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PRJNA207719: Tissue specific transcriptome profiling

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Results for foxb1b+foxb2

Z-value: 1.51

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Transcription factors associated with foxb1b+foxb2

Gene Symbol Gene ID Gene Info
ENSDARG00000037475 forkhead box B2
ENSDARG00000053650 forkhead box B1b
ENSDARG00000110408 forkhead box B1b
ENSDARG00000113373 forkhead box B1b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxb2dr11_v1_chr8_-_38506339_385063390.847.6e-02Click!
foxb1bdr11_v1_chr7_+_29461060_294610600.454.4e-01Click!

Activity profile of foxb1b+foxb2 motif

Sorted Z-values of foxb1b+foxb2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr23_-_19953089 1.57 ENSDART00000153828
ATPase plasma membrane Ca2+ transporting 3b
chr2_-_8017579 1.28 ENSDART00000040209
eph receptor B3a
chr6_+_40671336 1.20 ENSDART00000111639
ENSDART00000186617
arginine-glutamic acid dipeptide (RE) repeats b
chr12_+_28367557 1.18 ENSDART00000066294
cyclin-dependent kinase 5, regulatory subunit 1b (p35)
chr21_+_11684830 1.08 ENSDART00000147473
proprotein convertase subtilisin/kexin type 1
chr23_-_29502287 1.03 ENSDART00000141075
ENSDART00000053807
kinesin family member 1B
chr21_+_11685009 1.02 ENSDART00000014668
proprotein convertase subtilisin/kexin type 1
chr7_+_22823889 1.01 ENSDART00000127467
ENSDART00000148576
ENSDART00000149993
phosphorylase, glycogen, muscle b
chr1_+_16127825 0.96 ENSDART00000122503
tumor suppressor candidate 3
chr23_-_3703569 0.95 ENSDART00000143731
protein kinase C and casein kinase substrate in neurons 1a
chr1_+_25801648 0.94 ENSDART00000129471
guanylate cyclase 1 soluble subunit beta 1
chr20_-_34801181 0.93 ENSDART00000048375
ENSDART00000132426
stathmin-like 4
chr7_+_48288762 0.91 ENSDART00000083569
ornithine decarboxylase antizyme 2b
chr6_-_9792004 0.90 ENSDART00000081129
cyclin-dependent kinase 15
chr23_-_27633730 0.89 ENSDART00000103639
ADP-ribosylation factor 3a
chr17_-_20287530 0.88 ENSDART00000078703
ENSDART00000191289
adducin 3 (gamma) b
chr14_-_7885707 0.86 ENSDART00000029981
protein phosphatase 3, catalytic subunit, beta isozyme
chr15_+_8043751 0.83 ENSDART00000193701
cell adhesion molecule 2b
chr4_+_8797197 0.82 ENSDART00000158671
sulfotransferase family 4A, member 1
chr2_+_26240339 0.82 ENSDART00000191006
paralemmin 1b
chr3_+_34821327 0.80 ENSDART00000055262
cyclin-dependent kinase 5, regulatory subunit 1a (p35)
chr8_+_41533268 0.79 ENSDART00000142377
si:ch211-158d24.2
chr15_-_18574716 0.79 ENSDART00000142010
ENSDART00000019006
neural cell adhesion molecule 1b
chr11_+_6819050 0.79 ENSDART00000104289
RAB3A, member RAS oncogene family, b
chr5_+_52625975 0.78 ENSDART00000170341
ENSDART00000168317
amyloid beta (A4) precursor protein-binding, family A, member 1a
chr2_-_24462277 0.78 ENSDART00000033922
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1a
chr2_+_26240631 0.78 ENSDART00000129895
paralemmin 1b
chr6_-_40744720 0.76 ENSDART00000154916
ENSDART00000186922
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr11_-_29833698 0.76 ENSDART00000079149
X-linked Kx blood group (McLeod syndrome)
chr5_-_40190949 0.75 ENSDART00000175588
WD repeat and FYVE domain containing 3
chr2_+_24177006 0.75 ENSDART00000132582
microtubule associated protein 4 like
chr19_-_28367413 0.75 ENSDART00000079092
si:dkey-261i16.5
chr6_+_36942966 0.75 ENSDART00000028895
neuronal growth regulator 1
chr10_+_34426256 0.75 ENSDART00000102566
neurobeachin a
chr21_-_29100110 0.74 ENSDART00000142598
T cell immunoglobulin and mucin domain containing 4
chr14_+_17197132 0.74 ENSDART00000054598
reticulon 4 receptor-like 2b
chr16_-_12173399 0.73 ENSDART00000142574
calsyntenin 3
chr16_-_12173554 0.71 ENSDART00000110567
ENSDART00000155935
calsyntenin 3
chr3_+_19207176 0.71 ENSDART00000087803
relaxin 3a
chr3_-_60142530 0.71 ENSDART00000153247
si:ch211-120g10.1
chr16_-_43025885 0.70 ENSDART00000193146
ENSDART00000157302
si:dkey-7j14.5
chr9_+_38962398 0.69 ENSDART00000134294
microtubule-associated protein 2
chr19_+_6938289 0.69 ENSDART00000139122
ENSDART00000178832
flotillin 1b
chr21_-_30284404 0.69 ENSDART00000066363
zgc:175066
chr4_-_9586713 0.68 ENSDART00000145613
SH3 and multiple ankyrin repeat domains 3b
chr6_-_13187168 0.67 ENSDART00000193286
ENSDART00000188350
ENSDART00000150036
ENSDART00000149940
ADAM metallopeptidase domain 23a
chr21_+_30563115 0.66 ENSDART00000028566
si:ch211-200p22.4
chr8_-_25120231 0.65 ENSDART00000147308
adhesion molecule with Ig-like domain 1
chr2_-_40135942 0.65 ENSDART00000176951
ENSDART00000098632
ENSDART00000148563
ENSDART00000149895
eph receptor A4a
chr14_+_26796684 0.64 ENSDART00000187414
kelch-like family member 4
chr14_-_4682114 0.64 ENSDART00000014454
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 4
chr5_-_46896541 0.64 ENSDART00000133240
EGF-like repeats and discoidin I-like domains 3a
chr18_+_17428506 0.62 ENSDART00000100223
zgc:91860
chr18_-_39787040 0.62 ENSDART00000169916
Dmx-like 2
chr19_+_10396042 0.62 ENSDART00000028048
ENSDART00000151735
NECAP endocytosis associated 1
chr9_+_3388099 0.61 ENSDART00000019910
distal-less homeobox 1a
chr12_+_18578597 0.60 ENSDART00000134944
glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein, b
chr10_-_15405564 0.59 ENSDART00000020665
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr6_-_32999646 0.59 ENSDART00000159510
adenylate cyclase activating polypeptide 1b (pituitary) receptor type I
chr13_-_21701323 0.59 ENSDART00000164112
si:dkey-191g9.7
chr24_-_4973765 0.59 ENSDART00000127597
zic family member 1 (odd-paired homolog, Drosophila)
chr23_-_29505645 0.59 ENSDART00000146458
kinesin family member 1B
chr3_-_28428198 0.58 ENSDART00000151546
RNA binding fox-1 homolog 1
chr25_+_19149241 0.58 ENSDART00000184982
ENSDART00000067324
milk fat globule-EGF factor 8 protein b
chr23_-_15330168 0.57 ENSDART00000035865
ENSDART00000143635
sulfatase 2b
chr3_-_51912019 0.57 ENSDART00000149914
apoptosis-associated tyrosine kinase a
chr17_-_40397752 0.57 ENSDART00000178483

chr12_+_31729075 0.57 ENSDART00000152973
si:dkey-49c17.3
chr17_-_3986236 0.57 ENSDART00000188794
ENSDART00000160830
si:ch1073-140o9.2
chr12_-_4781801 0.57 ENSDART00000167490
ENSDART00000121718
microtubule-associated protein tau a
chr7_-_31941670 0.57 ENSDART00000180929
ENSDART00000075389
brain-derived neurotrophic factor
chr1_+_53954230 0.57 ENSDART00000037729
ENSDART00000159900
centriole, cilia and spindle-associated protein a
chr4_+_6643421 0.56 ENSDART00000099462
G protein-coupled receptor 85
chr11_-_4235811 0.56 ENSDART00000121716
si:ch211-236d3.4
chr19_+_16032383 0.56 ENSDART00000046530
RAB42, member RAS oncogene family a
chr8_-_9118958 0.56 ENSDART00000037922
solute carrier family 6 (neurotransmitter transporter), member 8
chr8_-_18582922 0.56 ENSDART00000123917
transmembrane protein 47
chr18_+_19419120 0.55 ENSDART00000025107
mitogen-activated protein kinase kinase 1
chr22_+_27090136 0.55 ENSDART00000136770
si:dkey-246e1.3
chr23_+_19594608 0.55 ENSDART00000134865
sarcolemma associated protein b
chr20_-_19590378 0.55 ENSDART00000152588
brain and acute leukemia, cytoplasmic b
chr4_+_8168514 0.54 ENSDART00000150830
ninjurin 2
chr6_+_13933464 0.54 ENSDART00000109144
protein tyrosine phosphatase, receptor type, Nb
chr10_+_34426571 0.54 ENSDART00000144529
neurobeachin a
chr25_+_10458990 0.54 ENSDART00000130354
ENSDART00000044738
RIC8 guanine nucleotide exchange factor A
chr18_-_14734678 0.53 ENSDART00000142462
teashirt zinc finger homeobox 3a
chr17_-_37474689 0.52 ENSDART00000103980
cysteine-rich protein 2
chr2_+_24177190 0.52 ENSDART00000099546
microtubule associated protein 4 like
chr23_+_16620801 0.52 ENSDART00000189859
ENSDART00000184578
syntaphilin b
chr22_+_20195280 0.52 ENSDART00000088603
ENSDART00000135692
si:dkey-110c1.7
chr13_+_1100197 0.52 ENSDART00000139560
protein phosphatase 3, regulatory subunit B, alpha a
chr14_-_49063157 0.52 ENSDART00000021260
septin 8b
chr23_-_29505463 0.51 ENSDART00000050915
kinesin family member 1B
chr7_+_48460239 0.51 ENSDART00000052113
leucine rich repeat and Ig domain containing 1b
chr13_-_32995324 0.51 ENSDART00000140542
ENSDART00000037740
potassium voltage-gated channel, subfamily F, member 1b
chr6_+_23752593 0.51 ENSDART00000164366
zgc:158654
chr14_-_26177156 0.50 ENSDART00000014149
FAT atypical cadherin 2
chr25_+_3677650 0.50 ENSDART00000154348
prion protein, related sequence 3
chr14_-_34044369 0.50 ENSDART00000149396
ENSDART00000123607
ENSDART00000190746
cytoplasmic FMR1 interacting protein 2
chr19_+_5604241 0.50 ENSDART00000011025
WAS/WASL interacting protein family, member 2b
chr15_+_37105986 0.50 ENSDART00000157762
amyloid beta (A4) precursor-like protein 1
chr3_-_28258462 0.50 ENSDART00000191573
RNA binding fox-1 homolog 1
chr1_-_40994259 0.50 ENSDART00000101562
adrenoceptor alpha 2C
chr3_-_26341959 0.50 ENSDART00000169344
ENSDART00000142878
ENSDART00000087196
zgc:153240
chr20_-_26039841 0.49 ENSDART00000179929
si:dkey-12h9.6
chr8_-_32497815 0.49 ENSDART00000122359
si:dkey-164f24.2
chr6_-_39605734 0.49 ENSDART00000044276
ENSDART00000179059
disco-interacting protein 2 homolog Bb
chr21_+_44684577 0.49 ENSDART00000099528
sprouty homolog 4 (Drosophila)
chr16_-_17162843 0.49 ENSDART00000089386
intermediate filament family orphan 1b
chr20_-_19365875 0.49 ENSDART00000063703
ENSDART00000187707
ENSDART00000161065
si:dkey-71h2.2
chr25_+_15647993 0.48 ENSDART00000186578
ENSDART00000031828
spondin 1b
chr20_+_30445971 0.48 ENSDART00000153150
myelin transcription factor 1-like, a
chr5_-_46980651 0.48 ENSDART00000181022
ENSDART00000168038
EGF-like repeats and discoidin I-like domains 3a
chr2_+_38924975 0.48 ENSDART00000109219
RAS (RAD and GEM)-like GTP binding 2
chr20_+_40457599 0.48 ENSDART00000017553
serine incorporator 1
chr18_-_8579907 0.48 ENSDART00000147284
si:ch211-220f12.1
chr15_-_22147860 0.47 ENSDART00000149784
sodium channel, voltage-gated, type III, beta
chr9_-_46072805 0.47 ENSDART00000169682
histone deacetylase 4
chr16_-_52879741 0.47 ENSDART00000166470
tubulin polymerization promoting protein
chr6_+_13787855 0.47 ENSDART00000182899
transmembrane protein 198b
chr16_+_30117798 0.47 ENSDART00000135723
ENSDART00000000198
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6E
chr7_+_36898850 0.47 ENSDART00000113342
TOX high mobility group box family member 3
chr13_+_23132666 0.46 ENSDART00000164639
sorbin and SH3 domain containing 1
chr21_-_4032650 0.46 ENSDART00000151648
netrin g2b
chr4_+_12113105 0.46 ENSDART00000182399
transmembrane protein 178B
chr7_+_7019911 0.46 ENSDART00000172421
RNA binding motif protein 14b
chr19_+_24039830 0.46 ENSDART00000100422
Ras-like without CAAX 1
chr1_-_10473630 0.46 ENSDART00000040116
trinucleotide repeat containing 5
chr8_-_32497581 0.46 ENSDART00000176298
ENSDART00000183340
si:dkey-164f24.2
chr23_+_31405497 0.46 ENSDART00000053546
SH3 domain binding glutamate-rich protein like 2
chr6_-_30658755 0.45 ENSDART00000065215
ENSDART00000181302
leucine rich adaptor protein 1
chr6_+_12006557 0.45 ENSDART00000128024
WD repeat, sterile alpha motif and U-box domain containing 1
chr19_-_7358184 0.45 ENSDART00000092379
oxidation resistance 1b
chr12_+_31729498 0.45 ENSDART00000188546
ENSDART00000182562
ENSDART00000186147
si:dkey-49c17.3
chr18_+_24922125 0.45 ENSDART00000180385
repulsive guidance molecule family member a
chr10_+_25219728 0.45 ENSDART00000193829
glutamate receptor, metabotropic 5a
chr16_+_46000956 0.45 ENSDART00000101753
ENSDART00000162393
myotubularin related protein 11
chr4_+_17280868 0.45 ENSDART00000145349
branched chain amino-acid transaminase 1, cytosolic
chr2_+_25929619 0.44 ENSDART00000137746
solute carrier family 7, member 14a
chr2_-_11662851 0.44 ENSDART00000145108
zgc:110130
chr13_-_40499296 0.44 ENSDART00000158338
Danio rerio cyclin and CBS domain divalent metal cation transport mediator 1 (cnnm1), mRNA.
chr11_+_30162407 0.44 ENSDART00000190333
ENSDART00000127502
cyclin-dependent kinase-like 5
chr13_+_1944451 0.43 ENSDART00000125914
3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1
chr9_-_44295071 0.43 ENSDART00000011837
neuronal differentiation 1
chr5_-_68495224 0.42 ENSDART00000187955
eph receptor B4a
chr5_+_52705539 0.41 ENSDART00000189436
amyloid beta (A4) precursor protein-binding, family A, member 1a
chr9_+_29603649 0.41 ENSDART00000140477
mcf.2 cell line derived transforming sequence-like b
chr2_-_30668580 0.41 ENSDART00000087270
catenin (cadherin-associated protein), delta 2b
chr17_+_31221761 0.41 ENSDART00000155580
coiled-coil domain containing 32
chr5_-_45634675 0.41 ENSDART00000168534
neuropeptide FF receptor 2a
chr11_-_36341189 0.41 ENSDART00000159752
sortilin 1a
chr13_+_32446169 0.41 ENSDART00000143325
5'-nucleotidase, cytosolic IB a
chr2_+_20472150 0.41 ENSDART00000168537
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase a
chr12_+_27704015 0.41 ENSDART00000153256
calcium channel, voltage-dependent, T type, alpha 1G subunit
chr12_+_32729470 0.40 ENSDART00000175712
RNA binding fox-1 homolog 3a
chr12_+_22404108 0.40 ENSDART00000153055
high density lipoprotein binding protein b
chr6_-_957830 0.40 ENSDART00000090019
ENSDART00000184286
zinc finger E-box binding homeobox 2b
chr3_-_6759534 0.40 ENSDART00000180862
microtubule associated serine/threonine kinase 1b
chr17_-_21278846 0.40 ENSDART00000181356
heat shock protein 12A
chr13_-_18691041 0.40 ENSDART00000057867
sideroflexin 3
chr1_+_6171585 0.40 ENSDART00000024358
protein kinase, AMP-activated, gamma 3a non-catalytic subunit
chr18_+_7286788 0.40 ENSDART00000022998
si:ch73-86n2.1
chr9_+_38163876 0.40 ENSDART00000137955
cytoplasmic linker associated protein 1a
chr15_-_18138607 0.39 ENSDART00000176690

chr17_+_25290136 0.39 ENSDART00000173295
kelch repeat and BTB (POZ) domain containing 11
chr5_-_38384289 0.39 ENSDART00000135260
misshapen-like kinase 1
chr1_+_2129164 0.39 ENSDART00000074923
ENSDART00000124534
muscleblind-like splicing regulator 2
chr13_-_49169545 0.39 ENSDART00000192076
translin-associated factor X
chr14_+_29581710 0.39 ENSDART00000188820
ENSDART00000193874
si:dkey-34l15.2
chr2_-_50372467 0.39 ENSDART00000108900
contactin associated protein like 2b
chr9_+_33154841 0.39 ENSDART00000132465
dopey family member 2
chr6_-_13408680 0.39 ENSDART00000151566
formin-like 2b
chr24_-_21989406 0.39 ENSDART00000032963
apolipoprotein O, b
chr14_-_2352384 0.38 ENSDART00000170666
si:ch73-233f7.7
chr18_-_13121983 0.38 ENSDART00000092648
ribitol xylosyltransferase 1
chr16_-_7828838 0.38 ENSDART00000191434
ENSDART00000108653
T cell activation inhibitor, mitochondrial
chr1_+_2128970 0.38 ENSDART00000180074
ENSDART00000022019
ENSDART00000098059
muscleblind-like splicing regulator 2
chr8_+_36500061 0.38 ENSDART00000185840
solute carrier family 7, member 4
chr5_-_37875636 0.38 ENSDART00000184674
Rho GTPase activating protein 35b
chr22_-_25033105 0.38 ENSDART00000124220
neuronal pentraxin receptor b
chr9_-_3149896 0.38 ENSDART00000020861
pyruvate dehydrogenase kinase, isozyme 1
chr9_+_19623363 0.38 ENSDART00000142471
ENSDART00000147662
ENSDART00000136053
pyridoxal (pyridoxine, vitamin B6) kinase a
chr13_-_11378355 0.37 ENSDART00000164566
v-akt murine thymoma viral oncogene homolog 3a
chr24_-_22756508 0.37 ENSDART00000035409
ENSDART00000146247
zinc finger, C2HC-type containing 1A
chr25_+_388258 0.37 ENSDART00000166834
regulatory factor X7b
chr7_+_20110336 0.37 ENSDART00000179395
zgc:114045
chr16_-_26437668 0.37 ENSDART00000142056
multiple EGF-like-domains 8
chr5_+_34981584 0.37 ENSDART00000134795
ankyrin repeat, family A (RFXANK-like), 2
chr1_-_10048514 0.37 ENSDART00000125358
ENSDART00000054835
ring finger protein 175
chr19_-_27261102 0.37 ENSDART00000143919
gamma-aminobutyric acid (GABA) B receptor, 1b
chr18_-_5781922 0.36 ENSDART00000128722
si:ch73-167i17.6
chr11_+_7580079 0.36 ENSDART00000091550
ENSDART00000193223
ENSDART00000193386
adhesion G protein-coupled receptor L2a
chr14_-_17599452 0.36 ENSDART00000080042
RAB33A, member RAS oncogene family
chr17_+_39790388 0.36 ENSDART00000149488
ubiquitin protein ligase E3 component n-recognin 1
chr20_+_42918755 0.36 ENSDART00000134855
EFR3 homolog Bb (S. cerevisiae)
chr4_-_16412084 0.36 ENSDART00000188460
decorin
chr24_+_19210001 0.36 ENSDART00000179373
ENSDART00000139299
zgc:162928
chr1_-_8917902 0.36 ENSDART00000137900
glutamate receptor, ionotropic, N-methyl D-aspartate 2A, b
chr9_+_2343096 0.36 ENSDART00000062292
ENSDART00000191722
ENSDART00000135180
activating transcription factor 2
chr15_+_35718354 0.36 ENSDART00000110003
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2a

Network of associatons between targets according to the STRING database.

First level regulatory network of foxb1b+foxb2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0048917 posterior lateral line ganglion development(GO:0048917)
0.3 3.1 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.3 1.0 GO:0052575 carbohydrate localization(GO:0052575) carbohydrate storage(GO:0052576)
0.3 1.8 GO:0035881 amacrine cell differentiation(GO:0035881)
0.3 0.8 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.2 0.9 GO:0099548 trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by nitric oxide(GO:0099548)
0.2 0.7 GO:1901890 positive regulation of cell junction assembly(GO:1901890)
0.2 0.6 GO:0032847 regulation of cellular pH reduction(GO:0032847) synaptic vesicle lumen acidification(GO:0097401) regulation of synaptic vesicle lumen acidification(GO:1901546)
0.2 0.6 GO:1903644 regulation of protein folding(GO:1903332) positive regulation of protein folding(GO:1903334) regulation of chaperone-mediated protein folding(GO:1903644) positive regulation of chaperone-mediated protein folding(GO:1903646)
0.1 0.4 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.1 2.1 GO:0016486 peptide hormone processing(GO:0016486)
0.1 1.1 GO:0048681 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
0.1 0.5 GO:0060300 regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.1 0.4 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
0.1 0.5 GO:0086005 ventricular cardiac muscle cell action potential(GO:0086005)
0.1 0.5 GO:0090299 regulation of neural crest formation(GO:0090299)
0.1 0.4 GO:0009098 leucine biosynthetic process(GO:0009098)
0.1 0.4 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.1 0.3 GO:0032060 bleb assembly(GO:0032060) slow muscle cell migration(GO:1904969)
0.1 0.5 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.1 0.3 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.1 0.3 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 0.9 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 0.5 GO:0021731 trigeminal motor nucleus development(GO:0021731)
0.1 0.5 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.1 0.5 GO:0023041 neuronal signal transduction(GO:0023041)
0.1 0.3 GO:0044038 cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) cellular component macromolecule biosynthetic process(GO:0070589)
0.1 0.6 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 0.4 GO:0035095 behavioral response to nicotine(GO:0035095)
0.1 0.5 GO:0099525 synaptic vesicle docking(GO:0016081) presynaptic dense core granule exocytosis(GO:0099525)
0.1 0.3 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.1 0.6 GO:0048853 cell proliferation in hindbrain(GO:0021534) forebrain morphogenesis(GO:0048853)
0.1 0.3 GO:0032790 ribosome disassembly(GO:0032790)
0.1 0.3 GO:0090155 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.1 0.6 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.1 0.2 GO:0006499 N-terminal protein myristoylation(GO:0006499) N-terminal peptidyl-glycine N-myristoylation(GO:0018008) protein myristoylation(GO:0018377)
0.1 0.1 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.1 0.2 GO:1903069 regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069)
0.1 0.4 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.1 0.4 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.4 GO:0035475 angioblast cell migration involved in selective angioblast sprouting(GO:0035475)
0.1 0.2 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
0.1 0.3 GO:1904184 regulation of pyruvate dehydrogenase activity(GO:1904182) positive regulation of pyruvate dehydrogenase activity(GO:1904184)
0.1 0.7 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.3 GO:0045448 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.1 0.3 GO:1903722 regulation of centriole elongation(GO:1903722)
0.1 0.4 GO:0097107 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.1 1.0 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.3 GO:1902915 negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.1 0.3 GO:0003232 bulbus arteriosus development(GO:0003232)
0.1 0.9 GO:1900006 positive regulation of dendrite development(GO:1900006)
0.1 0.2 GO:0061188 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.1 0.4 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 0.3 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.5 GO:0001964 startle response(GO:0001964)
0.0 0.5 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 0.7 GO:0048923 posterior lateral line neuromast hair cell differentiation(GO:0048923)
0.0 0.9 GO:0007413 axonal fasciculation(GO:0007413)
0.0 0.3 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.0 0.7 GO:0097502 protein mannosylation(GO:0035268) mannosylation(GO:0097502)
0.0 0.2 GO:0031627 telomeric loop formation(GO:0031627)
0.0 0.3 GO:0006309 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.0 1.3 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.4 GO:0021588 cerebellum formation(GO:0021588)
0.0 1.2 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 0.2 GO:0010259 multicellular organism aging(GO:0010259)
0.0 0.1 GO:0006041 glucosamine metabolic process(GO:0006041) glucosamine catabolic process(GO:0006043)
0.0 0.2 GO:0016237 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) single-organism membrane invagination(GO:1902534)
0.0 0.2 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.3 GO:0040038 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.0 0.6 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.9 GO:0006595 polyamine metabolic process(GO:0006595)
0.0 0.1 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.4 GO:0009251 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.5 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.3 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.0 1.7 GO:0021854 hypothalamus development(GO:0021854)
0.0 0.2 GO:0035093 spermatid nucleus differentiation(GO:0007289) sperm chromatin condensation(GO:0035092) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.7 GO:0007032 endosome organization(GO:0007032)
0.0 0.2 GO:0035627 ceramide transport(GO:0035627)
0.0 0.2 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 1.0 GO:0060078 regulation of postsynaptic membrane potential(GO:0060078)
0.0 0.6 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.5 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.3 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.3 GO:0071679 commissural neuron axon guidance(GO:0071679)
0.0 0.3 GO:1904103 regulation of convergent extension involved in gastrulation(GO:1904103)
0.0 0.1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.2 GO:0001839 neural plate morphogenesis(GO:0001839)
0.0 0.1 GO:0045830 histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773) regulation of isotype switching(GO:0045191) positive regulation of isotype switching(GO:0045830)
0.0 0.1 GO:0033345 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.0 0.2 GO:0045905 positive regulation of translational termination(GO:0045905)
0.0 0.8 GO:0051923 sulfation(GO:0051923)
0.0 0.2 GO:0016199 axon midline choice point recognition(GO:0016199)
0.0 0.1 GO:0030101 natural killer cell activation(GO:0030101)
0.0 0.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.2 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.0 0.4 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.4 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.0 0.3 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.4 GO:0042407 cristae formation(GO:0042407)
0.0 0.4 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.1 GO:0006531 aspartate metabolic process(GO:0006531)
0.0 0.2 GO:0021553 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.0 1.4 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.4 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0019532 oxalate transport(GO:0019532)
0.0 0.1 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.0 0.1 GO:0061010 gall bladder development(GO:0061010)
0.0 0.2 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.0 0.3 GO:0099560 synaptic membrane adhesion(GO:0099560)
0.0 0.1 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.0 0.1 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827)
0.0 0.1 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.1 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.6 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.7 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.0 0.4 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.1 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.0 0.2 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.9 GO:1902749 regulation of cell cycle G2/M phase transition(GO:1902749)
0.0 0.1 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)
0.0 0.3 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.4 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.3 GO:1901642 nucleoside transport(GO:0015858) nucleoside transmembrane transport(GO:1901642)
0.0 1.3 GO:0016358 dendrite development(GO:0016358)
0.0 0.1 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.0 0.1 GO:0030952 establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0 0.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.8 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.3 GO:0014812 muscle cell migration(GO:0014812)
0.0 0.3 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.5 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.2 GO:1901571 icosanoid transport(GO:0071715) fatty acid derivative transport(GO:1901571)
0.0 0.1 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866) positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.3 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 1.2 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.8 GO:0021954 central nervous system neuron development(GO:0021954)
0.0 0.3 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.4 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 1.6 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.2 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.0 0.1 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.1 GO:0003352 regulation of cilium movement(GO:0003352)
0.0 0.1 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.2 GO:0043462 regulation of ATPase activity(GO:0043462)
0.0 0.4 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.1 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.2 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.1 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.2 GO:0030168 platelet activation(GO:0030168)
0.0 0.1 GO:0050955 thermoception(GO:0050955) detection of temperature stimulus involved in thermoception(GO:0050960) detection of temperature stimulus involved in sensory perception(GO:0050961)
0.0 0.4 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.4 GO:1902850 mitotic spindle assembly(GO:0090307) microtubule cytoskeleton organization involved in mitosis(GO:1902850)
0.0 0.6 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.3 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.2 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.6 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 0.1 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.1 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.6 GO:0051017 actin filament bundle assembly(GO:0051017)
0.0 0.4 GO:0030901 midbrain development(GO:0030901)
0.0 0.1 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.2 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.2 GO:0015936 coenzyme A metabolic process(GO:0015936)
0.0 0.2 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.1 GO:0003272 endocardial cushion formation(GO:0003272)
0.0 0.4 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.3 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.0 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.2 0.6 GO:0072380 TRC complex(GO:0072380)
0.2 0.7 GO:0016600 flotillin complex(GO:0016600)
0.2 0.6 GO:0043291 RAVE complex(GO:0043291)
0.1 0.4 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 0.9 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.4 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 0.3 GO:0035339 SPOTS complex(GO:0035339)
0.1 1.0 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.3 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.7 GO:0098888 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.1 0.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.4 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 0.4 GO:0033010 paranodal junction(GO:0033010)
0.0 0.2 GO:0016460 myosin II complex(GO:0016460)
0.0 0.4 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.0 0.3 GO:0043194 axon initial segment(GO:0043194)
0.0 0.7 GO:0031209 SCAR complex(GO:0031209)
0.0 0.5 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.2 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.9 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.3 GO:0016586 RSC complex(GO:0016586)
0.0 0.4 GO:0061617 MICOS complex(GO:0061617)
0.0 0.1 GO:0044326 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.0 0.1 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.6 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.0 0.4 GO:1990246 uniplex complex(GO:1990246)
0.0 0.2 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 2.2 GO:0005871 kinesin complex(GO:0005871)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.8 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.5 GO:0043195 terminal bouton(GO:0043195)
0.0 0.5 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 1.1 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.2 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.5 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.7 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 0.4 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.5 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.6 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.1 GO:0030897 HOPS complex(GO:0030897)
0.0 0.6 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.1 GO:0030062 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 3.0 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.3 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 2.3 GO:0030133 transport vesicle(GO:0030133)
0.0 0.1 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.0 0.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 2.5 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.1 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.6 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.5 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.3 GO:0031105 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 6.5 GO:0043005 neuron projection(GO:0043005)
0.0 0.4 GO:0000421 autophagosome membrane(GO:0000421)
0.0 1.6 GO:0014069 postsynaptic density(GO:0014069)
0.0 0.4 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 0.8 GO:0005604 basement membrane(GO:0005604)
0.0 0.2 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.1 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.4 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.2 1.0 GO:0004645 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.2 0.5 GO:0031701 angiotensin receptor binding(GO:0031701)
0.2 2.0 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 0.9 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 1.9 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.4 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 0.4 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.1 0.3 GO:0052725 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726)
0.1 0.4 GO:0004133 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
0.1 0.9 GO:0030332 cyclin binding(GO:0030332)
0.1 0.8 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.4 GO:0005003 ephrin receptor activity(GO:0005003)
0.1 0.5 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.1 0.2 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379)
0.1 0.3 GO:0043560 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.1 0.3 GO:0030626 U12 snRNA binding(GO:0030626)
0.1 0.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 0.4 GO:0022889 serine transmembrane transporter activity(GO:0022889)
0.1 0.3 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 2.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.4 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.1 0.9 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 0.8 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.1 0.4 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 1.5 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 0.4 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.5 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.4 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.7 GO:0005165 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.1 0.2 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765) inositol trisphosphate kinase activity(GO:0051766)
0.1 0.2 GO:1902387 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.1 1.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.9 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.2 GO:0032038 myosin head/neck binding(GO:0032028) myosin II head/neck binding(GO:0032034) myosin II heavy chain binding(GO:0032038)
0.0 0.4 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.4 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.6 GO:0008503 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.4 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0 0.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.2 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.3 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.0 0.2 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.0 0.2 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.3 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.5 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.2 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.7 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.3 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.1 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.2 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.1 GO:0046592 polyamine oxidase activity(GO:0046592)
0.0 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.3 GO:0005158 insulin receptor binding(GO:0005158)
0.0 1.0 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:1990757 anaphase-promoting complex binding(GO:0010997) ubiquitin ligase activator activity(GO:1990757)
0.0 0.2 GO:0010858 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.4 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.4 GO:0030552 cAMP binding(GO:0030552)
0.0 0.1 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0 0.4 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.3 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.3 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.8 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
0.0 1.5 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.2 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.2 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.2 GO:0031420 potassium ion binding(GO:0030955) alkali metal ion binding(GO:0031420)
0.0 0.2 GO:0043495 protein anchor(GO:0043495)
0.0 0.2 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 1.1 GO:0005178 integrin binding(GO:0005178)
0.0 0.1 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.3 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.4 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.1 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.0 0.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:0047464 heparosan-N-sulfate-glucuronate 5-epimerase activity(GO:0047464)
0.0 0.3 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.3 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.4 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.0 GO:0070735 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.0 0.4 GO:0016208 AMP binding(GO:0016208)
0.0 0.2 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)
0.0 4.2 GO:0015631 tubulin binding(GO:0015631)
0.0 0.4 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.2 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 0.6 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.7 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.2 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.6 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.8 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.9 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.3 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.5 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.7 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.5 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.2 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.6 PID BMP PATHWAY BMP receptor signaling
0.0 0.4 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.5 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.1 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.2 0.8 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.0 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.1 0.6 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 0.6 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 0.6 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 0.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.4 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.4 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.1 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.4 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.2 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.1 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.2 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.5 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.1 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.1 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.5 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.1 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis