ISMARA results: bhlhe40

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PRJNA207719: Tissue specific transcriptome profiling

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Results for bhlhe40

Z-value: 0.44

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Transcription factors associated with bhlhe40

Gene Symbol	Gene ID	Gene Info
bhlhe40 NCBI UniProt	ENSDARG00000004060	basic helix-loop-helix family, member e40

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
bhlhe40	dr11_v1_chr11_-_35763323_35763323	0.36	5.5e-01	Click!

Activity profile of bhlhe40 motif

Sorted Z-values of bhlhe40 motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr10_+_5268054 Show fit	0.22	ENSDART00000114491	ror2 NCBI UniProt Show fit	receptor tyrosine kinase-like orphan receptor 2
chr7_-_67214972 Show fit	0.21	ENSDART00000156861	swap70a NCBI UniProt Show fit	switching B cell complex subunit SWAP70a
chr24_+_7631797 Show fit	0.19	ENSDART00000187464	cavin1b NCBI UniProt Show fit	caveolae associated protein 1b
chr9_+_6587364 Show fit	0.19	ENSDART00000122279	fhl2a NCBI UniProt Show fit	four and a half LIM domains 2a
chr5_-_4532516 Show fit	0.16	ENSDART00000192398	cst14b.1 NCBI UniProt Show fit	cystatin 14b, tandem duplicate 1
chr10_-_15644904 Show fit	0.14	ENSDART00000138389 ENSDART00000101191 ENSDART00000186559 ENSDART00000122170	smc5 NCBI UniProt Show fit	structural maintenance of chromosomes 5
chr13_+_7164345 Show fit	0.12	ENSDART00000022051	gins1 NCBI UniProt Show fit	GINS complex subunit 1 (Psf1 homolog)
chr21_-_5393125 Show fit	0.12	ENSDART00000146061	psmd5 NCBI UniProt Show fit	proteasome 26S subunit, non-ATPase 5
chr15_-_28596507 Show fit	0.12	ENSDART00000156800	si:ch211-225b7.5 NCBI UniProt Show fit	si:ch211-225b7.5
chr17_+_25331576 Show fit	0.11	ENSDART00000157309	tmem54a NCBI UniProt Show fit	transmembrane protein 54a

Showing 1 to 10 of 116 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of bhlhe40

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Total log-likelihood	Term	Description
0.2	GO:0006361	transcription initiation from RNA polymerase I promoter(GO:0006361)
0.1	GO:1990519	pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.1	GO:1901207	regulation of heart looping(GO:1901207)
0.1	GO:0097033	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0	GO:0044878	abscission(GO:0009838) mitotic cytokinesis checkpoint(GO:0044878)
0.0	GO:0019242	methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)

Showing 1 to 6 of 6 entries

Gene overrepresentation in cellular component category:

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Total log-likelihood	Term	Description
0.1	GO:0000811	GINS complex(GO:0000811)
0.1	GO:0030915	Smc5-Smc6 complex(GO:0030915)
0.1	GO:0035301	Hedgehog signaling complex(GO:0035301)
0.1	GO:0000439	core TFIIH complex(GO:0000439)

Showing 1 to 4 of 4 entries

Gene overrepresentation in molecular function category:

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Total log-likelihood	Term	Description
0.2	GO:0042134	rRNA primary transcript binding(GO:0042134)
0.1	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310) L-methionine-(R)-S-oxide reductase activity(GO:0033745)
0.1	GO:0015218	pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.0	GO:0004807	triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)

Showing 1 to 5 of 5 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.2	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA

Showing 1 to 1 of 1 entries

Results for bhlhe40

Z-value: 0.44

Motif logo

Transcription factors associated with bhlhe40

Activity-expression correlation:

Activity profile of bhlhe40 motif

Sorted Z-values of bhlhe40 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of bhlhe40

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: