ISMARA results: e2f3

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PRJNA207719: Tissue specific transcriptome profiling

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Results for e2f3

Z-value: 0.37

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Transcription factors associated with e2f3

Gene Symbol	Gene ID	Gene Info
e2f3 NCBI UniProt	ENSDARG00000070463	E2F transcription factor 3

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
e2f3	dr11_v1_chr19_-_29294457_29294457	0.09	8.9e-01	Click!

Activity profile of e2f3 motif

Sorted Z-values of e2f3 motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr14_+_904850 Show fit	0.64	ENSDART00000161847	si:ch73-208h1.1 NCBI UniProt Show fit	si:ch73-208h1.1
chr16_-_25085327 Show fit	0.44	ENSDART00000077661	prss1 NCBI UniProt Show fit	protease, serine 1
chr25_+_186583 Show fit	0.39	ENSDART00000161504	pclaf NCBI UniProt Show fit	PCNA clamp associated factor
chr9_-_2892045 Show fit	0.34	ENSDART00000137201	cdca7a NCBI UniProt Show fit	cell division cycle associated 7a
chr9_-_2892250 Show fit	0.31	ENSDART00000140695	cdca7a NCBI UniProt Show fit	cell division cycle associated 7a
chr15_-_2954443 Show fit	0.28	ENSDART00000161053	zgc:153184 NCBI UniProt Show fit	zgc:153184
chr21_-_26490186 Show fit	0.23	ENSDART00000009889	zgc:110540 NCBI UniProt Show fit	zgc:110540
chr2_-_44344321 Show fit	0.22	ENSDART00000084174	lig1 NCBI UniProt Show fit	ligase I, DNA, ATP-dependent
chr20_-_44090624 Show fit	0.14	ENSDART00000048978 ENSDART00000082283 ENSDART00000082276	runx2b NCBI UniProt Show fit	runt-related transcription factor 2b
chr3_-_32275975 Show fit	0.14	ENSDART00000178448	cpt1cb NCBI UniProt Show fit	carnitine palmitoyltransferase 1Cb

Showing 1 to 10 of 53 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of e2f3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Total log-likelihood	Term	Description
0.6	GO:0048538	thymus development(GO:0048538)
0.4	GO:0019985	translesion synthesis(GO:0019985)
0.2	GO:0051103	DNA ligation(GO:0006266) DNA ligation involved in DNA repair(GO:0051103)
0.1	GO:0015878	biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.1	GO:0043111	replication fork arrest(GO:0043111)
0.1	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.1	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1	GO:0032776	DNA methylation on cytosine(GO:0032776)
0.0	GO:0007571	age-dependent general metabolic decline(GO:0007571)

Showing 1 to 9 of 9 entries

Gene overrepresentation in cellular component category:

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Total log-likelihood	Term	Description
0.1	GO:0031511	Mis6-Sim4 complex(GO:0031511)
0.1	GO:0031298	replication fork protection complex(GO:0031298)
0.1	GO:0097134	cyclin E1-CDK2 complex(GO:0097134)
0.0	GO:0000333	telomerase catalytic core complex(GO:0000333)

Showing 1 to 4 of 4 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0003909	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	0.2	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.1	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	0.1	GO:0008523	sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.0	0.0	GO:0003721	telomerase RNA reverse transcriptase activity(GO:0003721)

Showing 1 to 5 of 5 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.2	REACTOME EARLY PHASE OF HIV LIFE CYCLE	Genes involved in Early Phase of HIV Life Cycle
0.0	0.2	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex

Showing 1 to 3 of 3 entries

Results for e2f3

Z-value: 0.37

Motif logo

Transcription factors associated with e2f3

Activity-expression correlation:

Activity profile of e2f3 motif

Sorted Z-values of e2f3 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of e2f3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: