PRJNA207719: Tissue specific transcriptome profiling


Results for ddx28+nfatc1+nfatc2b+nfatc3a+nfatc3b+nfatc4

Z-value: 1.76

Motif logo

Transcription factors associated with ddx28+nfatc1+nfatc2b+nfatc3a+nfatc3b+nfatc4

Gene Symbol Gene ID Gene Info
ENSDARG00000036168 nuclear factor of activated T cells 1
ENSDARG00000051729 nuclear factor of activated T cells 3b
ENSDARG00000054162 nuclear factor of activated T cells 4
ENSDARG00000076297 nuclear factor of activated T cells 3a
ENSDARG00000079972 nuclear factor of activated T cells 2b
ENSDARG00000112133 nuclear factor of activated T cells 3a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot

Activity profile of ddx28+nfatc1+nfatc2b+nfatc3a+nfatc3b+nfatc4 motif

Sorted Z-values of ddx28+nfatc1+nfatc2b+nfatc3a+nfatc3b+nfatc4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_26064480 1.46 ENSDART00000158215
LIM domain binding 3b
chr13_+_23157053 1.45 ENSDART00000162359
sorbin and SH3 domain containing 1
chr15_-_20933574 1.17 ENSDART00000152648
ubiquitin specific peptidase 2a
chr18_+_26743749 1.13 ENSDART00000145212
alpha-kinase 3a
chr1_-_38816685 1.09 ENSDART00000075230
ankyrin repeat and SOCS box containing 5b
chr2_-_24289641 0.97 ENSDART00000128784
myosin heavy chain 7-like
chr6_-_10233538 0.95 ENSDART00000182004
xin actin binding repeat containing 2a
chr22_-_15587360 0.89 ENSDART00000142717
tropomyosin 4a
chr14_+_49296052 0.86 ENSDART00000006073
annexin A6
chr3_-_39152478 0.85 ENSDART00000154550
chr9_+_6587056 0.83 ENSDART00000193421
four and a half LIM domains 2a
chr9_+_6587364 0.82 ENSDART00000122279
four and a half LIM domains 2a
chr8_-_40464935 0.80 ENSDART00000040013
myosin, light chain 7, regulatory
chr11_-_29946640 0.80 ENSDART00000079175
chr9_-_42989297 0.80 ENSDART00000126871
titin, tandem duplicate 2
chr1_-_41192059 0.79 ENSDART00000084665
docking protein 7
chr1_-_38195012 0.79 ENSDART00000020409
heart and neural crest derivatives expressed 2
chr25_-_28674739 0.78 ENSDART00000067073
leucine rich repeat containing 10
chr19_+_5674907 0.74 ENSDART00000042189
pyruvate dehydrogenase kinase, isozyme 2b
chr3_+_14463941 0.72 ENSDART00000170927
calponin 1, basic, smooth muscle, b
chr13_+_35690023 0.72 ENSDART00000128865
proteasome activator subunit 4a
chr2_+_42191592 0.72 ENSDART00000144716
caveolae associated protein 4a
chr12_+_17106117 0.70 ENSDART00000149990
actin, alpha 2, smooth muscle, aorta
chr7_+_65564163 0.68 ENSDART00000082679
microtubule associated monooxygenase, calponin and LIM domain containing 2a
chr11_-_30611814 0.66 ENSDART00000089803
solute carrier family 8 (sodium/calcium exchanger), member 1a
chr2_-_24369087 0.65 ENSDART00000081237
plasmalemma vesicle associated protein a
chr11_-_30612166 0.64 ENSDART00000177984
solute carrier family 8 (sodium/calcium exchanger), member 1a
chr25_+_6122823 0.62 ENSDART00000191824
RNA binding protein with multiple splicing 2a
chr16_+_25245857 0.60 ENSDART00000155220
kelch-like family member 38b
chr3_-_32817274 0.57 ENSDART00000142582
myosin light chain, phosphorylatable, fast skeletal muscle a
chr12_+_16281312 0.56 ENSDART00000152500
protein phosphatase 1, regulatory subunit 3Cb
chr13_-_22646134 0.56 ENSDART00000136808
multimerin 2a
chr4_+_2620751 0.55 ENSDART00000013924
G protein-coupled receptor 22a
chr2_+_4207209 0.54 ENSDART00000157903
GATA binding protein 6
chr20_+_1996202 0.54 ENSDART00000184143

chr7_-_21905851 0.53 ENSDART00000111066
erythropoietin a
chr14_-_33454595 0.52 ENSDART00000109615
transmembrane protein 255A
chr7_-_52558495 0.51 ENSDART00000138263
transcription factor 12
chr7_-_52531252 0.51 ENSDART00000174369
transcription factor 12
chr23_+_13814978 0.51 ENSDART00000090864
leiomodin 3 (fetal)
chr18_+_26750516 0.50 ENSDART00000110843
alpha-kinase 3a
chr13_-_13754091 0.50 ENSDART00000131255
kyphoscoliosis peptidase
chr11_-_30601401 0.50 ENSDART00000172244
solute carrier family 8 (sodium/calcium exchanger), member 1a
chr5_+_30179010 0.50 ENSDART00000134624
ADAM metallopeptidase with thrombospondin type 1 motif, 15a
chr16_-_12723324 0.50 ENSDART00000131915
SH3 domain binding kinase family, member 3
chr21_+_29077509 0.48 ENSDART00000128561
endothelial cell surface expressed chemotaxis and apoptosis regulator
chr20_+_53577502 0.48 ENSDART00000126983
myosin, heavy chain 6, cardiac muscle, alpha
chr3_-_61181018 0.47 ENSDART00000187970
parvalbumin 4
chr19_-_41069573 0.47 ENSDART00000111982
sarcoglycan, epsilon
chr16_+_30438041 0.47 ENSDART00000137977
platelet endothelial aggregation receptor 1
chr18_+_26719787 0.46 ENSDART00000141672
alpha-kinase 3a
chr6_-_50204262 0.45 ENSDART00000163648
RALY heterogeneous nuclear ribonucleoprotein
chr6_-_36552844 0.45 ENSDART00000023613
hairy-related 6
chr24_+_35975398 0.45 ENSDART00000173058
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF b
chr7_-_30367650 0.44 ENSDART00000075519
aldehyde dehydrogenase 1 family, member A2
chr25_+_14087045 0.44 ENSDART00000155770
actin, alpha, cardiac muscle 1c
chr25_-_32888115 0.43 ENSDART00000087586
C2 calcium dependent domain containing 4A
chr8_+_27743550 0.42 ENSDART00000046004
wingless-type MMTV integration site family, member 2Bb
chr21_+_21621042 0.42 ENSDART00000134907
transforming growth factor, beta 1b
chr18_+_5273953 0.42 ENSDART00000165073
solute carrier family 12 (sodium/potassium/chloride transporter), member 1
chr7_-_52417777 0.41 ENSDART00000110265
myocardial zonula adherens protein
chr20_+_31287356 0.40 ENSDART00000007688
solute carrier family 22 (organic cation/carnitine transporter), member 16
chr9_+_31752628 0.39 ENSDART00000060054
integrin, beta-like 1
chr6_-_48094342 0.39 ENSDART00000137458
solute carrier family 2 (facilitated glucose transporter), member 1b
chr8_-_19342111 0.39 ENSDART00000138881
ral guanine nucleotide dissociation stimulator-like 1
chr10_+_33990572 0.38 ENSDART00000138547
furry homolog b (Drosophila)
chr7_+_44445595 0.38 ENSDART00000108766
cadherin 5
chr9_+_33145522 0.37 ENSDART00000005879
ATP synthase peripheral stalk subunit OSCP
chr20_+_23173710 0.37 ENSDART00000074172
sarcoglycan, beta (dystrophin-associated glycoprotein)
chr22_+_28446557 0.36 ENSDART00000089546
ABI family, member 3 (NESH) binding protein b
chr10_-_7892192 0.36 ENSDART00000145480
smoothelin a
chr9_-_34944604 0.36 ENSDART00000140563
DCN1, defective in cullin neddylation 1, domain containing 2a
chr11_-_34628789 0.35 ENSDART00000192433
mitogen-activated protein kinase-activated protein kinase 3
chr10_-_42685512 0.35 ENSDART00000081347
stanniocalcin 1, like
chr6_+_48978202 0.35 ENSDART00000150023
solute carrier family 16 (monocarboxylate transporter), member 1a
chr22_+_28446365 0.35 ENSDART00000189359
ABI family, member 3 (NESH) binding protein b
chr21_-_22928214 0.35 ENSDART00000182760
chr7_+_27059330 0.34 ENSDART00000173919
pleckstrin homology domain containing, family A member 7b
chr6_-_33875919 0.33 ENSDART00000190411
transmembrane protein 69
chr8_+_17078692 0.31 ENSDART00000023206
polo-like kinase 2b (Drosophila)
chr11_-_11471857 0.30 ENSDART00000030103
keratin 94
chr19_+_43392446 0.30 ENSDART00000147290
Yes-related kinase
chr13_-_39947335 0.30 ENSDART00000056996
secreted frizzled-related protein 5
chr3_-_20091964 0.29 ENSDART00000029386
solute carrier family 4 (anion exchanger), member 1a (Diego blood group)
chr25_-_12902242 0.29 ENSDART00000164733
septin 15
chr8_-_45834825 0.29 ENSDART00000132965
oxoglutarate (alpha-ketoglutarate) dehydrogenase a (lipoamide)
chr2_+_38161318 0.28 ENSDART00000044264
matrix metallopeptidase 14b (membrane-inserted)
chr15_-_1066269 0.28 ENSDART00000093133
arylacetamide deacetylase
chr12_-_15205087 0.28 ENSDART00000010068
sulfotransferase family 1, cytosolic sulfotransferase 6
chr21_-_17603182 0.28 ENSDART00000020048
gelsolin a
chr9_+_4429593 0.28 ENSDART00000184855

chr9_-_23990416 0.27 ENSDART00000113176
collagen, type VI, alpha 3
chr13_-_18835254 0.27 ENSDART00000147579
leucine zipper, putative tumor suppressor 2a
chr14_-_3268155 0.27 ENSDART00000177244
platelet-derived growth factor receptor, beta polypeptide
chr16_-_35975254 0.27 ENSDART00000167537
eva-1 homolog Ba (C. elegans)
chr20_+_17783404 0.27 ENSDART00000181946
cadherin 2, type 1, N-cadherin (neuronal)
chr2_-_25140022 0.26 ENSDART00000134543
neutral cholesterol ester hydrolase 1a
chr4_-_9722568 0.26 ENSDART00000067190
tetraspanin 9b
chr23_-_19682971 0.26 ENSDART00000048891
chr13_+_1575276 0.26 ENSDART00000165987
chr13_+_49175624 0.26 ENSDART00000193550
egl-9 family hypoxia-inducible factor 1a
chr22_-_3564563 0.26 ENSDART00000145114
protein tyrosine phosphatase, receptor type, s, a
chr25_-_14087377 0.25 ENSDART00000124140
chr23_+_27703749 0.25 ENSDART00000027224
limb development membrane protein 1-like
chr10_+_8437930 0.25 ENSDART00000074553
PTC7 protein phosphatase homolog b
chr4_-_10826575 0.25 ENSDART00000164771
PTPRF interacting protein, binding protein 1a (liprin beta 1)
chr11_+_13630107 0.25 ENSDART00000172220
chr4_+_7677318 0.25 ENSDART00000149218
ELK3, ETS-domain protein
chr10_-_28761454 0.23 ENSDART00000129400
activated leukocyte cell adhesion molecule a
chr10_-_24689280 0.23 ENSDART00000191476
chr13_-_42749916 0.23 ENSDART00000140019
calpain 2, (m/II) large subunit a
chr4_-_49607096 0.23 ENSDART00000154381
chr16_-_13613475 0.23 ENSDART00000139102
D site albumin promoter binding protein b
chr17_+_12865746 0.23 ENSDART00000157083
Ral GTPase activating protein, alpha subunit 1 (catalytic)
chr12_+_27243059 0.23 ENSDART00000066269
ADP-ribosylation factor-like 4D
chr11_+_10541258 0.23 ENSDART00000132365
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5a
chr15_-_25099233 0.23 ENSDART00000192617
refilin B
chr15_-_34468599 0.22 ENSDART00000192984
mesenchyme homeobox 2a
chr19_-_33087246 0.22 ENSDART00000052078
kelch-like family member 38a
chr5_-_42950963 0.22 ENSDART00000149868
G-rich RNA sequence binding factor 1
chr21_-_43131752 0.22 ENSDART00000024137
procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide 2
chr6_+_27992886 0.22 ENSDART00000160354
angiomotin like 2a
chr16_+_46430627 0.22 ENSDART00000127681
rapunzel 6
chr6_+_49095646 0.22 ENSDART00000103385
solute carrier family 25, member 55a
chr14_+_26759332 0.22 ENSDART00000088484
AHNAK nucleoprotein
chr3_+_39099716 0.21 ENSDART00000083388
transmembrane protein 98
chr18_+_17786548 0.21 ENSDART00000189493
chr19_+_26340736 0.21 ENSDART00000013497
myosin regulatory light chain interacting protein a
chr5_-_48307804 0.21 ENSDART00000182831
myocyte enhancer factor 2cb
chr15_-_25099679 0.21 ENSDART00000154628
refilin B
chr16_+_23398369 0.21 ENSDART00000037694
S100 calcium binding protein A10b
chr11_-_40165683 0.21 ENSDART00000186510
chr23_+_27740788 0.21 ENSDART00000053871
desert hedgehog
chr14_-_448182 0.20 ENSDART00000180018
FAT atypical cadherin 4
chr2_-_3611960 0.20 ENSDART00000184579
phosphotriesterase related
chr9_-_35069645 0.20 ENSDART00000122679
amyloid beta (A4) precursor protein b
chr15_-_25518084 0.20 ENSDART00000158594
hypoxia-inducible factor 1, alpha subunit, like
chr16_+_31542645 0.19 ENSDART00000163724
Src like adaptor
chr10_+_8767541 0.19 ENSDART00000170272
integrin, alpha 1
chr5_-_68074592 0.19 ENSDART00000165052
sperm associated antigen 7
chr23_+_36101185 0.19 ENSDART00000103139
homeobox C8a
chr5_+_6617401 0.19 ENSDART00000060532
chr6_-_49673476 0.19 ENSDART00000112226
adenomatosis polyposis coli down-regulated 1-like
chr13_+_49175947 0.19 ENSDART00000056927
egl-9 family hypoxia-inducible factor 1a
chr21_+_2091895 0.19 ENSDART00000161828
chr19_-_38611814 0.19 ENSDART00000151958
collagen, type XVI, alpha 1
chr6_+_60112200 0.19 ENSDART00000008243
PRELI domain containing 3
chr25_-_12635371 0.19 ENSDART00000162463
zinc finger, CCHC domain containing 14
chr8_-_38403018 0.18 ENSDART00000134100
sorbin and SH3 domain containing 3
chr16_+_35887868 0.18 ENSDART00000169677
thyroid hormone receptor associated protein 3a
chr25_+_35683956 0.18 ENSDART00000149768
kinesin family member 21A
chr20_+_32118559 0.18 ENSDART00000026273
CD164 molecule, sialomucin
chr6_+_52263236 0.18 ENSDART00000144174
extended synaptotagmin-like protein 1b
chr25_-_35524166 0.18 ENSDART00000156782
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
chr13_+_16279890 0.18 ENSDART00000101775
annexin A11a
chr15_-_26923993 0.18 ENSDART00000132459
coiled-coil domain containing 9
chr23_+_23119008 0.17 ENSDART00000132418
sterile alpha motif domain containing 11
chr5_-_23277939 0.17 ENSDART00000003514
proteolipid protein 1b
chr13_-_31470439 0.17 ENSDART00000076574
reticulon 1a
chr20_-_47051996 0.17 ENSDART00000153330
DNA (cytosine-5-)-methyltransferase 3 alpha a
chr9_-_10805231 0.17 ENSDART00000193913
chr4_+_76926059 0.17 ENSDART00000136192
chr13_-_12581388 0.17 ENSDART00000079655
glutamyl aminopeptidase
chr9_-_12424791 0.17 ENSDART00000135447
chr7_+_52761841 0.17 ENSDART00000111444
diphosphoinositol pentakisphosphate kinase 1a
chr8_-_19904124 0.16 ENSDART00000129193
TraB domain containing 2B
chr5_-_24270989 0.16 ENSDART00000146251
chr9_+_27876146 0.16 ENSDART00000133997
armadillo repeat containing 8
chr16_+_23397785 0.16 ENSDART00000148961
S100 calcium binding protein A10b
chr12_+_46960579 0.16 ENSDART00000149032
ornithine aminotransferase
chr19_+_19652439 0.16 ENSDART00000165934
3-hydroxyisobutyrate dehydrogenase a
chr1_-_40102836 0.16 ENSDART00000147317
ciliary neurotrophic factor
chr9_+_43799829 0.16 ENSDART00000186240
ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
chr11_-_24532988 0.16 ENSDART00000067078
pleckstrin homology domain containing, family G (with RhoGef domain) member 5a
chr18_+_17786710 0.16 ENSDART00000190203
chr10_-_43771447 0.16 ENSDART00000052307
arrestin domain containing 3b
chr7_-_38658411 0.16 ENSDART00000109463
chr25_-_16818978 0.16 ENSDART00000104140
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
chr16_+_40301056 0.15 ENSDART00000058578
R-spondin 3
chr1_-_58664854 0.15 ENSDART00000109528
adhesion G protein-coupled receptor E5b, duplicate 3
chr12_+_20627505 0.15 ENSDART00000074384
syntaxin 4
chr8_+_2656681 0.15 ENSDART00000185067
family with sequence similarity 102, member Aa
chr9_-_23994225 0.15 ENSDART00000140346
collagen, type VI, alpha 3
chr13_+_13681681 0.15 ENSDART00000057825
complement factor D (adipsin)
chr8_-_49728590 0.15 ENSDART00000135714
G kinase anchoring protein 1
chr2_+_10914023 0.15 ENSDART00000146546
mitochondrial ribosomal protein L37
chr20_+_6773790 0.15 ENSDART00000169966
insulin-like growth factor binding protein 3
chr20_-_31496679 0.14 ENSDART00000153437
SAM and SH3 domain containing 1a
chr5_-_44496553 0.14 ENSDART00000178081
growth arrest-specific 1a
chr15_-_21852963 0.14 ENSDART00000153581
layilin b
chr13_-_377256 0.14 ENSDART00000137398
chr9_-_16133263 0.14 ENSDART00000077187
myosin IB
chr17_-_42799104 0.13 ENSDART00000154755
protein kinase D3
chr17_+_30448452 0.13 ENSDART00000153939
lipin 1
chr1_+_36772348 0.13 ENSDART00000109314
Rho GTPase activating protein 10
chr13_+_43639867 0.13 ENSDART00000042588
zinc finger, FYVE domain containing 21
chr18_+_39416357 0.13 ENSDART00000183174
LysM, putative peptidoglycan-binding, domain containing 2
chr9_-_8454060 0.13 ENSDART00000110158
insulin receptor substrate 2b
chr9_+_25832329 0.13 ENSDART00000130059
zinc finger E-box binding homeobox 2a
chr24_-_21819010 0.13 ENSDART00000091096

Network of associatons between targets according to the STRING database.

First level regulatory network of ddx28+nfatc1+nfatc2b+nfatc3a+nfatc3b+nfatc4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0090131 mesenchyme migration(GO:0090131)
0.2 0.9 GO:0003413 plasma membrane repair(GO:0001778) chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413) growth plate cartilage chondrocyte differentiation(GO:0003418)
0.2 1.3 GO:0055014 atrial cardiac muscle cell development(GO:0055014)
0.1 0.3 GO:0061031 endodermal digestive tract morphogenesis(GO:0061031)
0.1 0.4 GO:1900158 negative regulation of chondrocyte differentiation(GO:0032331) negative regulation of cartilage development(GO:0061037) negative regulation of chondrocyte development(GO:0061182) regulation of bone mineralization involved in bone maturation(GO:1900157) negative regulation of bone mineralization involved in bone maturation(GO:1900158) negative regulation of bone development(GO:1903011)
0.1 0.4 GO:0015695 organic cation transport(GO:0015695)
0.1 0.8 GO:0071908 determination of intestine left/right asymmetry(GO:0071908)
0.1 0.6 GO:0051148 negative regulation of muscle cell differentiation(GO:0051148)
0.1 0.7 GO:0007289 spermatid nucleus differentiation(GO:0007289) sperm chromatin condensation(GO:0035092) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 0.3 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341)
0.1 0.7 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 0.4 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 0.5 GO:0043011 myeloid dendritic cell activation(GO:0001773) myeloid dendritic cell differentiation(GO:0043011)
0.1 0.4 GO:0061010 gall bladder development(GO:0061010)
0.1 0.4 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 0.3 GO:0021577 hindbrain structural organization(GO:0021577) dorsal fin morphogenesis(GO:0035142) cell motility involved in somitogenic axis elongation(GO:0090247) cell migration involved in somitogenic axis elongation(GO:0090248)
0.1 1.8 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 0.5 GO:0048823 nucleate erythrocyte development(GO:0048823)
0.1 0.3 GO:0014909 smooth muscle cell migration(GO:0014909)
0.1 0.4 GO:0001955 blood vessel maturation(GO:0001955) regulation of establishment of cell polarity(GO:2000114)
0.1 0.5 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.8 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.1 0.3 GO:0030908 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.1 1.2 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.8 GO:0048769 sarcomerogenesis(GO:0048769)
0.0 0.4 GO:0021794 thalamus development(GO:0021794)
0.0 0.5 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.0 0.1 GO:1904407 regulation of nitric oxide biosynthetic process(GO:0045428) positive regulation of nitric oxide biosynthetic process(GO:0045429) positive regulation of reactive oxygen species biosynthetic process(GO:1903428) positive regulation of nitric oxide metabolic process(GO:1904407)
0.0 0.1 GO:0010712 regulation of collagen metabolic process(GO:0010712) regulation of collagen biosynthetic process(GO:0032965) regulation of multicellular organismal metabolic process(GO:0044246)
0.0 0.2 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.0 0.1 GO:0098529 neuromuscular junction development, skeletal muscle fiber(GO:0098529)
0.0 0.1 GO:0061355 Wnt protein secretion(GO:0061355)
0.0 0.3 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.7 GO:0019471 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.0 0.1 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.0 0.3 GO:0051013 microtubule severing(GO:0051013)
0.0 0.2 GO:0035912 establishment of cell polarity involved in ameboidal cell migration(GO:0003365) aorta morphogenesis(GO:0035909) dorsal aorta morphogenesis(GO:0035912)
0.0 2.0 GO:0010842 retina layer formation(GO:0010842)
0.0 1.3 GO:0010906 regulation of glucose metabolic process(GO:0010906)
0.0 0.6 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
0.0 0.3 GO:0099560 synaptic membrane adhesion(GO:0099560)
0.0 0.2 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.1 GO:0007412 axon target recognition(GO:0007412)
0.0 0.4 GO:0045116 protein neddylation(GO:0045116)
0.0 1.2 GO:0030834 regulation of actin filament depolymerization(GO:0030834) negative regulation of actin filament depolymerization(GO:0030835)
0.0 0.2 GO:0015810 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.0 0.5 GO:1990798 pancreas regeneration(GO:1990798)
0.0 0.1 GO:0019408 dolichol biosynthetic process(GO:0019408)
0.0 0.1 GO:0060406 copulation(GO:0007620) regulation of epinephrine secretion(GO:0014060) positive regulation of epinephrine secretion(GO:0032812) positive regulation of catecholamine secretion(GO:0033605) penile erection(GO:0043084) epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242) regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406) prolactin secretion(GO:0070459)
0.0 0.0 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827)
0.0 0.2 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.0 0.0 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.0 0.1 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.0 0.1 GO:1903646 regulation of protein folding(GO:1903332) positive regulation of protein folding(GO:1903334) regulation of chaperone-mediated protein folding(GO:1903644) positive regulation of chaperone-mediated protein folding(GO:1903646)
0.0 0.2 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.0 0.2 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.4 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.3 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.1 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.1 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.0 0.2 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.1 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.2 GO:0071456 response to activity(GO:0014823) cellular response to hypoxia(GO:0071456)
0.0 0.1 GO:0051601 exocyst localization(GO:0051601)
0.0 0.2 GO:0007622 rhythmic behavior(GO:0007622) circadian behavior(GO:0048512)
0.0 0.1 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.3 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.3 GO:0051923 sulfation(GO:0051923)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.2 GO:0043034 costamere(GO:0043034)
0.1 0.5 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.4 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 1.0 GO:0031430 M band(GO:0031430)
0.0 0.7 GO:0005869 dynactin complex(GO:0005869)
0.0 1.8 GO:0031941 filamentous actin(GO:0031941)
0.0 0.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.2 GO:0034657 GID complex(GO:0034657)
0.0 0.3 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 2.2 GO:0042383 sarcolemma(GO:0042383)
0.0 0.3 GO:0014704 intercalated disc(GO:0014704)
0.0 1.7 GO:0030018 Z disc(GO:0030018)
0.0 1.6 GO:0030017 sarcomere(GO:0030017)
0.0 0.1 GO:0072380 TRC complex(GO:0072380)
0.0 0.6 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 1.8 GO:0016459 myosin complex(GO:0016459)
0.0 0.6 GO:0008305 integrin complex(GO:0008305)
0.0 0.4 GO:0032432 actin filament bundle(GO:0032432)
0.0 0.2 GO:0043209 myelin sheath(GO:0043209)
0.0 0.6 GO:0030496 midbody(GO:0030496)
0.0 0.8 GO:0005814 centriole(GO:0005814)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.1 1.8 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.7 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.1 0.4 GO:0031005 filamin binding(GO:0031005)
0.1 0.7 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.2 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.1 1.5 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1 0.7 GO:0016504 peptidase activator activity(GO:0016504)
0.1 0.4 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.3 GO:0048407 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor binding(GO:0048407)
0.1 0.4 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.4 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.2 GO:0033857 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.2 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity(GO:0008442)
0.0 0.6 GO:2001069 glycogen binding(GO:2001069)
0.0 0.3 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.3 GO:0005113 patched binding(GO:0005113)
0.0 0.7 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.1 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.4 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.8 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.2 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.5 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.5 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.8 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.1 GO:0046592 polyamine oxidase activity(GO:0046592)
0.0 0.9 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.2 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0005153 interleukin-8 receptor binding(GO:0005153)
0.0 0.3 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 0.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.2 GO:0030546 receptor activator activity(GO:0030546) receptor agonist activity(GO:0048018)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.1 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.2 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.0 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.0 0.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.2 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.6 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.3 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.2 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.5 PID HES HEY PATHWAY Notch-mediated HES/HEY network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 0.4 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.4 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 1.2 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 0.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.1 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE