Project

PRJNA207719: Tissue specific transcriptome profiling

Navigation
Downloads

Results for fosaa+fosab+fosl1a

Z-value: 1.62

Motif logo

Transcription factors associated with fosaa+fosab+fosl1a

Gene Symbol Gene ID Gene Info
ENSDARG00000015355 FOS-like antigen 1a
ENSDARG00000031683 v-fos FBJ murine osteosarcoma viral oncogene homolog Ab
ENSDARG00000040135 v-fos FBJ murine osteosarcoma viral oncogene homolog Aa

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
fosabdr11_v1_chr20_-_46554440_465544400.286.5e-01Click!
fosl1adr11_v1_chr14_-_30747686_30747686-0.029.7e-01Click!
fosaadr11_v1_chr17_-_50233493_50233493-0.019.8e-01Click!

Activity profile of fosaa+fosab+fosl1a motif

Sorted Z-values of fosaa+fosab+fosl1a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_6514962 0.99 ENSDART00000163514
DnaJ (Hsp40) homolog, subfamily C, member 5 gamma b
chr3_-_25377163 0.72 ENSDART00000055490
karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
chr16_+_26012569 0.63 ENSDART00000148846
protease, serine, 59, tandem duplicate 1
chr17_+_20923691 0.58 ENSDART00000122407
cyclin-dependent kinase 1
chr7_+_34794829 0.58 ENSDART00000009698
ENSDART00000075089
ENSDART00000173456
epithelial splicing regulatory protein 2
chr6_-_55297274 0.57 ENSDART00000184283
ubiquitin-conjugating enzyme E2C
chr20_-_2641233 0.54 ENSDART00000145335
ENSDART00000133121
BUB1 mitotic checkpoint serine/threonine kinase
chr21_-_5077715 0.50 ENSDART00000081954
HAUS augmin-like complex, subunit 1
chr6_+_56147812 0.50 ENSDART00000150219
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr11_+_29537756 0.49 ENSDART00000103388
wu:fi42e03
chr19_-_5345930 0.49 ENSDART00000066620
ENSDART00000151398
keratin type 1 c19e
chr2_+_15612755 0.46 ENSDART00000003035
amylase, alpha 2A (pancreatic)
chr3_+_1167026 0.43 ENSDART00000031823
ENSDART00000155340
TRIO and F-actin binding protein b
chr7_-_22981796 0.43 ENSDART00000167565
si:dkey-171c9.3
chr8_+_999421 0.43 ENSDART00000149528
fatty acid binding protein 1b, tandem duplicate 1
chr15_+_46329149 0.43 ENSDART00000128404
si:ch1073-340i21.3
chr10_-_25699454 0.42 ENSDART00000064376
superoxide dismutase 1, soluble
chr19_+_791538 0.41 ENSDART00000146554
ENSDART00000138406
transmembrane protein 79a
chr15_+_963292 0.41 ENSDART00000156586
arachidonate 5-lipoxygenase b, tandem duplicate 2
chr9_+_48007081 0.40 ENSDART00000060593
ENSDART00000099835
zgc:92380
chr14_-_12071679 0.39 ENSDART00000165581
thymosin beta 1
chr14_-_12071447 0.39 ENSDART00000166116
thymosin beta 1
chr3_-_49514874 0.39 ENSDART00000167179
anti-silencing function 1Ba histone chaperone
chr8_-_52715911 0.38 ENSDART00000168241
tubulin, beta 2b
chr8_+_1009831 0.38 ENSDART00000172414
fatty acid binding protein 1b, liver, tandem duplicate 2
chr15_+_46357080 0.38 ENSDART00000155571
ENSDART00000156541
wu:fb18f06
chr7_-_2163361 0.37 ENSDART00000173654
si:cabz01007812.1
chr6_+_102506 0.37 ENSDART00000172678
low density lipoprotein receptor b
chr3_-_336299 0.37 ENSDART00000105021
major histocompatibility complex class I ZFA
chr14_+_45559268 0.37 ENSDART00000173152
zgc:154040
chr14_-_246342 0.37 ENSDART00000054823
aurora kinase B
chr1_-_45177373 0.37 ENSDART00000143142
ENSDART00000034549
zgc:111983
chr3_-_32965848 0.36 ENSDART00000050930
caspase 6, apoptosis-related cysteine peptidase
chr1_-_43905252 0.36 ENSDART00000135477
ENSDART00000132089
si:dkey-22i16.3
chr5_+_39087364 0.35 ENSDART00000004286
annexin A3a
chr3_+_12554801 0.35 ENSDART00000167177
cyclin F
chr25_+_10416583 0.35 ENSDART00000073907
ets homologous factor
chr17_+_19481049 0.35 ENSDART00000024194
kinesin family member 11
chr16_-_46660680 0.34 ENSDART00000159209
ENSDART00000191929
transmembrane protein 176l.4
chr1_-_54706039 0.33 ENSDART00000083633
exosome component 1
chr25_+_37446861 0.33 ENSDART00000189250

chr5_+_1493767 0.33 ENSDART00000022132
HAUS augmin-like complex, subunit 4
chr11_+_45153104 0.33 ENSDART00000159204
ENSDART00000177585
thymidine kinase 1, soluble
chr3_-_24681404 0.33 ENSDART00000161612

chr8_-_1219815 0.32 ENSDART00000016800
ENSDART00000149969
zinc finger protein 367
chr15_+_46356879 0.32 ENSDART00000154388
wu:fb18f06
chr12_-_17655683 0.32 ENSDART00000066411
discs, large (Drosophila) homolog-associated protein 5
chr10_+_39283985 0.31 ENSDART00000016464
decapping enzyme, scavenger
chr21_+_45316330 0.31 ENSDART00000056474
ENSDART00000149314
ENSDART00000149272
ENSDART00000149156
ENSDART00000099497
transcription factor 7
chr24_+_10027902 0.31 ENSDART00000175961
ENSDART00000172773
si:ch211-146l10.8
chr2_+_49457626 0.31 ENSDART00000129967
SH3-domain GRB2-like 1a
chr12_+_10706772 0.31 ENSDART00000158227
DNA topoisomerase II alpha
chr8_+_44358443 0.30 ENSDART00000189130
ENSDART00000189212

chr2_+_49457449 0.30 ENSDART00000185470
SH3-domain GRB2-like 1a
chr1_-_48933 0.30 ENSDART00000171162
immunoglobulin-like domain containing receptor 1a
chr22_+_32228882 0.30 ENSDART00000092082
mesencephalic astrocyte-derived neurotrophic factor
chr3_-_62403550 0.30 ENSDART00000055055
SRY (sex determining region Y)-box 8b
chr4_-_58964138 0.30 ENSDART00000150259
si:ch211-64i20.3
chr8_+_6576940 0.29 ENSDART00000138135
V-set and immunoglobulin domain containing 8b
chr5_+_32791245 0.29 ENSDART00000077189
immediate early response 5-like
chr3_+_11548516 0.29 ENSDART00000059117
monocyte to macrophage differentiation-associated
chr21_-_11834452 0.29 ENSDART00000081652
Rieske (Fe-S) domain containing
chr19_+_6990970 0.29 ENSDART00000158758
ENSDART00000160482
ENSDART00000193566
kinesin family member C1
chr13_-_45155792 0.29 ENSDART00000163556
runt-related transcription factor 3
chr16_-_12060770 0.28 ENSDART00000183237
ENSDART00000103948
si:ch211-69g19.2
chr17_+_26965351 0.28 ENSDART00000114215
ENSDART00000147192
grainyhead-like transcription factor 3
chr1_-_33647138 0.28 ENSDART00000142111
ENSDART00000015547
claudin g
chr10_+_39084354 0.28 ENSDART00000158245
si:ch73-1a9.3
chr21_-_26490186 0.28 ENSDART00000009889
zgc:110540
chr12_-_49151326 0.28 ENSDART00000153244
BUB3 mitotic checkpoint protein
chr8_+_3379815 0.28 ENSDART00000155995
zgc:136963
chr5_-_30535327 0.27 ENSDART00000040328
H2A histone family, member X
chr1_+_54069450 0.27 ENSDART00000108601
ENSDART00000187878
DDB1 and CUL4 associated factor 15
chr10_+_6010570 0.27 ENSDART00000190025
ENSDART00000163680
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr23_+_2669 0.27 ENSDART00000011146
twist3
chr21_+_27340682 0.27 ENSDART00000011305
dipeptidyl-peptidase 3
chr7_+_30626378 0.27 ENSDART00000173533
ENSDART00000052541
cyclin B2
chr5_-_54712159 0.27 ENSDART00000149207
cyclin B1
chr3_-_45778123 0.27 ENSDART00000146211
H3 histone, family 3B.1
chr18_+_46151505 0.27 ENSDART00000015034
ENSDART00000141287
biliverdin reductase B
chr3_+_31680592 0.26 ENSDART00000172456
myosin, light chain kinase 5
chr20_-_30931139 0.26 ENSDART00000006778
ENSDART00000146376
acetyl-CoA acetyltransferase 2
chr23_+_26733232 0.26 ENSDART00000035080
zgc:158263
chr1_+_12348213 0.26 ENSDART00000144920
ENSDART00000138759
ENSDART00000067082
clathrin, light chain A
chr20_+_2589414 0.26 ENSDART00000043626
interleukin 20 receptor, alpha
chr20_-_29498178 0.25 ENSDART00000152986
ENSDART00000027851
ENSDART00000152954
ribonucleotide reductase M2 polypeptide
chr5_+_13647288 0.25 ENSDART00000099660
ENSDART00000139199
H2A histone family, member Va
chr6_-_426041 0.25 ENSDART00000162789
family with sequence similarity 83, member Fb
chr16_-_12060488 0.25 ENSDART00000188733
si:ch211-69g19.2
chr5_-_33022014 0.25 ENSDART00000061149
zgc:55461
chr6_-_34958274 0.25 ENSDART00000113097
hydroxysteroid (17-beta) dehydrogenase 7
chr7_+_22982201 0.25 ENSDART00000134116
cyclin B3
chr5_-_36948586 0.25 ENSDART00000193606
H3 histone, family 3C
chr25_+_5012791 0.24 ENSDART00000156970
si:ch73-265h17.5
chr16_-_13680692 0.24 ENSDART00000047452
ubiquitin-conjugating enzyme E2S
chr1_+_58840889 0.23 ENSDART00000098308
transmembrane p24 trafficking protein 1b
chr23_+_44883805 0.23 ENSDART00000182805
si:ch73-361h17.1
chr10_-_39283883 0.23 ENSDART00000023831
cryptochrome circadian clock 5
chr13_-_2010191 0.23 ENSDART00000161021
ENSDART00000124134
GDNF family receptor alpha like
chr23_+_32028574 0.23 ENSDART00000145501
ENSDART00000143121
ENSDART00000111877
TPX2, microtubule-associated, homolog (Xenopus laevis)
chr13_+_2394534 0.23 ENSDART00000172535
ENSDART00000006990
ELOVL fatty acid elongase 5
chr1_-_45157243 0.23 ENSDART00000131882
mucin, multiple PTS and SEA group, member 1
chr8_+_16758304 0.23 ENSDART00000133514
ELOVL fatty acid elongase 7a
chr3_+_17951790 0.23 ENSDART00000164663
ATP citrate lyase a
chr6_-_10927766 0.23 ENSDART00000134327
chemokine (C-C motif) receptor 7
chr18_+_5490668 0.23 ENSDART00000167035
muscle-specific beta 1 integrin binding protein 2
chr7_+_22981909 0.23 ENSDART00000122449
cyclin B3
chr13_+_2394264 0.23 ENSDART00000168595
ELOVL fatty acid elongase 5
chr9_+_41218967 0.22 ENSDART00000000280
ENSDART00000145674
signal transducer and activator of transcription 1b
chr14_-_14566417 0.22 ENSDART00000159056
si:dkey-27i16.2
chr9_-_1604601 0.22 ENSDART00000143130
alkylglycerone phosphate synthase
chr14_-_14659023 0.22 ENSDART00000170355
ENSDART00000159888
ENSDART00000172241
NAD(P) dependent steroid dehydrogenase-like
chr6_-_50704689 0.22 ENSDART00000074100
oxidative stress induced growth inhibitor 1
chr2_+_105748 0.22 ENSDART00000169601

chr19_-_617246 0.22 ENSDART00000062551
cytochrome P450, family 51
chr21_+_244503 0.22 ENSDART00000162889
StAR-related lipid transfer (START) domain containing 4
chr12_+_46543572 0.22 ENSDART00000167510
HID1 domain containing b
chr7_+_66565930 0.22 ENSDART00000154597
transmembrane protein 176l.3b
chr24_-_27473771 0.22 ENSDART00000139874
CX chemokine ligand 34b, duplicate 11
chr22_-_13042992 0.22 ENSDART00000028787
aryl hydrocarbon receptor 1b
chr24_+_17334682 0.22 ENSDART00000018868
protein disulfide isomerase family A, member 4
chr13_+_46941930 0.22 ENSDART00000056962
F-box protein 5
chr4_+_38550788 0.22 ENSDART00000157412
si:ch211-209n20.1
chr9_-_30247961 0.22 ENSDART00000131519
si:dkey-100n23.3
chr22_-_4769140 0.22 ENSDART00000165235
calreticulin 3a
chr1_+_58977262 0.22 ENSDART00000168832
ERI1 exoribonuclease family member 2
chr20_+_16743056 0.22 ENSDART00000050308
calmodulin 1b
chr6_-_25952848 0.22 ENSDART00000076997
ENSDART00000148748
LIM domain only 4b
chr22_-_10539180 0.22 ENSDART00000131217
inositol 1,3,4,5,6-pentakisphosphate 2-kinase
chr21_-_41147818 0.22 ENSDART00000167339
ENSDART00000192730
muscle segment homeobox 2b
chr8_-_49766205 0.22 ENSDART00000137941
ENSDART00000097919
ENSDART00000147309
heterogeneous nuclear ribonucleoprotein K
chr20_-_26822522 0.21 ENSDART00000146326
ENSDART00000046764
ENSDART00000103234
ENSDART00000143267
GDP-mannose 4,6-dehydratase
chr7_-_8602864 0.21 ENSDART00000173291
jacalin 2
chr8_+_8671229 0.21 ENSDART00000131963
ubiquitin specific peptidase 11
chr25_+_5983430 0.21 ENSDART00000074814
peptidylprolyl isomerase B (cyclophilin B)
chr2_-_24348948 0.21 ENSDART00000136559
anoctamin 8a
chr21_+_26733529 0.21 ENSDART00000168379
pyruvate carboxylase a
chr10_+_29816681 0.21 ENSDART00000100022
H2A histone family member X1
chr15_-_44052927 0.21 ENSDART00000166209
wu:fb44b02
chr7_-_18617187 0.21 ENSDART00000172419
si:ch211-119e14.1
chr10_+_15088534 0.21 ENSDART00000142865
si:ch211-95j8.3
chr22_-_34979139 0.21 ENSDART00000116455
ENSDART00000133537
Rho GTPase activating protein 19
chr22_-_35194187 0.21 ENSDART00000164443
ENSDART00000104687
profilin 2
chr13_-_45201300 0.21 ENSDART00000074750
ENSDART00000180265
runt-related transcription factor 3
chr17_+_32360673 0.21 ENSDART00000155519
si:ch211-139d20.3
chr20_+_26683933 0.21 ENSDART00000139852
ENSDART00000077751
forkhead box Q1b
chr5_+_26213874 0.21 ENSDART00000193816
ENSDART00000098514
occludin b
chr3_-_30909487 0.21 ENSDART00000025046
protein phosphatase 1, catalytic subunit, alpha isozyme a
chr16_+_41517188 0.21 ENSDART00000049976
si:dkey-11p23.7
chr12_+_5048044 0.21 ENSDART00000161548
ENSDART00000172607
kinesin family member 22
chr20_+_11731039 0.21 ENSDART00000152215
ENSDART00000152585
si:ch211-155o21.3
chr20_-_25626428 0.20 ENSDART00000136475
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr2_-_24348642 0.20 ENSDART00000181739
anoctamin 8a
chr1_-_59216197 0.20 ENSDART00000062426
lysophosphatidic acid receptor 2b
chr8_+_3405612 0.20 ENSDART00000163437
zgc:112433
chr8_-_38201415 0.20 ENSDART00000155189
PDZ and LIM domain 2 (mystique)
chr21_+_19347655 0.20 ENSDART00000093155
heparanase
chr9_+_2499627 0.20 ENSDART00000160782
WAS/WASL interacting protein family, member 1a
chr13_-_33256667 0.20 ENSDART00000003314
nucleolar and spindle associated protein 1
chr14_-_40821411 0.20 ENSDART00000166621
E74-like ETS transcription factor 1
chr1_-_18811517 0.20 ENSDART00000142026
si:dkey-167i21.2
chr1_+_23563691 0.20 ENSDART00000142879
non-SMC condensin I complex, subunit G
chr5_-_14500622 0.20 ENSDART00000099566
si:ch211-244o22.2
chr2_-_47620806 0.20 ENSDART00000038228
adaptor-related protein complex 1, sigma 3 subunit, b
chr20_-_25626198 0.20 ENSDART00000126716
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr5_-_10082244 0.20 ENSDART00000036421
checkpoint kinase 2
chr7_+_26549846 0.20 ENSDART00000141353
tyrosine kinase, non-receptor, 1
chr24_-_10006158 0.20 ENSDART00000106244
zgc:171750
chr6_+_120181 0.19 ENSDART00000151209
ENSDART00000185930
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr14_-_46374870 0.19 ENSDART00000185803
ENSDART00000188313
ENSDART00000031498
cyclin A2
chr7_-_18547420 0.19 ENSDART00000173969
regulator of G protein signaling 12a
chr14_+_1170968 0.19 ENSDART00000125203
ENSDART00000193575
HOP homeobox
chr13_-_14929236 0.19 ENSDART00000020576
cell division cycle 25B
chr2_-_985417 0.19 ENSDART00000140540
si:ch211-241e1.3
chr15_-_19724932 0.19 ENSDART00000152345
synaptotagmin-like 2b
chr19_-_340347 0.19 ENSDART00000139924
golgi phosphoprotein 3-like
chr2_+_24762567 0.19 ENSDART00000078866
interferon, gamma-inducible protein 30
chr11_-_40519886 0.19 ENSDART00000172819
migration and invasion inhibitory protein
chr13_-_15986871 0.19 ENSDART00000189394
IKAROS family zinc finger 1 (Ikaros)
chr19_-_3244360 0.19 ENSDART00000142222
zgc:158445
chr22_+_10543329 0.19 ENSDART00000091850
ATR interacting protein
chr23_-_3759345 0.19 ENSDART00000132205
ENSDART00000137707
ENSDART00000189382
high mobility group AT-hook 1a
chr5_-_42272517 0.19 ENSDART00000137692
ENSDART00000164363
si:ch211-207c6.2
chr22_-_29689981 0.18 ENSDART00000009223
programmed cell death 4b
chr17_+_32500387 0.18 ENSDART00000018423
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b
chr10_-_44305180 0.18 ENSDART00000187552
cyclin dependent kinase 2 associated protein 1
chr23_-_33775145 0.18 ENSDART00000132147
ENSDART00000027959
ENSDART00000160116
Rac GTPase activating protein 1
chr4_-_76370630 0.18 ENSDART00000168831
ENSDART00000174313
si:ch73-158p21.3
chr7_+_33457148 0.18 ENSDART00000133562
ENSDART00000074587
progestin and adipoQ receptor family member Vb
chr23_+_28374458 0.18 ENSDART00000140058
ENSDART00000144240
zgc:153867
chr19_-_47570672 0.18 ENSDART00000112155
ribonucleotide reductase M2 polypeptide
chr20_+_34770197 0.18 ENSDART00000018304
minichromosome maintenance complex component 3
chr10_+_26972755 0.17 ENSDART00000042162
transmembrane 7 superfamily member 2
chr20_+_6535176 0.17 ENSDART00000054652
si:ch211-191a24.4
chr14_+_3038473 0.17 ENSDART00000026021
ENSDART00000150000
CD74 molecule, major histocompatibility complex, class II invariant chain a
chr3_-_40276057 0.17 ENSDART00000132225
ENSDART00000074737
serine hydroxymethyltransferase 1 (soluble)
chr10_+_22724059 0.17 ENSDART00000136123
lysine (K)-specific demethylase 6B, b
chr17_+_24445818 0.17 ENSDART00000139963
UDP-glucose pyrophosphorylase 2b
chr16_-_51966846 0.17 ENSDART00000153959
phosducin-like
chr14_+_21145750 0.17 ENSDART00000187440
ENSDART00000059796
zgc:136929

Network of associatons between targets according to the STRING database.

First level regulatory network of fosaa+fosab+fosl1a

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0009794 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.1 0.4 GO:0009838 abscission(GO:0009838) mitotic cytokinesis checkpoint(GO:0044878)
0.1 0.3 GO:0046104 deoxyribonucleoside metabolic process(GO:0009120) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.1 0.4 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 0.3 GO:1902767 farnesyl diphosphate biosynthetic process, mevalonate pathway(GO:0010142) isoprenoid biosynthetic process via mevalonate(GO:1902767)
0.1 0.3 GO:0097384 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
0.1 0.5 GO:0048194 Golgi vesicle budding(GO:0048194)
0.1 0.3 GO:0008356 asymmetric cell division(GO:0008356)
0.1 0.3 GO:0002681 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.1 0.8 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 0.5 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.1 0.2 GO:0000212 meiotic spindle organization(GO:0000212)
0.1 0.6 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.1 0.2 GO:0097053 L-kynurenine metabolic process(GO:0097052) L-kynurenine catabolic process(GO:0097053)
0.1 0.3 GO:0046655 folic acid metabolic process(GO:0046655)
0.1 0.5 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.1 0.7 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.2 GO:0060907 dendritic cell antigen processing and presentation(GO:0002468) macrophage cytokine production(GO:0010934) regulation of macrophage cytokine production(GO:0010935) positive regulation of macrophage cytokine production(GO:0060907) negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.1 0.7 GO:0014034 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.1 0.3 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 0.2 GO:0046048 pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048)
0.1 0.2 GO:0070508 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.1 0.2 GO:0070255 regulation of mucus secretion(GO:0070255) positive regulation of mucus secretion(GO:0070257)
0.1 0.2 GO:0051352 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.1 0.2 GO:0052746 inositol phosphorylation(GO:0052746)
0.1 1.2 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.1 0.2 GO:0021564 vagus nerve development(GO:0021564)
0.1 0.4 GO:0006567 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.1 0.4 GO:0010826 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.1 1.4 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.1 0.2 GO:0034086 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0 0.3 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.3 GO:0003272 endocardial cushion formation(GO:0003272)
0.0 0.1 GO:0002369 T cell cytokine production(GO:0002369)
0.0 0.4 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.1 GO:0019408 dolichol biosynthetic process(GO:0019408)
0.0 0.3 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.2 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.4 GO:0071450 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0 0.1 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.2 GO:1904666 regulation of ubiquitin protein ligase activity(GO:1904666) positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.0 0.2 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.4 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.0 0.1 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.0 0.1 GO:0051230 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510) mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.0 0.1 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.2 GO:2001204 regulation of osteoclast development(GO:2001204)
0.0 0.2 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.0 0.1 GO:0033301 cell cycle comprising mitosis without cytokinesis(GO:0033301)
0.0 0.2 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.0 0.1 GO:0032207 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208)
0.0 0.1 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.0 0.1 GO:1903069 regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069)
0.0 0.1 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471)
0.0 0.4 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.1 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.1 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.0 0.3 GO:0000915 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.1 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.2 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0 0.1 GO:0010259 multicellular organism aging(GO:0010259)
0.0 0.1 GO:0007344 karyogamy(GO:0000741) pronuclear fusion(GO:0007344)
0.0 0.1 GO:0031055 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.3 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.3 GO:0045841 mitotic spindle assembly checkpoint(GO:0007094) spindle checkpoint(GO:0031577) negative regulation of mitotic metaphase/anaphase transition(GO:0045841) spindle assembly checkpoint(GO:0071173) mitotic spindle checkpoint(GO:0071174)
0.0 0.8 GO:0090307 mitotic spindle assembly(GO:0090307) microtubule cytoskeleton organization involved in mitosis(GO:1902850)
0.0 0.1 GO:0002566 somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.1 GO:0019388 galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
0.0 0.1 GO:2000815 regulation of mRNA stability involved in response to stress(GO:0010610) regulation of mRNA stability involved in response to oxidative stress(GO:2000815)
0.0 0.2 GO:0046959 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.0 0.1 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.1 GO:0060468 negative regulation of fertilization(GO:0060467) prevention of polyspermy(GO:0060468) cortical granule exocytosis(GO:0060471)
0.0 1.2 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.1 GO:0015871 choline transport(GO:0015871)
0.0 0.2 GO:1902315 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.0 0.1 GO:0030328 prenylated protein catabolic process(GO:0030327) prenylcysteine catabolic process(GO:0030328) prenylcysteine metabolic process(GO:0030329)
0.0 0.1 GO:0009957 epidermal cell fate specification(GO:0009957)
0.0 0.1 GO:0019240 citrulline biosynthetic process(GO:0019240)
0.0 0.1 GO:1901836 regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836)
0.0 0.4 GO:0042026 protein refolding(GO:0042026)
0.0 0.1 GO:0030521 androgen receptor signaling pathway(GO:0030521) regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.3 GO:0060337 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.2 GO:0044030 regulation of DNA methylation(GO:0044030)
0.0 0.1 GO:2001270 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.1 GO:0009085 lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878)
0.0 0.4 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0051310 metaphase plate congression(GO:0051310)
0.0 0.1 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.0 0.3 GO:0016126 sterol biosynthetic process(GO:0016126)
0.0 0.4 GO:0051642 centrosome localization(GO:0051642)
0.0 0.2 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 1.0 GO:0051225 spindle assembly(GO:0051225)
0.0 0.2 GO:0050714 positive regulation of protein secretion(GO:0050714)
0.0 0.2 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.0 0.3 GO:0071594 T cell differentiation in thymus(GO:0033077) thymocyte aggregation(GO:0071594)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:1903292 protein localization to Golgi membrane(GO:1903292)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.3 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.1 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.1 GO:0071042 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.0 0.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.2 GO:0044773 mitotic DNA damage checkpoint(GO:0044773) mitotic DNA integrity checkpoint(GO:0044774)
0.0 0.2 GO:0006901 vesicle coating(GO:0006901)
0.0 0.7 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.1 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.0 0.2 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.4 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.2 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of retinoic acid biosynthetic process(GO:1900052)
0.0 0.2 GO:0035307 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0 0.2 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.1 GO:0010269 response to selenium ion(GO:0010269)
0.0 0.1 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.0 GO:0030575 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576)
0.0 0.1 GO:0035889 otolith tethering(GO:0035889)
0.0 0.1 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.0 0.2 GO:1990118 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.1 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.0 0.1 GO:0043374 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:0038065 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.0 0.1 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.4 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.0 GO:0032847 regulation of cellular pH reduction(GO:0032847) synaptic vesicle lumen acidification(GO:0097401) regulation of synaptic vesicle lumen acidification(GO:1901546)
0.0 0.4 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.2 GO:0043687 post-translational protein modification(GO:0043687)
0.0 0.1 GO:1900120 regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.0 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:0070535 histone H2A K63-linked ubiquitination(GO:0070535)
0.0 0.2 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.2 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.1 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.0 0.1 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.0 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.0 0.1 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.1 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
0.0 0.2 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.1 GO:0050820 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.1 GO:0031640 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364) disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.0 0.1 GO:0030728 ovulation(GO:0030728)
0.0 0.1 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.0 0.1 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.0 0.1 GO:0021982 pineal gland development(GO:0021982)
0.0 0.1 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.2 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0 0.1 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.0 GO:1903358 regulation of Golgi organization(GO:1903358)
0.0 0.0 GO:0090299 regulation of neural crest formation(GO:0090299)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.1 0.8 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 0.3 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.1 0.9 GO:0070652 HAUS complex(GO:0070652)
0.1 0.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.2 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.1 0.2 GO:0005880 nuclear microtubule(GO:0005880)
0.1 0.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 0.2 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.3 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 0.2 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 1.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.4 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.1 GO:0098842 postsynaptic early endosome(GO:0098842)
0.0 0.7 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.4 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.1 GO:0097433 dense body(GO:0097433)
0.0 0.1 GO:0034709 methylosome(GO:0034709)
0.0 0.1 GO:0005592 collagen type XI trimer(GO:0005592)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.1 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.5 GO:0000780 condensed nuclear chromosome kinetochore(GO:0000778) condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.1 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.0 0.2 GO:0000796 condensin complex(GO:0000796)
0.0 0.1 GO:1904423 dehydrodolichyl diphosphate synthase complex(GO:1904423)
0.0 0.2 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.1 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.4 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.1 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.1 GO:0032301 MutSalpha complex(GO:0032301)
0.0 0.3 GO:0030130 trans-Golgi network transport vesicle membrane(GO:0012510) clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.2 GO:1990246 uniplex complex(GO:1990246)
0.0 0.2 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.1 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.1 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.0 0.4 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.2 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.2 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.3 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.0 GO:0030689 Noc complex(GO:0030689)
0.0 0.0 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.1 GO:0033061 DNA recombinase mediator complex(GO:0033061)
0.0 0.1 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.3 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.3 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.4 GO:0005657 replication fork(GO:0005657)
0.0 0.6 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.2 GO:0042555 MCM complex(GO:0042555)
0.0 1.1 GO:0005882 intermediate filament(GO:0005882)
0.0 0.1 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.0 GO:0043291 RAVE complex(GO:0043291)
0.0 0.0 GO:0090443 FAR/SIN/STRIPAK complex(GO:0090443)
0.0 0.2 GO:1990391 DNA repair complex(GO:1990391)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.3 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 0.4 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.1 0.3 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.1 0.3 GO:0001729 ceramide kinase activity(GO:0001729)
0.1 0.6 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 0.4 GO:0008743 L-threonine 3-dehydrogenase activity(GO:0008743)
0.1 0.2 GO:0003913 DNA photolyase activity(GO:0003913)
0.1 0.5 GO:0035173 histone kinase activity(GO:0035173)
0.1 0.5 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.1 0.2 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.1 0.4 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.2 GO:0070905 glycine hydroxymethyltransferase activity(GO:0004372) serine binding(GO:0070905)
0.1 0.5 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 0.2 GO:0009041 uridylate kinase activity(GO:0009041)
0.1 0.2 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 0.2 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.6 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0003994 aconitate hydratase activity(GO:0003994)
0.0 0.2 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.0 0.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.3 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.0 0.2 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.8 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.8 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.2 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.1 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.0 0.3 GO:0030619 U1 snRNA binding(GO:0030619)
0.0 0.6 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 0.3 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 2.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.2 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.0 0.3 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.2 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.1 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.0 0.2 GO:0033592 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.0 0.1 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.0 0.4 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494) granulocyte colony-stimulating factor binding(GO:0051916)
0.0 0.3 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.2 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.4 GO:0004859 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.0 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.1 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0 0.1 GO:0098808 mRNA cap binding(GO:0098808)
0.0 0.2 GO:0070330 aromatase activity(GO:0070330)
0.0 0.1 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.0 0.1 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0001735 prenylcysteine oxidase activity(GO:0001735)
0.0 0.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.1 GO:0097108 hedgehog family protein binding(GO:0097108)
0.0 0.1 GO:0045547 dehydrodolichyl diphosphate synthase activity(GO:0045547)
0.0 0.2 GO:0008312 7S RNA binding(GO:0008312)
0.0 0.4 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.2 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.1 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.1 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.0 0.1 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.2 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.1 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.2 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.0 0.1 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.0 0.3 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.3 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.9 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:0032143 guanine/thymine mispair binding(GO:0032137) single base insertion or deletion binding(GO:0032138) single thymine insertion binding(GO:0032143) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357) mismatch repair complex binding(GO:0032404) MutLalpha complex binding(GO:0032405)
0.0 0.1 GO:0031701 angiotensin receptor binding(GO:0031701)
0.0 0.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.1 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.0 0.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.1 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.3 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.2 GO:0031720 haptoglobin binding(GO:0031720)
0.0 0.2 GO:0015386 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.4 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.1 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.0 0.1 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.1 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.1 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 0.2 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0001130 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.0 0.1 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.0 GO:0080122 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.0 0.4 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.1 GO:0019778 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.0 0.4 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.2 GO:0016405 CoA-ligase activity(GO:0016405)
0.0 0.2 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.2 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.0 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.0 0.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.1 GO:0004001 adenosine kinase activity(GO:0004001)
0.0 0.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.0 GO:0050218 propionate-CoA ligase activity(GO:0050218)
0.0 0.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.2 GO:0022884 macromolecule transmembrane transporter activity(GO:0022884)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.0 PID PLK1 PATHWAY PLK1 signaling events
0.1 1.6 PID AURORA B PATHWAY Aurora B signaling
0.0 0.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.2 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway
0.0 0.5 PID ATM PATHWAY ATM pathway
0.0 0.3 PID AURORA A PATHWAY Aurora A signaling
0.0 0.3 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.1 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.1 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.0 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.6 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.3 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.4 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.3 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.6 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.2 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.3 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.5 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.6 PID E2F PATHWAY E2F transcription factor network
0.0 0.2 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.3 PID ATR PATHWAY ATR signaling pathway
0.0 0.1 NABA COLLAGENS Genes encoding collagen proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 0.5 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 1.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 0.7 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 0.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 1.3 REACTOME KINESINS Genes involved in Kinesins
0.1 0.6 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 0.7 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 0.2 REACTOME REGULATION OF MITOTIC CELL CYCLE Genes involved in Regulation of mitotic cell cycle
0.0 0.7 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.0 0.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.6 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.9 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 0.6 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.8 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.1 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0 0.3 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.1 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.4 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 1.4 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.3 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.1 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.2 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.8 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.3 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.3 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0 0.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.1 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.2 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.2 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.5 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 0.2 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.1 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway