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PRJNA207719: Tissue specific transcriptome profiling
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Results for drgx_arxb
Z-value: 0.72
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Transcription factors associated with drgx_arxb
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| arxb | dr11_v1_chr21_-_40676224_40676224 | 0.89 | 4.2e-02 | Click! |
| drgx | dr11_v1_chr13_+_30912117_30912117 | 0.62 | 2.6e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr4_+_9669717 Show fit | 1.47 |
ENSDART00000004604
|
si:dkey-153k10.9 |
|
| chr21_-_27881752 Show fit | 1.14 |
ENSDART00000132583
|
neurexin 2a |
|
| chr24_-_38079261 Show fit | 1.05 |
ENSDART00000105662
|
C-reactive protein 1 |
|
| chr25_-_13381854 Show fit | 1.04 |
ENSDART00000164621
ENSDART00000169129 |
NDRG family member 4 |
|
| chr4_-_14315855 Show fit | 1.02 |
ENSDART00000133325
|
neural EGFL like 2b |
|
| chr24_-_38384432 Show fit | 0.96 |
ENSDART00000140739
|
leucine rich repeat containing 4Bb |
|
| chr21_+_7582036 Show fit | 0.94 |
ENSDART00000135485
ENSDART00000027268 |
orthopedia homeobox a |
|
| chr7_+_26629084 Show fit | 0.86 |
ENSDART00000101044
ENSDART00000173765 |
heat shock factor binding protein 1a |
|
| chr8_-_7391721 Show fit | 0.82 |
ENSDART00000149836
|
LHFPL tetraspan subfamily member 4b |
|
| chr18_+_1703984 Show fit | 0.80 |
ENSDART00000114010
|
SLIT and NTRK-like family, member 3a |
Network of associatons between targets according to the STRING database.
First level regulatory network of drgx_arxb
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.3 | GO:0008045 | motor neuron axon guidance(GO:0008045) |
| 0.1 | 1.0 | GO:0045162 | clustering of voltage-gated sodium channels(GO:0045162) |
| 0.2 | 0.9 | GO:0051703 | mammillary body development(GO:0021767) social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703) |
| 0.1 | 0.9 | GO:0034605 | cellular response to heat(GO:0034605) |
| 0.0 | 0.7 | GO:0072114 | pronephros morphogenesis(GO:0072114) |
| 0.2 | 0.6 | GO:1900620 | acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620) |
| 0.1 | 0.5 | GO:0021877 | forebrain neuron fate commitment(GO:0021877) |
| 0.0 | 0.5 | GO:0035269 | protein O-linked mannosylation(GO:0035269) |
| 0.0 | 0.5 | GO:0006198 | cAMP catabolic process(GO:0006198) |
| 0.0 | 0.5 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.4 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 0.1 | 0.3 | GO:0098842 | postsynaptic early endosome(GO:0098842) |
| 0.0 | 0.3 | GO:0005854 | nascent polypeptide-associated complex(GO:0005854) |
| 0.0 | 0.2 | GO:0031045 | dense core granule(GO:0031045) |
| 0.0 | 0.1 | GO:0071818 | BAT3 complex(GO:0071818) |
| 0.0 | 0.1 | GO:0060171 | stereocilium membrane(GO:0060171) |
| 0.0 | 0.1 | GO:1990513 | CLOCK-BMAL transcription complex(GO:1990513) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.3 | GO:0005080 | protein kinase C binding(GO:0005080) |
| 0.0 | 0.7 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
| 0.0 | 0.6 | GO:0016413 | O-acetyltransferase activity(GO:0016413) |
| 0.0 | 0.5 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
| 0.0 | 0.5 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
| 0.0 | 0.5 | GO:0008374 | O-acyltransferase activity(GO:0008374) |
| 0.1 | 0.4 | GO:0031005 | filamin binding(GO:0031005) |
| 0.1 | 0.4 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 0.0 | 0.4 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
| 0.0 | 0.4 | GO:0045159 | myosin II binding(GO:0045159) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.5 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.0 | 0.3 | PID EPHA2 FWD PATHWAY | EPHA2 forward signaling |
| 0.0 | 0.2 | PID NFKAPPAB ATYPICAL PATHWAY | Atypical NF-kappaB pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS | Genes involved in Trafficking of GluR2-containing AMPA receptors |
| 0.0 | 0.2 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.0 | 0.1 | REACTOME SEMA3A PAK DEPENDENT AXON REPULSION | Genes involved in Sema3A PAK dependent Axon repulsion |