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PRJNA207719: Tissue specific transcriptome profiling
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Results for eomesa
Z-value: 1.44
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Transcription factors associated with eomesa
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| eomesa | dr11_v1_chr19_-_868187_868187 | 0.11 | 8.6e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr15_-_21877726 Show fit | 1.11 |
ENSDART00000127819
ENSDART00000145646 ENSDART00000100897 ENSDART00000144739 |
zgc:162608 |
|
| chr2_-_32637592 Show fit | 1.09 |
ENSDART00000136353
|
si:dkeyp-73d8.8 |
|
| chr10_+_19596214 Show fit | 0.83 |
ENSDART00000183110
|
|
|
| chr7_+_27691647 Show fit | 0.77 |
ENSDART00000079091
|
cytochrome P450, family 2, subfamily R, polypeptide 1 |
|
| chr16_+_23947196 Show fit | 0.73 |
ENSDART00000103190
ENSDART00000132961 ENSDART00000147690 ENSDART00000142168 |
apolipoprotein A-IV b, tandem duplicate 2 |
|
| chr22_+_25352530 Show fit | 0.72 |
ENSDART00000176742
ENSDART00000113186 |
si:dkey-240e12.6 |
|
| chr22_+_25693295 Show fit | 0.72 |
ENSDART00000123888
ENSDART00000150783 |
si:dkeyp-98a7.4 si:dkeyp-98a7.3 |
|
| chr22_+_25715925 Show fit | 0.70 |
ENSDART00000150650
|
si:dkeyp-98a7.7 |
|
| chr20_-_40755614 Show fit | 0.70 |
ENSDART00000061247
|
connexin 32.3 |
|
| chr22_+_25687525 Show fit | 0.69 |
ENSDART00000135717
|
si:dkeyp-98a7.3 |
Network of associatons between targets according to the STRING database.
First level regulatory network of eomesa
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.1 | GO:0010873 | regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873) |
| 0.1 | 0.8 | GO:0071305 | vitamin D3 metabolic process(GO:0070640) cellular response to vitamin D(GO:0071305) |
| 0.0 | 0.5 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.0 | 0.5 | GO:0006208 | pyrimidine nucleobase catabolic process(GO:0006208) |
| 0.0 | 0.5 | GO:0003323 | type B pancreatic cell development(GO:0003323) |
| 0.0 | 0.4 | GO:0007198 | adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198) |
| 0.0 | 0.3 | GO:0009303 | rRNA transcription(GO:0009303) |
| 0.0 | 0.3 | GO:1990399 | sensory epithelium regeneration(GO:0070654) epithelium regeneration(GO:1990399) |
| 0.1 | 0.2 | GO:0055109 | invagination involved in gastrulation with mouth forming second(GO:0055109) morphogenesis of an epithelial fold(GO:0060571) |
| 0.0 | 0.2 | GO:0038107 | nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.1 | GO:0042627 | chylomicron(GO:0042627) |
| 0.0 | 0.3 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 0.0 | 0.2 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.0 | 0.1 | GO:0018444 | translation release factor complex(GO:0018444) |
| 0.0 | 0.1 | GO:0019008 | molybdopterin synthase complex(GO:0019008) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.7 | GO:0030246 | carbohydrate binding(GO:0030246) |
| 0.0 | 1.3 | GO:0015459 | potassium channel regulator activity(GO:0015459) |
| 0.2 | 1.1 | GO:0060228 | phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228) |
| 0.0 | 0.9 | GO:0016712 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712) |
| 0.0 | 0.5 | GO:0004157 | dihydropyrimidinase activity(GO:0004157) |
| 0.0 | 0.5 | GO:0061608 | nuclear import signal receptor activity(GO:0061608) |
| 0.0 | 0.4 | GO:0051378 | amine binding(GO:0043176) serotonin binding(GO:0051378) |
| 0.0 | 0.4 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
| 0.0 | 0.4 | GO:0019003 | GDP binding(GO:0019003) |
| 0.0 | 0.3 | GO:0016803 | ether hydrolase activity(GO:0016803) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.3 | PID FOXO PATHWAY | FoxO family signaling |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.8 | REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
| 0.1 | 0.5 | REACTOME PYRIMIDINE CATABOLISM | Genes involved in Pyrimidine catabolism |
| 0.1 | 0.4 | REACTOME SEROTONIN RECEPTORS | Genes involved in Serotonin receptors |
| 0.0 | 0.2 | REACTOME FGFR1 LIGAND BINDING AND ACTIVATION | Genes involved in FGFR1 ligand binding and activation |