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PRJNA207719: Tissue specific transcriptome profiling
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Results for cebpb
Z-value: 1.22
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Transcription factors associated with cebpb
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| cebpb | dr11_v1_chr8_-_28449782_28449782 | 0.53 | 3.6e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr20_+_23440632 Show fit | 1.96 |
ENSDART00000180685
ENSDART00000042820 |
si:dkey-90m5.4 |
|
| chr5_-_63509581 Show fit | 1.73 |
ENSDART00000097325
|
complement component 5 |
|
| chr14_+_21106444 Show fit | 1.33 |
ENSDART00000075744
ENSDART00000132363 |
aldolase b, fructose-bisphosphate |
|
| chr14_+_16345003 Show fit | 1.32 |
ENSDART00000003040
ENSDART00000165193 |
intelectin 3 |
|
| chr14_+_21107032 Show fit | 1.26 |
ENSDART00000138319
ENSDART00000139103 ENSDART00000184735 |
aldolase b, fructose-bisphosphate |
|
| chr9_-_32847642 Show fit | 1.11 |
ENSDART00000121506
|
hemopexin |
|
| chr8_-_50147948 Show fit | 1.08 |
ENSDART00000149010
|
haptoglobin |
|
| chr6_+_21202639 Show fit | 1.03 |
ENSDART00000083126
|
cell death-inducing DFFA-like effector c |
|
| chr21_+_20901505 Show fit | 1.02 |
ENSDART00000132741
|
complement component 7b |
|
| chr16_-_21785261 Show fit | 1.02 |
ENSDART00000078858
|
si:ch73-86n18.1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of cebpb
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.3 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
| 0.0 | 1.6 | GO:0010951 | negative regulation of endopeptidase activity(GO:0010951) |
| 0.1 | 1.4 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
| 0.2 | 1.0 | GO:0032367 | intracellular cholesterol transport(GO:0032367) |
| 0.1 | 1.0 | GO:0045807 | positive regulation of endocytosis(GO:0045807) |
| 0.0 | 1.0 | GO:0019835 | cytolysis(GO:0019835) |
| 0.0 | 0.9 | GO:0046686 | response to cadmium ion(GO:0046686) |
| 0.0 | 0.9 | GO:0048246 | macrophage chemotaxis(GO:0048246) |
| 0.0 | 0.9 | GO:1904029 | regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029) |
| 0.1 | 0.8 | GO:0002523 | leukocyte migration involved in inflammatory response(GO:0002523) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.1 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.1 | 1.0 | GO:0005579 | membrane attack complex(GO:0005579) |
| 0.3 | 0.8 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.2 | 0.7 | GO:0097134 | cyclin E1-CDK2 complex(GO:0097134) |
| 0.0 | 0.4 | GO:0016442 | RISC complex(GO:0016442) RNAi effector complex(GO:0031332) |
| 0.1 | 0.3 | GO:0035339 | SPOTS complex(GO:0035339) |
| 0.1 | 0.2 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
| 0.0 | 0.2 | GO:0005850 | eukaryotic translation initiation factor 2 complex(GO:0005850) |
| 0.0 | 0.2 | GO:0042720 | mitochondrial inner membrane peptidase complex(GO:0042720) |
| 0.0 | 0.2 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.7 | GO:0004866 | endopeptidase inhibitor activity(GO:0004866) |
| 0.3 | 2.6 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
| 0.0 | 1.5 | GO:0003823 | antigen binding(GO:0003823) |
| 0.1 | 1.3 | GO:0070492 | oligosaccharide binding(GO:0070492) |
| 0.2 | 1.0 | GO:0005153 | interleukin-8 receptor binding(GO:0005153) |
| 0.0 | 1.0 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
| 0.0 | 1.0 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 0.3 | 0.9 | GO:0004736 | pyruvate carboxylase activity(GO:0004736) |
| 0.1 | 0.8 | GO:0019238 | cyclohydrolase activity(GO:0019238) |
| 0.2 | 0.7 | GO:0004372 | glycine hydroxymethyltransferase activity(GO:0004372) serine binding(GO:0070905) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.9 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 1.2 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 0.9 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.0 | 0.8 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.0 | 0.7 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.0 | 0.6 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.0 | 0.6 | PID ATF2 PATHWAY | ATF-2 transcription factor network |
| 0.0 | 0.4 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.0 | 0.3 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.6 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.1 | 1.8 | REACTOME COMPLEMENT CASCADE | Genes involved in Complement cascade |
| 0.0 | 0.9 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.1 | 0.8 | REACTOME PYRIMIDINE CATABOLISM | Genes involved in Pyrimidine catabolism |
| 0.1 | 0.8 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.0 | 0.7 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 0.0 | 0.7 | REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
| 0.1 | 0.6 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.0 | 0.6 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |
| 0.0 | 0.6 | REACTOME ACTIVATION OF GENES BY ATF4 | Genes involved in Activation of Genes by ATF4 |