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PRJNA207719: Tissue specific transcriptome profiling

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Results for egr2a+egr2b

Z-value: 1.78

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Transcription factors associated with egr2a+egr2b

Gene Symbol Gene ID Gene Info
ENSDARG00000042826 early growth response 2b
ENSDARG00000044098 early growth response 2a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
egr2bdr11_v1_chr12_-_8486330_84863300.771.3e-01Click!
egr2adr11_v1_chr17_-_43665366_436653660.484.1e-01Click!

Activity profile of egr2a+egr2b motif

Sorted Z-values of egr2a+egr2b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_22535 3.19 ENSDART00000157877

chr20_-_54462551 2.36 ENSDART00000171769
ENSDART00000169692
Enah/Vasp-like b
chr19_+_342094 1.45 ENSDART00000151013
ENSDART00000187622
endosulfine alpha a
chr12_+_18606140 1.34 ENSDART00000161128
glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein, b
chr23_-_637347 1.23 ENSDART00000132175
L1 cell adhesion molecule, paralog b
chr21_-_43949208 1.20 ENSDART00000150983
calcium/calmodulin-dependent protein kinase II alpha
chr10_-_32851847 1.17 ENSDART00000134255
tripartite motif containing 37
chr11_+_77526 1.15 ENSDART00000193521

chr25_-_12906872 1.12 ENSDART00000165156
ENSDART00000167449
septin 15
chr2_+_47582681 1.10 ENSDART00000187579
secretogranin II (chromogranin C), b
chr11_-_2594045 1.02 ENSDART00000114079
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr8_+_23165749 1.00 ENSDART00000063057
DnaJ (Hsp40) homolog, subfamily C, member 5aa
chr11_+_7324704 0.97 ENSDART00000031937
DIRAS family, GTP-binding RAS-like 1a
chr2_+_47582488 0.97 ENSDART00000149967
secretogranin II (chromogranin C), b
chr4_-_16124417 0.95 ENSDART00000128079
ENSDART00000077664
ATPase plasma membrane Ca2+ transporting 1a
chr7_-_38612230 0.94 ENSDART00000173678
C1q and TNF related 4
chr25_+_34984333 0.90 ENSDART00000154760
coiled-coil domain containing 136b
chr6_-_35446110 0.87 ENSDART00000058773
regulator of G protein signaling 16
chr11_+_1796426 0.85 ENSDART00000173330
low density lipoprotein receptor-related protein 1Aa
chr21_+_28958471 0.83 ENSDART00000144331
ENSDART00000005929
protein phosphatase 3, catalytic subunit, alpha isozyme
chr2_+_59015878 0.83 ENSDART00000148816
ENSDART00000122795
si:ch1073-391i24.1
chr24_+_3963684 0.81 ENSDART00000182959
ENSDART00000185926
ENSDART00000167043
ENSDART00000033394
phosphofructokinase, platelet a
chr25_+_12012 0.81 ENSDART00000170348
contactin 1a
chr24_+_2519761 0.79 ENSDART00000106619
neuritin 1a
chr6_-_15604157 0.77 ENSDART00000141597
leucine rich repeat (in FLII) interacting protein 1b
chr1_-_20271138 0.77 ENSDART00000185931
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr7_-_33023404 0.76 ENSDART00000052383
CD81 molecule a
chr21_+_5169154 0.75 ENSDART00000102559
zgc:122979
chr1_-_22861348 0.74 ENSDART00000139412
si:dkey-92j12.6
chr20_-_53366137 0.74 ENSDART00000146001
WAS protein family, member 1
chr21_-_43952958 0.74 ENSDART00000039571
calcium/calmodulin-dependent protein kinase II alpha
chr5_-_52277643 0.74 ENSDART00000010757
repulsive guidance molecule family member b
chr2_+_38924975 0.73 ENSDART00000109219
RAS (RAD and GEM)-like GTP binding 2
chr23_+_44307996 0.73 ENSDART00000042430
discs, large homolog 4b (Drosophila)
chr16_-_12173399 0.73 ENSDART00000142574
calsyntenin 3
chr17_-_52643970 0.71 ENSDART00000190594
sprouty-related, EVH1 domain containing 1
chr6_-_15604417 0.70 ENSDART00000157817
leucine rich repeat (in FLII) interacting protein 1b
chr15_-_20939579 0.70 ENSDART00000152371
ubiquitin specific peptidase 2a
chr5_-_14390445 0.70 ENSDART00000026120
adaptor-related protein complex 3, mu 2 subunit
chr18_+_18612388 0.70 ENSDART00000186455
ST3 beta-galactoside alpha-2,3-sialyltransferase 2
chr19_+_26340736 0.69 ENSDART00000013497
myosin regulatory light chain interacting protein a
chr15_-_20916251 0.69 ENSDART00000134053
ubiquitin specific peptidase 2a
chr23_+_20422661 0.68 ENSDART00000144047
ENSDART00000104336
troponin C type 2 (fast)
chr25_-_207214 0.67 ENSDART00000193448

chr5_-_26093945 0.66 ENSDART00000010199
ENSDART00000145096
family with sequence similarity 219, member Ab
chr2_-_31936966 0.65 ENSDART00000169484
ENSDART00000192492
ENSDART00000027689
amphiphysin
chr24_-_41478917 0.64 ENSDART00000192192

chr9_+_17348745 0.63 ENSDART00000147488
SLAIN motif family, member 1a
chr16_-_6821927 0.63 ENSDART00000149070
ENSDART00000149570
myelin basic protein b
chr23_+_41799748 0.62 ENSDART00000144257
prodynorphin
chr21_-_23307653 0.61 ENSDART00000140284
ENSDART00000134103
zinc finger and BTB domain containing 16a
chr16_-_12173554 0.61 ENSDART00000110567
ENSDART00000155935
calsyntenin 3
chr17_-_20897250 0.61 ENSDART00000088106
ankyrin 3b
chr3_-_30061985 0.60 ENSDART00000189583
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr8_+_28900689 0.59 ENSDART00000141634
glutamate receptor, ionotropic, delta 2
chr18_-_39702327 0.59 ENSDART00000149158
Dmx-like 2
chr11_-_43137712 0.59 ENSDART00000173089
si:zfos-1837d3.1
chr15_+_1397811 0.58 ENSDART00000102125
schwannomin interacting protein 1
chr6_+_40661703 0.58 ENSDART00000142492
enolase 1b, (alpha)
chr8_+_8298439 0.58 ENSDART00000170566
SRSF protein kinase 3
chr18_+_41495841 0.58 ENSDART00000098671
si:ch211-203b8.6
chr11_+_6819050 0.57 ENSDART00000104289
RAB3A, member RAS oncogene family, b
chr17_-_14726824 0.57 ENSDART00000162947
si:ch73-305o9.3
chr1_-_59176949 0.57 ENSDART00000128742

chr24_+_31334209 0.57 ENSDART00000168837
ENSDART00000172473
family with sequence similarity 168, member B
chr14_+_2243 0.56 ENSDART00000191193
cytokine like 1
chr20_-_28698172 0.56 ENSDART00000190635
signal-induced proliferation-associated 1 like 1
chr13_+_12739283 0.55 ENSDART00000102279
leucine rich repeat and Ig domain containing 2b
chr19_-_31707892 0.55 ENSDART00000088427
RHO family interacting cell polarization regulator 2
chr25_+_20119466 0.55 ENSDART00000104304
2,3-bisphosphoglycerate mutase
chr13_+_36633355 0.54 ENSDART00000135612
si:ch211-67f24.7
chr3_+_35005730 0.54 ENSDART00000029451
protein kinase C, beta b
chr10_+_1668106 0.53 ENSDART00000142278
small G protein signaling modulator 1b
chr24_+_39277043 0.53 ENSDART00000165458
si:ch73-103b11.2
chr4_+_19534833 0.53 ENSDART00000140028
leucine rich repeat containing 4.1
chr1_+_32528097 0.53 ENSDART00000128317
neuroligin 4a
chr3_-_46818001 0.52 ENSDART00000166505
ELAV like neuron-specific RNA binding protein 3
chr11_-_11625369 0.52 ENSDART00000112328
si:dkey-28e7.3
chr7_+_30867008 0.52 ENSDART00000193106
amyloid beta (A4) precursor protein-binding, family A, member 2b
chr3_+_40315410 0.52 ENSDART00000083241
ENSDART00000132827
solute carrier family 29 (equilibrative nucleoside transporter), member 4
chr8_+_24854600 0.51 ENSDART00000156570
solute carrier family 6 (neutral amino acid transporter), member 17
chr5_+_31283576 0.50 ENSDART00000133743
calcium/calmodulin-dependent protein kinase kinase 1, alpha a
chr20_-_915234 0.50 ENSDART00000164816
cannabinoid receptor 1
chr5_-_23517747 0.50 ENSDART00000137655
stromal antigen 2a
chr3_-_46817499 0.50 ENSDART00000013717
ELAV like neuron-specific RNA binding protein 3
chr2_-_155270 0.49 ENSDART00000131177
adenylate cyclase 1b
chr3_-_46817838 0.49 ENSDART00000028610
ELAV like neuron-specific RNA binding protein 3
chr8_-_4618653 0.48 ENSDART00000025535
septin 5a
chr21_+_7900107 0.48 ENSDART00000056560
cholesterol 25-hydroxylase like 2
chr19_-_25113660 0.48 ENSDART00000035538
protein tyrosine phosphatase type IVA, member 3
chr14_-_2933185 0.48 ENSDART00000161677
ENSDART00000162446
ENSDART00000109378
si:dkey-201i24.6
chr18_+_402048 0.47 ENSDART00000166345
glucose-6-phosphate isomerase b
chr20_+_27298783 0.47 ENSDART00000013861
protein phosphatase 4, regulatory subunit 4
chr24_-_39354829 0.47 ENSDART00000169108
potassium inwardly-rectifying channel, subfamily J, member 12a
chr7_-_52849913 0.47 ENSDART00000174133
ENSDART00000172951
microtubule-associated protein 1Aa
chr25_-_7999756 0.46 ENSDART00000159908
calcium/calmodulin-dependent protein kinase 1Db
chr5_+_72377851 0.46 ENSDART00000160479
lectin, mannose-binding 2-like a
chr12_-_13886952 0.45 ENSDART00000110503
ADAM metallopeptidase domain 11
chr23_+_16633951 0.45 ENSDART00000109537
ENSDART00000193323
syntaphilin b
chr15_+_42397125 0.45 ENSDART00000169751
T cell lymphoma invasion and metastasis 1b
chr25_+_1304173 0.45 ENSDART00000155229
relaxin/insulin-like family peptide receptor 3.3b
chr22_+_4707663 0.45 ENSDART00000042194
ceramide synthase 4a
chr3_-_61185746 0.45 ENSDART00000028219
parvalbumin 4
chr19_+_5480327 0.45 ENSDART00000148794
junction plakoglobin b
chr20_-_45661049 0.44 ENSDART00000124582
ENSDART00000131251
N-ethylmaleimide-sensitive factor attachment protein, beta b
chr9_+_32428679 0.44 ENSDART00000187650
ENSDART00000190472
phospholipase C like 1
chr5_+_65492183 0.44 ENSDART00000162804
si:dkey-21e5.1
chr14_-_23799345 0.44 ENSDART00000124144
ENSDART00000181179
ENSDART00000124401
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr4_+_2619132 0.44 ENSDART00000128807
G protein-coupled receptor 22a
chr12_+_19036380 0.43 ENSDART00000153086
ENSDART00000181060
potassium channel tetramerization domain containing 17
chr10_-_15919839 0.43 ENSDART00000065032
phosphatidylinositol-4-phosphate 5-kinase, type I, beta a
chr10_+_2232023 0.43 ENSDART00000097695
contactin associated protein like 3
chr13_-_21739142 0.43 ENSDART00000078460
si:dkey-191g9.5
chr20_+_710052 0.43 ENSDART00000166656
SUMO1/sentrin specific peptidase 6a
chr11_-_11625630 0.43 ENSDART00000161821
ENSDART00000193152
si:dkey-28e7.3
chr7_+_31051213 0.43 ENSDART00000148347
tight junction protein 1a
chr12_-_20303438 0.43 ENSDART00000153057
rhomboid 5 homolog 1b (Drosophila)
chr19_-_867071 0.42 ENSDART00000122257
eomesodermin homolog a
chr10_+_26571174 0.42 ENSDART00000148617
ENSDART00000112956
solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6b
chr17_+_890988 0.42 ENSDART00000186843

chr25_-_29134654 0.42 ENSDART00000067066
poly (ADP-ribose) polymerase family, member 6b
chr7_-_26408472 0.41 ENSDART00000111494
galactose-3-O-sulfotransferase 4
chr15_-_47193564 0.41 ENSDART00000172453
limbic system-associated membrane protein
chr10_+_15777064 0.41 ENSDART00000114483
amyloid beta (A4) precursor protein-binding, family A, member 1b
chr5_+_31820264 0.40 ENSDART00000110974
zinc finger, DHHC-type containing 12b
chr1_+_54673846 0.40 ENSDART00000145018
G protein-coupled receptor, class C, group 5, member Bb
chr5_+_483965 0.40 ENSDART00000150007
TEK tyrosine kinase, endothelial
chr18_+_3169579 0.40 ENSDART00000164724
ENSDART00000186340
ENSDART00000181247
ENSDART00000168056
p21 protein (Cdc42/Rac)-activated kinase 1
chr2_-_7431590 0.40 ENSDART00000185699
agouti signaling protein, nonagouti homolog (mouse) 2b
chr25_-_19395476 0.39 ENSDART00000182622
microtubule-associated protein 1Ab
chr22_-_3564563 0.39 ENSDART00000145114
protein tyrosine phosphatase, receptor type, s, a
chr23_-_32156278 0.39 ENSDART00000157479
nuclear receptor subfamily 4, group A, member 1
chr15_-_23342752 0.39 ENSDART00000020425
melanoma cell adhesion molecule b
chr5_-_21030934 0.39 ENSDART00000133461
ENSDART00000098667
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1
chr3_-_6767440 0.39 ENSDART00000156174
microtubule associated serine/threonine kinase 1b
chr5_-_46273938 0.39 ENSDART00000080033
si:ch211-130m23.3
chr25_+_34888886 0.38 ENSDART00000035245
spire-type actin nucleation factor 2
chr11_-_426525 0.38 ENSDART00000157054
zinc finger protein 831
chr22_-_21676364 0.38 ENSDART00000183668
transducin like enhancer of split 2b
chr24_-_17892325 0.37 ENSDART00000154039
ENSDART00000185619
ENSDART00000178326
contactin associated protein like 2a
chr5_-_21524251 0.37 ENSDART00000176793
ENSDART00000040184
teneurin transmembrane protein 1
chr1_+_44941031 0.37 ENSDART00000141145
si:dkey-9i23.16
chr5_-_1999417 0.36 ENSDART00000155437
ENSDART00000145781
si:ch211-160e1.5
chr12_-_212843 0.36 ENSDART00000083574

chr13_+_25428677 0.36 ENSDART00000186284
si:dkey-51a16.9
chr3_-_30685401 0.35 ENSDART00000151097
si:ch211-51c14.1
chr15_-_5467477 0.35 ENSDART00000123839
arrestin, beta 1
chr3_-_28075756 0.35 ENSDART00000122037
RNA binding fox-1 homolog 1
chr25_-_10564721 0.35 ENSDART00000154776
galanin/GMAP prepropeptide
chr1_-_7917062 0.35 ENSDART00000177068
monocyte to macrophage differentiation-associated 2b
chr9_-_54001502 0.35 ENSDART00000085253
midline 1
chr11_+_30161168 0.35 ENSDART00000157385
cyclin-dependent kinase-like 5
chr16_-_22775480 0.35 ENSDART00000141778
ENSDART00000145585
ENSDART00000125963
ENSDART00000127570
pre-B-cell leukemia homeobox interacting protein 1b
chr7_-_20611039 0.35 ENSDART00000170422
si:dkey-19b23.8
chr5_-_42180205 0.34 ENSDART00000145247
family with sequence similarity 222, member Ba
chr7_-_18601206 0.34 ENSDART00000111636
si:ch211-119e14.2
chr14_+_49462855 0.34 ENSDART00000167713
ENSDART00000164692
ENSDART00000036462
dynactin 4
chr13_+_31144305 0.34 ENSDART00000189602

chr6_+_42819337 0.34 ENSDART00000046498
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa
chr1_-_7659870 0.34 ENSDART00000085203
ephrin-B2b
chr18_-_12327426 0.33 ENSDART00000136992
ENSDART00000114024
family with sequence similarity 107, member B
chr5_-_40510397 0.33 ENSDART00000146237
ENSDART00000051065
follistatin a
chr6_+_52263236 0.33 ENSDART00000144174
extended synaptotagmin-like protein 1b
chr18_-_16179129 0.33 ENSDART00000125353
solute carrier family 6 (neutral amino acid transporter), member 15
chr9_-_41401564 0.33 ENSDART00000059628
NGFI-A binding protein 1b (EGR1 binding protein 1)
chr1_+_604127 0.33 ENSDART00000133165
junctional adhesion molecule 2a
chr12_+_49125510 0.32 ENSDART00000185804

chr9_-_24046287 0.32 ENSDART00000184313
atypical chemokine receptor 3a
chr22_-_18746508 0.32 ENSDART00000003929
midnolin
chr10_+_110868 0.32 ENSDART00000135572
ENSDART00000190467
ENSDART00000056672
phosphatidylinositol glycan anchor biosynthesis, class P
chr22_-_12693833 0.32 ENSDART00000129768
ENSDART00000044574
adenosine deaminase, RNA-specific, B1a
chr1_-_59417949 0.32 ENSDART00000170558
si:ch211-188p14.3
chr10_+_2234283 0.32 ENSDART00000136363
contactin associated protein like 3
chr17_+_12698532 0.31 ENSDART00000064509
ENSDART00000136830
stathmin-like 4, like
chr11_-_43226255 0.31 ENSDART00000172929
spectrin, beta, non-erythrocytic 1
chr4_-_9173552 0.31 ENSDART00000042963
carbohydrate (chondroitin 4) sulfotransferase 11
chr17_+_30587333 0.31 ENSDART00000156500
NHS-like 1a
chr7_-_69636502 0.31 ENSDART00000126739
tetraspanin 5a
chr5_+_32791245 0.31 ENSDART00000077189
immediate early response 5-like
chr14_-_21218891 0.30 ENSDART00000158294
protein phosphatase 2, regulatory subunit B, gamma b
chr16_+_11151699 0.30 ENSDART00000140674
capicua transcriptional repressor b
chr11_-_24191928 0.30 ENSDART00000136827
SRY (sex determining region Y)-box 12
chr13_+_51853716 0.30 ENSDART00000175341
ENSDART00000187855

chr20_-_26624042 0.30 ENSDART00000077962
exocyst complex component 2
chr20_+_27087539 0.30 ENSDART00000062094
transmembrane protein 251
chr25_+_27493444 0.30 ENSDART00000112299
G protein-coupled receptor 37a
chr12_+_26621906 0.30 ENSDART00000158440
ENSDART00000046959
Rho GTPase activating protein 12b
chr22_+_18786797 0.30 ENSDART00000141864
calcium channel, voltage-dependent, beta subunit associated regulatory protein b
chr20_-_14665002 0.30 ENSDART00000152816
secernin 2
chr6_+_21740672 0.30 ENSDART00000193734
lipoma HMGIC fusion partner-like 4a
chr2_+_8112449 0.29 ENSDART00000138136
carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2a
chr2_+_37480669 0.29 ENSDART00000029801
signal peptide peptidase-like 2
chr14_+_7939398 0.29 ENSDART00000189773
CXXC finger protein 5b
chr20_-_14781904 0.29 ENSDART00000187200
ENSDART00000179912
ENSDART00000160481
ENSDART00000026969
SUN domain containing ossification factor
chr19_+_2602903 0.29 ENSDART00000033132
family with sequence similarity 126, member A
chr2_-_48966431 0.29 ENSDART00000147948
potassium inwardly-rectifying channel, subfamily J, member 9
chr17_-_42213285 0.29 ENSDART00000140549
NK2 homeobox 2a
chr5_-_64431927 0.29 ENSDART00000158248
bromodomain containing 3b
chr9_+_38369872 0.29 ENSDART00000193914
phospholipase C, delta 4b
chr25_+_34889061 0.29 ENSDART00000136226
spire-type actin nucleation factor 2

Network of associatons between targets according to the STRING database.

First level regulatory network of egr2a+egr2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.2 0.6 GO:1901546 regulation of cellular pH reduction(GO:0032847) synaptic vesicle lumen acidification(GO:0097401) regulation of synaptic vesicle lumen acidification(GO:1901546)
0.2 1.2 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.2 1.0 GO:0061551 trigeminal ganglion development(GO:0061551)
0.2 0.6 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.2 1.0 GO:0034505 tooth mineralization(GO:0034505)
0.2 0.5 GO:2000402 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869) negative regulation of lymphocyte migration(GO:2000402) negative regulation of T cell migration(GO:2000405)
0.2 0.7 GO:0060300 regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.2 1.0 GO:0072578 neurotransmitter-gated ion channel clustering(GO:0072578)
0.2 1.2 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 1.3 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 0.4 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.1 0.4 GO:0060571 invagination involved in gastrulation with mouth forming second(GO:0055109) morphogenesis of an epithelial fold(GO:0060571)
0.1 0.4 GO:0032369 negative regulation of lipid transport(GO:0032369)
0.1 0.7 GO:0010801 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.1 0.6 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.1 0.4 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.1 0.4 GO:0071387 cellular response to cortisol stimulus(GO:0071387) response to dexamethasone(GO:0071548)
0.1 0.4 GO:0090234 regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
0.1 0.3 GO:0032060 bleb assembly(GO:0032060) slow muscle cell migration(GO:1904969)
0.1 0.5 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.1 0.4 GO:0002159 desmosome assembly(GO:0002159)
0.1 2.4 GO:0051289 protein homotetramerization(GO:0051289)
0.1 0.7 GO:0033206 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.1 0.2 GO:0021530 spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.1 1.6 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 0.4 GO:0099612 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.1 0.8 GO:0061718 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 0.6 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.1 0.5 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 0.8 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.9 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.1 0.3 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 2.0 GO:0035308 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.1 0.4 GO:0003232 bulbus arteriosus development(GO:0003232)
0.1 0.3 GO:1904357 negative regulation of telomere maintenance via telomerase(GO:0032211) negative regulation of telomere maintenance via telomere lengthening(GO:1904357)
0.1 0.2 GO:0010662 negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.1 0.2 GO:0048785 hatching gland development(GO:0048785)
0.1 0.3 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.1 0.4 GO:0010595 positive regulation of endothelial cell migration(GO:0010595)
0.1 0.3 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.1 0.8 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 0.2 GO:0021828 substrate-dependent cell migration(GO:0006929) pallium development(GO:0021543) cerebral cortex cell migration(GO:0021795) cerebral cortex tangential migration(GO:0021800) cerebral cortex tangential migration using cell-axon interactions(GO:0021824) substrate-dependent cerebral cortex tangential migration(GO:0021825) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) cerebral cortex development(GO:0021987)
0.1 1.5 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 0.2 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520) monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.5 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.4 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.0 0.6 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.0 1.8 GO:1903670 regulation of sprouting angiogenesis(GO:1903670)
0.0 0.4 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.3 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955) negative regulation of regulated secretory pathway(GO:1903306)
0.0 0.2 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.0 0.1 GO:0006505 GPI anchor metabolic process(GO:0006505)
0.0 0.3 GO:0098815 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.0 0.4 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 1.0 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.0 0.6 GO:0021988 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 0.5 GO:0016199 axon midline choice point recognition(GO:0016199)
0.0 0.5 GO:1901642 nucleoside transport(GO:0015858) nucleoside transmembrane transport(GO:1901642)
0.0 0.7 GO:0014823 response to activity(GO:0014823)
0.0 0.2 GO:0043363 nucleate erythrocyte differentiation(GO:0043363)
0.0 0.6 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.5 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.1 GO:0030091 protein repair(GO:0030091)
0.0 0.4 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.2 GO:0031112 positive regulation of microtubule polymerization or depolymerization(GO:0031112) positive regulation of microtubule polymerization(GO:0031116)
0.0 0.3 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.3 GO:1904103 regulation of convergent extension involved in gastrulation(GO:1904103)
0.0 0.3 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.3 GO:0046850 regulation of bone remodeling(GO:0046850)
0.0 0.1 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.0 0.3 GO:0039023 pronephric duct morphogenesis(GO:0039023)
0.0 0.2 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.0 0.1 GO:0055071 manganese ion homeostasis(GO:0055071)
0.0 0.3 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.4 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
0.0 0.7 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 1.4 GO:0003146 heart jogging(GO:0003146)
0.0 0.1 GO:0070650 actin filament bundle distribution(GO:0070650)
0.0 0.1 GO:0097272 ammonia homeostasis(GO:0097272)
0.0 0.3 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.2 GO:0030859 polarized epithelial cell differentiation(GO:0030859)
0.0 0.1 GO:0097037 heme export(GO:0097037)
0.0 0.6 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.0 0.1 GO:0006212 uracil catabolic process(GO:0006212) beta-alanine metabolic process(GO:0019482) beta-alanine biosynthetic process(GO:0019483) uracil metabolic process(GO:0019860) 'de novo' UMP biosynthetic process(GO:0044205)
0.0 0.3 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.2 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 0.4 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.2 GO:0098900 regulation of action potential(GO:0098900)
0.0 0.4 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 0.1 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.2 GO:0007584 response to nutrient(GO:0007584)
0.0 0.4 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.5 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.2 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.3 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.9 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 0.2 GO:0021754 facial nucleus development(GO:0021754)
0.0 0.2 GO:0032264 IMP salvage(GO:0032264)
0.0 0.1 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.2 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.3 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.1 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.0 0.3 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.1 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 1.8 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.2 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.0 0.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.2 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.4 GO:0043409 negative regulation of MAPK cascade(GO:0043409)
0.0 0.2 GO:0060034 notochord cell differentiation(GO:0060034)
0.0 0.2 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.2 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:0031284 regulation of cGMP metabolic process(GO:0030823) positive regulation of cGMP metabolic process(GO:0030825) regulation of cGMP biosynthetic process(GO:0030826) positive regulation of cGMP biosynthetic process(GO:0030828) regulation of guanylate cyclase activity(GO:0031282) positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.6 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.2 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.3 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.2 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.6 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.4 GO:0016180 snRNA processing(GO:0016180)
0.0 0.4 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.4 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.5 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.0 0.5 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.6 GO:0009247 glycolipid biosynthetic process(GO:0009247)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0005955 calcineurin complex(GO:0005955)
0.2 1.2 GO:0016234 inclusion body(GO:0016234)
0.1 0.6 GO:0043291 RAVE complex(GO:0043291)
0.1 1.7 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.5 GO:0060171 stereocilium membrane(GO:0060171)
0.1 0.3 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 0.4 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.3 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.3 GO:1990879 CST complex(GO:1990879)
0.1 0.8 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 0.3 GO:0098553 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 0.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.2 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.1 0.3 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 0.4 GO:0070062 extracellular exosome(GO:0070062)
0.1 0.3 GO:0008091 spectrin(GO:0008091)
0.1 0.2 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.4 GO:0033010 paranodal junction(GO:0033010)
0.0 0.2 GO:0097433 dense body(GO:0097433)
0.0 1.7 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.6 GO:0043209 myelin sheath(GO:0043209)
0.0 2.3 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.2 GO:0043034 costamere(GO:0043034)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0035517 PR-DUB complex(GO:0035517)
0.0 2.3 GO:0030141 secretory granule(GO:0030141)
0.0 0.8 GO:0043679 axon terminus(GO:0043679)
0.0 0.7 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.7 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.2 GO:0043194 axon initial segment(GO:0043194)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.4 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.3 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 2.0 GO:0030027 lamellipodium(GO:0030027)
0.0 0.3 GO:0005869 dynactin complex(GO:0005869)
0.0 0.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.7 GO:0005861 troponin complex(GO:0005861)
0.0 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.9 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 3.5 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 1.2 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.8 GO:1903293 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.4 GO:0016528 sarcoplasm(GO:0016528) sarcoplasmic reticulum(GO:0016529)
0.0 0.3 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.6 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.0 GO:0097255 R2TP complex(GO:0097255)
0.0 0.2 GO:1990907 beta-catenin-TCF complex(GO:1990907)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.4 GO:0005522 profilin binding(GO:0005522)
0.2 0.8 GO:0071889 14-3-3 protein binding(GO:0071889)
0.2 1.1 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.5 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 0.4 GO:0031701 angiotensin receptor binding(GO:0031701)
0.1 1.6 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.1 0.7 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.5 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.1 0.8 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.4 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.1 0.5 GO:0035173 histone kinase activity(GO:0035173)
0.1 0.8 GO:0003872 6-phosphofructokinase activity(GO:0003872) fructose-6-phosphate binding(GO:0070095)
0.1 0.4 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 0.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.2 GO:0043621 protein self-association(GO:0043621)
0.1 0.2 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.1 0.5 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.1 0.3 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.1 0.3 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.1 0.3 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 0.5 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.1 0.8 GO:0031628 opioid receptor binding(GO:0031628)
0.1 0.3 GO:0039706 co-receptor binding(GO:0039706)
0.1 0.3 GO:0070052 collagen V binding(GO:0070052)
0.1 0.3 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.1 0.3 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 1.1 GO:0015026 coreceptor activity(GO:0015026)
0.1 0.3 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.1 2.6 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 0.4 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 0.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.5 GO:0015385 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.4 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.3 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.2 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.0 0.3 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.6 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.0 1.2 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.2 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.0 0.3 GO:0035255 GKAP/Homer scaffold activity(GO:0030160) ionotropic glutamate receptor binding(GO:0035255)
0.0 0.2 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.0 0.9 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.2 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.7 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.3 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.5 GO:0005537 mannose binding(GO:0005537)
0.0 0.5 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.4 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.4 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.4 GO:0038191 neuropilin binding(GO:0038191)
0.0 1.0 GO:0019003 GDP binding(GO:0019003)
0.0 1.0 GO:0051087 chaperone binding(GO:0051087)
0.0 0.1 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.1 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.1 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.1 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.0 0.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.5 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.6 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 1.2 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.3 GO:0016208 AMP binding(GO:0016208)
0.0 0.5 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.3 GO:0048185 activin binding(GO:0048185)
0.0 0.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 2.0 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.7 GO:0017022 myosin binding(GO:0017022)
0.0 0.1 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.3 GO:0002039 p53 binding(GO:0002039)
0.0 0.3 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.4 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 0.2 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.1 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.0 0.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.5 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.4 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 0.4 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.3 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 0.8 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.1 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.3 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.2 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 1.0 PID BMP PATHWAY BMP receptor signaling
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.4 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.5 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.1 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.7 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.7 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.1 ST ADRENERGIC Adrenergic Pathway
0.0 0.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.6 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.4 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.3 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.1 0.7 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 0.4 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 0.8 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.8 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.3 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.6 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.3 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.7 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.6 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.1 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.7 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.5 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.2 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.0 REACTOME SIGNALING BY ERBB4 Genes involved in Signaling by ERBB4
0.0 0.1 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.4 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.1 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.1 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1