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PRJNA207719: Tissue specific transcriptome profiling

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Results for etv5a+etv5b_elk1_elk4_etv1_elf1_erf+erfl3_gabpa_elk3

Z-value: 1.79

Transcription factors associated with etv5a+etv5b_elk1_elk4_etv1_elf1_erf+erfl3_gabpa_elk3

Gene Symbol Gene ID Gene Info
ENSDARG00000044511 ETS variant transcription factor 5b
ENSDARG00000069763 ETS variant transcription factor 5a
ENSDARG00000113729 ETS variant transcription factor 5a
ENSDARG00000113744 ETS variant transcription factor 5b
ENSDARG00000078066 ETS transcription factor ELK1
ENSDARG00000077092 ETS transcription factor ELK4
ENSDARG00000101959 ETS variant transcription factor 1
ENSDARG00000020759 E74-like ETS transcription factor 1
ENSDARG00000062801 Ets2 repressor factor like 3
ENSDARG00000063417 Ets2 repressor factor
ENSDARG00000069289 GA binding protein transcription factor subunit alpha
ENSDARG00000110923 GA binding protein transcription factor subunit alpha
ENSDARG00000018688 ETS transcription factor ELK3
ENSDARG00000110853 ETS transcription factor ELK3

Activity profile of etv5a+etv5b_elk1_elk4_etv1_elf1_erf+erfl3_gabpa_elk3 motif

Sorted Z-values of etv5a+etv5b_elk1_elk4_etv1_elf1_erf+erfl3_gabpa_elk3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_38762043 0.80 ENSDART00000036461
Rho GTPase activating protein 1
chr25_+_15354095 0.78 ENSDART00000090397
KIAA1549-like a
chr11_+_24907469 0.66 ENSDART00000008038
sulfatase 2a
chr18_+_29950233 0.65 ENSDART00000146431
ATM interactor
chr2_-_48298985 0.63 ENSDART00000057957
integral membrane protein 2Cb
chr2_-_11662851 0.62 ENSDART00000145108
zgc:110130
chr3_-_36440705 0.62 ENSDART00000162875
rogdi homolog (Drosophila)
chr9_-_29643628 0.60 ENSDART00000101177
SPRY domain containing 7b
chr12_-_28881638 0.59 ENSDART00000148459
ENSDART00000039667
ENSDART00000148668
ENSDART00000136593
ENSDART00000139923
ENSDART00000148912
chromobox homolog 1b (HP1 beta homolog Drosophila)
chr10_+_26571174 0.56 ENSDART00000148617
ENSDART00000112956
solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6b
chr12_+_45200744 0.53 ENSDART00000098932
WW domain binding protein 2
chr17_+_23937262 0.52 ENSDART00000113276
si:ch211-189k9.2
chr16_+_26680508 0.52 ENSDART00000142215
ENSDART00000159064
vir like m6A methyltransferase associated
chr19_+_9150041 0.51 ENSDART00000127803
ENSDART00000091533
CDC-like kinase 2a
chr25_-_13659249 0.51 ENSDART00000045488
casein kinase 2, alpha prime polypeptide b
chr19_-_1871415 0.51 ENSDART00000004585
CLPTM1-like
chr19_+_8506178 0.51 ENSDART00000189689
S100 calcium binding protein A10a
chr7_-_36358735 0.50 ENSDART00000188392
fat mass and obesity associated
chr7_-_36358303 0.50 ENSDART00000130028
fat mass and obesity associated
chr1_-_7917062 0.50 ENSDART00000177068
monocyte to macrophage differentiation-associated 2b
chr4_-_240737 0.49 ENSDART00000166186
si:cabz01085950.1
chr16_+_10318893 0.48 ENSDART00000055380
tubulin, beta 5
chr13_-_18691041 0.48 ENSDART00000057867
sideroflexin 3
chr16_+_25316973 0.48 ENSDART00000086409
dynein, cytoplasmic 1, intermediate chain 1
chr19_-_17385548 0.47 ENSDART00000162383
NFKB inhibitor interacting Ras-like 1
chr7_+_74141297 0.47 ENSDART00000164992
RNA binding protein with multiple splicing
chr16_-_5154024 0.47 ENSDART00000132069
ENSDART00000060635
dynactin 3 (p22)
chr22_-_37611681 0.47 ENSDART00000028085
tetratricopeptide repeat domain 14
chr25_+_14694876 0.46 ENSDART00000050478
ENSDART00000188093
metallophosphoesterase domain containing 2b
chr19_-_19599372 0.45 ENSDART00000160002
ENSDART00000171664
Tax1 (human T-cell leukemia virus type I) binding protein 1a
chr4_-_9667380 0.45 ENSDART00000189671
ENSDART00000133214
cyclin D binding myb-like transcription factor 1
chr15_-_11683529 0.45 ENSDART00000161445
fukutin related protein
chr5_+_69733096 0.45 ENSDART00000169013
ADP-ribosylation factor-like 6 interacting protein 4
chr22_-_11833317 0.45 ENSDART00000125423
ENSDART00000000192
protein tyrosine phosphatase, non-receptor type 4b
chr10_+_11282883 0.44 ENSDART00000135355
si:ch211-126i22.5
chr15_-_97205 0.43 ENSDART00000158734
beta-secretase 1
chr22_+_35275468 0.43 ENSDART00000189516
ENSDART00000181572
ENSDART00000165353
ENSDART00000185352
RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein
chr6_-_29288155 0.43 ENSDART00000078630
NME/NM23 family member 7
chr16_-_45001842 0.43 ENSDART00000037797
sulfotransferase family 2, cytosolic sulfotransferase 3
chr9_-_23824290 0.43 ENSDART00000059209
WD repeat and FYVE domain containing 2
chr1_+_34685405 0.42 ENSDART00000037986
ENSDART00000166007
GPALPP motifs containing 1
chr21_+_19925910 0.42 ENSDART00000111694
ENSDART00000132653
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase a
chr7_+_7511914 0.42 ENSDART00000172848
chloride channel 3
chr22_-_11829436 0.42 ENSDART00000126784
protein tyrosine phosphatase, non-receptor type 4b
chr20_-_14462995 0.41 ENSDART00000152418
ENSDART00000044125
gene rich cluster, C10 gene
chr19_-_42416696 0.40 ENSDART00000086961
vacuolar protein sorting 45 homolog (S. cerevisiae)
chr5_-_31716713 0.40 ENSDART00000131443
dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
chr21_-_19828423 0.40 ENSDART00000037664
nicotinamide nucleotide transhydrogenase
chr2_+_9061885 0.40 ENSDART00000028906
phosphatidylinositol glycan anchor biosynthesis, class K
chr4_+_28374628 0.39 ENSDART00000076037
asparagine-linked glycosylation 10
chr22_+_33362552 0.39 ENSDART00000101580
nicolin 1
chr1_-_22338521 0.39 ENSDART00000176849
si:ch73-380n15.2
chr4_+_9612574 0.39 ENSDART00000150336
ENSDART00000041289
ENSDART00000150828
transmembrane protein 243, mitochondrial b
chr3_-_32902138 0.39 ENSDART00000144026
ENSDART00000083874
ENSDART00000145443
ENSDART00000148239
ENSDART00000134917
K(lysine) acetyltransferase 7a
chr2_+_35854242 0.38 ENSDART00000134918
DEAH (Asp-Glu-Ala-His) box helicase 9
chr11_+_2699951 0.38 ENSDART00000082512
transmembrane protein 167B
chr12_+_20667301 0.38 ENSDART00000144804
matrix-remodelling associated 7
chr22_+_35275206 0.37 ENSDART00000112234
RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein
chr12_+_19036380 0.37 ENSDART00000153086
ENSDART00000181060
potassium channel tetramerization domain containing 17
chr15_-_46718759 0.37 ENSDART00000085926
ENSDART00000154577
zgc:162872
chr14_-_25099988 0.37 ENSDART00000144168
matrin 3-like 1.1
chr12_-_26491464 0.36 ENSDART00000153361
si:dkey-287g12.6
chr19_-_27006764 0.36 ENSDART00000089540
SAC1 like phosphatidylinositide phosphatase a
chr21_-_30994577 0.36 ENSDART00000065503
post-GPI attachment to proteins 2
chr19_+_5604241 0.36 ENSDART00000011025
WAS/WASL interacting protein family, member 2b
chr10_-_29744921 0.35 ENSDART00000088605
intraflagellar transport 46 homolog (Chlamydomonas)
chr20_+_26892761 0.35 ENSDART00000133293
finTRIM family, member 97
chr6_-_17849786 0.35 ENSDART00000172709
regulatory associated protein of MTOR, complex 1
chr16_+_38119004 0.35 ENSDART00000132087
pogo transposable element derived with ZNF domain b
chr2_+_21452822 0.35 ENSDART00000169028
AFG3-like AAA ATPase 2
chr20_+_2950005 0.35 ENSDART00000135919
adenosylmethionine decarboxylase 1
chr20_+_18943406 0.35 ENSDART00000193590
myotubularin related protein 9
chr10_+_21576909 0.35 ENSDART00000168604
ENSDART00000166533
protocadherin 1 alpha 3
chr10_-_41157135 0.35 ENSDART00000134851
AP2 associated kinase 1b
chr9_-_889567 0.35 ENSDART00000155921
si:ch73-250a16.5
chr8_+_2757821 0.35 ENSDART00000051403
ENSDART00000160551
SH3-domain GRB2-like endophilin B2a
chr5_-_69482891 0.34 ENSDART00000109487

chr3_+_13440900 0.34 ENSDART00000143715
si:dkey-117i10.1
chr2_+_5887626 0.34 ENSDART00000147831
si:ch211-168b3.1
chr24_-_25004553 0.34 ENSDART00000080997
ENSDART00000136860
zinc finger, DHHC-type containing 20b
chr1_+_11977426 0.34 ENSDART00000103399
tetraspanin 5b
chr4_-_858434 0.33 ENSDART00000006961
sine oculis binding protein homolog (Drosophila) b
chr5_-_26795438 0.33 ENSDART00000146124
si:ch211-102c2.7
chr8_-_11546175 0.33 ENSDART00000081909
si:ch211-248e11.2
chr7_+_24496894 0.33 ENSDART00000149994
negative elongation factor complex member A
chr22_-_20950448 0.33 ENSDART00000002029
FK506 binding protein 8
chr21_-_36453594 0.33 ENSDART00000193176
CCR4-NOT transcription complex, subunit 8
chr1_-_45341760 0.33 ENSDART00000149183
ENSDART00000148289
ENSDART00000110390
zgc:101679
chr12_-_17810543 0.33 ENSDART00000090484
tectonin beta-propeller repeat containing 1a
chr9_+_13733468 0.33 ENSDART00000165954
ENSDART00000160355
ENSDART00000081040
ENSDART00000138254
ENSDART00000081015
ENSDART00000141314
abl-interactor 2a
chr19_-_13923091 0.32 ENSDART00000169993
ENSDART00000158992
syntaxin 12
chr14_-_24251057 0.32 ENSDART00000114169
BCL2 interacting protein 1a
chr8_+_53388005 0.32 ENSDART00000171920
decapping mRNA 1A
chr5_-_55933420 0.31 ENSDART00000050966
solute carrier family 25, member 46
chr10_+_36439293 0.31 ENSDART00000043802
ubiquitin specific peptidase like 1
chr16_+_12286148 0.31 ENSDART00000130736
si:dkey-26c10.5
chr20_-_42972599 0.31 ENSDART00000100751
proopiomelanocortin b
chr17_+_52822422 0.31 ENSDART00000158273
ENSDART00000161414
Meis homeobox 2a
chr8_+_36500061 0.31 ENSDART00000185840
solute carrier family 7, member 4
chr14_-_30876708 0.31 ENSDART00000147597
ubiquitin-like 3b
chr10_+_44903676 0.31 ENSDART00000158553
zgc:114173
chr12_-_25097520 0.31 ENSDART00000158036
cysteine-rich PDZ-binding protein
chr24_+_10397865 0.30 ENSDART00000155557
si:ch211-69l10.4
chr1_-_44581937 0.30 ENSDART00000009858
thioredoxin-related transmembrane protein 2b
chr19_-_25271155 0.30 ENSDART00000104027
regulating synaptic membrane exocytosis 3
chr10_+_5135842 0.30 ENSDART00000132627
ENSDART00000162434
zgc:113274
chr23_+_23918421 0.29 ENSDART00000046951
protein tyrosine phosphatase, non-receptor type 11, b
chr1_+_45671687 0.29 ENSDART00000146101
mucolipin 1a
chr1_-_10473630 0.29 ENSDART00000040116
trinucleotide repeat containing 5
chr16_-_34285106 0.29 ENSDART00000044235
phosphatase and actin regulator 4b
chr4_-_18840919 0.29 ENSDART00000015834
Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
chr5_-_11943750 0.29 ENSDART00000074979
ring finger protein, transmembrane 2
chr17_+_39790388 0.29 ENSDART00000149488
ubiquitin protein ligase E3 component n-recognin 1
chr17_+_37253706 0.29 ENSDART00000076004
transmembrane protein 62
chr9_-_22918413 0.29 ENSDART00000007392
ADP-ribosylation factor-like 5A
chr19_-_8880688 0.29 ENSDART00000039629
cugbp, Elav-like family member 3a
chr14_-_30876299 0.28 ENSDART00000180305
ubiquitin-like 3b
chr2_-_42173834 0.28 ENSDART00000098357
ENSDART00000144707
solute carrier family 39 (zinc transporter), member 6
chr5_-_68826177 0.28 ENSDART00000136605
si:ch211-283h6.4
chr14_+_16083818 0.28 ENSDART00000168462
ring finger protein 103
chr3_+_27786601 0.28 ENSDART00000086994
N-acetyltransferase 15 (GCN5-related, putative)
chr8_+_8973425 0.28 ENSDART00000066107
B cell receptor associated protein 31
chr20_-_20610812 0.28 ENSDART00000181870
protein phosphatase, Mg2+/Mn2+ dependent, 1Ab
chr1_+_40034061 0.28 ENSDART00000011727
coiled-coil domain containing 149b
chr14_+_7939398 0.27 ENSDART00000189773
CXXC finger protein 5b
chr23_-_14216506 0.27 ENSDART00000019620
DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
chr5_+_39994283 0.27 ENSDART00000112728
transmembrane protein 175
chr8_+_53423408 0.27 ENSDART00000164792
calcium channel, voltage-dependent, L type, alpha 1D subunit, b
chr21_+_31434251 0.27 ENSDART00000040740
ENSDART00000130157
si:ch211-12m10.1
si:ch211-166i24.1
chr16_-_17345377 0.27 ENSDART00000143056
zyxin
chr20_-_33174899 0.27 ENSDART00000047834
neuroblastoma amplified sequence
chr2_+_38055529 0.27 ENSDART00000145642
si:rp71-1g18.1
chr4_-_20051141 0.26 ENSDART00000066963
ATPase H+ transporting V1 subunit F
chr6_+_35052721 0.26 ENSDART00000191090
ENSDART00000082940
U2AF homology motif (UHM) kinase 1
chr16_+_33987892 0.26 ENSDART00000166302
phosphatidylinositol glycan anchor biosynthesis, class V
chr3_-_14498295 0.26 ENSDART00000172102
ELF1 homolog, elongation factor 1
chr21_+_28502340 0.26 ENSDART00000077897
ENSDART00000140229
OTU deubiquitinase, ubiquitin aldehyde binding 1a
chr6_-_18250857 0.25 ENSDART00000159486
APC11 anaphase promoting complex subunit 11 homolog (yeast)
chr3_-_43821381 0.25 ENSDART00000166021
stannin
chr16_+_12812214 0.25 ENSDART00000124875
U2 small nuclear RNA auxiliary factor 2a
chr11_+_24348425 0.25 ENSDART00000089747
NFS1 cysteine desulfurase
chr2_-_32505091 0.25 ENSDART00000141884
ENSDART00000056639
Fas apoptotic inhibitory molecule 2a
chr17_+_38295847 0.25 ENSDART00000008532
MAP3K12 binding inhibitory protein 1
chr12_+_25097754 0.25 ENSDART00000050070
phosphatidylinositol glycan anchor biosynthesis, class F
chr21_+_26028947 0.25 ENSDART00000028007
SPT6 homolog, histone chaperone
chr24_-_8777781 0.24 ENSDART00000082362
ENSDART00000177400
male germ cell-associated kinase
chr14_+_28438947 0.24 ENSDART00000006489
acyl-CoA synthetase long chain family member 4a
chr20_-_20611063 0.24 ENSDART00000063492
protein phosphatase, Mg2+/Mn2+ dependent, 1Ab
chr13_-_30662403 0.24 ENSDART00000012457
si:dkey-275b16.2
chr5_-_56119028 0.24 ENSDART00000083134
Meckel syndrome, type 1
chr11_-_42350791 0.24 ENSDART00000160661
ENSDART00000165531
sarcolemma associated protein a
chr22_-_28373698 0.24 ENSDART00000157592
si:ch211-213c4.5
chr3_-_35554809 0.24 ENSDART00000010944
dynactin 5
chr14_+_29581710 0.24 ENSDART00000188820
ENSDART00000193874
si:dkey-34l15.2
chr10_-_13239367 0.24 ENSDART00000001253
si:busm1-57f23.1
chr3_-_6767440 0.24 ENSDART00000156174
microtubule associated serine/threonine kinase 1b
chr7_-_49351706 0.24 ENSDART00000174151
BR serine/threonine kinase 2b
chr4_-_18841071 0.24 ENSDART00000140722
Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
chr9_+_44721808 0.24 ENSDART00000190578
NCK-associated protein 1
chr13_-_24396003 0.24 ENSDART00000016211
TATA box binding protein
chr24_-_8409641 0.23 ENSDART00000149662
ENSDART00000149025
solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3
chr20_+_14968031 0.23 ENSDART00000151805
ENSDART00000151448
ENSDART00000063874
ENSDART00000190910
vesicle-associated membrane protein 4
chr8_-_22508055 0.23 ENSDART00000101616
si:ch211-261n11.5
chr9_+_44722205 0.23 ENSDART00000086176
ENSDART00000145271
ENSDART00000132696
NCK-associated protein 1
chr22_+_29648854 0.23 ENSDART00000146280
BBSome interacting protein 1
chr10_-_15405564 0.23 ENSDART00000020665
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr24_+_3478871 0.23 ENSDART00000111491
ENSDART00000134598
ENSDART00000142407
WD repeat domain 37
chr2_+_30904069 0.23 ENSDART00000017144
BCL2 associated athanogene 1
chr6_-_39631164 0.23 ENSDART00000104042
ENSDART00000136076
activating transcription factor 7b
chr16_+_12812472 0.23 ENSDART00000008535
U2 small nuclear RNA auxiliary factor 2a
chr10_-_2524297 0.23 ENSDART00000192475

chr15_+_14642641 0.23 ENSDART00000172482
seryl-tRNA synthetase 2, mitochondrial
chr1_+_52130213 0.23 ENSDART00000018817
ring finger protein 11a
chr10_-_35220285 0.23 ENSDART00000180439
yippee-like 2a
chr8_+_25761654 0.22 ENSDART00000137899
ENSDART00000062403
transmembrane protein 9
chr24_+_15020402 0.22 ENSDART00000148102
docking protein 6
chr2_+_38924975 0.22 ENSDART00000109219
RAS (RAD and GEM)-like GTP binding 2
chr14_-_30724165 0.22 ENSDART00000020936
fibroblast growth factor (acidic) intracellular binding protein a
chr12_+_32073660 0.22 ENSDART00000153245
ENSDART00000153268
syntaxin binding protein 4
chr24_+_37533728 0.22 ENSDART00000061203
ras homolog family member T2
chr7_+_69470142 0.22 ENSDART00000073861
GABA(A) receptor-associated protein b
chr7_+_69470442 0.22 ENSDART00000189593
GABA(A) receptor-associated protein b
chr21_-_30181732 0.22 ENSDART00000015636
heterogeneous nuclear ribonucleoprotein H1, like
chr24_+_5208171 0.22 ENSDART00000155926
ENSDART00000154464
si:ch73-206p6.1
chr1_-_8980665 0.22 ENSDART00000148182
si:ch73-191k20.3
chr25_-_28768489 0.22 ENSDART00000088315
WASH complex subunit 4
chr10_+_37268854 0.22 ENSDART00000131897
neurofibromin 1b
chr9_-_30243393 0.22 ENSDART00000089539
si:dkey-100n23.3
chr21_+_17542473 0.22 ENSDART00000005750
ENSDART00000141326
stomatin
chr22_-_881725 0.22 ENSDART00000035514
choline/ethanolamine phosphotransferase 1b
chr13_+_482911 0.22 ENSDART00000134884
F-box protein 28
chr1_+_38818268 0.22 ENSDART00000166864
signal peptidase complex subunit 3
chr5_+_11943792 0.21 ENSDART00000114873
zgc:110063
chr1_-_59021796 0.21 ENSDART00000168314
zgc:153247
chr5_+_68826514 0.21 ENSDART00000061406
ubiquitin specific peptidase 39
chr4_+_29773917 0.21 ENSDART00000170798

chr17_+_25426091 0.21 ENSDART00000149241
ENSDART00000121848
serine/arginine repetitive matrix 1
chr7_+_53754653 0.21 ENSDART00000163261
ENSDART00000158160
neogenin 1a
chr24_-_33780387 0.21 ENSDART00000079210
cyclin-dependent kinase 5
chr1_+_59007536 0.21 ENSDART00000165339
cell division cycle 37

Network of associatons between targets according to the STRING database.

First level regulatory network of etv5a+etv5b_elk1_elk4_etv1_elf1_erf+erfl3_gabpa_elk3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0042245 RNA repair(GO:0042245)
0.3 0.8 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) negative regulation of lipid kinase activity(GO:0090219)
0.2 0.8 GO:0010561 negative regulation of glycoprotein biosynthetic process(GO:0010561) negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) negative regulation of glycoprotein metabolic process(GO:1903019)
0.1 0.4 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.1 0.4 GO:0035019 somatic stem cell population maintenance(GO:0035019) symmetric cell division(GO:0098725)
0.1 0.4 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.1 0.5 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.1 0.4 GO:0006740 NADPH regeneration(GO:0006740)
0.1 0.4 GO:1904355 positive regulation of telomere maintenance(GO:0032206) regulation of telomere capping(GO:1904353) positive regulation of telomere capping(GO:1904355)
0.1 0.6 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.3 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.1 0.3 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.1 0.4 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 0.2 GO:1903441 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to ciliary membrane(GO:1903441)
0.1 0.2 GO:1903332 regulation of protein folding(GO:1903332) positive regulation of protein folding(GO:1903334) regulation of chaperone-mediated protein folding(GO:1903644) positive regulation of chaperone-mediated protein folding(GO:1903646)
0.1 0.4 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.3 GO:1903292 protein localization to Golgi membrane(GO:1903292)
0.1 0.1 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.1 0.3 GO:2000622 negative regulation of mRNA catabolic process(GO:1902373) regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 0.2 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.1 0.3 GO:1904867 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576) protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) protein localization to nucleoplasm(GO:1990173)
0.1 0.2 GO:0018410 C-terminal protein amino acid modification(GO:0018410)
0.1 0.4 GO:1901314 negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.1 0.2 GO:0090161 Golgi ribbon formation(GO:0090161)
0.1 0.3 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.2 GO:2000378 negative regulation of reactive oxygen species metabolic process(GO:2000378)
0.1 0.5 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 0.3 GO:1901207 regulation of heart looping(GO:1901207)
0.1 0.2 GO:0071733 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.1 0.2 GO:2000009 regulation of protein localization to cell surface(GO:2000008) negative regulation of protein localization to cell surface(GO:2000009)
0.1 1.1 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 0.1 GO:0007414 axonal defasciculation(GO:0007414)
0.1 0.2 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 0.6 GO:1990118 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.2 GO:0086005 ventricular cardiac muscle cell action potential(GO:0086005)
0.0 0.2 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.1 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.3 GO:0060251 regulation of glial cell proliferation(GO:0060251)
0.0 0.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.4 GO:0034982 mitochondrial protein processing(GO:0034982)
0.0 0.1 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.2 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.2 GO:0048855 adenohypophysis morphogenesis(GO:0048855)
0.0 0.4 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.4 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.1 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.0 0.2 GO:0051645 Golgi localization(GO:0051645)
0.0 0.2 GO:1900744 regulation of p38MAPK cascade(GO:1900744)
0.0 0.2 GO:0006788 heme oxidation(GO:0006788)
0.0 0.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.0 0.1 GO:0009838 abscission(GO:0009838) mitotic cytokinesis checkpoint(GO:0044878)
0.0 0.1 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.1 GO:0034770 histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773)
0.0 0.3 GO:0048478 replication fork protection(GO:0048478)
0.0 0.5 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.1 GO:0061400 positive regulation of transcription from RNA polymerase II promoter in response to calcium ion(GO:0061400)
0.0 0.2 GO:0021634 optic nerve formation(GO:0021634)
0.0 0.2 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.0 0.2 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0 0.1 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.4 GO:0009791 post-embryonic development(GO:0009791)
0.0 0.5 GO:0035860 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.1 GO:0035522 monoubiquitinated protein deubiquitination(GO:0035520) monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.4 GO:1902101 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.3 GO:0046822 regulation of nucleocytoplasmic transport(GO:0046822)
0.0 0.2 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.1 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.2 GO:0097355 protein localization to heterochromatin(GO:0097355)
0.0 0.1 GO:0061010 gall bladder development(GO:0061010)
0.0 0.1 GO:1903069 regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069)
0.0 0.2 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.4 GO:0032785 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.3 GO:0061075 positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868)
0.0 0.3 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.5 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.1 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.0 0.0 GO:0014009 glial cell proliferation(GO:0014009)
0.0 0.1 GO:0008344 adult locomotory behavior(GO:0008344)
0.0 0.3 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.1 GO:1903173 fatty alcohol metabolic process(GO:1903173)
0.0 0.4 GO:0006596 polyamine biosynthetic process(GO:0006596)
0.0 0.1 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.1 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 0.2 GO:0044211 CTP salvage(GO:0044211)
0.0 0.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.8 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.0 GO:1990120 messenger ribonucleoprotein complex assembly(GO:1990120)
0.0 0.3 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.1 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
0.0 0.2 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.0 0.1 GO:0031053 primary miRNA processing(GO:0031053)
0.0 0.4 GO:0046660 female sex differentiation(GO:0046660)
0.0 0.3 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.2 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.4 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 0.1 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.4 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.2 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.0 0.8 GO:0045815 positive regulation of gene expression, epigenetic(GO:0045815)
0.0 0.1 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.4 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.0 GO:0043576 respiratory gaseous exchange(GO:0007585) regulation of respiratory gaseous exchange(GO:0043576)
0.0 0.8 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.1 GO:0038107 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.0 0.2 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.1 GO:0070572 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.0 0.2 GO:0003262 endocardial progenitor cell migration to the midline involved in heart field formation(GO:0003262)
0.0 0.4 GO:1901654 response to ketone(GO:1901654)
0.0 0.4 GO:0007032 endosome organization(GO:0007032)
0.0 0.1 GO:0021961 posterior commissure morphogenesis(GO:0021961)
0.0 0.4 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.1 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 0.0 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.1 GO:0018315 establishment of synaptic specificity at neuromuscular junction(GO:0007529) molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.0 0.1 GO:0090247 hindbrain structural organization(GO:0021577) dorsal fin morphogenesis(GO:0035142) cell motility involved in somitogenic axis elongation(GO:0090247) cell migration involved in somitogenic axis elongation(GO:0090248)
0.0 0.4 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 0.1 GO:0030194 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.0 0.4 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.2 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.1 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.6 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.1 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.0 0.4 GO:0035675 neuromast hair cell development(GO:0035675)
0.0 0.1 GO:0030299 intestinal cholesterol absorption(GO:0030299)
0.0 0.1 GO:0070291 N-acylethanolamine metabolic process(GO:0070291)
0.0 0.4 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.2 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.1 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.6 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.5 GO:0019835 cytolysis(GO:0019835)
0.0 0.1 GO:0090308 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.0 GO:0002888 positive regulation of myeloid leukocyte mediated immunity(GO:0002888)
0.0 0.2 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.0 0.2 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.1 GO:0048714 positive regulation of gliogenesis(GO:0014015) positive regulation of glial cell differentiation(GO:0045687) positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0 0.5 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.0 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.2 GO:0000394 RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394)
0.0 0.2 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.3 GO:0001556 oocyte maturation(GO:0001556)
0.0 0.5 GO:0071230 cellular response to amino acid stimulus(GO:0071230)
0.0 0.3 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0 0.0 GO:0010664 negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.0 0.0 GO:0042772 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.0 0.1 GO:0099563 modification of synaptic structure(GO:0099563)
0.0 0.1 GO:0006337 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 0.1 GO:0032367 intracellular cholesterol transport(GO:0032367)
0.0 0.0 GO:2000639 response to sterol(GO:0036314) cellular response to sterol(GO:0036315) SREBP-SCAP complex retention in endoplasmic reticulum(GO:0036316) regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.0 GO:0051958 folic acid transport(GO:0015884) drug transport(GO:0015893) methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.0 0.0 GO:0001112 DNA-templated transcriptional open complex formation(GO:0001112) transcriptional open complex formation at RNA polymerase II promoter(GO:0001113) protein-DNA complex remodeling(GO:0001120)
0.0 0.1 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0 0.1 GO:0030101 natural killer cell activation(GO:0030101)
0.0 0.0 GO:1900274 positive regulation of phospholipase C activity(GO:0010863) regulation of phospholipase C activity(GO:1900274)
0.0 0.0 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.0 0.2 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.1 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.2 GO:0046688 response to copper ion(GO:0046688)
0.0 0.1 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.1 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.0 0.0 GO:0045601 positive regulation of epithelial cell differentiation(GO:0030858) regulation of endothelial cell differentiation(GO:0045601)
0.0 0.2 GO:0003209 cardiac atrium morphogenesis(GO:0003209)
0.0 0.1 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.1 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.3 GO:0090148 membrane fission(GO:0090148)
0.0 0.1 GO:0030952 establishment or maintenance of cytoskeleton polarity(GO:0030952) mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.0 0.1 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.0 0.4 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.3 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.1 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.1 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.0 0.1 GO:0043584 nose development(GO:0043584)
0.0 0.1 GO:0043550 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.1 GO:0032469 endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.0 0.0 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364)
0.0 0.1 GO:0032978 protein insertion into membrane from inner side(GO:0032978) protein insertion into mitochondrial membrane from inner side(GO:0032979) protein insertion into mitochondrial membrane(GO:0051204)
0.0 0.0 GO:0009397 10-formyltetrahydrofolate metabolic process(GO:0009256) 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.0 0.2 GO:0009086 methionine biosynthetic process(GO:0009086)
0.0 0.2 GO:0000959 mitochondrial RNA metabolic process(GO:0000959)
0.0 0.0 GO:0002312 B cell activation involved in immune response(GO:0002312) isotype switching(GO:0045190)
0.0 0.2 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.0 GO:1903573 negative regulation of response to endoplasmic reticulum stress(GO:1903573)
0.0 0.7 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.1 GO:0044209 AMP salvage(GO:0044209)
0.0 0.1 GO:0017006 protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063)
0.0 0.1 GO:0048730 epidermis morphogenesis(GO:0048730)
0.0 0.0 GO:0018210 peptidyl-threonine modification(GO:0018210)
0.0 0.3 GO:0050821 protein stabilization(GO:0050821)
0.0 0.4 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.1 GO:0090520 sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.0 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.1 GO:0009180 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.0 0.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.0 GO:0045911 positive regulation of DNA recombination(GO:0045911)
0.0 0.1 GO:0061056 sclerotome development(GO:0061056)
0.0 0.0 GO:0061355 Wnt protein secretion(GO:0061355)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0043291 RAVE complex(GO:0043291)
0.1 0.4 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 0.3 GO:0031501 mannosyltransferase complex(GO:0031501)
0.1 0.6 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 0.4 GO:0005787 signal peptidase complex(GO:0005787)
0.1 0.5 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.2 GO:0072380 TRC complex(GO:0072380)
0.1 0.2 GO:0031251 PAN complex(GO:0031251)
0.1 0.3 GO:0032838 cell projection cytoplasm(GO:0032838)
0.1 0.2 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 0.3 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.1 0.5 GO:0089701 U2AF(GO:0089701)
0.0 0.2 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.6 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 0.3 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.4 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.4 GO:0032021 NELF complex(GO:0032021)
0.0 0.5 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.2 GO:0030897 HOPS complex(GO:0030897)
0.0 0.5 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.3 GO:0016586 RSC complex(GO:0016586)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.3 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.5 GO:0005869 dynactin complex(GO:0005869)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 0.5 GO:0015030 Cajal body(GO:0015030)
0.0 0.4 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.1 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.0 GO:0042382 paraspeckles(GO:0042382)
0.0 0.2 GO:0070449 elongin complex(GO:0070449)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.8 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.1 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.0 0.2 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.4 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 2.0 GO:0016607 nuclear speck(GO:0016607)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.0 0.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0070390 transcription export complex 2(GO:0070390)
0.0 0.2 GO:0036038 MKS complex(GO:0036038)
0.0 0.1 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.0 0.0 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 0.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.0 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.2 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 1.8 GO:0005770 late endosome(GO:0005770)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.2 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.5 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.1 GO:0000938 GARP complex(GO:0000938)
0.0 0.8 GO:0098573 intrinsic component of mitochondrial membrane(GO:0098573)
0.0 0.7 GO:0016592 mediator complex(GO:0016592)
0.0 0.3 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.0 0.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.0 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.1 GO:0000124 SAGA complex(GO:0000124)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.2 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.3 GO:0035371 microtubule plus-end(GO:0035371)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0043734 DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.1 0.4 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 0.4 GO:0042166 neurotransmitter binding(GO:0042165) acetylcholine binding(GO:0042166)
0.1 0.4 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1 0.4 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 0.5 GO:0022889 serine transmembrane transporter activity(GO:0022889)
0.1 0.3 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 0.4 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 0.3 GO:0032183 SUMO binding(GO:0032183)
0.1 0.3 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 0.3 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.2 GO:0080122 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.1 0.3 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.1 0.2 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 0.8 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.5 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 0.5 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 0.3 GO:0016531 copper chaperone activity(GO:0016531)
0.1 0.6 GO:0015385 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.3 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.0 0.2 GO:0017064 fatty acid amide hydrolase activity(GO:0017064)
0.0 0.1 GO:0030623 U5 snRNA binding(GO:0030623)
0.0 0.1 GO:0070738 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.0 0.3 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.0 1.0 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.1 GO:0047453 ATP-dependent NAD(P)H-hydrate dehydratase activity(GO:0047453) ADP-dependent NAD(P)H-hydrate dehydratase activity(GO:0052855)
0.0 0.0 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086)
0.0 0.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.2 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 0.5 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.3 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.4 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.0 0.4 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.2 GO:0046592 polyamine oxidase activity(GO:0046592)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.3 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.6 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.2 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.0 0.2 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.3 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.2 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.5 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.2 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.2 GO:0051998 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0 0.2 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.2 GO:0030619 U1 snRNA binding(GO:0030619)
0.0 0.1 GO:0017050 D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.3 GO:0070122 isopeptidase activity(GO:0070122)
0.0 0.1 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 0.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.3 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.1 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.2 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.1 GO:0031782 type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.1 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.0 0.1 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.0 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.5 GO:0005112 Notch binding(GO:0005112)
0.0 0.5 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.1 GO:0001147 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.0 0.1 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.0 0.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.1 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.1 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.2 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.2 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.7 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.4 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.1 GO:0008117 sphinganine-1-phosphate aldolase activity(GO:0008117)
0.0 0.0 GO:0045545 syndecan binding(GO:0045545)
0.0 0.4 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.2 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.0 GO:0015350 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.0 0.1 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0 0.2 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.3 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.2 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.3 GO:0052744 phosphatidylinositol-3-phosphatase activity(GO:0004438) phosphatidylinositol monophosphate phosphatase activity(GO:0052744)
0.0 0.3 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0019206 nucleoside kinase activity(GO:0019206)
0.0 0.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.2 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.9 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.0 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.2 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.0 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.0 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.0 0.0 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.0 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.1 GO:0004408 holocytochrome-c synthase activity(GO:0004408)
0.0 0.3 GO:0022842 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.0 GO:1990430 extracellular matrix protein binding(GO:1990430)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.7 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.9 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.0 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.2 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.1 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.6 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.2 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.1 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.3 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.1 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.2 PID ARF 3PATHWAY Arf1 pathway
0.0 0.0 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.3 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 0.6 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.4 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.4 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.7 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.6 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.3 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.0 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.6 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.2 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.2 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.4 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.1 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.1 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.3 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.5 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 1.0 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.1 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.1 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.3 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.5 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.2 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation