ISMARA results: ehf

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PRJNA207719: Tissue specific transcriptome profiling

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Results for ehf

Z-value: 1.30

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Transcription factors associated with ehf

Gene Symbol	Gene ID	Gene Info
ehf NCBI UniProt	ENSDARG00000052115	ets homologous factor
ehf NCBI UniProt	ENSDARG00000112589	ets homologous factor

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
ehf	dr11_v1_chr25_+_10410620_10410620	0.93	2.1e-02	Click!

Activity profile of ehf motif

Sorted Z-values of ehf motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr9_-_33081978 Show fit	1.28	ENSDART00000100918	zgc:172053 NCBI UniProt Show fit	zgc:172053
chr9_-_33081781 Show fit	1.27	ENSDART00000165748	zgc:172053 NCBI UniProt Show fit	zgc:172053
chr1_-_45177373 Show fit	0.92	ENSDART00000143142 ENSDART00000034549	zgc:111983 NCBI UniProt Show fit	zgc:111983
chr15_-_29598679 Show fit	0.85	ENSDART00000155153	si:ch211-207n23.2 NCBI UniProt Show fit	si:ch211-207n23.2
chr7_+_45975537 Show fit	0.78	ENSDART00000170253	plekhf1 NCBI UniProt Show fit	pleckstrin homology domain containing, family F (with FYVE domain) member 1
chr6_-_49063085 Show fit	0.72	ENSDART00000156124	si:ch211-105j21.9 NCBI UniProt Show fit	si:ch211-105j21.9
chr15_-_29598444 Show fit	0.66	ENSDART00000154847	si:ch211-207n23.2 NCBI UniProt Show fit	si:ch211-207n23.2
chr12_+_38878830 Show fit	0.63	ENSDART00000156926	si:ch211-39f2.3 NCBI UniProt Show fit	si:ch211-39f2.3
chr24_-_6078222 Show fit	0.61	ENSDART00000146830	apbb1ip NCBI UniProt Show fit	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr1_-_69444 Show fit	0.59	ENSDART00000166954	si:zfos-1011f11.1 NCBI UniProt Show fit	si:zfos-1011f11.1

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of ehf

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.3	GO:0016139	glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.1	1.0	GO:0097535	lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.0	1.0	GO:0043297	apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0	0.9	GO:0045324	late endosome to vacuole transport(GO:0045324)
0.1	0.8	GO:0048194	Golgi vesicle budding(GO:0048194)
0.0	0.6	GO:0010737	protein kinase A signaling(GO:0010737)
0.2	0.5	GO:0097237	cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.0	0.5	GO:0000737	DNA catabolic process, endonucleolytic(GO:0000737)
0.0	0.5	GO:0007094	mitotic spindle assembly checkpoint(GO:0007094) spindle checkpoint(GO:0031577) negative regulation of mitotic metaphase/anaphase transition(GO:0045841) spindle assembly checkpoint(GO:0071173) mitotic spindle checkpoint(GO:0071174)
0.0	0.5	GO:0017121	phospholipid scrambling(GO:0017121)

Showing 1 to 10 of 100 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.8	GO:0000815	ESCRT III complex(GO:0000815)
0.0	0.8	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.1	0.7	GO:0097433	dense body(GO:0097433)
0.0	0.6	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.5	GO:0030057	desmosome(GO:0030057)
0.0	0.5	GO:0005732	small nucleolar ribonucleoprotein complex(GO:0005732)
0.0	0.5	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.1	0.4	GO:0098574	cytoplasmic side of lysosomal membrane(GO:0098574)
0.0	0.4	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.4	GO:0031105	septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)

Showing 1 to 10 of 46 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.8	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.2	0.7	GO:0004560	alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.2	0.7	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1	0.7	GO:0098973	structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.1	0.6	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.0	0.6	GO:0042043	neurexin family protein binding(GO:0042043)
0.2	0.5	GO:0004557	alpha-galactosidase activity(GO:0004557)
0.1	0.5	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.1	0.5	GO:0004530	deoxyribonuclease I activity(GO:0004530)
0.1	0.4	GO:0004666	prostaglandin-endoperoxide synthase activity(GO:0004666)

Showing 1 to 10 of 88 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Total log-likelihood	Term	Description
1.1	PID RAC1 PATHWAY	RAC1 signaling pathway
1.0	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.9	PID EPO PATHWAY	EPO signaling pathway
0.5	PID ARF6 PATHWAY	Arf6 signaling events
0.5	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.5	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.3	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.2	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.1	PID FOXO PATHWAY	FoxO family signaling
0.1	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway

Showing 1 to 10 of 13 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.7	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.0	0.6	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	0.6	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.1	0.5	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.0	0.5	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.5	REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C	Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0	0.4	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.4	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	0.4	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.4	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon

Showing 1 to 10 of 27 entries

Results for ehf

Z-value: 1.30

Motif logo

Transcription factors associated with ehf

Activity-expression correlation:

Activity profile of ehf motif

Sorted Z-values of ehf motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of ehf

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: