564392 0.29 ENSDART00000144746
ATPase H+ transporting accessory protein 1 like b
chr1_+_44710955 0.28 ENSDART00000131296
ENSDART00000142187
structure specific recognition protein 1b
chr5_-_38384755 0.28 ENSDART00000188573
ENSDART00000051233
misshapen-like kinase 1
chr10_+_33982010 0.28 ENSDART00000180431
furry homolog b (Drosophila)
chr3_-_41292569 0.28 ENSDART00000111856
sidekick cell adhesion molecule 1a
chr16_+_34523515 0.28 ENSDART00000041007
stathmin 1b
chr10_+_3875716 0.28 ENSDART00000189268
ENSDART00000180624
tetratricopeptide repeat domain 28
chr10_-_34772211 0.28 ENSDART00000145450
ENSDART00000134307
doublecortin-like kinase 1a
chr7_+_60551133 0.28 ENSDART00000148038
leucine rich repeat and fibronectin type III domain containing 4b
chr9_-_33785093 0.28 ENSDART00000140779
ENSDART00000059837
FUN14 domain containing 1
chr6_-_39167732 0.28 ENSDART00000153626
apolipoprotein F
chr17_+_15433518 0.28 ENSDART00000026180
fatty acid binding protein 7, brain, a
chr4_-_75157223 0.28 ENSDART00000174127

chr17_+_9017775 0.28 ENSDART00000186901
ENSDART00000185407
A kinase (PRKA) anchor protein 6
chr23_+_22873415 0.28 ENSDART00000135130
arginine-glutamic acid dipeptide (RE) repeats a
chr5_-_26566435 0.28 ENSDART00000146070
ARVCF, delta catenin family member b
chr11_-_25829712 0.28 ENSDART00000103549
v-ski avian sarcoma viral oncogene homolog b
chr6_+_32393057 0.27 ENSDART00000190765
dedicator of cytokinesis 7
chr4_-_2868112 0.27 ENSDART00000133843
phosphodiesterase 3A, cGMP-inhibited
chr15_-_20933574 0.27 ENSDART00000152648
ENSDART00000152448
ENSDART00000152244
ubiquitin specific peptidase 2a
chr8_+_694218 0.27 ENSDART00000147753
ring finger protein 165b
chr19_-_28789404 0.27 ENSDART00000191453
ENSDART00000026992
SRY (sex determining region Y)-box 4a
chr4_+_10365857 0.27 ENSDART00000138890
potassium voltage-gated channel, Shal-related subfamily, member 2
chr1_+_36651059 0.27 ENSDART00000187475
endothelin receptor type Aa
chr2_-_41723487 0.27 ENSDART00000170171
zgc:110158
chr25_-_13789955 0.27 ENSDART00000167742
ENSDART00000165116
ENSDART00000171461
cytoskeleton associated protein 5
chr20_-_45062514 0.27 ENSDART00000183529
ENSDART00000182955
kelch-like family member 29
chr7_+_38811800 0.27 ENSDART00000052322
zgc:110699
chr4_+_8797197 0.27 ENSDART00000158671
sulfotransferase family 4A, member 1
chr23_+_42813415 0.27 ENSDART00000055577
myosin, light chain 9a, regulatory
chr20_-_42203629 0.27 ENSDART00000074959
solute carrier family 35, member F1
chr20_-_39273505 0.27 ENSDART00000153114
clusterin
chr16_-_13622794 0.27 ENSDART00000146953
si:dkeyp-69b9.6
chr18_-_7137153 0.27 ENSDART00000019571
CD9 molecule a
chr24_+_13017586 0.27 ENSDART00000142457
staufen double-stranded RNA binding protein 2
chr20_-_14925281 0.27 ENSDART00000152641
dynamin 3a
chr16_+_50969248 0.27 ENSDART00000172068
si:dkeyp-97a10.2
chr9_+_31282161 0.27 ENSDART00000010774
zic family member 2 (odd-paired homolog, Drosophila), a
chr23_+_23918421 0.27 ENSDART00000046951
protein tyrosine phosphatase, non-receptor type 11, b
chr8_-_13210959 0.27 ENSDART00000142224
si:ch73-61d6.3
chr20_+_34537736 0.27 ENSDART00000152982
si:ch211-242b18.1
chr12_+_13404784 0.26 ENSDART00000167977
potassium voltage-gated channel, subfamily H (eag-related), member 4b
chr5_+_25952340 0.26 ENSDART00000147188
transient receptor potential cation channel, subfamily M, member 3
chr5_-_14564878 0.26 ENSDART00000160511
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr14_+_34966598 0.26 ENSDART00000004550
ring finger protein 145a
chr4_-_20521441 0.26 ENSDART00000066895
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8b
chr18_-_893574 0.26 ENSDART00000150959
poly (ADP-ribose) polymerase family, member 6a
chr2_+_30894595 0.26 ENSDART00000132645
ENSDART00000182303
charged multivesicular body protein 5a
chr22_+_30184039 0.26 ENSDART00000049075
adducin 3 (gamma) a
chr14_-_2348917 0.26 ENSDART00000159004
si:ch73-233f7.8
chr21_-_42202792 0.26 ENSDART00000124708
gamma-aminobutyric acid (GABA) A receptor, alpha 6b
chr6_+_27146671 0.26 ENSDART00000156792
kinesin family member 1Aa
chr15_+_42397125 0.26 ENSDART00000169751
T cell lymphoma invasion and metastasis 1b
chr8_+_16025554 0.26 ENSDART00000110171
ELAV like neuron-specific RNA binding protein 4
chr21_-_18648861 0.25 ENSDART00000112113
si:dkey-112m2.1
chr25_+_15647750 0.25 ENSDART00000137375
spondin 1b
chr18_+_17660402 0.25 ENSDART00000143475
copine II
chr6_+_39222598 0.25 ENSDART00000154991
beta-1,4-N-acetyl-galactosaminyl transferase 1b
chr6_-_14038804 0.25 ENSDART00000184606
ENSDART00000184609
ets variant 5b
chr16_+_31853919 0.25 ENSDART00000133886
atrophin 1
chr14_-_32258759 0.25 ENSDART00000052949
fibroblast growth factor 13a
chr11_-_6974022 0.25 ENSDART00000172851
si:ch211-43f4.1
chr19_-_8880688 0.25 ENSDART00000039629
cugbp, Elav-like family member 3a
chr16_-_563235 0.25 ENSDART00000016303
iroquois homeobox 2a
chr13_-_22771708 0.25 ENSDART00000112900
si:ch211-150i13.1
chr17_-_37474689 0.25 ENSDART00000103980
cysteine-rich protein 2
chr9_+_38967998 0.25 ENSDART00000135581
microtubule-associated protein 2
chr15_+_29662401 0.25 ENSDART00000135540
nuclear receptor interacting protein 1a
chr24_-_33756003 0.25 ENSDART00000079283
transmembrane protein with EGF-like and two follistatin-like domains 1b
chr20_-_31252809 0.25 ENSDART00000137236
hippocalcin-like 1
chr23_-_30045661 0.25 ENSDART00000122239
ENSDART00000103480
coiled-coil domain containing 187
chr17_-_14966384 0.25 ENSDART00000105064
thioredoxin domain containing 16
chr5_+_43470544 0.25 ENSDART00000111587
Rho-related BTB domain containing 2a
chr9_+_13714379 0.25 ENSDART00000017593
ENSDART00000145503
transmembrane protein 237a
chr16_+_28383758 0.25 ENSDART00000059038
ENSDART00000141061
integrin, alpha 8
chr15_+_29393519 0.24 ENSDART00000193488
ENSDART00000112375
glycerophosphodiester phosphodiesterase domain containing 5b
chr7_+_32369026 0.24 ENSDART00000169588
leucine-rich repeat containing G protein-coupled receptor 4
chr14_-_21660548 0.24 ENSDART00000161713
ENSDART00000089845
lysine (K)-specific demethylase 3B
chr13_-_46991577 0.24 ENSDART00000114748
vasoactive intestinal peptide
chr11_+_3006124 0.24 ENSDART00000126071
copine Vb

Network of associatons between targets according to the STRING database.

First level regulatory network of foxd3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0060838 lymphatic endothelial cell fate commitment(GO:0060838) venous endothelial cell differentiation(GO:0060843) venous endothelial cell fate commitment(GO:0060845)
0.1 0.5 GO:0008291 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.1 0.3 GO:1901533 negative regulation of hematopoietic progenitor cell differentiation(GO:1901533)
0.1 0.5 GO:0003210 cardiac atrium formation(GO:0003210)
0.1 0.5 GO:0051148 negative regulation of muscle cell differentiation(GO:0051148)
0.1 0.5 GO:0016322 neuron remodeling(GO:0016322)
0.1 0.5 GO:0051703 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.1 1.1 GO:0045471 response to ethanol(GO:0045471)
0.1 0.4 GO:0021888 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.1 0.4 GO:0023041 neuronal signal transduction(GO:0023041)
0.1 0.3 GO:2000048 negative regulation of cell-substrate adhesion(GO:0010812) negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 0.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.3 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 0.5 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.1 0.9 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.2 GO:1903792 regulation of neurotransmitter uptake(GO:0051580) negative regulation of anion transport(GO:1903792)
0.1 0.2 GO:0042908 xenobiotic transport(GO:0042908)
0.1 0.2 GO:0060405 copulation(GO:0007620) regulation of epinephrine secretion(GO:0014060) positive regulation of epinephrine secretion(GO:0032812) positive regulation of catecholamine secretion(GO:0033605) penile erection(GO:0043084) epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242) positive regulation of amine transport(GO:0051954) regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406) prolactin secretion(GO:0070459)
0.1 0.2 GO:0060986 regulation of endocrine process(GO:0044060) endocrine hormone secretion(GO:0060986)
0.1 0.4 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 0.2 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.1 0.1 GO:2000402 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869) negative regulation of lymphocyte migration(GO:2000402) negative regulation of T cell migration(GO:2000405)
0.1 0.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 0.2 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.1 0.2 GO:0009098 leucine biosynthetic process(GO:0009098)
0.1 0.5 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.1 0.4 GO:0043584 nose development(GO:0043584)
0.1 1.6 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.3 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.2 GO:0060074 synapse maturation(GO:0060074)
0.0 0.2 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.0 1.8 GO:0046883 regulation of hormone secretion(GO:0046883)
0.0 0.1 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.2 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.0 0.3 GO:0046637 regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043370) regulation of alpha-beta T cell differentiation(GO:0046637)
0.0 0.1 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.1 GO:0070131 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
0.0 0.4 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.1 GO:0019852 L-ascorbic acid transport(GO:0015882) L-ascorbic acid metabolic process(GO:0019852)
0.0 0.2 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.3 GO:0016048 detection of temperature stimulus(GO:0016048) sensory perception of temperature stimulus(GO:0050951)
0.0 0.1 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
0.0 0.6 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 0.3 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.0 0.1 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.3 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.0 0.1 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.0 0.1 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.0 0.2 GO:0010226 response to lithium ion(GO:0010226)
0.0 0.3 GO:0097476 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.0 0.3 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.1 GO:0021530 spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0 0.2 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.0 0.1 GO:0061400 positive regulation of transcription from RNA polymerase II promoter in response to calcium ion(GO:0061400)
0.0 0.2 GO:0006788 heme oxidation(GO:0006788)
0.0 0.1 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.3 GO:0045920 negative regulation of exocytosis(GO:0045920)
0.0 0.2 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.2 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.0 0.2 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.0 0.2 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.0 0.1 GO:0031642 negative regulation of myelination(GO:0031642) negative regulation of neurological system process(GO:0031645)
0.0 0.1 GO:0098920 endocannabinoid signaling pathway(GO:0071926) retrograde trans-synaptic signaling by lipid(GO:0098920) retrograde trans-synaptic signaling by endocannabinoid(GO:0098921)
0.0 0.1 GO:0090155 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.0 0.3 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.2 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.0 0.2 GO:0099612 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.0 0.3 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.8 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.1 GO:0006678 glucosylceramide metabolic process(GO:0006678)
0.0 0.1 GO:0036076 ligamentous ossification(GO:0036076)
0.0 0.3 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0010039 response to iron ion(GO:0010039)
0.0 0.2 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.2 GO:1901909 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.1 GO:1903538 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.0 0.2 GO:0045299 otolith mineralization(GO:0045299)
0.0 0.1 GO:0060220 retinal cone cell fate determination(GO:0042671) eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate determination(GO:0043703) retinal cone cell fate commitment(GO:0046551) photoreceptor cell fate commitment(GO:0046552) camera-type eye photoreceptor cell fate commitment(GO:0060220)
0.0 0.1 GO:0035521 monoubiquitinated protein deubiquitination(GO:0035520) monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.3 GO:0021576 hindbrain formation(GO:0021576)
0.0 0.2 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 1.1 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.2 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.0 0.5 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:0034405 response to fluid shear stress(GO:0034405)
0.0 0.3 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 0.1 GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175) negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902176)
0.0 0.5 GO:1902287 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0 0.2 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.1 GO:0042306 regulation of protein import into nucleus(GO:0042306) negative regulation of protein import into nucleus(GO:0042308) negative regulation of nucleocytoplasmic transport(GO:0046823) negative regulation of protein localization to nucleus(GO:1900181) regulation of protein import(GO:1904589) negative regulation of protein import(GO:1904590)
0.0 0.1 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.9 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0034164 regulation of toll-like receptor 9 signaling pathway(GO:0034163) negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.0 0.4 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.1 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.2 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.1 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.3 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.2 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0 0.4 GO:0042670 retinal cone cell differentiation(GO:0042670)
0.0 0.1 GO:0007008 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.2 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.1 GO:0010754 negative regulation of cGMP-mediated signaling(GO:0010754)
0.0 0.1 GO:0061316 canonical Wnt signaling pathway involved in heart development(GO:0061316)
0.0 0.1 GO:0003311 pancreatic D cell differentiation(GO:0003311) pancreatic epsilon cell differentiation(GO:0090104)
0.0 0.4 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.0 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0 0.1 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.2 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.0 0.4 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.1 GO:2000639 response to sterol(GO:0036314) cellular response to sterol(GO:0036315) SREBP-SCAP complex retention in endoplasmic reticulum(GO:0036316) regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.2 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.0 0.5 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.1 GO:0009450 gamma-aminobutyric acid catabolic process(GO:0009450)
0.0 0.3 GO:0007035 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.0 0.1 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.1 GO:0001120 DNA-templated transcriptional open complex formation(GO:0001112) transcriptional open complex formation at RNA polymerase II promoter(GO:0001113) protein-DNA complex remodeling(GO:0001120)
0.0 0.6 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.9 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.0 0.1 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.3 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) positive regulation of mRNA catabolic process(GO:0061014) regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.1 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.0 1.0 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.1 GO:0046959 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.0 0.1 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.2 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.4 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 1.2 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 0.1 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.2 GO:0001881 receptor recycling(GO:0001881)
0.0 0.9 GO:0007416 synapse assembly(GO:0007416)
0.0 0.1 GO:0036268 swimming(GO:0036268)
0.0 0.1 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.2 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.0 1.2 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.2 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.2 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.1 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.1 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.2 GO:1904356 regulation of telomere maintenance via telomere lengthening(GO:1904356)
0.0 0.4 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.3 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.1 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.2 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
0.0 0.2 GO:0071679 commissural neuron axon guidance(GO:0071679)
0.0 0.4 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.2 GO:1900077 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.3 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.1 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.0 0.2 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.3 GO:0031100 organ regeneration(GO:0031100)
0.0 0.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:1900118 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.2 GO:0072160 pronephric nephron tubule epithelial cell differentiation(GO:0035778) cell differentiation involved in pronephros development(GO:0039014) nephron tubule epithelial cell differentiation(GO:0072160)
0.0 0.1 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.2 GO:0006265 DNA topological change(GO:0006265)
0.0 0.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.2 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 0.1 GO:0031111 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.0 0.0 GO:0031591 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.0 0.1 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.1 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.1 GO:0042403 thyroid hormone metabolic process(GO:0042403)
0.0 0.3 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.0 0.2 GO:0021508 floor plate formation(GO:0021508) floor plate morphogenesis(GO:0033505)
0.0 0.3 GO:0060841 venous blood vessel development(GO:0060841)
0.0 0.1 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.0 0.1 GO:1900744 regulation of p38MAPK cascade(GO:1900744)
0.0 0.1 GO:0046688 response to copper ion(GO:0046688)
0.0 0.1 GO:0043490 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.0 0.0 GO:1903334 regulation of protein folding(GO:1903332) positive regulation of protein folding(GO:1903334) regulation of chaperone-mediated protein folding(GO:1903644) positive regulation of chaperone-mediated protein folding(GO:1903646)
0.0 0.8 GO:0021954 central nervous system neuron development(GO:0021954)
0.0 0.1 GO:0000012 single strand break repair(GO:0000012)
0.0 0.1 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 0.1 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.4 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.0 GO:0009258 10-formyltetrahydrofolate metabolic process(GO:0009256) 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.0 0.0 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.2 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.0 0.1 GO:0006868 glutamine transport(GO:0006868)
0.0 0.1 GO:0042311 vasodilation(GO:0042311)
0.0 0.2 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.1 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.0 0.1 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.0 0.1 GO:0061709 reticulophagy(GO:0061709)
0.0 0.2 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0002082 regulation of oxidative phosphorylation(GO:0002082)
0.0 0.4 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.2 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.2 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 0.0 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 0.1 GO:0015886 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.0 0.1 GO:0043462 regulation of ATPase activity(GO:0043462)
0.0 0.1 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.0 GO:0016554 cytidine to uridine editing(GO:0016554) positive regulation of DNA binding(GO:0043388) positive regulation of binding(GO:0051099)
0.0 0.9 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.1 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.2 GO:0015833 peptide transport(GO:0015833)
0.0 0.3 GO:0051923 sulfation(GO:0051923)
0.0 0.1 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 1.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.0 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.0 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.1 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.2 GO:1902307 positive regulation of sodium ion transport(GO:0010765) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 0.4 GO:0034990 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.1 0.3 GO:0008091 spectrin(GO:0008091)
0.1 0.4 GO:0002139 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142) stereocilium tip(GO:0032426)
0.1 0.2 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.2 GO:0016600 flotillin complex(GO:0016600)
0.1 0.2 GO:0032584 growth cone membrane(GO:0032584)
0.1 0.3 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 0.2 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.3 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.8 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.3 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.0 0.4 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.0 0.4 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.2 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.0 0.2 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.2 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.4 GO:1990246 uniplex complex(GO:1990246)
0.0 0.1 GO:0016460 myosin II complex(GO:0016460)
0.0 0.1 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 1.2 GO:0043204 perikaryon(GO:0043204)
0.0 0.3 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.3 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.2 GO:0016586 RSC complex(GO:0016586)
0.0 0.1 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 0.5 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.1 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.0 0.2 GO:0001650 fibrillar center(GO:0001650)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 1.4 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.2 GO:0033010 paranodal junction(GO:0033010)
0.0 0.1 GO:0070724 BMP receptor complex(GO:0070724)
0.0 1.5 GO:0030141 secretory granule(GO:0030141)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.1 GO:0005845 mRNA cap binding complex(GO:0005845)
0.0 0.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.3 GO:0043209 myelin sheath(GO:0043209)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.1 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.1 GO:0060171 stereocilium membrane(GO:0060171)
0.0 0.1 GO:1990745 EARP complex(GO:1990745)
0.0 1.2 GO:0030427 site of polarized growth(GO:0030427)
0.0 0.1 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.3 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)
0.0 0.2 GO:0070187 telosome(GO:0070187)
0.0 0.5 GO:0043679 axon terminus(GO:0043679)
0.0 0.4 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.1 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.3 GO:0045180 basal cortex(GO:0045180)
0.0 0.1 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.1 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.1 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510) clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.0 GO:0072380 TRC complex(GO:0072380)
0.0 0.1 GO:0038039 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.0 0.6 GO:0008305 integrin complex(GO:0008305)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.0 0.2 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.0 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.7 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.1 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.1 GO:0000938 GARP complex(GO:0000938)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 GO:0001972 retinoic acid binding(GO:0001972)
0.2 0.5 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
0.1 0.5 GO:0010858 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.1 0.5 GO:0004104 cholinesterase activity(GO:0004104)
0.1 0.5 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.1 0.4 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 0.2 GO:0043621 protein self-association(GO:0043621)
0.1 0.5 GO:0004962 endothelin receptor activity(GO:0004962)
0.1 0.7 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.4 GO:0098809 nitrite reductase activity(GO:0098809)
0.1 0.2 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 1.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.3 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.2 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263) beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.1 GO:1990174 phosphodiesterase decapping endonuclease activity(GO:1990174)
0.0 1.4 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.3 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.5 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.1 GO:0046978 TAP1 binding(GO:0046978)
0.0 0.2 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
0.0 0.2 GO:0000829 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.5 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.3 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.2 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.3 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.8 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.1 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.5 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.5 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.1 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.2 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.2 GO:0034431 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 0.3 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.5 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0035197 siRNA binding(GO:0035197)
0.0 0.1 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0 0.1 GO:0047777 (3S)-citramalyl-CoA lyase activity(GO:0047777)
0.0 0.1 GO:0047453 ATP-dependent NAD(P)H-hydrate dehydratase activity(GO:0047453) ADP-dependent NAD(P)H-hydrate dehydratase activity(GO:0052855)
0.0 0.1 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.2 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.1 GO:0070336 flap-structured DNA binding(GO:0070336)
0.0 0.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.1 GO:0031690 adrenergic receptor binding(GO:0031690)
0.0 0.5 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.1 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.1 GO:0004997 thyrotropin-releasing hormone receptor activity(GO:0004997)
0.0 0.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.1 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.0 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.3 GO:0051117 ATPase binding(GO:0051117)
0.0 0.3 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.2 GO:0015386 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.3 GO:0070740 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.3 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.0 0.2 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.2 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0017020 myosin phosphatase regulator activity(GO:0017020)
0.0 0.9 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.1 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.1 GO:0030507 spectrin binding(GO:0030507)
0.0 1.0 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.1 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.2 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.0 0.2 GO:2001069 glycogen binding(GO:2001069)
0.0 0.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.2 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596)
0.0 0.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.2 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.2 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.5 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:0002039 p53 binding(GO:0002039)
0.0 0.1 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0030619 U1 snRNA binding(GO:0030619)
0.0 0.1 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.0 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.0 0.2 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.1 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.2 GO:0008242 omega peptidase activity(GO:0008242)
0.0 1.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.1 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.7 GO:0005178 integrin binding(GO:0005178)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0042936 oligopeptide transporter activity(GO:0015198) oligopeptide transmembrane transporter activity(GO:0035673) dipeptide transporter activity(GO:0042936) dipeptide transmembrane transporter activity(GO:0071916)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.2 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.1 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.2 GO:0019870 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 0.3 GO:0030971 receptor tyrosine kinase binding(GO:0030971)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.7 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 1.1 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.9 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.2 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.4 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.2 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.5 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.6 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.3 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.4 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.2 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.4 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.3 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.6 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.4 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.2 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 0.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.9 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.5 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.3 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.1 REACTOME DEFENSINS Genes involved in Defensins
0.0 0.7 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.2 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.1 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 1.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.0 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.0 0.2 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.5 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.3 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.3 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.1 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism