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PRJNA207719: Tissue specific transcriptome profiling
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Results for barx2
Z-value: 1.11
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Transcription factors associated with barx2
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| barx2 | dr11_v1_chr18_+_47313715_47313715 | -0.12 | 8.5e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr4_+_9669717 Show fit | 1.83 |
ENSDART00000004604
|
si:dkey-153k10.9 |
|
| chr9_-_9348058 Show fit | 0.93 |
ENSDART00000132257
|
zgc:113337 |
|
| chr11_+_30057762 Show fit | 0.92 |
ENSDART00000164139
|
Nance-Horan syndrome b (congenital cataracts and dental anomalies) |
|
| chr19_-_26869103 Show fit | 0.91 |
ENSDART00000089699
|
proline-rich transmembrane protein 1 |
|
| chr12_+_18578597 Show fit | 0.87 |
ENSDART00000134944
|
glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein, b |
|
| chr23_+_40460333 Show fit | 0.86 |
ENSDART00000184658
|
SOGA family member 3b |
|
| chr16_+_5774977 Show fit | 0.86 |
ENSDART00000134202
|
cholecystokinin a |
|
| chr5_+_63668735 Show fit | 0.82 |
ENSDART00000134261
ENSDART00000097330 |
dynamin 1b |
|
| chr22_-_13851297 Show fit | 0.76 |
ENSDART00000080306
|
S100 calcium binding protein, beta (neural) |
|
| chr9_+_7998794 Show fit | 0.75 |
ENSDART00000138167
|
myosin XVI |
Network of associatons between targets according to the STRING database.
First level regulatory network of barx2
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.3 | GO:0035336 | long-chain fatty-acyl-CoA metabolic process(GO:0035336) |
| 0.2 | 1.2 | GO:0046952 | ketone body catabolic process(GO:0046952) |
| 0.0 | 0.9 | GO:0007586 | digestion(GO:0007586) |
| 0.1 | 0.8 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
| 0.0 | 0.8 | GO:0098884 | postsynaptic neurotransmitter receptor internalization(GO:0098884) |
| 0.0 | 0.8 | GO:0014059 | dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059) |
| 0.0 | 0.8 | GO:0030050 | vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515) |
| 0.2 | 0.7 | GO:0034154 | toll-like receptor 7 signaling pathway(GO:0034154) |
| 0.1 | 0.6 | GO:0000012 | single strand break repair(GO:0000012) |
| 0.0 | 0.6 | GO:0098962 | regulation of postsynaptic neurotransmitter receptor activity(GO:0098962) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.3 | GO:0043025 | neuronal cell body(GO:0043025) |
| 0.0 | 0.9 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.0 | 0.8 | GO:0098844 | postsynaptic endocytic zone membrane(GO:0098844) |
| 0.0 | 0.8 | GO:0098978 | glutamatergic synapse(GO:0098978) |
| 0.0 | 0.8 | GO:0030141 | secretory granule(GO:0030141) |
| 0.0 | 0.7 | GO:0043209 | myelin sheath(GO:0043209) |
| 0.0 | 0.7 | GO:0031903 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
| 0.0 | 0.5 | GO:0016605 | PML body(GO:0016605) |
| 0.1 | 0.4 | GO:0035060 | brahma complex(GO:0035060) |
| 0.0 | 0.4 | GO:0045171 | intercellular bridge(GO:0045171) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.2 | GO:0008260 | 3-oxoacid CoA-transferase activity(GO:0008260) |
| 0.0 | 0.9 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.2 | 0.8 | GO:0044548 | S100 protein binding(GO:0044548) |
| 0.0 | 0.8 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.0 | 0.8 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 0.0 | 0.8 | GO:0003727 | single-stranded RNA binding(GO:0003727) |
| 0.1 | 0.7 | GO:0080019 | fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019) |
| 0.0 | 0.7 | GO:0033549 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) MAP kinase phosphatase activity(GO:0033549) |
| 0.0 | 0.7 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
| 0.0 | 0.7 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.0 | PID E2F PATHWAY | E2F transcription factor network |
| 0.0 | 0.5 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.0 | 0.3 | PID THROMBIN PAR4 PATHWAY | PAR4-mediated thrombin signaling events |
| 0.0 | 0.3 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 0.0 | 0.2 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.0 | 0.2 | PID ARF6 PATHWAY | Arf6 signaling events |
| 0.0 | 0.1 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.8 | REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
| 0.1 | 0.7 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING | Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling |
| 0.0 | 0.7 | REACTOME PEROXISOMAL LIPID METABOLISM | Genes involved in Peroxisomal lipid metabolism |
| 0.0 | 0.5 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.0 | 0.4 | REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway |
| 0.0 | 0.4 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.0 | 0.3 | REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
| 0.0 | 0.3 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.0 | 0.3 | REACTOME N GLYCAN ANTENNAE ELONGATION | Genes involved in N-Glycan antennae elongation |
| 0.0 | 0.2 | REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |