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PRJNA207719: Tissue specific transcriptome profiling

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Results for clocka+clockb+npas2

Z-value: 2.09

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Transcription factors associated with clocka+clockb+npas2

Gene Symbol Gene ID Gene Info
ENSDARG00000003631 clock circadian regulator b
ENSDARG00000011703 clock circadian regulator a
ENSDARG00000016536 neuronal PAS domain protein 2
ENSDARG00000116993 neuronal PAS domain protein 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
npas2dr11_v1_chr5_+_22791686_22791686-0.977.5e-03Click!
clockadr11_v1_chr20_+_22130284_22130284-0.819.9e-02Click!
clockbdr11_v1_chr1_+_19433004_19433004-0.692.0e-01Click!

Activity profile of clocka+clockb+npas2 motif

Sorted Z-values of clocka+clockb+npas2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_43119698 2.16 ENSDART00000167847
ENSDART00000186962
ENSDART00000187305
eukaryotic translation elongation factor 1 alpha 1, like 1
chr10_+_22034477 1.72 ENSDART00000133304
ENSDART00000134189
ENSDART00000021240
ENSDART00000100526
nucleophosmin 1a
chr14_+_22076596 1.59 ENSDART00000106147
ENSDART00000100278
ENSDART00000131489
solute carrier family 43 (amino acid system L transporter), member 1a
chr24_-_12938922 1.36 ENSDART00000024084
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
chr19_-_47555956 1.30 ENSDART00000114549
actin, alpha, cardiac muscle 1a
chr2_-_42375275 1.25 ENSDART00000026339
GTP binding protein 4
chr8_+_26059677 1.21 ENSDART00000009178
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr5_+_38462121 1.18 ENSDART00000144425
glycolipid transfer protein domain containing 2
chr8_-_21372446 1.18 ENSDART00000061481
ENSDART00000079293
elastase 2 like
chr11_-_16975190 1.12 ENSDART00000122222
succinate-CoA ligase, GDP-forming, beta subunit
chr8_+_23213320 1.04 ENSDART00000032996
ENSDART00000137536
pancreatic progenitor cell differentiation and proliferation factor a
chr20_-_29483514 1.04 ENSDART00000062370
actin, alpha, cardiac muscle 1a
chr10_+_17026870 1.00 ENSDART00000184529
ENSDART00000157480

chr19_+_42983613 0.99 ENSDART00000033724
fatty acid binding protein 3, muscle and heart
chr6_+_50451337 0.97 ENSDART00000155051
myelocytomatosis oncogene homolog
chr22_+_835728 0.91 ENSDART00000003325
DENN/MADD domain containing 2Db
chr6_-_8498908 0.89 ENSDART00000149222
peptidoglycan recognition protein 2
chr12_+_19384615 0.89 ENSDART00000078266
ribosomal L1 domain containing 1
chr22_-_23612854 0.87 ENSDART00000165885
complement factor H like 5
chr21_-_20765338 0.83 ENSDART00000135940
growth hormone receptor b
chr21_+_11969603 0.82 ENSDART00000142247
ENSDART00000140652
motilin-like
chr3_+_18398876 0.81 ENSDART00000141100
ENSDART00000138107
ribosomal protein S2
chr7_-_32021853 0.78 ENSDART00000134521
kinesin family member 18A
chr11_-_37995501 0.77 ENSDART00000192096
solute carrier family 41 (magnesium transporter), member 1
chr23_+_25292147 0.76 ENSDART00000131486
proliferation-associated 2G4, b
chr25_+_28555584 0.76 ENSDART00000157046
si:ch211-190o6.3
chr23_+_17417539 0.75 ENSDART00000182605

chr5_+_19337108 0.74 ENSDART00000089078
acetyl-CoA carboxylase beta
chr22_+_661711 0.74 ENSDART00000113795
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr1_-_52461322 0.73 ENSDART00000083836
si:ch211-217k17.7
chr20_-_49704915 0.72 ENSDART00000189232
cytochrome c oxidase subunit 7A2
chr18_+_15644559 0.72 ENSDART00000061794
nuclear receptor subfamily 1, group H, member 4
chr5_-_32505109 0.72 ENSDART00000188219
N-terminal Xaa-Pro-Lys N-methyltransferase 1
chr5_-_1963498 0.72 ENSDART00000073462
ribosomal protein, large, P0
chr5_-_8817458 0.72 ENSDART00000191098
fibroblast growth factor 10b
chr22_+_661505 0.72 ENSDART00000149460
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr3_+_1015867 0.72 ENSDART00000109912
si:ch1073-464p5.5
chr18_-_19456269 0.71 ENSDART00000060363
ribosomal protein L4
chr2_+_37875789 0.71 ENSDART00000036318
ENSDART00000127679
cerebellin 13
chr17_+_38566717 0.70 ENSDART00000145147
spectrin, beta, erythrocytic
chr21_+_43702016 0.69 ENSDART00000017176
dyskeratosis congenita 1, dyskerin
chr22_+_21317597 0.69 ENSDART00000132605
SHC (Src homology 2 domain containing) transforming protein 2
chr5_-_29534748 0.69 ENSDART00000159587

chr17_-_49407091 0.69 ENSDART00000021950
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b
chr9_+_34996245 0.68 ENSDART00000111437
junctional adhesion molecule 2b
chr2_-_51630555 0.68 ENSDART00000171746
polymeric immunoglobulin receptor
chr24_-_42090635 0.67 ENSDART00000166413
signal sequence receptor, alpha
chr19_-_24555935 0.67 ENSDART00000132660
ENSDART00000162801
polymerase (RNA) III (DNA directed) polypeptide G like a
chr20_+_10544100 0.67 ENSDART00000113927
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr22_-_17489040 0.67 ENSDART00000141286
si:ch211-197g15.6
chr11_-_29946927 0.66 ENSDART00000165182
zgc:113276
chr7_+_6652967 0.65 ENSDART00000102681
purine nucleoside phosphorylase 5a
chr7_+_67467702 0.65 ENSDART00000168460
ENSDART00000170322
ribosomal protein L13
chr10_-_322769 0.65 ENSDART00000165244
v-akt murine thymoma viral oncogene homolog 2, like
chr6_-_52348562 0.64 ENSDART00000142565
ENSDART00000145369
ENSDART00000016890
eukaryotic translation initiation factor 6
chr11_+_29671661 0.64 ENSDART00000024318
ENSDART00000165024
ring finger protein 207a
chr11_-_29946640 0.64 ENSDART00000079175
zgc:113276
chr22_-_5323482 0.64 ENSDART00000145785
sphingosine-1-phosphate receptor 4
chr13_+_15701849 0.63 ENSDART00000003517
tRNA methyltransferase 61A
chr13_-_31370184 0.63 ENSDART00000034829
ribosomal RNA processing 12 homolog
chr3_-_16760923 0.62 ENSDART00000055855
aspartate dehydrogenase domain containing
chr3_-_3398383 0.62 ENSDART00000047865
si:dkey-46g23.2
chr5_+_29714786 0.62 ENSDART00000148314
DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
chr9_+_42270043 0.61 ENSDART00000137435
si:dkey-10c21.1
chr7_-_38644560 0.60 ENSDART00000114934
six-cysteine containing astacin protease 3
chr14_+_22022441 0.60 ENSDART00000149121
cardiotrophin-like cytokine factor 1
chr6_-_49634787 0.60 ENSDART00000188538

chr3_-_34027178 0.60 ENSDART00000170201
ENSDART00000151408
immunoglobulin heavy variable 1-4
immunoglobulin heavy variable 14-1
chr4_-_16824231 0.60 ENSDART00000014007
glycogen synthase 2
chr24_-_38644937 0.59 ENSDART00000170194
solute carrier family 6, member 16b
chr16_+_40954481 0.59 ENSDART00000058587
glycogen synthase kinase binding protein
chr16_-_31919568 0.59 ENSDART00000027364
RNA binding fox-1 homolog 1, like
chr9_+_23770666 0.58 ENSDART00000182493
si:ch211-219a4.3
chr20_+_46660339 0.58 ENSDART00000016530
adenylate cyclase 3b
chr13_-_42306348 0.58 ENSDART00000003706
kynurenine 3-monooxygenase
chr11_+_3959495 0.58 ENSDART00000122953
guanine nucleotide binding protein-like 3 (nucleolar)
chr4_-_16824556 0.58 ENSDART00000165289
ENSDART00000185839
glycogen synthase 2
chr19_-_24555623 0.57 ENSDART00000176022
polymerase (RNA) III (DNA directed) polypeptide G like a
chr22_-_20695237 0.56 ENSDART00000112722
oogenesis-related gene
chr19_+_32166702 0.56 ENSDART00000021798
fatty acid binding protein 11a
chr14_+_14836468 0.56 ENSDART00000166728
si:dkey-102m7.3
chr17_+_53156530 0.56 ENSDART00000126277
ENSDART00000156774
diphthamine biosynthesis 6
chr19_+_20201254 0.56 ENSDART00000010140
insulin-like growth factor 2 mRNA binding protein 3
chr19_+_43123331 0.55 ENSDART00000187836

chr5_-_32505276 0.55 ENSDART00000034705
ENSDART00000187597
N-terminal Xaa-Pro-Lys N-methyltransferase 1
chr17_-_51651631 0.55 ENSDART00000154699
chemokine (C-C motif) receptor 6b
chr11_-_28050559 0.54 ENSDART00000136859
endothelin converting enzyme 1
chr15_+_20239141 0.54 ENSDART00000101152
ENSDART00000152473
serine peptidase inhibitor, Kunitz type, 2
chr16_-_48400639 0.53 ENSDART00000159372
eukaryotic translation initiation factor 3, subunit H, a
chr3_+_16229911 0.53 ENSDART00000121728
ribosomal protein L19
chr7_-_38644287 0.53 ENSDART00000182307
six-cysteine containing astacin protease 3
chr12_+_13091842 0.52 ENSDART00000185477
ENSDART00000181435
ENSDART00000124799
si:ch211-103b1.2
chr16_+_33902006 0.52 ENSDART00000161807
ENSDART00000159474
guanine nucleotide binding protein-like 2 (nucleolar)
chr23_-_29824146 0.52 ENSDART00000020616
zgc:194189
chr5_+_29715040 0.52 ENSDART00000192563
DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
chr10_-_15340362 0.52 ENSDART00000148119
ENSDART00000127277
ENSDART00000154037
ENSDART00000189109
pumilio RNA-binding family member 3
chr16_-_13388821 0.52 ENSDART00000144062
glutamate receptor, ionotropic, N-methyl D-aspartate 2D, b
chr2_+_25839650 0.52 ENSDART00000134077
ENSDART00000140804
eukaryotic translation initiation factor 5A2
chr25_-_30344117 0.52 ENSDART00000167077
protein disulfide isomerase family A, member 3
chr5_+_72194444 0.52 ENSDART00000165436
DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
chr14_+_23518110 0.51 ENSDART00000112930
si:ch211-221f10.2
chr6_+_29305190 0.51 ENSDART00000078647
si:ch211-201h21.5
chr9_-_33328948 0.50 ENSDART00000006948
ribosomal protein L8
chr9_-_56231387 0.50 ENSDART00000149851
ribosomal protein L31
chr21_-_22724980 0.50 ENSDART00000035469
complement component 1, q subcomponent, A chain
chr5_-_16475374 0.50 ENSDART00000134274
ENSDART00000136004
piwi-like RNA-mediated gene silencing 2
chr6_+_3717613 0.50 ENSDART00000184330
Sjogren syndrome antigen B (autoantigen La)
chr4_+_25607743 0.50 ENSDART00000028297
acyl-CoA thioesterase 14
chr15_-_14038227 0.50 ENSDART00000139068
zgc:114130
chr6_-_21189295 0.50 ENSDART00000137136
obscurin-like 1a
chr18_+_40993196 0.50 ENSDART00000115111
si:dkey-283j8.1
chr10_-_373575 0.50 ENSDART00000114487
DM1 protein kinase
chr11_+_12052791 0.49 ENSDART00000158479
si:ch211-156l18.8
chr15_-_17099560 0.49 ENSDART00000101724
v-mos Moloney murine sarcoma viral oncogene homolog
chr21_+_26071874 0.49 ENSDART00000003001
ENSDART00000146573
ribosomal protein L23a
chr19_-_42573219 0.49 ENSDART00000126021
ENSDART00000133695
ENSDART00000131558
zgc:103438
chr13_-_24260609 0.48 ENSDART00000138747
URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
chr3_-_25377163 0.48 ENSDART00000055490
karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
chr20_-_33675676 0.48 ENSDART00000147168
rho-associated, coiled-coil containing protein kinase 2b
chr9_+_20781047 0.48 ENSDART00000139174
family with sequence similarity 46, member C
chr11_-_12800945 0.47 ENSDART00000191178
taxilin gamma
chr23_+_25291891 0.47 ENSDART00000016248
proliferation-associated 2G4, b
chr15_+_25635326 0.47 ENSDART00000135409
ENSDART00000162240
ENSDART00000052645
TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)
chr3_-_58798377 0.47 ENSDART00000161248
si:ch73-281f12.4
chr9_-_33329700 0.47 ENSDART00000147265
ENSDART00000140039
ribosomal protein L8
chr12_-_18898413 0.47 ENSDART00000181281
ENSDART00000121866
desumoylating isopeptidase 1b
chr3_-_18805225 0.47 ENSDART00000133471
ENSDART00000131758
methionine sulfoxide reductase B1a
chr5_+_12836913 0.46 ENSDART00000023101
pescadillo
chr6_-_57476465 0.46 ENSDART00000128065
DEAD (Asp-Glu-Ala-Asp) box polypeptide 27
chr5_-_2689753 0.46 ENSDART00000172699
guanine nucleotide binding protein (G protein), gamma 10
chr1_-_26675969 0.45 ENSDART00000054184
tRNA methyltransferase O
chr3_+_1150348 0.44 ENSDART00000148524
nucleolar protein 12
chr1_+_18550864 0.44 ENSDART00000142515
si:dkey-192k22.2
chr3_-_42981739 0.44 ENSDART00000167844
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K
chr11_-_44194132 0.44 ENSDART00000182954
ENSDART00000111271

chr23_+_16935494 0.44 ENSDART00000143120
si:dkey-147f3.4
chr20_+_25626479 0.44 ENSDART00000143883
phosphoribosyl pyrophosphate amidotransferase
chr1_-_51219965 0.44 ENSDART00000146612
ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
chr9_+_21358941 0.44 ENSDART00000147619
ENSDART00000059402
EEF1A lysine methyltransferase 1
chr3_+_54581987 0.44 ENSDART00000018071
eukaryotic translation initiation factor 3, subunit G
chr11_-_12801157 0.44 ENSDART00000103449
taxilin gamma
chr25_+_16356083 0.44 ENSDART00000125925
ENSDART00000125444
TEA domain family member 1a
chr24_+_34069675 0.44 ENSDART00000143995
si:ch211-190p8.2
chr17_+_24821627 0.44 ENSDART00000112389
WD repeat domain 43
chr1_-_9195629 0.43 ENSDART00000143587
ENSDART00000192174
endoplasmic reticulum to nucleus signaling 2
chr22_-_23591340 0.43 ENSDART00000167024
coagulation factor XIII, B polypeptide
chr7_-_30779575 0.43 ENSDART00000004782
M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
chr8_+_17184602 0.43 ENSDART00000050228
ENSDART00000140531
DIM1 dimethyladenosine transferase 1-like (S. cerevisiae)
chr3_-_58165254 0.42 ENSDART00000093031
SNU13 homolog, small nuclear ribonucleoprotein a (U4/U6.U5)
chr17_-_45370200 0.42 ENSDART00000186208
zinc finger protein 106a
chr2_+_5793908 0.41 ENSDART00000145219
solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1b
chr13_-_31025505 0.41 ENSDART00000137709
WDFY family member 4
chr5_+_37744625 0.41 ENSDART00000014031
D4, zinc and double PHD fingers family 2
chr18_+_40993369 0.41 ENSDART00000141162
si:dkey-283j8.1
chr16_-_34195002 0.41 ENSDART00000054026
regulator of chromosome condensation 1
chr19_+_43579786 0.41 ENSDART00000138404
si:ch211-199g17.2
chr1_+_10297027 0.41 ENSDART00000152562
eukaryotic translation initiation factor 3, subunit F
chr24_-_20016817 0.40 ENSDART00000082201
ENSDART00000189448
solute carrier family 22 member 13b
chr21_-_41838284 0.40 ENSDART00000141067
chaperonin containing TCP1, subunit 6A (zeta 1)
chr11_+_2180072 0.40 ENSDART00000186854
ENSDART00000164839
homeobox C11b
chr22_-_36690742 0.40 ENSDART00000017188
ENSDART00000124698
nucleolin
chr1_-_19764038 0.40 ENSDART00000005733
translation machinery associated 16 homolog
chr20_+_33875256 0.40 ENSDART00000002554
retinoid X receptor, gamma b
chr18_+_38191346 0.40 ENSDART00000052703
nucleobindin 2b
chr8_-_46486009 0.39 ENSDART00000140431
sulfotransferase family 1, cytosolic sulfotransferase 9
chr7_+_1505507 0.39 ENSDART00000161015
NOP10 ribonucleoprotein homolog (yeast)
chr3_-_58798815 0.39 ENSDART00000082920
si:ch73-281f12.4
chr22_+_29991834 0.39 ENSDART00000147728
si:dkey-286j15.3
chr20_+_38257766 0.39 ENSDART00000147485
ENSDART00000149160
chemokine (C-C motif) ligand 38, duplicate 6
chr7_+_32021982 0.39 ENSDART00000173848
methyltransferase like 15
chr5_+_13870340 0.39 ENSDART00000160690
hexokinase 2
chr14_+_30774515 0.39 ENSDART00000191666
atlastin 3
chr2_+_25839940 0.39 ENSDART00000139927
eukaryotic translation initiation factor 5A2
chr2_+_45191049 0.39 ENSDART00000165392
chemokine (C-C motif) ligand 20a, duplicate 3
chr6_-_18531349 0.39 ENSDART00000160693
ENSDART00000169780
UTP6, small subunit (SSU) processome component, homolog (yeast)
chr5_-_24270989 0.38 ENSDART00000146251
si:ch211-137i24.12
chr14_+_6423973 0.38 ENSDART00000051556
ATP-binding cassette, sub-family A (ABC1), member 1B
chr8_+_44783424 0.38 ENSDART00000025875
si:ch1073-459j12.1
chr12_+_2677303 0.38 ENSDART00000093113
anthrax toxin receptor 1c
chr1_-_26676391 0.38 ENSDART00000152492
tRNA methyltransferase O
chr15_-_34930727 0.38 ENSDART00000179723
DEAH (Asp-Glu-Ala-His) box polypeptide 16
chr13_+_13930263 0.38 ENSDART00000079154
ribose 5-phosphate isomerase A (ribose 5-phosphate epimerase)
chr5_+_27488975 0.38 ENSDART00000123635
secreted frizzled-related protein 1a
chr22_+_9751117 0.38 ENSDART00000121827

chr10_+_17714866 0.38 ENSDART00000039969
solute carrier family 20 (phosphate transporter), member 1b
chr3_+_22375596 0.38 ENSDART00000188243
ENSDART00000181506
Rho GTPase activating protein 27, like
chr12_-_21684197 0.37 ENSDART00000152999
ENSDART00000153109
ENSDART00000148698
essential meiotic structure-specific endonuclease 1
chr3_-_56871330 0.37 ENSDART00000014103
zgc:112148
chr5_-_33959868 0.37 ENSDART00000143652
zgc:63972
chr13_-_293250 0.37 ENSDART00000138581
chitin synthase 1
chr25_+_19733704 0.37 ENSDART00000145334
ENSDART00000138946
ENSDART00000138851
zgc:101783
chr9_+_12894578 0.37 ENSDART00000081270
si:ch211-167j6.5
chr19_+_48359259 0.37 ENSDART00000167353
shugoshin 1
chr8_+_44358443 0.37 ENSDART00000189130
ENSDART00000189212

chr9_+_29985010 0.37 ENSDART00000020743
cms1 ribosomal small subunit homolog (yeast)
chr19_+_16015881 0.37 ENSDART00000187135
CTP synthase 1a
chr13_+_15702142 0.37 ENSDART00000135960
tRNA methyltransferase 61A
chr5_-_67499279 0.37 ENSDART00000128050
si:dkey-251i10.3
chr12_+_29240124 0.37 ENSDART00000053761
ENSDART00000130172
BMS1 ribosome biogenesis factor
chr12_+_23892972 0.37 ENSDART00000152852
supervillin a

Network of associatons between targets according to the STRING database.

First level regulatory network of clocka+clockb+npas2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.4 1.3 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.4 2.3 GO:0003272 endocardial cushion formation(GO:0003272)
0.3 1.4 GO:0071548 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401) short-chain fatty acid catabolic process(GO:0019626) response to dexamethasone(GO:0071548)
0.3 0.9 GO:0098581 detection of biotic stimulus(GO:0009595) detection of bacterium(GO:0016045) detection of other organism(GO:0098543) detection of external biotic stimulus(GO:0098581)
0.2 0.6 GO:0042256 mature ribosome assembly(GO:0042256) assembly of large subunit precursor of preribosome(GO:1902626)
0.2 1.4 GO:0045901 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.2 0.7 GO:0060437 lung growth(GO:0060437) secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.2 0.7 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.2 0.5 GO:1905133 meiotic cell cycle phase transition(GO:0044771) metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.2 1.5 GO:0006177 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.1 0.6 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 0.5 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.1 1.2 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.5 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.1 0.6 GO:0043420 anthranilate metabolic process(GO:0043420)
0.1 0.3 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.1 0.3 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.1 1.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.1 1.3 GO:0009303 rRNA transcription(GO:0009303)
0.1 0.6 GO:0048260 positive regulation of receptor-mediated endocytosis(GO:0048260) protein localization to early endosome(GO:1902946)
0.1 0.5 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.1 0.6 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.4 GO:0071962 mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.1 0.4 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.1 0.3 GO:0090069 regulation of ribosome biogenesis(GO:0090069)
0.1 0.4 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.1 0.6 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 0.8 GO:0000479 endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.1 0.5 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 0.2 GO:0071514 genetic imprinting(GO:0071514)
0.1 0.3 GO:0048014 Tie signaling pathway(GO:0048014)
0.1 0.2 GO:0006585 dopamine biosynthetic process from tyrosine(GO:0006585) dopamine biosynthetic process(GO:0042416)
0.1 0.3 GO:0051661 maintenance of centrosome location(GO:0051661)
0.1 2.1 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.1 0.4 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.1 0.4 GO:0006031 chitin biosynthetic process(GO:0006031) glucosamine-containing compound biosynthetic process(GO:1901073)
0.1 0.3 GO:0010755 regulation of plasminogen activation(GO:0010755)
0.1 0.8 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 0.8 GO:0060416 growth hormone receptor signaling pathway(GO:0060396) response to growth hormone(GO:0060416) cellular response to growth hormone stimulus(GO:0071378)
0.1 0.6 GO:0009435 NAD biosynthetic process(GO:0009435)
0.1 0.3 GO:0072149 glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.1 0.4 GO:0001678 cellular glucose homeostasis(GO:0001678)
0.1 0.2 GO:0060912 cardiac cell fate specification(GO:0060912)
0.1 0.2 GO:0031590 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.1 0.2 GO:0009957 epidermal cell fate specification(GO:0009957)
0.1 0.4 GO:0006356 regulation of transcription from RNA polymerase I promoter(GO:0006356) positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.1 0.3 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 0.3 GO:0048903 anterior lateral line neuromast hair cell differentiation(GO:0048903)
0.1 1.2 GO:0009749 response to carbohydrate(GO:0009743) response to hexose(GO:0009746) response to glucose(GO:0009749) response to monosaccharide(GO:0034284)
0.1 0.4 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.1 0.2 GO:0006116 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.1 0.6 GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
0.1 1.2 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 0.3 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.1 0.2 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.1 0.3 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.1 0.6 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.1 0.2 GO:0071051 U4 snRNA 3'-end processing(GO:0034475) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.1 0.3 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.0 9.2 GO:0042254 ribosome biogenesis(GO:0042254)
0.0 1.6 GO:0072310 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.7 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 1.5 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.5 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 0.7 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.0 0.3 GO:0019184 nonribosomal peptide biosynthetic process(GO:0019184)
0.0 0.4 GO:1901998 toxin transport(GO:1901998)
0.0 0.9 GO:0006270 DNA replication initiation(GO:0006270)
0.0 1.3 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0051095 regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096)
0.0 0.1 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.4 GO:0033700 phospholipid efflux(GO:0033700)
0.0 0.2 GO:0019474 lysine catabolic process(GO:0006554) L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.0 0.4 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.5 GO:0016486 peptide hormone processing(GO:0016486)
0.0 1.0 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 1.8 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.2 GO:0030576 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576)
0.0 0.1 GO:1990575 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.0 0.1 GO:0071634 regulation of natural killer cell activation(GO:0032814) positive regulation of natural killer cell activation(GO:0032816) regulation of transforming growth factor beta production(GO:0071634) negative regulation of transforming growth factor beta production(GO:0071635)
0.0 0.1 GO:0030224 monocyte differentiation(GO:0030224)
0.0 0.3 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.8 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.1 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 1.1 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 1.8 GO:0006414 translational elongation(GO:0006414)
0.0 1.3 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.1 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.3 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.4 GO:0032094 response to food(GO:0032094)
0.0 0.2 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.5 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.0 0.6 GO:1901888 regulation of cell junction assembly(GO:1901888)
0.0 0.5 GO:0008354 germ cell migration(GO:0008354)
0.0 0.4 GO:0019835 cytolysis(GO:0019835)
0.0 0.2 GO:1900407 regulation of cellular response to oxidative stress(GO:1900407)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.3 GO:0009086 methionine biosynthetic process(GO:0009086)
0.0 0.1 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.0 0.1 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 1.4 GO:0006958 humoral immune response mediated by circulating immunoglobulin(GO:0002455) complement activation, classical pathway(GO:0006958)
0.0 0.2 GO:0042987 beta-amyloid formation(GO:0034205) amyloid precursor protein catabolic process(GO:0042987)
0.0 0.2 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 1.0 GO:0035272 exocrine pancreas development(GO:0031017) exocrine system development(GO:0035272)
0.0 0.1 GO:0070131 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
0.0 0.2 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.2 GO:0030719 P granule organization(GO:0030719)
0.0 0.1 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.9 GO:0030593 neutrophil chemotaxis(GO:0030593)
0.0 0.2 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.0 1.2 GO:0051693 actin filament capping(GO:0051693)
0.0 0.4 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.2 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.0 0.8 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.1 GO:1902024 L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.0 0.1 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.0 0.1 GO:0016038 absorption of visible light(GO:0016038)
0.0 0.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.1 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.0 0.4 GO:0035329 hippo signaling(GO:0035329)
0.0 0.7 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.4 GO:0051923 sulfation(GO:0051923)
0.0 0.3 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.7 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.1 GO:0032447 tRNA wobble position uridine thiolation(GO:0002143) protein urmylation(GO:0032447)
0.0 0.1 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 0.7 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 0.2 GO:0006000 fructose metabolic process(GO:0006000) fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:1904105 positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.0 0.3 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.0 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.7 GO:0006171 cAMP biosynthetic process(GO:0006171)
0.0 1.2 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.4 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 4.1 GO:0043043 peptide biosynthetic process(GO:0043043)
0.0 0.4 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.1 GO:0015864 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.0 0.1 GO:0097066 response to thyroid hormone(GO:0097066)
0.0 0.1 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 1.3 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.2 GO:0072599 protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.0 0.4 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 0.1 GO:0006166 purine ribonucleoside salvage(GO:0006166) AMP salvage(GO:0044209)
0.0 0.1 GO:0032475 otolith formation(GO:0032475)
0.0 0.2 GO:0071173 mitotic spindle assembly checkpoint(GO:0007094) spindle checkpoint(GO:0031577) negative regulation of mitotic metaphase/anaphase transition(GO:0045841) spindle assembly checkpoint(GO:0071173) mitotic spindle checkpoint(GO:0071174)
0.0 0.1 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.3 GO:0051180 vitamin transport(GO:0051180)
0.0 0.4 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 0.1 GO:0022401 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) G-protein coupled receptor internalization(GO:0002031) negative adaptation of signaling pathway(GO:0022401) adaptation of signaling pathway(GO:0023058)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0042709 succinate-CoA ligase complex(GO:0042709)
0.3 1.4 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.2 0.8 GO:0070195 growth hormone receptor complex(GO:0070195)
0.2 1.0 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.2 0.8 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.2 0.5 GO:0070545 PeBoW complex(GO:0070545)
0.1 2.3 GO:0005869 dynactin complex(GO:0005869)
0.1 0.4 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.6 GO:0097268 cytoophidium(GO:0097268)
0.1 0.4 GO:0034457 Mpp10 complex(GO:0034457)
0.1 0.7 GO:0008091 spectrin(GO:0008091)
0.1 0.4 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 0.5 GO:1990923 PET complex(GO:1990923)
0.1 2.4 GO:0030686 90S preribosome(GO:0030686)
0.1 1.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.4 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.1 0.3 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 4.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 0.9 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.2 GO:0033391 chromatoid body(GO:0033391)
0.1 0.4 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.8 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.4 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.1 0.3 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 0.5 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 0.5 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.2 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.0 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.4 GO:0030428 cell septum(GO:0030428)
0.0 10.7 GO:0005730 nucleolus(GO:0005730)
0.0 0.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.2 GO:0070724 BMP receptor complex(GO:0070724)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.4 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.6 GO:0042555 MCM complex(GO:0042555)
0.0 1.2 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.5 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.4 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.0 0.3 GO:0014704 intercalated disc(GO:0014704)
0.0 1.4 GO:0005643 nuclear pore(GO:0005643)
0.0 0.2 GO:0032797 SMN complex(GO:0032797)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.2 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.9 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.8 GO:0022626 cytosolic ribosome(GO:0022626)
0.0 0.3 GO:0015030 Cajal body(GO:0015030)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.0 0.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.1 GO:0032019 mitochondrial cloud(GO:0032019)
0.0 0.1 GO:0045095 keratin filament(GO:0045095)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.3 GO:0043596 nuclear replication fork(GO:0043596)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.2 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.4 1.1 GO:0004775 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775) succinate-CoA ligase (GDP-forming) activity(GO:0004776)
0.3 0.9 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.3 1.2 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.3 1.8 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426)
0.2 0.7 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.2 1.3 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.2 0.8 GO:0034511 U3 snoRNA binding(GO:0034511)
0.2 0.8 GO:0004903 growth hormone receptor activity(GO:0004903)
0.2 0.7 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 0.6 GO:0003883 CTP synthase activity(GO:0003883)
0.1 0.4 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1 0.5 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.1 0.7 GO:0032052 bile acid binding(GO:0032052)
0.1 0.7 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 0.5 GO:0033745 L-methionine-(R)-S-oxide reductase activity(GO:0033745)
0.1 0.6 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.4 GO:0005461 UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.1 0.5 GO:1990518 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.1 0.7 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 0.4 GO:0033204 ribonuclease P RNA binding(GO:0033204)
0.1 0.4 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 0.2 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.1 0.2 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1 0.6 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 0.7 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.1 0.2 GO:0004422 hypoxanthine phosphoribosyltransferase activity(GO:0004422)
0.1 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 0.7 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.1 3.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 1.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.4 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.3 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 0.5 GO:0034584 piRNA binding(GO:0034584)
0.1 0.5 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.1 0.7 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.8 GO:0030515 snoRNA binding(GO:0030515)
0.1 0.2 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.1 0.6 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.1 0.2 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.9 GO:0070122 isopeptidase activity(GO:0070122)
0.0 0.1 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.0 0.4 GO:0004100 chitin synthase activity(GO:0004100)
0.0 1.9 GO:0019843 rRNA binding(GO:0019843)
0.0 0.2 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.0 0.4 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.1 GO:0034618 arginine binding(GO:0034618)
0.0 0.3 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.6 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 1.1 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 1.7 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.5 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.6 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 0.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.0 0.7 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.1 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.0 0.5 GO:0031726 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.0 0.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 2.5 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.5 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 0.8 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.1 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.4 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.3 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.0 0.1 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.5 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.9 GO:0051020 GTPase binding(GO:0051020)
0.0 0.2 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.1 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.0 0.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.8 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.3 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 3.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.5 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.6 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.1 GO:0004960 thromboxane receptor activity(GO:0004960)
0.0 0.6 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.1 GO:0003913 DNA photolyase activity(GO:0003913)
0.0 0.1 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.1 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.0 0.6 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0 0.9 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 2.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0043560 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.0 0.2 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.6 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.5 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 2.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.1 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.3 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:0005165 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.0 1.4 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0004001 adenosine kinase activity(GO:0004001)
0.0 0.3 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.1 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.5 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 0.5 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.0 GO:0017050 D-erythro-sphingosine kinase activity(GO:0017050)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.6 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.5 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.1 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.4 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.1 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.7 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.9 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.3 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.6 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 1.1 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 1.7 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 6.4 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.0 0.7 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.7 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.8 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.5 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.6 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.6 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.5 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.7 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.8 REACTOME KINESINS Genes involved in Kinesins
0.0 1.3 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.7 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.7 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.2 REACTOME ION CHANNEL TRANSPORT Genes involved in Ion channel transport
0.0 0.9 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.5 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.5 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.5 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.4 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.5 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.4 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.3 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.3 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.2 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 0.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.3 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 0.7 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.1 REACTOME OPSINS Genes involved in Opsins