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PRJNA207719: Tissue specific transcriptome profiling
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Results for ctcf
Z-value: 1.05
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Transcription factors associated with ctcf
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ctcf | dr11_v1_chr18_+_22285992_22286029 | 0.94 | 1.8e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr2_+_56463167 Show fit | 0.53 |
ENSDART00000123392
|
RAB11B, member RAS oncogene family, b |
|
| chr21_+_45626136 Show fit | 0.42 |
ENSDART00000158742
|
interferon regulatory factor 1b |
|
| chr9_-_12594759 Show fit | 0.40 |
ENSDART00000021266
|
transformer 2 beta homolog |
|
| chr18_+_907266 Show fit | 0.40 |
ENSDART00000171729
|
pyruvate kinase M1/2a |
|
| chr20_-_29864390 Show fit | 0.39 |
ENSDART00000161834
ENSDART00000132278 |
ring finger protein 144ab |
|
| chr21_+_17024002 Show fit | 0.39 |
ENSDART00000080628
|
actin related protein 2/3 complex, subunit 3 |
|
| chr9_-_12595003 Show fit | 0.38 |
ENSDART00000184900
|
transformer 2 beta homolog |
|
| chr17_+_6276559 Show fit | 0.37 |
ENSDART00000131075
|
dual specificity phosphatase 23b |
|
| chr5_+_57320113 Show fit | 0.36 |
ENSDART00000036331
|
ATPase H+ transporting V1 subunit G1 |
|
| chr22_-_57177 Show fit | 0.36 |
ENSDART00000163959
|
|
Network of associatons between targets according to the STRING database.
First level regulatory network of ctcf
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.8 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
| 0.0 | 0.4 | GO:0097345 | mitochondrial outer membrane permeabilization(GO:0097345) |
| 0.0 | 0.4 | GO:0050688 | regulation of defense response to virus(GO:0050688) |
| 0.0 | 0.4 | GO:0034314 | Arp2/3 complex-mediated actin nucleation(GO:0034314) |
| 0.1 | 0.3 | GO:0090527 | actin filament reorganization(GO:0090527) |
| 0.0 | 0.3 | GO:0034334 | adherens junction maintenance(GO:0034334) |
| 0.0 | 0.3 | GO:0003404 | optic vesicle morphogenesis(GO:0003404) |
| 0.0 | 0.3 | GO:0033278 | cell proliferation in midbrain(GO:0033278) |
| 0.0 | 0.3 | GO:0021592 | fourth ventricle development(GO:0021592) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284) |
| 0.0 | 0.3 | GO:0051788 | response to misfolded protein(GO:0051788) cellular response to misfolded protein(GO:0071218) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.4 | GO:0005673 | transcription factor TFIIE complex(GO:0005673) |
| 0.0 | 0.4 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
| 0.0 | 0.4 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.0 | 0.4 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 0.0 | 0.4 | GO:0016471 | vacuolar proton-transporting V-type ATPase complex(GO:0016471) |
| 0.1 | 0.3 | GO:0097433 | dense body(GO:0097433) |
| 0.0 | 0.3 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
| 0.0 | 0.3 | GO:0031594 | neuromuscular junction(GO:0031594) |
| 0.0 | 0.2 | GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex(GO:0031464) |
| 0.0 | 0.2 | GO:0089701 | U2AF(GO:0089701) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.4 | GO:0003985 | acetyl-CoA C-acetyltransferase activity(GO:0003985) |
| 0.1 | 0.4 | GO:0004743 | pyruvate kinase activity(GO:0004743) |
| 0.0 | 0.4 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
| 0.1 | 0.3 | GO:0030267 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
| 0.1 | 0.3 | GO:0033829 | O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829) |
| 0.1 | 0.3 | GO:0098973 | structural constituent of postsynaptic actin cytoskeleton(GO:0098973) |
| 0.0 | 0.3 | GO:0001642 | group III metabotropic glutamate receptor activity(GO:0001642) |
| 0.0 | 0.3 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
| 0.0 | 0.3 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
| 0.0 | 0.3 | GO:0001540 | beta-amyloid binding(GO:0001540) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.6 | REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
| 0.0 | 0.4 | REACTOME INSULIN RECEPTOR RECYCLING | Genes involved in Insulin receptor recycling |
| 0.0 | 0.3 | REACTOME FGFR2C LIGAND BINDING AND ACTIVATION | Genes involved in FGFR2c ligand binding and activation |
| 0.0 | 0.3 | REACTOME PRE NOTCH PROCESSING IN GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
| 0.0 | 0.2 | REACTOME PECAM1 INTERACTIONS | Genes involved in PECAM1 interactions |
| 0.0 | 0.2 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.0 | 0.1 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 0.0 | 0.1 | REACTOME AMINE DERIVED HORMONES | Genes involved in Amine-derived hormones |