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PRJNA207719: Tissue specific transcriptome profiling

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Results for bhlha15_bhlhe23+si:ch211-196c10.13_bhlhe22

Z-value: 1.37

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Transcription factors associated with bhlha15_bhlhe23+si:ch211-196c10.13_bhlhe22

Gene Symbol Gene ID Gene Info
bhlha15
ENSDARG00000045166 basic helix-loop-helix family, member a15
bhlhe23
ENSDARG00000037588 basic helix-loop-helix family, member e23
si_ch211-196c10.13
ENSDARG00000096756 si_ch211-196c10.13
bhlhe22
ENSDARG00000058039 basic helix-loop-helix family, member e22

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
bhlhe22dr11_v1_chr24_+_24461341_244613410.983.0e-03Click!
bhlhe23dr11_v1_chr23_-_17657348_176573480.976.5e-03Click!
si:ch211-196c10.13dr11_v1_chr8_+_23142946_231429460.951.2e-02Click!
bhlha15dr11_v1_chr12_+_17754859_177548590.464.4e-01Click!

Activity profile of bhlha15_bhlhe23+si:ch211-196c10.13_bhlhe22 motif

Sorted Z-values of bhlha15_bhlhe23+si:ch211-196c10.13_bhlhe22 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr21_+_11468642 2.43 ENSDART00000041869
grin1a
glutamate receptor, ionotropic, N-methyl D-aspartate 1a
chr2_-_27775236 2.41 ENSDART00000187983
XKR4
zgc:123035
chr2_-_27774783 2.25 ENSDART00000161864
XKR4
zgc:123035
chr14_-_4682114 2.25 ENSDART00000014454
gabra4
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 4
chr4_-_8882572 2.23 ENSDART00000190060
mpped1
metallophosphoesterase domain containing 1
chr10_+_22012389 2.16 ENSDART00000035188
kcnip1b
Kv channel interacting protein 1 b
chr14_-_4556896 2.04 ENSDART00000044678
ENSDART00000192863
GABRA2
gamma-aminobutyric acid type A receptor alpha2 subunit
chr5_-_27994679 1.61 ENSDART00000132740
ppp3cca
protein phosphatase 3, catalytic subunit, gamma isozyme, a
chr10_-_31440500 1.60 ENSDART00000024778
robo3
roundabout, axon guidance receptor, homolog 3 (Drosophila)
chr1_-_16507812 1.55 ENSDART00000169081
mtmr7b
myotubularin related protein 7b
chr14_+_25817246 1.49 ENSDART00000136733
glra1
glycine receptor, alpha 1
chr12_-_14922955 1.48 ENSDART00000002078
neurod2
neurogenic differentiation 2
chr12_+_24562667 1.44 ENSDART00000056256
nrxn1a
neurexin 1a
chr19_-_7406933 1.42 ENSDART00000151137
oxr1b
oxidation resistance 1b
chr8_-_39952727 1.24 ENSDART00000181310
cabp1a
calcium binding protein 1a
chr13_+_31285660 1.24 ENSDART00000148352
gdf10a
growth differentiation factor 10a
chr23_-_21453614 1.23 ENSDART00000079274
her4.1
hairy-related 4, tandem duplicate 1
chr4_+_15968483 1.22 ENSDART00000101575
si:dkey-117n7.5
si:dkey-117n7.5
chr14_+_25816874 1.19 ENSDART00000005499
glra1
glycine receptor, alpha 1
chr15_+_15856178 1.17 ENSDART00000080338
dusp14
dual specificity phosphatase 14
chr2_-_39036604 1.15 ENSDART00000129963
rbp1
retinol binding protein 1b, cellular
chr14_+_31618982 1.08 ENSDART00000026195
slc9a6a
solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6a
chr20_-_31252809 1.03 ENSDART00000137236
hpcal1
hippocalcin-like 1
chr2_-_5074812 1.00 ENSDART00000163728
dlg1l
discs, large (Drosophila) homolog 1, like
chr4_+_12617108 0.96 ENSDART00000134362
ENSDART00000112860
lmo3
LIM domain only 3
chr6_+_54142311 0.88 ENSDART00000154115
hmga1b
high mobility group AT-hook 1b
chr22_-_18116635 0.87 ENSDART00000005724
ncanb
neurocan b
chr12_-_3753131 0.74 ENSDART00000129668
fam57bb
family with sequence similarity 57, member Bb
chr13_-_24311628 0.73 ENSDART00000004420
rab4a
RAB4a, member RAS oncogene family
chr13_+_15581270 0.73 ENSDART00000189880
ENSDART00000190067
ENSDART00000041293
mark3a
MAP/microtubule affinity-regulating kinase 3a
chr8_-_22660678 0.71 ENSDART00000181258
iqsec2a
IQ motif and Sec7 domain 2a
chr23_+_21544227 0.71 ENSDART00000140253
arhgef10lb
Rho guanine nucleotide exchange factor (GEF) 10-like b
chr13_+_11439486 0.64 ENSDART00000138312
zbtb18
zinc finger and BTB domain containing 18
chr15_-_14486534 0.57 ENSDART00000179368
numbl
numb homolog (Drosophila)-like
chr11_-_34521342 0.56 ENSDART00000114004
pik3ca
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
chr10_-_23358357 0.53 ENSDART00000135475
cadm2a
cell adhesion molecule 2a
chr20_+_34326874 0.52 ENSDART00000061659
ivns1abpa
influenza virus NS1A binding protein a
chr19_+_1184878 0.51 ENSDART00000163539
scrt1a
scratch family zinc finger 1a
chr13_+_28821841 0.50 ENSDART00000179900
CU639469.1

chr14_+_36521553 0.50 ENSDART00000136233
TENM3
si:dkey-237h12.3
chr5_-_25576462 0.50 ENSDART00000165147
si:dkey-229d2.4
si:dkey-229d2.4
chr17_-_42218652 0.49 ENSDART00000081396
ENSDART00000190007
nkx2.2a
NK2 homeobox 2a
chr1_-_10847753 0.48 ENSDART00000141052
dmd
dystrophin
chr2_-_42558549 0.46 ENSDART00000025997
dip2cb
disco-interacting protein 2 homolog Cb
chr5_-_24245218 0.45 ENSDART00000042481
phf23a
PHD finger protein 23a
chr17_+_28882977 0.44 ENSDART00000153937
prkd1
protein kinase D1
chr20_-_1265562 0.44 ENSDART00000189866
lats1
large tumor suppressor kinase 1
chr13_-_31441042 0.42 ENSDART00000076571
rtn1a
reticulon 1a
chr19_-_21766461 0.40 ENSDART00000104279
znf516
zinc finger protein 516
chr20_-_34028967 0.39 ENSDART00000153408
ENSDART00000033817
scyl3
SCY1-like, kinase-like 3
chr20_-_8365244 0.39 ENSDART00000167102
dab1a
Dab, reelin signal transducer, homolog 1a (Drosophila)
chr22_+_11857356 0.38 ENSDART00000179540
mras
muscle RAS oncogene homolog
chr23_+_23658474 0.38 ENSDART00000162838
agrn
agrin
chr1_-_43712120 0.37 ENSDART00000074600
SLC9B2
si:dkey-162b23.4
chr3_+_50310684 0.36 ENSDART00000112152
gas7a
growth arrest-specific 7a
chr18_+_12147971 0.36 ENSDART00000162067
ENSDART00000168386
fgd4a
FYVE, RhoGEF and PH domain containing 4a
chr4_+_20318127 0.35 ENSDART00000028856
ENSDART00000132909
cacna1c
calcium channel, voltage-dependent, L type, alpha 1C subunit
chr19_-_24125457 0.35 ENSDART00000080632
zgc:64022
zgc:64022
chr1_-_17711636 0.34 ENSDART00000148322
ENSDART00000122670
ufsp2
ufm1-specific peptidase 2
chr8_-_51507144 0.34 ENSDART00000024882
ENSDART00000135166
fgfr1a
fibroblast growth factor receptor 1a
chr22_-_14475927 0.34 ENSDART00000135768
lrp1ba
low density lipoprotein receptor-related protein 1Ba
chr9_+_38168012 0.33 ENSDART00000102445
clasp1a
cytoplasmic linker associated protein 1a
chr7_-_31938938 0.32 ENSDART00000132353
bdnf
brain-derived neurotrophic factor
chr24_+_2801765 0.29 ENSDART00000172385
LYRM4
si:ch211-152c8.4
chr4_+_5796761 0.29 ENSDART00000164854
si:ch73-352p4.8
si:ch73-352p4.8
chr1_+_42874410 0.27 ENSDART00000153506
ctnna2
catenin (cadherin-associated protein), alpha 2
chr21_-_25601648 0.25 ENSDART00000042578
efemp2b
EGF containing fibulin extracellular matrix protein 2b
chr23_-_4019699 0.25 ENSDART00000159780
slc9a8
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr13_+_31286076 0.25 ENSDART00000142725
gdf10a
growth differentiation factor 10a
chr19_-_15855427 0.24 ENSDART00000133059
cited4a
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4a
chr18_-_14836862 0.23 ENSDART00000124843
mtss1la
metastasis suppressor 1-like a
chr13_+_30421472 0.23 ENSDART00000143569
zmiz1a
zinc finger, MIZ-type containing 1a
chr2_-_32551178 0.23 ENSDART00000145603
smarcd3a
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3a
chr15_+_32297441 0.22 ENSDART00000153657
trim3a
tripartite motif containing 3a
chr20_+_36730049 0.22 ENSDART00000045948
ncoa1
nuclear receptor coactivator 1
chr14_+_23874062 0.21 ENSDART00000172149
sh3rf2
SH3 domain containing ring finger 2
chr22_-_17052381 0.21 ENSDART00000138382
nfia
nuclear factor I/A
chr4_+_14360372 0.21 ENSDART00000007103
nuak1a
NUAK family, SNF1-like kinase, 1a
chr10_-_7347311 0.21 ENSDART00000168885
nrg1
neuregulin 1
chr3_-_24909245 0.21 ENSDART00000178321
SHISA8
shisa family member 8
chr7_+_41421998 0.19 ENSDART00000083967
chpf2
chondroitin polymerizing factor 2
chr6_+_7553085 0.18 ENSDART00000150939
ENSDART00000151114
myh10
myosin, heavy chain 10, non-muscle
chr11_+_5499661 0.17 ENSDART00000027850
slc35e1
solute carrier family 35, member E1
chr6_-_36182115 0.17 ENSDART00000154639
brinp3a.2
bone morphogenetic protein/retinoic acid inducible neural-specific 3a, tandem duplicate 2
chr5_+_36693859 0.17 ENSDART00000019259
dlb
deltaB
chr24_+_17140938 0.17 ENSDART00000149134
mllt10
MLLT10, histone lysine methyltransferase DOT1L cofactor
chr5_+_37379825 0.16 ENSDART00000171826
klhl13
kelch-like family member 13
chr2_+_33383227 0.15 ENSDART00000183068
slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr3_+_35406395 0.15 ENSDART00000055266
ENSDART00000150918
rbbp6
retinoblastoma binding protein 6
chr18_+_39327010 0.15 ENSDART00000012164
tmod2
tropomodulin 2
chr19_+_38167468 0.14 ENSDART00000160756
phf14
PHD finger protein 14
chr14_+_40852497 0.14 ENSDART00000128588
ENSDART00000166065
taf7
TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr14_-_30897177 0.13 ENSDART00000087918
slc7a3b
solute carrier family 7 (cationic amino acid transporter, y+ system), member 3b
chr23_-_6982966 0.13 ENSDART00000033774
ENSDART00000169965
edem2
ER degradation enhancer, mannosidase alpha-like 2
chr11_+_16152316 0.13 ENSDART00000081054
tada3l
transcriptional adaptor 3 (NGG1 homolog, yeast)-like
chr22_+_3238474 0.13 ENSDART00000157954
si:ch1073-178p5.3
si:ch1073-178p5.3
chr23_+_31979602 0.13 ENSDART00000140351
pan2
PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr1_-_17711361 0.12 ENSDART00000078848
ufsp2
ufm1-specific peptidase 2
chr3_+_47322494 0.11 ENSDART00000102202
ppap2d
phosphatidic acid phosphatase type 2D
chr5_-_41709234 0.11 ENSDART00000083656
atxn2
ataxin 2
chr11_+_2710530 0.10 ENSDART00000132768
ENSDART00000030921
ENSDART00000040147
mapk14b
mitogen-activated protein kinase 14b
chr12_+_15487834 0.10 ENSDART00000181138
arhgap23b
Rho GTPase activating protein 23b
chr3_-_52674089 0.10 ENSDART00000154260
ENSDART00000125455
si:dkey-210j14.4
si:dkey-210j14.4
chr17_-_51260476 0.10 ENSDART00000084348
trappc12
trafficking protein particle complex 12
chr20_-_4031475 0.10 ENSDART00000112053
fam89a
family with sequence similarity 89, member A
chr9_-_34121839 0.08 ENSDART00000000004
slc35a5
solute carrier family 35, member A5
chr4_+_9178913 0.08 ENSDART00000168558
nfyba
nuclear transcription factor Y, beta a
chr18_-_25645680 0.08 ENSDART00000135874
si:ch211-13k12.2
si:ch211-13k12.2
chr3_+_43774369 0.07 ENSDART00000157964
zc3h7a
zinc finger CCCH-type containing 7A
chr21_-_13751535 0.07 ENSDART00000111666
npdc1a
neural proliferation, differentiation and control, 1a
chr15_+_4988189 0.06 ENSDART00000142995
ENSDART00000062852
spcs2
signal peptidase complex subunit 2
chr20_+_19423823 0.06 ENSDART00000152216
znf513a
zinc finger protein 513a
chr14_-_31619408 0.06 ENSDART00000173277
mmgt1
membrane magnesium transporter 1
chr25_+_4787431 0.06 ENSDART00000170640
myo5c
myosin VC
chr24_-_9689915 0.05 ENSDART00000185972
ENSDART00000093046
uba5
ubiquitin-like modifier activating enzyme 5
chr24_+_17345521 0.04 ENSDART00000024722
ENSDART00000154250
ezh2
enhancer of zeste 2 polycomb repressive complex 2 subunit
chr7_+_11390462 0.04 ENSDART00000114383
tlnrd1
talin rod domain containing 1
chr12_+_17603528 0.04 ENSDART00000111565
pms2
PMS1 homolog 2, mismatch repair system component
chr14_-_46117345 0.04 ENSDART00000172166
NDUFC1
si:ch211-235e9.6
chr4_-_27129697 0.03 ENSDART00000131240
zbed4
zinc finger, BED-type containing 4
chr11_-_24532988 0.03 ENSDART00000067078
plekhg5a
pleckstrin homology domain containing, family G (with RhoGef domain) member 5a
chr19_+_32456974 0.03 ENSDART00000088265
atxn1a
ataxin 1a
chr16_-_45225520 0.03 ENSDART00000158855
fxyd1
FXYD domain containing ion transport regulator 1 (phospholemman)
chr14_+_21159693 0.03 ENSDART00000192678
zgc:136929
zgc:136929
chr6_+_46668717 0.02 ENSDART00000064853
oxtrl
oxytocin receptor like
chr14_-_26465729 0.02 ENSDART00000143454
syvn1
synovial apoptosis inhibitor 1, synoviolin
chr19_-_22568203 0.02 ENSDART00000182888
pleca
plectin a
chr19_-_17864213 0.02 ENSDART00000151043
ints8
integrator complex subunit 8
chr7_-_50395395 0.01 ENSDART00000065868
vps33b
vacuolar protein sorting 33B
chr17_+_12658411 0.01 ENSDART00000139918
gpn1
GPN-loop GTPase 1
chr11_+_3989403 0.00 ENSDART00000082379
spcs1
signal peptidase complex subunit 1

Network of associatons between targets according to the STRING database.

First level regulatory network of bhlha15_bhlhe23+si:ch211-196c10.13_bhlhe22

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0071361 cellular response to ethanol(GO:0071361)
0.4 1.5 GO:0060074 synapse maturation(GO:0060074)
0.2 0.5 GO:0021530 spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.1 2.4 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 0.4 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
0.1 1.6 GO:0016199 axon midline choice point recognition(GO:0016199)
0.1 0.3 GO:1900274 positive regulation of phospholipase C activity(GO:0010863) regulation of phospholipase C activity(GO:1900274)
0.1 2.2 GO:0051932 synaptic transmission, GABAergic(GO:0051932)
0.1 0.9 GO:1990118 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.4 GO:1901490 protein kinase D signaling(GO:0089700) regulation of lymphangiogenesis(GO:1901490)
0.1 0.4 GO:0014896 muscle hypertrophy(GO:0014896)
0.1 0.2 GO:0060945 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) Schwann cell migration(GO:0036135) cardiac neuron differentiation(GO:0060945) cardiac neuron development(GO:0060959)
0.1 0.3 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.1 0.5 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 0.7 GO:0006991 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 1.2 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 0.4 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.0 0.6 GO:0048669 collateral sprouting in absence of injury(GO:0048669) regulation of collateral sprouting in absence of injury(GO:0048696)
0.0 1.0 GO:1902807 negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.5 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.2 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.2 GO:0060080 inhibitory postsynaptic potential(GO:0060080) regulation of synaptic transmission, glycinergic(GO:0060092)
0.0 0.4 GO:0003139 secondary heart field specification(GO:0003139) regulation of organ growth(GO:0046620)
0.0 0.2 GO:0070650 actin filament bundle distribution(GO:0070650)
0.0 1.5 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 1.5 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.3 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.2 GO:0032986 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 0.7 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.1 GO:1902837 L-arginine import(GO:0043091) amino acid import across plasma membrane(GO:0089718) arginine import(GO:0090467) L-arginine import across plasma membrane(GO:0097638) L-arginine transport(GO:1902023) L-arginine import into cell(GO:1902765) amino acid import into cell(GO:1902837) L-arginine transmembrane transport(GO:1903400) arginine transmembrane transport(GO:1903826)
0.0 0.2 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.7 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.1 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.1 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.7 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.2 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.2 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.1 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 1.4 GO:0006979 response to oxidative stress(GO:0006979)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:0005955 calcineurin complex(GO:0005955)
0.2 2.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 4.9 GO:0034707 chloride channel complex(GO:0034707)
0.1 0.7 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 0.6 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 1.0 GO:0099634 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 0.5 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.2 GO:0071564 npBAF complex(GO:0071564)
0.0 1.1 GO:0055037 recycling endosome(GO:0055037)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.7 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.3 1.6 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.2 2.2 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237) benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.1 2.4 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 1.2 GO:0015386 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 1.2 GO:0033549 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) MAP kinase phosphatase activity(GO:0033549)
0.1 1.5 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.1 0.6 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.1 1.6 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.3 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.7 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.3 GO:0005163 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.0 0.2 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.1 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.2 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.4 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 1.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0015924 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 1.0 GO:0019902 phosphatase binding(GO:0019902)
0.0 0.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.4 GO:0019003 GDP binding(GO:0019003)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.0 PID IGF1 PATHWAY IGF1 pathway
0.0 0.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.7 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.3 PID SHP2 PATHWAY SHP2 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 7.0 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 1.6 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.6 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.2 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.2 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters