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PRJNA207719: Tissue specific transcriptome profiling
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Results for bcl11aa
Z-value: 0.77
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Transcription factors associated with bcl11aa
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| bcl11aa | dr11_v1_chr13_+_25846528_25846528 | 0.84 | 7.7e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr8_+_25173317 Show fit | 0.48 |
ENSDART00000142006
|
G protein-coupled receptor 61 |
|
| chr7_+_46368520 Show fit | 0.44 |
ENSDART00000192821
|
zinc finger protein 536 |
|
| chr2_+_21855291 Show fit | 0.40 |
ENSDART00000186204
|
carbonic anhydrase VIII |
|
| chr2_+_21855036 Show fit | 0.37 |
ENSDART00000140012
|
carbonic anhydrase VIII |
|
| chr3_+_28576173 Show fit | 0.36 |
ENSDART00000151189
|
septin 12 |
|
| chr19_+_30633453 Show fit | 0.34 |
ENSDART00000052124
|
family with sequence similarity 49, member A-like |
|
| chr20_-_20821783 Show fit | 0.32 |
ENSDART00000152577
ENSDART00000027603 ENSDART00000145601 |
creatine kinase, brain b |
|
| chr2_-_31302615 Show fit | 0.29 |
ENSDART00000034784
ENSDART00000060812 |
adenylate cyclase activating polypeptide 1b |
|
| chr19_+_29798064 Show fit | 0.29 |
ENSDART00000167803
ENSDART00000051804 |
MARCKS-like 1b |
|
| chr5_-_31926906 Show fit | 0.28 |
ENSDART00000187340
|
slingshot protein phosphatase 1b |
Network of associatons between targets according to the STRING database.
First level regulatory network of bcl11aa
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.8 | GO:0036269 | swimming behavior(GO:0036269) |
| 0.0 | 0.6 | GO:0070098 | chemokine-mediated signaling pathway(GO:0070098) |
| 0.0 | 0.5 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
| 0.0 | 0.3 | GO:0042396 | phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314) |
| 0.1 | 0.2 | GO:0045887 | regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887) |
| 0.0 | 0.1 | GO:1903385 | dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385) |
| 0.0 | 0.1 | GO:0036336 | dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336) |
| 0.0 | 0.1 | GO:0060829 | negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829) |
| 0.0 | 0.1 | GO:0000066 | mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575) |
| 0.0 | 0.1 | GO:2000392 | lamellipodium morphogenesis(GO:0072673) regulation of lamellipodium morphogenesis(GO:2000392) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.8 | GO:0031105 | septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156) |
| 0.0 | 0.2 | GO:0005797 | Golgi medial cisterna(GO:0005797) |
| 0.0 | 0.2 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
| 0.0 | 0.1 | GO:0098837 | postsynaptic recycling endosome(GO:0098837) |
| 0.0 | 0.1 | GO:0031931 | TORC1 complex(GO:0031931) |
| 0.0 | 0.1 | GO:0032433 | filopodium tip(GO:0032433) |
| 0.0 | 0.1 | GO:0070390 | transcription export complex 2(GO:0070390) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.8 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 0.1 | 0.3 | GO:0016521 | pituitary adenylate cyclase activating polypeptide activity(GO:0016521) |
| 0.0 | 0.3 | GO:0016775 | creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775) |
| 0.0 | 0.3 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
| 0.0 | 0.2 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.0 | 0.1 | GO:0016300 | tRNA (uracil) methyltransferase activity(GO:0016300) |
| 0.0 | 0.1 | GO:0051916 | granulocyte colony-stimulating factor binding(GO:0051916) |
| 0.0 | 0.1 | GO:0004679 | AMP-activated protein kinase activity(GO:0004679) |
| 0.0 | 0.1 | GO:0008142 | oxysterol binding(GO:0008142) |
| 0.0 | 0.1 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | PID EPHA2 FWD PATHWAY | EPHA2 forward signaling |
| 0.0 | 0.3 | PID INTEGRIN A9B1 PATHWAY | Alpha9 beta1 integrin signaling events |
| 0.0 | 0.2 | PID ARF6 DOWNSTREAM PATHWAY | Arf6 downstream pathway |
| 0.0 | 0.2 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
| 0.0 | 0.1 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 0.0 | 0.4 | REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.0 | 0.3 | REACTOME SIGNAL ATTENUATION | Genes involved in Signal attenuation |
| 0.0 | 0.2 | REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 | Genes involved in Regulation of AMPK activity via LKB1 |
| 0.0 | 0.2 | REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS | Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis |
| 0.0 | 0.1 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.0 | 0.1 | REACTOME DSCAM INTERACTIONS | Genes involved in DSCAM interactions |
| 0.0 | 0.1 | REACTOME MTORC1 MEDIATED SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 0.0 | 0.1 | REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |