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PRJNA207719: Tissue specific transcriptome profiling
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Results for elf3
Z-value: 1.05
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Transcription factors associated with elf3
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| elf3 | dr11_v1_chr22_+_661711_661711 | 0.85 | 6.5e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr1_+_1904419 Show fit | 0.62 |
ENSDART00000142874
|
si:ch211-132g1.4 |
|
| chr20_+_38285671 Show fit | 0.57 |
ENSDART00000061432
|
chemokine (C-C motif) ligand 38, duplicate 4 |
|
| chr22_+_20710434 Show fit | 0.56 |
ENSDART00000135521
|
PEAK family member 3 |
|
| chr23_-_10175898 Show fit | 0.54 |
ENSDART00000146185
|
keratin 5 |
|
| chr15_+_934660 Show fit | 0.54 |
ENSDART00000154248
|
si:dkey-77f5.10 |
|
| chr9_-_33081781 Show fit | 0.51 |
ENSDART00000165748
|
zgc:172053 |
|
| chr11_-_41084358 Show fit | 0.49 |
ENSDART00000166999
|
zgc:175088 |
|
| chr1_+_1896737 Show fit | 0.47 |
ENSDART00000152442
|
si:ch211-132g1.6 |
|
| chr7_+_35075847 Show fit | 0.46 |
ENSDART00000193469
ENSDART00000037346 |
chymotrypsinogen B1 |
|
| chr3_+_29942338 Show fit | 0.44 |
ENSDART00000158220
|
interferon-induced protein 35 |
Network of associatons between targets according to the STRING database.
First level regulatory network of elf3
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.6 | GO:0048247 | lymphocyte chemotaxis(GO:0048247) |
| 0.0 | 0.5 | GO:0006516 | glycoprotein catabolic process(GO:0006516) |
| 0.1 | 0.4 | GO:0001783 | B cell apoptotic process(GO:0001783) regulation of B cell apoptotic process(GO:0002902) regulation of lymphocyte apoptotic process(GO:0070228) |
| 0.1 | 0.4 | GO:0033499 | galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499) |
| 0.1 | 0.4 | GO:0071233 | response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031) |
| 0.0 | 0.4 | GO:0007080 | mitotic metaphase plate congression(GO:0007080) |
| 0.0 | 0.4 | GO:0071222 | cellular response to molecule of bacterial origin(GO:0071219) cellular response to lipopolysaccharide(GO:0071222) |
| 0.1 | 0.3 | GO:0006929 | substrate-dependent cell migration(GO:0006929) |
| 0.0 | 0.3 | GO:0042554 | superoxide anion generation(GO:0042554) |
| 0.0 | 0.3 | GO:0098787 | mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.7 | GO:0045095 | keratin filament(GO:0045095) |
| 0.1 | 0.4 | GO:0097125 | cyclin B1-CDK1 complex(GO:0097125) |
| 0.1 | 0.4 | GO:0061700 | GATOR2 complex(GO:0061700) |
| 0.0 | 0.3 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
| 0.0 | 0.3 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.0 | 0.3 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
| 0.1 | 0.2 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 0.0 | 0.2 | GO:0070743 | interleukin-12 complex(GO:0043514) interleukin-23 complex(GO:0070743) |
| 0.0 | 0.2 | GO:0000780 | condensed nuclear chromosome kinetochore(GO:0000778) condensed nuclear chromosome, centromeric region(GO:0000780) |
| 0.0 | 0.1 | GO:1902560 | GMP reductase complex(GO:1902560) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.0 | GO:0008009 | chemokine activity(GO:0008009) |
| 0.0 | 0.7 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 0.0 | 0.6 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.1 | 0.5 | GO:1990756 | protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756) |
| 0.0 | 0.5 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.1 | 0.4 | GO:0003978 | UDP-glucose 4-epimerase activity(GO:0003978) |
| 0.1 | 0.4 | GO:0070728 | leucine binding(GO:0070728) |
| 0.0 | 0.3 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 0.0 | 0.3 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.1 | 0.2 | GO:0071532 | ankyrin repeat binding(GO:0071532) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.6 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.0 | 0.6 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.0 | 0.5 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.1 | 0.4 | ST IL 13 PATHWAY | Interleukin 13 (IL-13) Pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.7 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.1 | 0.5 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.0 | 0.4 | REACTOME G2 M DNA DAMAGE CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
| 0.0 | 0.3 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.0 | 0.2 | REACTOME PACKAGING OF TELOMERE ENDS | Genes involved in Packaging Of Telomere Ends |
| 0.0 | 0.2 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 0.0 | 0.2 | REACTOME HYALURONAN METABOLISM | Genes involved in Hyaluronan metabolism |
| 0.0 | 0.1 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.0 | 0.1 | REACTOME TRANSPORT OF ORGANIC ANIONS | Genes involved in Transport of organic anions |
| 0.0 | 0.1 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |