ISMARA results: dmbx1a+dmbx1b

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PRJNA207719: Tissue specific transcriptome profiling

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Results for dmbx1a+dmbx1b

Z-value: 0.33

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Transcription factors associated with dmbx1a+dmbx1b

Gene Symbol	Gene ID	Gene Info
dmbx1b NCBI UniProt	ENSDARG00000002510	diencephalon/mesencephalon homeobox 1b
dmbx1a NCBI UniProt	ENSDARG00000009922	diencephalon/mesencephalon homeobox 1a

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
dmbx1b	dr11_v1_chr6_-_3573716_3573716	0.65	2.4e-01	Click!
dmbx1a	dr11_v1_chr2_-_10188598_10188598	0.63	2.6e-01	Click!

Activity profile of dmbx1a+dmbx1b motif

Sorted Z-values of dmbx1a+dmbx1b motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr11_+_1805421 Show fit	0.28	ENSDART00000173143	lrp1aa NCBI UniProt Show fit	low density lipoprotein receptor-related protein 1Aa
chr21_-_28340977 Show fit	0.19	ENSDART00000141629	nrxn2a NCBI UniProt Show fit	neurexin 2a
chr4_-_16628801 Show fit	0.17	ENSDART00000040708 ENSDART00000064009	caprin2 NCBI UniProt Show fit	caprin family member 2
chr15_+_36156986 Show fit	0.17	ENSDART00000059791	sst1.1 NCBI UniProt Show fit	somatostatin 1, tandem duplicate 1
chr13_-_14269626 Show fit	0.17	ENSDART00000079176	gfra4a NCBI UniProt Show fit	GDNF family receptor alpha 4a
chr2_+_243778 Show fit	0.16	ENSDART00000182262	CABZ01085887.1 NCBI UniProt Show fit
chr17_-_20979077 Show fit	0.15	ENSDART00000006676	phyhipla NCBI UniProt Show fit	phytanoyl-CoA 2-hydroxylase interacting protein-like a
chr10_+_24504292 Show fit	0.14	ENSDART00000090059	mtus2a NCBI UniProt Show fit	microtubule associated tumor suppressor candidate 2a
chr10_+_24504464 Show fit	0.13	ENSDART00000141387	mtus2a NCBI UniProt Show fit	microtubule associated tumor suppressor candidate 2a
chr1_-_45920632 Show fit	0.13	ENSDART00000140890	pnpla6 NCBI UniProt Show fit	patatin-like phospholipase domain containing 6

Showing 1 to 10 of 110 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of dmbx1a+dmbx1b

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:2000055	positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000055)
0.0	0.1	GO:0010874	regulation of cholesterol efflux(GO:0010874)
0.0	0.1	GO:1904059	regulation of locomotor rhythm(GO:1904059)
0.0	0.1	GO:1902590	virion assembly(GO:0019068) virus maturation(GO:0019075) multi-organism membrane organization(GO:0044803) viral budding(GO:0046755) multi-organism organelle organization(GO:1902590) multi-organism membrane budding(GO:1902592)
0.0	0.1	GO:0046470	phosphatidylcholine metabolic process(GO:0046470)
0.0	0.1	GO:0001579	medium-chain fatty acid transport(GO:0001579)
0.0	0.0	GO:0001954	positive regulation of cell-matrix adhesion(GO:0001954)
0.0	0.0	GO:1902767	farnesyl diphosphate biosynthetic process, mevalonate pathway(GO:0010142) isoprenoid biosynthetic process via mevalonate(GO:1902767)
0.0	0.0	GO:1903069	regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069)

Showing 1 to 9 of 9 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.1	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0	0.1	GO:1904121	phosphatidylethanolamine transporter activity(GO:1904121)
0.0	0.1	GO:0047777	(3S)-citramalyl-CoA lyase activity(GO:0047777)
0.0	0.1	GO:0098809	nitrite reductase activity(GO:0098809)
0.0	0.1	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.0	0.1	GO:1990050	phosphatidic acid transporter activity(GO:1990050)
0.0	0.1	GO:0072320	volume-sensitive chloride channel activity(GO:0072320)
0.0	0.0	GO:0004421	hydroxymethylglutaryl-CoA synthase activity(GO:0004421)

Showing 1 to 8 of 8 entries