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PRJNA207719: Tissue specific transcriptome profiling
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Results for ebf1b
Z-value: 1.16
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Transcription factors associated with ebf1b
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ebf1b | dr11_v1_chr21_-_33851877_33851877 | 0.80 | 1.1e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr20_+_34933183 Show fit | 1.44 |
ENSDART00000062738
|
synaptosomal-associated protein, 25a |
|
| chr1_-_44701313 Show fit | 1.38 |
ENSDART00000193926
|
si:dkey-28b4.8 |
|
| chr12_-_35787801 Show fit | 1.34 |
ENSDART00000171682
|
apoptosis-associated tyrosine kinase b |
|
| chr21_-_19018455 Show fit | 1.03 |
ENSDART00000080256
|
neurofilament, medium polypeptide a |
|
| chr5_-_37933983 Show fit | 1.02 |
ENSDART00000185364
|
sodium channel, voltage-gated, type IV, beta b |
|
| chr10_+_19554604 Show fit | 0.98 |
ENSDART00000063806
|
ATPase H+ transporting V1 subunit B2 |
|
| chr4_+_11375894 Show fit | 0.94 |
ENSDART00000190471
ENSDART00000143963 |
piccolo presynaptic cytomatrix protein a |
|
| chr19_-_13733870 Show fit | 0.93 |
ENSDART00000177773
|
erythrocyte membrane protein band 4.1a |
|
| chr19_-_26863626 Show fit | 0.88 |
ENSDART00000145568
|
proline-rich transmembrane protein 1 |
|
| chr18_-_19095141 Show fit | 0.84 |
ENSDART00000090962
ENSDART00000090922 |
DENN/MADD domain containing 4A |
Network of associatons between targets according to the STRING database.
First level regulatory network of ebf1b
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.4 | GO:0070588 | calcium ion transmembrane transport(GO:0070588) |
| 0.0 | 1.4 | GO:0016082 | synaptic vesicle priming(GO:0016082) |
| 0.2 | 1.3 | GO:0038083 | peptidyl-tyrosine autophosphorylation(GO:0038083) |
| 0.0 | 1.2 | GO:1902600 | hydrogen ion transmembrane transport(GO:1902600) |
| 0.0 | 1.1 | GO:0007218 | neuropeptide signaling pathway(GO:0007218) |
| 0.3 | 1.0 | GO:0071361 | cellular response to ethanol(GO:0071361) |
| 0.2 | 1.0 | GO:0060052 | neurofilament cytoskeleton organization(GO:0060052) |
| 0.1 | 0.9 | GO:1904071 | presynaptic active zone assembly(GO:1904071) |
| 0.0 | 0.9 | GO:0030866 | cortical actin cytoskeleton organization(GO:0030866) |
| 0.1 | 0.8 | GO:0032483 | regulation of Rab protein signal transduction(GO:0032483) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.6 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.2 | 1.4 | GO:0070032 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) |
| 0.1 | 1.4 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.0 | 1.2 | GO:0030427 | site of polarized growth(GO:0030427) |
| 0.2 | 1.0 | GO:0005883 | neurofilament(GO:0005883) |
| 0.1 | 1.0 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
| 0.0 | 1.0 | GO:0043204 | perikaryon(GO:0043204) |
| 0.1 | 0.9 | GO:0098982 | GABA-ergic synapse(GO:0098982) |
| 0.0 | 0.7 | GO:0043679 | axon terminus(GO:0043679) |
| 0.0 | 0.5 | GO:0005844 | polysome(GO:0005844) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.6 | GO:0005245 | voltage-gated calcium channel activity(GO:0005245) |
| 0.1 | 1.4 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
| 0.0 | 1.4 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.1 | 1.0 | GO:0016934 | extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934) |
| 0.0 | 1.0 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
| 0.1 | 0.9 | GO:0098882 | structural constituent of presynaptic active zone(GO:0098882) |
| 0.1 | 0.7 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
| 0.0 | 0.6 | GO:0031628 | opioid receptor binding(GO:0031628) |
| 0.0 | 0.6 | GO:0072542 | phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542) |
| 0.0 | 0.6 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | PID CERAMIDE PATHWAY | Ceramide signaling pathway |
| 0.0 | 0.3 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
| 0.0 | 0.2 | PID S1P S1P4 PATHWAY | S1P4 pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.0 | REACTOME INSULIN RECEPTOR RECYCLING | Genes involved in Insulin receptor recycling |
| 0.0 | 1.0 | REACTOME LIGAND GATED ION CHANNEL TRANSPORT | Genes involved in Ligand-gated ion channel transport |
| 0.0 | 0.5 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.0 | 0.4 | REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.0 | 0.4 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.0 | 0.4 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.0 | 0.3 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.1 | 0.2 | REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING | Genes involved in Role of second messengers in netrin-1 signaling |
| 0.0 | 0.2 | REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
| 0.0 | 0.2 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |