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PRJNA207719: Tissue specific transcriptome profiling

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Results for cux2b

Z-value: 1.40

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Transcription factors associated with cux2b

Gene Symbol Gene ID Gene Info
ENSDARG00000086345 cut-like homeobox 2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
cux2bdr11_v1_chr8_-_4327473_4327473-0.913.1e-02Click!

Activity profile of cux2b motif

Sorted Z-values of cux2b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_21376290 1.74 ENSDART00000136765
elastase 2
chr8_-_21372446 1.29 ENSDART00000061481
ENSDART00000079293
elastase 2 like
chr10_+_2715548 1.13 ENSDART00000130793
G protein-coupled receptor kinase 5
chr1_-_52447364 1.11 ENSDART00000140740
si:ch211-217k17.10
chr21_+_5531138 1.05 ENSDART00000163825
lymphocyte antigen 6 family member M6
chr23_-_10175898 1.02 ENSDART00000146185
keratin 5
chr17_-_51651631 0.89 ENSDART00000154699
chemokine (C-C motif) receptor 6b
chr11_-_18253111 0.87 ENSDART00000125984
musculoskeletal, embryonic nuclear protein 1b
chr23_+_32039386 0.82 ENSDART00000133801
myosin light chain kinase 2
chr13_+_24402406 0.80 ENSDART00000043002
RAB1A, member RAS oncogene family b
chr11_+_10984293 0.77 ENSDART00000065933
integrin, beta 6
chr14_+_46020571 0.73 ENSDART00000157617
ENSDART00000083928
C1q and TNF related 2
chr20_+_53541389 0.69 ENSDART00000100110
p21 protein (Cdc42/Rac)-activated kinase 6b
chr20_+_38279523 0.66 ENSDART00000061311
chemokine (C-C motif) ligand 38, duplicate 5
chr17_+_45577326 0.65 ENSDART00000074854
si:ch211-202f3.3
chr11_+_20899029 0.63 ENSDART00000163029
zgc:162182
chr17_-_25382367 0.62 ENSDART00000162306
ENSDART00000165282
LCK proto-oncogene, Src family tyrosine kinase
chr17_-_8899323 0.62 ENSDART00000081590
NK-lysin tandem duplicate 1
chr11_-_45185792 0.62 ENSDART00000171328
si:dkey-93h22.7
chr19_-_40199081 0.61 ENSDART00000051970
ENSDART00000151079
granulin 2
chr14_-_34512859 0.61 ENSDART00000140368
si:ch211-232m8.3
chr2_+_45511459 0.60 ENSDART00000132101
AKNA domain containing 1
chr25_-_37319117 0.59 ENSDART00000044499
immunoglobulin light 4 variable 9
chr10_-_2943474 0.59 ENSDART00000188698
occludin a
chr14_-_899170 0.59 ENSDART00000165211
ENSDART00000031992
regulator of G protein signaling 14a
chr9_+_41224100 0.59 ENSDART00000141792
signal transducer and activator of transcription 1b
chr25_-_37322081 0.57 ENSDART00000128285
immunoglobulin light 4 variable 10
chr21_-_22689805 0.57 ENSDART00000157560
ENSDART00000110792
grass carp reovirus (GCRV)-induced gene 2e
chr24_-_31306724 0.57 ENSDART00000165399
acid phosphatase 5b, tartrate resistant
chr19_+_43119698 0.55 ENSDART00000167847
ENSDART00000186962
ENSDART00000187305
eukaryotic translation elongation factor 1 alpha 1, like 1
chr7_-_19168375 0.55 ENSDART00000112447
interleukin 13 receptor, alpha 1
chr16_+_50953842 0.55 ENSDART00000174709
si:dkeyp-97a10.1
chr14_-_970853 0.54 ENSDART00000130801
acyl-CoA synthetase long chain family member 1b
chr6_+_3373665 0.54 ENSDART00000134133
ST3 beta-galactoside alpha-2,3-sialyltransferase 3a
chr19_-_41518922 0.54 ENSDART00000164483
ENSDART00000062080
chromatin accessibility complex 1
chr20_-_25902141 0.54 ENSDART00000142611
ENSDART00000024821
ELM2 and Myb/SANT-like domain containing 1a
chr5_-_38820046 0.52 ENSDART00000182886
CCR4-NOT transcription complex, subunit 6-like
chr4_+_77933084 0.52 ENSDART00000148728
protein kinase C and casein kinase substrate in neurons 2
chr16_-_33001153 0.51 ENSDART00000147941
malic enzyme 1, NADP(+)-dependent, cytosolic
chr4_+_25558849 0.51 ENSDART00000113663
ENSDART00000100755
ENSDART00000111416
ENSDART00000127840
ENSDART00000168618
ENSDART00000111820
ENSDART00000113866
ENSDART00000110107
ENSDART00000111344
ENSDART00000108548
zgc:195175
chr13_+_50375800 0.51 ENSDART00000099537
cytochrome c oxidase subunit Vb 2
chr2_-_15324837 0.51 ENSDART00000015655
trans-2,3-enoyl-CoA reductase-like 2b
chr4_-_44500201 0.51 ENSDART00000150460
si:dkeyp-100h4.7
chr25_-_37314700 0.51 ENSDART00000017807
immunoglobulin light 4 variable 8
chr1_+_21563311 0.50 ENSDART00000147076
ENSDART00000006147
primase and polymerase (DNA-directed)
chr8_-_13574764 0.50 ENSDART00000076561
si:ch211-126g16.10
chr4_+_44454270 0.50 ENSDART00000150482
si:dkeyp-100h4.4
chr7_+_1579510 0.50 ENSDART00000190525
SPT16 homolog, facilitates chromatin remodeling subunit
chr2_-_45510699 0.50 ENSDART00000024034
ENSDART00000145634
G protein signaling modulator 2
chr23_-_45705525 0.49 ENSDART00000148959
endothelin receptor type Ab
chr18_+_31073265 0.49 ENSDART00000023539
cytochrome b-245, alpha polypeptide
chr14_+_46020282 0.49 ENSDART00000190087
C1q and TNF related 2
chr14_-_34059681 0.49 ENSDART00000003993
IL2 inducible T cell kinase
chr16_+_29509133 0.49 ENSDART00000112116
cathepsin S, ortholog2, tandem duplicate 1
chr3_-_29506960 0.48 ENSDART00000141720
cytohesin 4a
chr24_-_27452488 0.48 ENSDART00000136433
chemokine (C-C motif) ligand 34b, duplicate 8
chr11_-_29658396 0.47 ENSDART00000183947
ribosomal protein L22
chr24_-_36680261 0.47 ENSDART00000059507
chemokine (C-C motif) receptor 10
chr1_+_38153944 0.47 ENSDART00000135666
UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7
chr7_-_16598212 0.47 ENSDART00000128488
E2F transcription factor 8
chr10_-_45210184 0.46 ENSDART00000167128
poly (ADP-ribose) glycohydrolase, like
chr7_-_38658411 0.46 ENSDART00000109463
ENSDART00000017155
nephrosin
chr5_-_71705191 0.46 ENSDART00000187767
adenylate kinase 1
chr17_-_11439815 0.46 ENSDART00000130105
proteasome subunit alpha 3
chr11_+_36243774 0.46 ENSDART00000023323
zgc:172270
chr25_+_3648497 0.45 ENSDART00000160017

chr3_-_16784280 0.45 ENSDART00000137108
ENSDART00000137276
si:dkey-30j10.5
chr19_-_48330287 0.45 ENSDART00000162244
si:ch73-359m17.7
chr8_-_45760087 0.45 ENSDART00000025620
peptidylprolyl isomerase Aa (cyclophilin A)
chr11_-_29657947 0.45 ENSDART00000125753
ribosomal protein L22
chr4_+_25574827 0.45 ENSDART00000187726
zgc:195175
chr16_+_35870456 0.45 ENSDART00000184321
thyroid hormone receptor associated protein 3a
chr25_+_29160102 0.45 ENSDART00000162854
pyruvate kinase M1/2b
chr19_-_48391415 0.45 ENSDART00000170726
ENSDART00000169577
si:ch73-359m17.2
chr21_+_5560040 0.44 ENSDART00000163205
si:ch211-134a4.6
chr2_+_2737422 0.44 ENSDART00000032459
aquaporin 1a (Colton blood group), tandem duplicate 1
chr23_-_43424510 0.44 ENSDART00000055564
regulation of nuclear pre-mRNA domain containing 1B
chr12_+_20641471 0.43 ENSDART00000133654
calcium binding and coiled-coil domain 2
chr23_+_16908012 0.43 ENSDART00000133946
si:dkey-147f3.8
chr23_-_5818992 0.43 ENSDART00000148730
cysteine and glycine-rich protein 1a
chr2_+_51028269 0.43 ENSDART00000161254
eukaryotic translation elongation factor 1 delta a (guanine nucleotide exchange protein)
chr19_-_48336535 0.43 ENSDART00000162752
si:ch73-359m17.6
chr17_+_35362851 0.43 ENSDART00000137659
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr21_-_26490186 0.42 ENSDART00000009889
zgc:110540
chr3_-_15451097 0.42 ENSDART00000163836
Danio rerio linker for activation of T cells (lat), mRNA.
chr1_+_57041549 0.41 ENSDART00000152198
si:ch211-1f22.16
chr22_-_10580194 0.41 ENSDART00000105848
si:dkey-42i9.7
chr25_+_753364 0.41 ENSDART00000183804
twinfilin actin binding protein 1
chr3_-_60316118 0.40 ENSDART00000171458
si:ch211-214b16.2
chr10_+_15088534 0.40 ENSDART00000142865
si:ch211-95j8.3
chr1_-_58115298 0.40 ENSDART00000141787
caspase b, like
chr13_+_46941930 0.40 ENSDART00000056962
F-box protein 5
chr15_-_21239416 0.40 ENSDART00000155787
si:dkey-105h12.2
chr24_-_39826865 0.40 ENSDART00000089232
solute carrier family 12 (potassium/chloride transporter), member 7b
chr5_+_11840905 0.40 ENSDART00000030444
tescalcin a
chr25_-_13319112 0.40 ENSDART00000179885
si:ch211-194m7.8
chr17_-_5424175 0.40 ENSDART00000171063
ENSDART00000188102
SPT3 homolog, SAGA and STAGA complex component
chr1_-_45049603 0.39 ENSDART00000023336
ribosomal protein S6
chr1_-_52498146 0.39 ENSDART00000122217
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr23_+_16807209 0.38 ENSDART00000141966
zgc:114081
chr7_+_30626378 0.38 ENSDART00000173533
ENSDART00000052541
cyclin B2
chr12_+_8822717 0.38 ENSDART00000021628
receptor accessory protein 3b
chr19_-_46018152 0.38 ENSDART00000159206
KRIT1, ankyrin repeat containing
chr7_-_54320088 0.37 ENSDART00000172396
Fas (tnfrsf6)-associated via death domain
chr1_+_55304374 0.37 ENSDART00000152352
si:ch211-286b5.8
chr2_-_36918709 0.37 ENSDART00000084876
zgc:153654
chr4_+_5842433 0.37 ENSDART00000124085
ENSDART00000179848
ubiquitin specific peptidase 18
chr12_-_4532066 0.37 ENSDART00000092687
transient receptor potential cation channel, subfamily M, member 4b, transient receptor potential cation channel, subfamily M, member 4b, tandem duplicate 2
chr9_+_10692905 0.37 ENSDART00000061499
chemokine (C-X-C motif), receptor 4b
chr17_-_2584423 0.37 ENSDART00000013506
zona pellucida glycoprotein 3, tandem duplicate 2
chr23_+_38171186 0.36 ENSDART00000148188
zgc:112994
chr11_+_11200550 0.36 ENSDART00000181339
ENSDART00000187116
myomesin 2a
chr5_+_6672870 0.36 ENSDART00000126598
paxillin a
chr7_-_28658143 0.36 ENSDART00000173556
adhesion G protein-coupled receptor G1
chr4_-_21652812 0.36 ENSDART00000174400
ribosomal protein S16
chr25_+_16194450 0.36 ENSDART00000141994
microtubule associated monooxygenase, calponin and LIM domain containing 2b
chr7_+_19817306 0.36 ENSDART00000044425

chr17_-_2578026 0.36 ENSDART00000065821
zona pellucida glycoprotein 3, tandem duplicate 2
chr11_+_42474694 0.36 ENSDART00000056048
ENSDART00000184710
si:ch1073-165f9.2
chr10_-_7785930 0.35 ENSDART00000043961
ENSDART00000111058
myeloid-specific peroxidase
chr1_-_8000428 0.35 ENSDART00000133098
si:dkey-79f11.5
chr24_+_30215475 0.35 ENSDART00000164717
si:ch73-358j7.2
chr18_+_20566817 0.35 ENSDART00000100716
BH3 interacting domain death agonist
chr8_+_554531 0.34 ENSDART00000193623

chr8_+_23726244 0.34 ENSDART00000132734
makorin, ring finger protein, 4
chr3_-_43872889 0.34 ENSDART00000170553
mesothelin a
chr23_-_21515182 0.34 ENSDART00000142000
ring finger protein 207b
chr6_+_36839509 0.34 ENSDART00000190605
ENSDART00000104160
zgc:110788
chr19_+_2631565 0.34 ENSDART00000171487
family with sequence similarity 126, member A
chr8_+_44783424 0.34 ENSDART00000025875
si:ch1073-459j12.1
chr4_-_1147655 0.33 ENSDART00000171561
si:ch211-117i20.2
chr22_-_6144428 0.33 ENSDART00000106118
si:dkey-19a16.4
chr17_+_53435279 0.33 ENSDART00000126630
connexin 52.9
chr11_+_37201483 0.33 ENSDART00000160930
ENSDART00000173439
ENSDART00000171273
zgc:112265
chr3_+_19621034 0.33 ENSDART00000025358
integrin beta 3a
chr4_-_12914163 0.33 ENSDART00000140002
ENSDART00000145917
ENSDART00000141355
ENSDART00000067135
methionine sulfoxide reductase B3
chr19_-_38539670 0.33 ENSDART00000136775
collagen, type XVI, alpha 1
chr22_-_15602760 0.33 ENSDART00000009054
tropomyosin 4a
chr25_+_32390794 0.32 ENSDART00000012600
galactokinase 2
chr18_+_2554666 0.32 ENSDART00000167218
purinergic receptor P2Y2, tandem duplicate 1
chr22_-_10158038 0.32 ENSDART00000047444
RanBP-type and C3HC4-type zinc finger containing 1
chr21_+_6114709 0.32 ENSDART00000065858
folylpolyglutamate synthase
chr25_+_37435335 0.32 ENSDART00000171602
charged multivesicular body protein 1A
chr24_+_2962988 0.32 ENSDART00000164449
enoyl-CoA delta isomerase 2
chr1_-_34713710 0.32 ENSDART00000141569
ENSDART00000102111
ENSDART00000122137
tumor protein, translationally-controlled 1
chr1_+_292545 0.32 ENSDART00000148261
centromere protein E
chr17_+_4398102 0.31 ENSDART00000152387
si:zfos-364h11.1
chr6_-_27891961 0.31 ENSDART00000155116
im:7152348
chr5_-_29587351 0.31 ENSDART00000136446
ENSDART00000051434
ectonucleoside triphosphate diphosphohydrolase 2a, tandem duplicate 1
chr9_+_52398531 0.31 ENSDART00000126215
death associated protein 1b
chr11_+_14280598 0.31 ENSDART00000163033
si:ch211-262i1.3
chr19_-_18130567 0.31 ENSDART00000190659
ENSDART00000022803
sorting nexin 10a
chr2_+_33326522 0.31 ENSDART00000056655
Kruppel-like factor 17
chr2_+_16160906 0.31 ENSDART00000135783
selenoprotein J
chr7_-_16596938 0.30 ENSDART00000134548
E2F transcription factor 8
chr25_+_37290206 0.30 ENSDART00000086474
si:dkey-234i14.12
chr7_+_20393386 0.30 ENSDART00000173471
si:dkey-33c9.6
chr7_+_4824882 0.30 ENSDART00000137369
si:dkey-28d5.7
chr25_+_37297659 0.30 ENSDART00000086733
si:dkey-234i14.13
chr2_-_51794472 0.30 ENSDART00000186652

chr9_+_3087889 0.30 ENSDART00000146148
protein phosphatase 1 regulatory subunit 9A-like A
chr13_-_22843562 0.30 ENSDART00000142738
phenazine biosynthesis like protein domain containing
chr6_+_2097690 0.30 ENSDART00000193770
transglutaminase 2b
chr11_-_27962757 0.29 ENSDART00000147386
endothelin converting enzyme 1
chr24_+_25913162 0.29 ENSDART00000143099
ENSDART00000184814
mitogen-activated protein kinase kinase kinase 15
chr8_+_22404981 0.29 ENSDART00000185211
ENSDART00000099972
si:dkey-23c22.7
si:dkey-23c22.9
chr10_+_10801719 0.29 ENSDART00000193648
alpha-1-microglobulin/bikunin precursor
chr4_-_42391176 0.29 ENSDART00000189739
si:ch211-59d8.2
chr20_+_38910214 0.29 ENSDART00000047362
methionine sulfoxide reductase A
chr12_+_695619 0.29 ENSDART00000161691
ATP-binding cassette, sub-family C (CFTR/MRP), member 3
chr2_+_36004381 0.29 ENSDART00000098706
laminin, gamma 2
chr23_-_43486714 0.28 ENSDART00000169726
E2F transcription factor 1
chr6_-_24143923 0.28 ENSDART00000157948
si:ch73-389b16.1
chr25_+_37435720 0.28 ENSDART00000164390
charged multivesicular body protein 1A
chr10_+_13209580 0.28 ENSDART00000000887
ENSDART00000136932
Ras association (RalGDS/AF-6) domain family 6
chr22_+_19425657 0.28 ENSDART00000187531
ENSDART00000078804
si:dkey-78l4.5
chr13_+_12671513 0.28 ENSDART00000010517
eukaryotic translation initiation factor 4eb
chr21_-_40174647 0.28 ENSDART00000183738
ENSDART00000076840
ENSDART00000145109
solute carrier organic anion transporter family, member 2B1
chr25_+_36349574 0.28 ENSDART00000184101
zgc:173552
chr8_-_46457233 0.28 ENSDART00000113214
sulfotransferase family 1, cytosolic sulfotransferase 7
chr13_+_1155536 0.28 ENSDART00000148356
PERP, TP53 apoptosis effector
chr21_+_45268112 0.28 ENSDART00000157136
transcription factor 7
chr20_-_54869006 0.28 ENSDART00000184817

chr22_-_6923086 0.27 ENSDART00000122634

chr9_-_31108285 0.27 ENSDART00000003193
G protein-coupled receptor 183a
chr3_-_40275096 0.27 ENSDART00000141578
serine hydroxymethyltransferase 1 (soluble)
chr3_-_32071468 0.27 ENSDART00000121979

chr23_+_32101202 0.27 ENSDART00000000992
zgc:56699
chr21_+_45267589 0.27 ENSDART00000182963
ENSDART00000155681
ENSDART00000192632
transcription factor 7
chr11_-_18254 0.27 ENSDART00000167814
proline rich 13
chr3_-_62403550 0.27 ENSDART00000055055
SRY (sex determining region Y)-box 8b
chr20_+_20499869 0.27 ENSDART00000036124
SIX homeobox 1b
chr7_+_2236317 0.27 ENSDART00000075859
zgc:172065
chr1_-_9195629 0.27 ENSDART00000143587
ENSDART00000192174
endoplasmic reticulum to nucleus signaling 2
chr13_+_37273221 0.27 ENSDART00000035011
glycoprotein hormone beta 5
chr1_+_19332837 0.26 ENSDART00000078594
tyrosinase-related protein 1b
chr13_-_27354003 0.26 ENSDART00000101479
ENSDART00000044652
DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
chr10_-_41352502 0.26 ENSDART00000052971
ENSDART00000128156
RAB11 family interacting protein 1 (class I) b
chr7_+_4922104 0.26 ENSDART00000135154
si:dkey-28d5.11
chr8_-_13013123 0.26 ENSDART00000147802
DENN/MADD domain containing 2Da

Network of associatons between targets according to the STRING database.

First level regulatory network of cux2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0033301 cell cycle comprising mitosis without cytokinesis(GO:0033301)
0.2 0.7 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.2 0.9 GO:0035988 chondrocyte proliferation(GO:0035988)
0.2 0.5 GO:0060631 regulation of meiosis I(GO:0060631)
0.2 0.5 GO:0002155 regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.2 0.6 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.1 0.4 GO:0003097 renal water homeostasis(GO:0003091) renal water transport(GO:0003097)
0.1 0.4 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.1 0.4 GO:0030857 negative regulation of epithelial cell differentiation(GO:0030857)
0.1 0.4 GO:0002369 T cell cytokine production(GO:0002369)
0.1 0.5 GO:0060307 regulation of membrane repolarization(GO:0060306) regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307) regulation of cardiac muscle cell membrane repolarization(GO:0099623) ventricular cardiac muscle cell membrane repolarization(GO:0099625)
0.1 0.3 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.1 0.4 GO:0002568 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.1 0.3 GO:0048785 hatching gland development(GO:0048785)
0.1 0.4 GO:0051444 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.1 1.0 GO:0044854 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.1 0.4 GO:0021730 trigeminal sensory nucleus development(GO:0021730)
0.1 0.3 GO:0036336 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.1 0.3 GO:0019264 L-serine catabolic process(GO:0006565) glycine biosynthetic process from serine(GO:0019264)
0.1 0.3 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.1 0.2 GO:0021698 cerebellar Purkinje cell layer structural organization(GO:0021693) cerebellar cortex structural organization(GO:0021698) CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.1 0.2 GO:0007414 axonal defasciculation(GO:0007414)
0.1 0.3 GO:0030091 protein repair(GO:0030091)
0.1 0.5 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 0.3 GO:0070257 regulation of mucus secretion(GO:0070255) positive regulation of mucus secretion(GO:0070257)
0.1 0.3 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.1 0.2 GO:0007571 age-dependent general metabolic decline(GO:0007571)
0.1 0.2 GO:0043385 mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376)
0.1 0.2 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 0.5 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.1 0.2 GO:0090069 regulation of ribosome biogenesis(GO:0090069)
0.1 0.5 GO:0003319 cardioblast migration to the midline involved in heart rudiment formation(GO:0003319)
0.1 2.3 GO:0002377 immunoglobulin production(GO:0002377)
0.1 0.5 GO:0009180 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.1 0.4 GO:0032608 interferon-beta production(GO:0032608) regulation of interferon-beta production(GO:0032648) positive regulation of interferon-beta production(GO:0032728)
0.1 0.3 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.1 0.3 GO:0070986 left/right axis specification(GO:0070986)
0.1 0.5 GO:0042554 superoxide anion generation(GO:0042554)
0.1 0.2 GO:0043455 regulation of secondary metabolic process(GO:0043455)
0.1 0.6 GO:0006108 malate metabolic process(GO:0006108)
0.1 0.2 GO:1904031 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.1 0.4 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 0.9 GO:0034724 DNA replication-independent nucleosome organization(GO:0034724)
0.1 0.6 GO:0071357 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.1 0.9 GO:0007339 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 0.3 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.1 0.3 GO:0097066 response to thyroid hormone(GO:0097066)
0.1 0.2 GO:0071635 transforming growth factor beta activation(GO:0036363) regulation of transforming growth factor beta production(GO:0071634) negative regulation of transforming growth factor beta production(GO:0071635)
0.1 0.2 GO:2000660 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.2 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.8 GO:0071594 T cell differentiation in thymus(GO:0033077) thymocyte aggregation(GO:0071594)
0.0 0.3 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.2 GO:0017003 protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063)
0.0 0.4 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.1 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.0 0.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.2 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.1 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.2 GO:0051414 response to cortisol(GO:0051414)
0.0 0.8 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.2 GO:0043420 anthranilate metabolic process(GO:0043420)
0.0 0.6 GO:0008354 germ cell migration(GO:0008354)
0.0 0.1 GO:0061032 visceral serous pericardium development(GO:0061032)
0.0 1.0 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.1 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.2 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.0 1.2 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.4 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.2 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.2 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.4 GO:2000377 regulation of reactive oxygen species metabolic process(GO:2000377)
0.0 0.4 GO:0061055 myotome development(GO:0061055)
0.0 0.8 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.0 0.1 GO:0055107 Golgi to secretory granule transport(GO:0055107)
0.0 0.2 GO:1901099 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.1 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.2 GO:0046341 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.1 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.2 GO:0021588 cerebellum formation(GO:0021588)
0.0 0.1 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.2 GO:0031274 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.3 GO:2000406 positive regulation of lymphocyte migration(GO:2000403) positive regulation of T cell migration(GO:2000406)
0.0 1.1 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.2 GO:0051673 membrane disruption in other organism(GO:0051673)
0.0 0.4 GO:0071174 mitotic spindle assembly checkpoint(GO:0007094) spindle checkpoint(GO:0031577) negative regulation of mitotic metaphase/anaphase transition(GO:0045841) spindle assembly checkpoint(GO:0071173) mitotic spindle checkpoint(GO:0071174)
0.0 0.1 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.6 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.1 GO:0060912 cardiac cell fate specification(GO:0060912)
0.0 0.1 GO:0006031 chitin biosynthetic process(GO:0006031) glucosamine-containing compound biosynthetic process(GO:1901073)
0.0 0.1 GO:0003314 heart rudiment morphogenesis(GO:0003314)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.1 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.0 0.3 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.3 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.3 GO:0045471 response to ethanol(GO:0045471)
0.0 0.4 GO:0006278 RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.0 0.1 GO:0035994 response to muscle stretch(GO:0035994)
0.0 0.2 GO:1902547 regulation of vascular endothelial growth factor signaling pathway(GO:1900746) regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902547)
0.0 0.2 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.2 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.0 0.1 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.1 GO:0090342 regulation of cell aging(GO:0090342)
0.0 0.3 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.4 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.1 GO:0031649 heat generation(GO:0031649) regulation of heat generation(GO:0031650) positive regulation of heat generation(GO:0031652) regulation of phospholipid biosynthetic process(GO:0071071) negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0 1.0 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.8 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.1 GO:0010518 positive regulation of phospholipase activity(GO:0010518) activation of phospholipase D activity(GO:0031584) positive regulation of lipase activity(GO:0060193)
0.0 1.3 GO:0042742 defense response to bacterium(GO:0042742)
0.0 0.6 GO:0009225 nucleotide-sugar metabolic process(GO:0009225)
0.0 0.2 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.1 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.2 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 1.0 GO:0006414 translational elongation(GO:0006414)
0.0 0.5 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.5 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.1 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.0 0.1 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.0 0.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.3 GO:0015671 oxygen transport(GO:0015671)
0.0 0.4 GO:0051923 sulfation(GO:0051923)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 1.3 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.2 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.1 GO:0007569 cell aging(GO:0007569) cellular senescence(GO:0090398)
0.0 0.3 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.0 GO:0071554 cell wall biogenesis(GO:0042546) cell wall macromolecule metabolic process(GO:0044036) cell wall macromolecule biosynthetic process(GO:0044038) cellular component macromolecule biosynthetic process(GO:0070589) cell wall organization or biogenesis(GO:0071554)
0.0 0.7 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 0.3 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.2 GO:0070328 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.0 0.9 GO:0008016 regulation of heart contraction(GO:0008016)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.1 GO:1904103 regulation of convergent extension involved in gastrulation(GO:1904103)
0.0 0.1 GO:0000710 meiotic mismatch repair(GO:0000710)
0.0 0.1 GO:0006026 aminoglycan catabolic process(GO:0006026)
0.0 0.1 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 0.3 GO:0009408 response to heat(GO:0009408)
0.0 0.0 GO:1903723 negative regulation of centriole elongation(GO:1903723)
0.0 0.0 GO:0051876 pigment granule dispersal(GO:0051876)
0.0 0.1 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 0.5 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.0 0.3 GO:0009411 response to UV(GO:0009411)
0.0 0.1 GO:0050820 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.0 0.2 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.1 GO:0044211 CTP salvage(GO:0044211)
0.0 0.6 GO:0060048 cardiac muscle contraction(GO:0060048)
0.0 0.1 GO:1902019 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.1 0.4 GO:0070209 ASTRA complex(GO:0070209)
0.1 1.0 GO:0045095 keratin filament(GO:0045095)
0.1 0.3 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.2 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.1 0.5 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 0.7 GO:0035101 FACT complex(GO:0035101)
0.1 0.5 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.4 GO:0030914 STAGA complex(GO:0030914)
0.1 0.3 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.3 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.6 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.2 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.5 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.5 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.4 GO:0071782 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 0.2 GO:0034657 GID complex(GO:0034657)
0.0 0.2 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.3 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.7 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.2 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.3 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 1.0 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176) cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.2 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.3 GO:0097651 phosphatidylinositol 3-kinase complex, class IB(GO:0005944) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.7 GO:0005657 replication fork(GO:0005657)
0.0 0.4 GO:0031430 M band(GO:0031430)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.2 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.1 GO:0030428 cell septum(GO:0030428)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.2 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.0 0.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 1.7 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 3.4 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.6 GO:0016592 mediator complex(GO:0016592)
0.0 0.3 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.4 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0 0.4 GO:0008305 integrin complex(GO:0008305)
0.0 0.2 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 2.4 GO:0005840 ribosome(GO:0005840)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.2 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) nuclear chromosome, telomeric region(GO:0000784)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0004471 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 0.4 GO:0009041 uridylate kinase activity(GO:0009041)
0.1 1.0 GO:0001130 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.1 0.5 GO:0004649 poly(ADP-ribose) glycohydrolase activity(GO:0004649)
0.1 0.4 GO:0070513 death domain binding(GO:0070513)
0.1 0.3 GO:0004372 glycine hydroxymethyltransferase activity(GO:0004372) serine binding(GO:0070905)
0.1 0.9 GO:0035804 structural constituent of egg coat(GO:0035804)
0.1 0.2 GO:0003721 telomerase RNA reverse transcriptase activity(GO:0003721)
0.1 0.5 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.1 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.4 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.5 GO:0004962 endothelin receptor activity(GO:0004962)
0.1 0.6 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 1.1 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 0.2 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.1 0.8 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.4 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.1 0.4 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 0.4 GO:0034632 retinol transporter activity(GO:0034632)
0.1 0.6 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.4 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.1 0.3 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 0.2 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1 0.3 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184) 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.1 0.3 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.5 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.2 GO:0004408 holocytochrome-c synthase activity(GO:0004408)
0.0 0.3 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 1.7 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.5 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0048030 disaccharide binding(GO:0048030)
0.0 0.2 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.1 GO:0061513 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.1 GO:0031835 neurokinin receptor binding(GO:0031834) substance P receptor binding(GO:0031835)
0.0 0.3 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.2 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.0 0.6 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.3 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.5 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.5 GO:0002020 protease binding(GO:0002020)
0.0 0.2 GO:0038132 neuregulin receptor activity(GO:0038131) neuregulin binding(GO:0038132)
0.0 0.2 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.3 GO:0034452 dynactin binding(GO:0034452)
0.0 0.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.1 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.1 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.4 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.3 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.2 GO:0031779 melanocortin receptor binding(GO:0031779)
0.0 0.3 GO:0031720 haptoglobin binding(GO:0031720)
0.0 0.1 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.0 0.2 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.4 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.0 0.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.0 1.4 GO:0005178 integrin binding(GO:0005178)
0.0 1.0 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.3 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.6 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.2 GO:0016918 retinal binding(GO:0016918)
0.0 0.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 1.0 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 4.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.7 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0 0.3 GO:2001069 glycogen binding(GO:2001069)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.5 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.3 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.5 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.5 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.2 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 1.3 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309) double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.0 0.8 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.2 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0016519 gastric inhibitory peptide receptor activity(GO:0016519)
0.0 0.1 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.1 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.3 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.1 GO:0005536 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.1 GO:0004100 chitin synthase activity(GO:0004100)
0.0 0.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.1 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 2.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.2 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.1 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.2 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.0 GO:0030623 U5 snRNA binding(GO:0030623)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.0 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.0 0.5 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 1.6 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 0.4 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.2 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.8 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.4 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.0 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.4 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.8 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.7 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.2 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.2 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 1.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 PID MYC PATHWAY C-MYC pathway
0.0 0.5 PID AURORA B PATHWAY Aurora B signaling
0.0 0.1 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.3 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.5 PID ATR PATHWAY ATR signaling pathway
0.0 0.5 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.2 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.2 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 0.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 0.5 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.8 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.6 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.9 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.3 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.2 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.5 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.5 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.5 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.4 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.2 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.2 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.4 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.1 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.9 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.2 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.4 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.1 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.8 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.1 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.6 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.2 REACTOME TELOMERE MAINTENANCE Genes involved in Telomere Maintenance
0.0 0.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.5 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.1 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.2 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 0.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha