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PRJNA207719: Tissue specific transcriptome profiling

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Results for foxa3

Z-value: 1.66

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Transcription factors associated with foxa3

Gene Symbol Gene ID Gene Info
ENSDARG00000012788 forkhead box A3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxa3dr11_v1_chr18_-_46354269_463542690.306.3e-01Click!

Activity profile of foxa3 motif

Sorted Z-values of foxa3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr18_-_16795262 1.44 ENSDART00000048722
adenosine monophosphate deaminase 3b
chr13_+_22480857 1.43 ENSDART00000078721
ENSDART00000044719
ENSDART00000130957
ENSDART00000078757
ENSDART00000130424
ENSDART00000078747
LIM domain binding 3a
chr12_-_26064480 1.17 ENSDART00000158215
ENSDART00000171206
ENSDART00000171212
ENSDART00000182956
ENSDART00000186779
LIM domain binding 3b
chr3_-_43770876 1.11 ENSDART00000160162
zgc:92162
chr16_+_23978978 1.07 ENSDART00000058964
ENSDART00000135084
apolipoprotein A-II
chr23_-_21515182 1.07 ENSDART00000142000
ring finger protein 207b
chr21_-_20840714 1.07 ENSDART00000144861
ENSDART00000139430
complement component 6
chr4_-_6373735 1.06 ENSDART00000140100
si:ch73-156e19.1
chr3_-_50865079 1.03 ENSDART00000164295
peripheral myelin protein 22a
chr21_-_17296789 1.01 ENSDART00000192180
growth factor independent 1B transcription repressor
chr10_-_15128771 0.99 ENSDART00000101261
secreted phosphoprotein 1
chr18_+_35842933 0.98 ENSDART00000151587
ENSDART00000131121
protein phosphatase 1, regulatory subunit 13 like
chr18_+_20566817 0.96 ENSDART00000100716
BH3 interacting domain death agonist
chr6_-_13206255 0.96 ENSDART00000065373
eukaryotic translation elongation factor 1 beta 2
chr25_-_13188678 0.95 ENSDART00000125754
si:ch211-147m6.1
chr5_-_16351306 0.93 ENSDART00000168643

chr8_+_49570884 0.91 ENSDART00000182117
ENSDART00000108613
RAS and EF-hand domain containing
chr21_-_22951604 0.88 ENSDART00000083449
ENSDART00000180129
duboraya
chr14_-_29799993 0.86 ENSDART00000133775
ENSDART00000005568
PDZ and LIM domain 3b
chr22_-_10110959 0.85 ENSDART00000031005
ENSDART00000147580
glutaminase 2b (liver, mitochondrial)
chr2_-_36933472 0.83 ENSDART00000170405

chr14_-_4120636 0.83 ENSDART00000059230
interferon regulatory factor 2
chr24_-_26369185 0.81 ENSDART00000080039
leucine rich repeat containing 31
chr20_-_9980318 0.80 ENSDART00000080664
zgc:86709
chr5_+_22970617 0.80 ENSDART00000192859
high mobility group nucleosomal binding domain 7
chr2_+_10134345 0.80 ENSDART00000100725
alpha-2-HS-glycoprotein 2
chr6_-_8736766 0.79 ENSDART00000143956
caveolae associated protein 2b
chr3_+_13559199 0.77 ENSDART00000166547
si:ch73-106n3.1
chr7_-_5029478 0.76 ENSDART00000193819
leukotriene B4 receptor
chr2_-_32262287 0.76 ENSDART00000056621
ENSDART00000039717
family with sequence similarity 49, member Ba
chr7_-_32020100 0.75 ENSDART00000185433
kinesin family member 18A
chr21_-_25295087 0.74 ENSDART00000087910
ENSDART00000147860
suppression of tumorigenicity 14 (colon carcinoma) b
chr23_+_32044410 0.72 ENSDART00000048628
myosin light chain kinase 2
chr9_-_21912227 0.71 ENSDART00000145576
LIM domain 7a
chr22_-_36856405 0.71 ENSDART00000029588
kininogen 1
chr16_-_17713859 0.69 ENSDART00000149275
zgc:174935
chr6_+_52918537 0.68 ENSDART00000174229
odorant receptor, family H, subfamily 137, member 1
chr14_+_20893065 0.68 ENSDART00000079452
lysozyme g-like 1
chr2_-_38035235 0.67 ENSDART00000075904
cerebellin 5
chr1_+_26667872 0.67 ENSDART00000152803
ENSDART00000152144
ENSDART00000152785
ENSDART00000152393
hemogen
chr5_-_63302944 0.66 ENSDART00000047110
gelsolin b
chr21_-_35419486 0.65 ENSDART00000138529
si:dkeyp-23e4.3
chr4_-_12795436 0.64 ENSDART00000131026
ENSDART00000075127
beta-2-microglobulin
chr15_+_24644016 0.64 ENSDART00000043292
smoothelin, like
chr22_+_7497319 0.64 ENSDART00000034564
zgc:92511
chr25_+_14087045 0.63 ENSDART00000155770
actin, alpha, cardiac muscle 1c
chr23_+_26026383 0.63 ENSDART00000141553
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr8_-_43923788 0.63 ENSDART00000146152
adhesion G protein-coupled receptor D1
chr24_+_19542323 0.62 ENSDART00000140379
ENSDART00000142830
sulfatase 1
chr3_+_15828999 0.62 ENSDART00000104397
transmembrane protein 11
chr7_+_20512419 0.62 ENSDART00000173907
si:dkey-19b23.14
chr6_-_53048291 0.60 ENSDART00000103267
family with sequence similarity 212, member Ab
chr20_+_52546186 0.59 ENSDART00000110777
ENSDART00000153377
ENSDART00000153013
ENSDART00000042704
eukaryotic translation elongation factor 1 delta b (guanine nucleotide exchange protein)
chr3_+_23743139 0.58 ENSDART00000187409
homeobox B3a
chr2_+_23731194 0.58 ENSDART00000155747
solute carrier family 22 member 13a
chr25_-_30344117 0.58 ENSDART00000167077
protein disulfide isomerase family A, member 3
chr23_+_36653376 0.57 ENSDART00000053189
G protein-coupled receptor 182
chr11_-_11336986 0.56 ENSDART00000016677
zgc:77929
chr1_-_44940830 0.56 ENSDART00000097500
ENSDART00000134464
ENSDART00000137216
transmembrane protein 176
chr5_+_28830643 0.55 ENSDART00000051448
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr20_+_15015557 0.55 ENSDART00000039345
myocilin
chr11_-_183328 0.55 ENSDART00000168562
advillin
chr16_-_21785261 0.55 ENSDART00000078858
si:ch73-86n18.1
chr2_+_37875789 0.54 ENSDART00000036318
ENSDART00000127679
cerebellin 13
chr4_+_14981854 0.54 ENSDART00000067046
cation/H+ exchanger protein 1
chr2_+_30916188 0.54 ENSDART00000137012
myomesin 1a (skelemin)
chr3_+_29941777 0.54 ENSDART00000113889
interferon-induced protein 35
chr24_+_25258904 0.53 ENSDART00000155714
gamma-aminobutyric acid (GABA) A receptor, rho 3b
chr4_+_12358822 0.53 ENSDART00000172557
ENSDART00000150627
Pim proto-oncogene, serine/threonine kinase, related 168
chr5_+_36513605 0.53 ENSDART00000013590
wingless-type MMTV integration site family, member 11
chr10_+_23553533 0.53 ENSDART00000159654

chr9_-_23253870 0.53 ENSDART00000143657
ENSDART00000169911
aminocarboxymuconate semialdehyde decarboxylase
chr5_+_28797771 0.52 ENSDART00000188845
ENSDART00000149066
si:ch211-186e20.7
chr22_-_14128716 0.52 ENSDART00000140323
si:ch211-246m6.4
chr7_-_8417315 0.52 ENSDART00000173046
jacalin 1
chr8_-_19313510 0.51 ENSDART00000164780
ENSDART00000137133
ral guanine nucleotide dissociation stimulator-like 1
chr16_-_54455573 0.51 ENSDART00000075275
pyruvate kinase L/R
chr25_-_31423493 0.51 ENSDART00000027661
myogenic differentiation 1
chr4_+_1619584 0.51 ENSDART00000148486
SR-related CTD-associated factor 11
chr5_+_42092227 0.51 ENSDART00000097583
ENSDART00000171678
ubiquitin B
chr5_-_14509137 0.50 ENSDART00000180742
si:ch211-244o22.2
chr11_+_13223625 0.50 ENSDART00000161275
ATP-binding cassette, sub-family B (MDR/TAP), member 11b
chr3_+_32129632 0.50 ENSDART00000174522
zgc:109934
chr1_+_11107688 0.50 ENSDART00000109858
kinetochore-localized astrin/SPAG5 binding protein
chr7_-_20158380 0.50 ENSDART00000142891
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr13_-_36761379 0.49 ENSDART00000131534
ENSDART00000029824
mitogen-activated protein kinase kinase kinase kinase 5
chr25_-_13188214 0.49 ENSDART00000187298
si:ch211-147m6.1
chr1_+_1805294 0.49 ENSDART00000103850
ATPase Na+/K+ transporting subunit alpha 1a, tandem duplicate 3
chr11_-_30634286 0.49 ENSDART00000191019
zgc:153665
chr4_-_12795030 0.49 ENSDART00000150427
beta-2-microglobulin
chr1_+_9153141 0.49 ENSDART00000081343
polo-like kinase 1 (Drosophila)
chr5_+_28857969 0.49 ENSDART00000149850
si:ch211-186e20.2
chr17_-_23709347 0.48 ENSDART00000124661
3'-phosphoadenosine 5'-phosphosulfate synthase 2a
chr3_-_41292569 0.47 ENSDART00000111856
sidekick cell adhesion molecule 1a
chr6_-_38930726 0.47 ENSDART00000154151
histone deacetylase 7b
chr17_+_33418475 0.47 ENSDART00000169145
synaptosomal-associated protein 23.1
chr20_-_1383916 0.47 ENSDART00000152373
scavenger receptor class A, member 5 (putative)
chr20_+_6142433 0.47 ENSDART00000054084
ENSDART00000136986
transthyretin (prealbumin, amyloidosis type I)
chr5_+_28830388 0.46 ENSDART00000149150
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr23_-_21215311 0.46 ENSDART00000112424
multiple EGF-like-domains 6a
chr16_-_13992646 0.46 ENSDART00000139623
si:dkey-85k15.6
chr7_+_34305903 0.46 ENSDART00000173575
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr13_-_36844945 0.46 ENSDART00000129562
ENSDART00000150899
ninein (GSK3B interacting protein)
chr3_-_41292275 0.46 ENSDART00000144088
sidekick cell adhesion molecule 1a
chr24_-_31306724 0.46 ENSDART00000165399
acid phosphatase 5b, tartrate resistant
chr14_-_6931889 0.45 ENSDART00000166439
si:ch211-266k2.1
chr14_-_36799280 0.43 ENSDART00000168615
ring finger protein 130
chr4_-_16334362 0.43 ENSDART00000101461
epiphycan
chr20_+_51104367 0.43 ENSDART00000073981
eukaryotic translation initiation factor 2, subunit 1 alpha b
chr24_-_26485098 0.43 ENSDART00000135496
ENSDART00000009609
ENSDART00000133782
ENSDART00000141029
ENSDART00000113739
eukaryotic translation initiation factor 5A
chr5_+_29726428 0.43 ENSDART00000143183
DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
chr2_+_38161318 0.42 ENSDART00000044264
matrix metallopeptidase 14b (membrane-inserted)
chr15_-_25571865 0.42 ENSDART00000077836
matrix metallopeptidase 20b (enamelysin)
chr17_+_8799661 0.42 ENSDART00000105326
tonsoku-like, DNA repair protein
chr2_+_20539402 0.42 ENSDART00000129585
si:ch73-14h1.2
chr8_+_39795918 0.42 ENSDART00000143413
si:ch211-170d8.2
chr5_-_54712159 0.41 ENSDART00000149207
cyclin B1
chr5_-_66160415 0.41 ENSDART00000073895
membrane bound O-acyltransferase domain containing 4
chr1_+_37391716 0.41 ENSDART00000191986
SPARC-like 1
chr7_+_58730201 0.41 ENSDART00000073640
pleiomorphic adenoma gene 1
chr3_+_52442102 0.41 ENSDART00000155455
si:ch211-191c10.1
chr3_+_12744083 0.41 ENSDART00000158554
ENSDART00000169545
cytochrome P450, family 2, subfamily k, polypeptide 21
chr15_-_26552393 0.41 ENSDART00000150152
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2b
chr17_-_53439866 0.40 ENSDART00000154826
c-myc binding protein
chr23_+_42813415 0.40 ENSDART00000055577
myosin, light chain 9a, regulatory
chr2_+_24936766 0.40 ENSDART00000025962
glycogenin 1a
chr15_-_44052927 0.40 ENSDART00000166209
wu:fb44b02
chr17_+_30843881 0.40 ENSDART00000149600
ENSDART00000148547
tripeptidyl peptidase I
chr6_-_25384526 0.40 ENSDART00000160544
zgc:153916
chr4_-_30055196 0.39 ENSDART00000139539
si:rp71-7l19.2
chr17_-_42988356 0.39 ENSDART00000024558
zgc:92137
chr12_-_29301022 0.39 ENSDART00000187826
SH2 domain containing 4Bb
chr1_-_58009216 0.39 ENSDART00000143829
nucleoredoxin like 1
chr15_-_37719679 0.38 ENSDART00000184025
si:dkey-117a8.1
chr22_+_6905210 0.38 ENSDART00000167530

chr21_-_26490186 0.38 ENSDART00000009889
zgc:110540
chr3_+_12484008 0.38 ENSDART00000182229
vasorin b
chr11_+_2391649 0.38 ENSDART00000104571
insulin-like growth factor binding protein 6a
chr2_-_36597793 0.38 ENSDART00000113397
T-cell receptor alpha/delta variable 30.0.6
chr10_+_15603082 0.38 ENSDART00000024450
zinc finger, AN1-type domain 5b
chr2_-_57264262 0.37 ENSDART00000183815
ENSDART00000149829
ENSDART00000088508
ENSDART00000149508
methyl-CpG binding domain protein 3a
chr17_+_24036791 0.37 ENSDART00000140767
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2b
chr16_-_25233515 0.37 ENSDART00000058943
zgc:110182
chr3_-_56871330 0.37 ENSDART00000014103
zgc:112148
chr5_+_28849155 0.36 ENSDART00000079090
zgc:174259
chr16_+_23913943 0.36 ENSDART00000175404
ENSDART00000129525
apolipoprotein A-IV b, tandem duplicate 1
chr23_-_29357764 0.36 ENSDART00000156512
si:ch211-129o18.4
chr19_+_7636941 0.36 ENSDART00000081611
ENSDART00000163805
ENSDART00000112404
cingulin b
chr21_-_21020708 0.36 ENSDART00000064032
eukaryotic translation initiation factor 4E binding protein 1
chr8_+_30456161 0.35 ENSDART00000085894
phosphoglucomutase 5
chr5_+_37068223 0.35 ENSDART00000164279
si:dkeyp-110c7.4
chr15_+_14856307 0.35 ENSDART00000167213
diablo, IAP-binding mitochondrial protein a
chr5_+_28848870 0.35 ENSDART00000149563
zgc:174259
chr9_-_34396264 0.35 ENSDART00000045754
growth hormone regulated TBC protein 1b
chr11_+_2391469 0.35 ENSDART00000182121
insulin-like growth factor binding protein 6a
chr4_-_1824836 0.35 ENSDART00000111858
mitochondrial ribosomal protein L42
chr8_+_30780985 0.35 ENSDART00000193971
ENSDART00000111533
taste receptor, type 2, member 200, tandem duplicate 2
chr5_+_32345187 0.35 ENSDART00000147132
complement component 9
chr15_-_29586747 0.35 ENSDART00000076749
SAM domain, SH3 domain and nuclear localisation signals 1a
chr16_-_35952789 0.34 ENSDART00000180118
eva-1 homolog Ba (C. elegans)
chr22_-_24285432 0.34 ENSDART00000164083
si:ch211-117l17.4
chr7_-_51300277 0.34 ENSDART00000174174
guanylyl cyclase 2
chr25_-_35101673 0.34 ENSDART00000140864
zgc:162611
chr3_+_15828426 0.34 ENSDART00000135299
transmembrane protein 11
chr25_-_35101396 0.34 ENSDART00000138865
zgc:162611
chr11_-_25539323 0.34 ENSDART00000155785
si:dkey-245f22.3
chr7_+_4682659 0.34 ENSDART00000112697
si:ch211-225k7.2
chr3_-_6719232 0.34 ENSDART00000154294
autophagy related 4D, cysteine peptidase b
chr3_+_2719243 0.33 ENSDART00000189256

chr3_+_32571929 0.33 ENSDART00000151025
si:ch73-248e21.1
chr21_-_1625976 0.32 ENSDART00000066621
vitelline membrane outer layer 1 homolog b
chr11_-_7380674 0.32 ENSDART00000014979
ENSDART00000103418
vitellogenin 3, phosvitinless
chr13_+_6295336 0.32 ENSDART00000172098
angiopoietin 2a
chr7_-_18545515 0.32 ENSDART00000040534
regulator of G protein signaling 12a
chr3_-_10739625 0.31 ENSDART00000156144
zgc:112965
chr5_+_28858345 0.31 ENSDART00000111180
si:ch211-186e20.2
chr9_-_456541 0.31 ENSDART00000159596
zgc:91849
chr9_-_44948488 0.31 ENSDART00000059228
villin 1
chr17_+_43843536 0.31 ENSDART00000164097

chr3_-_1364946 0.31 ENSDART00000159328

chr16_+_11724230 0.31 ENSDART00000060266
carcinoembryonic antigen-related cell adhesion molecule 1
chr5_-_20194876 0.31 ENSDART00000122587
D-amino-acid oxidase, tandem duplicate 1
chr7_+_19850889 0.31 ENSDART00000100782
MUS81 structure-specific endonuclease subunit
chr2_-_5475910 0.31 ENSDART00000100954
ENSDART00000172143
ENSDART00000132496
protein C (inactivator of coagulation factors Va and VIIIa), a
protein C (inactivator of coagulation factors Va and VIIIa), a
chr5_-_23485161 0.31 ENSDART00000170293
ENSDART00000134069
si:dkeyp-20g2.1
si:dkeyp-20g2.3
chr24_+_20575259 0.30 ENSDART00000010488
kelch-like family member 40b
chr14_+_32918484 0.30 ENSDART00000105721
ligand of numb-protein X 2b
chr13_-_16066997 0.30 ENSDART00000184790
spermatogenesis associated 48
chr3_-_23470986 0.29 ENSDART00000113135
male-specific lethal 1 homolog a (Drosophila)
chr8_-_3312384 0.29 ENSDART00000035965
fucosyltransferase 9b
chr1_+_12068800 0.29 ENSDART00000055566
xeroderma pigmentosum, complementation group A
chr2_+_25839940 0.29 ENSDART00000139927
eukaryotic translation initiation factor 5A2
chr2_-_22569488 0.29 ENSDART00000158608

chr7_-_58729894 0.28 ENSDART00000149347
coiled-coil-helix-coiled-coil-helix domain containing 7
chr16_+_20904754 0.28 ENSDART00000006043
homeobox A11b
chr13_+_42544009 0.28 ENSDART00000145409
si:dkey-221j11.3
chr18_+_33550667 0.28 ENSDART00000141246
ENSDART00000136070
si:dkey-47k20.1
chr7_-_17570923 0.28 ENSDART00000188476
ENSDART00000080624
novel immune-type receptor 5
chr15_-_26552652 0.28 ENSDART00000152336
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2b
chr16_-_30564319 0.27 ENSDART00000145087
lamin A

Network of associatons between targets according to the STRING database.

First level regulatory network of foxa3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.3 1.0 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.3 0.9 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341)
0.2 0.7 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.2 0.5 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.2 0.5 GO:0034036 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.1 0.5 GO:0048014 Tie signaling pathway(GO:0048014)
0.1 0.5 GO:0015722 canalicular bile acid transport(GO:0015722) bile acid secretion(GO:0032782)
0.1 0.9 GO:0045901 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.1 0.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.8 GO:0006537 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.1 1.4 GO:0032264 IMP salvage(GO:0032264)
0.1 0.7 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.1 0.3 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.1 0.5 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.1 0.3 GO:1901255 UV-damage excision repair(GO:0070914) nucleotide-excision repair involved in interstrand cross-link repair(GO:1901255)
0.1 0.5 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.1 0.3 GO:0010359 regulation of anion channel activity(GO:0010359)
0.1 0.5 GO:0019805 quinolinate biosynthetic process(GO:0019805) quinolinate metabolic process(GO:0046874)
0.1 1.1 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.1 0.5 GO:0035176 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.1 0.4 GO:0097186 amelogenesis(GO:0097186)
0.1 1.1 GO:0032309 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.1 0.6 GO:2000290 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.1 0.3 GO:2000392 lamellipodium morphogenesis(GO:0072673) regulation of lamellipodium morphogenesis(GO:2000392)
0.1 0.3 GO:0006524 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.1 0.3 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.1 0.5 GO:0034755 iron ion transmembrane transport(GO:0034755) protein homotrimerization(GO:0070207)
0.1 0.5 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 0.7 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 0.2 GO:1903232 melanosome assembly(GO:1903232)
0.1 0.2 GO:0044821 telomere localization(GO:0034397) telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic telomere clustering(GO:0045141) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 0.2 GO:0042590 antigen processing and presentation of exogenous peptide antigen(GO:0002478) antigen processing and presentation of exogenous antigen(GO:0019884) antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.1 0.3 GO:0090342 regulation of cell aging(GO:0090342)
0.1 4.5 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.1 0.2 GO:1900364 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.1 1.4 GO:0051014 actin filament severing(GO:0051014)
0.1 0.2 GO:0002407 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0 0.4 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.7 GO:0032094 response to food(GO:0032094)
0.0 0.4 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.2 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.3 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.2 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.5 GO:0035306 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0 0.5 GO:0045453 bone resorption(GO:0045453)
0.0 0.4 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 1.1 GO:0019835 cytolysis(GO:0019835)
0.0 0.5 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.3 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.1 GO:0042304 regulation of fatty acid biosynthetic process(GO:0042304)
0.0 0.0 GO:1903537 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.0 1.0 GO:0007007 inner mitochondrial membrane organization(GO:0007007)
0.0 0.1 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.0 0.5 GO:0001952 regulation of cell-matrix adhesion(GO:0001952)
0.0 0.3 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.4 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.1 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.3 GO:0072498 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573) embryonic skeletal joint development(GO:0072498)
0.0 1.5 GO:0006414 translational elongation(GO:0006414)
0.0 0.3 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.4 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.5 GO:0036376 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.3 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.1 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.2 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.1 GO:0002369 T cell cytokine production(GO:0002369)
0.0 0.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.1 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.2 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.4 GO:0031297 replication fork processing(GO:0031297)
0.0 0.4 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.3 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.5 GO:0034112 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.0 0.1 GO:0009146 dGTP catabolic process(GO:0006203) purine nucleoside triphosphate catabolic process(GO:0009146) purine deoxyribonucleoside triphosphate catabolic process(GO:0009217) dGTP metabolic process(GO:0046070)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)
0.0 1.6 GO:0055113 epiboly involved in gastrulation with mouth forming second(GO:0055113)
0.0 0.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.9 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.2 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.0 0.1 GO:1901099 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.2 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.4 GO:2001236 regulation of extrinsic apoptotic signaling pathway(GO:2001236)
0.0 0.1 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.2 GO:0045667 regulation of osteoblast differentiation(GO:0045667)
0.0 0.0 GO:0019323 pentose catabolic process(GO:0019323)
0.0 0.9 GO:0010842 retina layer formation(GO:0010842)
0.0 0.5 GO:0060037 pharyngeal system development(GO:0060037)
0.0 0.1 GO:0061709 reticulophagy(GO:0061709)
0.0 0.4 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 1.0 GO:0060348 bone development(GO:0060348)
0.0 0.4 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.1 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 1.0 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.3 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.0 GO:0046048 pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048)
0.0 0.1 GO:1901825 tetraterpenoid metabolic process(GO:0016108) tetraterpenoid biosynthetic process(GO:0016109) carotenoid metabolic process(GO:0016116) carotenoid biosynthetic process(GO:0016117) xanthophyll metabolic process(GO:0016122) xanthophyll biosynthetic process(GO:0016123) zeaxanthin metabolic process(GO:1901825) zeaxanthin biosynthetic process(GO:1901827)
0.0 0.2 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.4 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.3 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.0 GO:0034375 high-density lipoprotein particle remodeling(GO:0034375)
0.0 0.3 GO:0016082 synaptic vesicle priming(GO:0016082)
0.0 0.2 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.2 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.3 GO:0032355 response to estradiol(GO:0032355)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.2 1.1 GO:0042612 MHC class I protein complex(GO:0042612)
0.2 0.7 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.2 0.6 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.1 0.4 GO:0043614 multi-eIF complex(GO:0043614)
0.1 0.4 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.1 0.3 GO:0044216 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217) other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.1 3.5 GO:0031941 filamentous actin(GO:0031941)
0.1 0.3 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.1 1.1 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.2 GO:0042709 succinate-CoA ligase complex(GO:0042709)
0.1 0.3 GO:0032433 filopodium tip(GO:0032433)
0.1 0.2 GO:0031085 BLOC-3 complex(GO:0031085)
0.1 0.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 0.3 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.5 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.5 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.3 GO:0072487 MSL complex(GO:0072487)
0.0 0.2 GO:0070390 transcription export complex 2(GO:0070390)
0.0 0.1 GO:0043202 vacuolar lumen(GO:0005775) lysosomal lumen(GO:0043202)
0.0 0.8 GO:0031672 A band(GO:0031672)
0.0 0.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.7 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.8 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 1.0 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.1 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.9 GO:0005643 nuclear pore(GO:0005643)
0.0 0.1 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.6 GO:0030496 midbody(GO:0030496)
0.0 0.1 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.1 GO:0033061 DNA recombinase mediator complex(GO:0033061)
0.0 0.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.5 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.2 0.7 GO:0003796 lysozyme activity(GO:0003796)
0.2 0.5 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.2 0.5 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 0.5 GO:0015369 calcium:proton antiporter activity(GO:0015369) metal ion:proton antiporter activity(GO:0051139)
0.1 1.4 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.5 GO:0015126 canalicular bile acid transmembrane transporter activity(GO:0015126) bile acid-exporting ATPase activity(GO:0015432)
0.1 0.5 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 0.8 GO:0004974 leukotriene receptor activity(GO:0004974)
0.1 1.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 0.8 GO:0004359 glutaminase activity(GO:0004359)
0.1 0.5 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.3 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.1 0.5 GO:0004962 endothelin receptor activity(GO:0004962)
0.1 0.5 GO:0070888 E-box binding(GO:0070888)
0.1 1.1 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 0.2 GO:0004775 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775) succinate-CoA ligase (GDP-forming) activity(GO:0004776)
0.1 0.3 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity(GO:0008442)
0.1 0.7 GO:0031995 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.1 0.4 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 0.5 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 0.7 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.4 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 2.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.4 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.5 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.3 GO:0045735 nutrient reservoir activity(GO:0045735)
0.0 0.6 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.8 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 1.5 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.6 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.5 GO:0031386 protein tag(GO:0031386)
0.0 1.7 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.1 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.0 3.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.4 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.1 GO:0047291 lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.0 0.1 GO:0033897 ribonuclease T2 activity(GO:0033897)
0.0 0.4 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.3 GO:0048256 flap endonuclease activity(GO:0048256)
0.0 0.3 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.4 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.7 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.2 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.1 GO:0052885 retinol isomerase activity(GO:0050251) all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity(GO:0052885)
0.0 0.4 GO:0005518 collagen binding(GO:0005518)
0.0 0.4 GO:0043022 ribosome binding(GO:0043022)
0.0 0.5 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 0.7 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 1.1 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.7 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.0 PID FOXO PATHWAY FoxO family signaling
0.0 0.5 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.5 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.6 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.1 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.4 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 1.1 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 0.8 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.1 1.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 1.5 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 0.9 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 1.4 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.7 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.4 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.6 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.9 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.5 REACTOME KINESINS Genes involved in Kinesins
0.0 0.5 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.1 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.3 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.1 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling