ISMARA results: barx1

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PRJNA207719: Tissue specific transcriptome profiling

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Results for barx1

Z-value: 1.32

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Transcription factors associated with barx1

Gene Symbol	Gene ID	Gene Info
barx1 NCBI UniProt	ENSDARG00000007407	BARX homeobox 1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
barx1	dr11_v1_chr11_+_27543093_27543093	0.16	8.0e-01	Click!

Activity profile of barx1 motif

Sorted Z-values of barx1 motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr25_+_35019693 Show fit	0.88	ENSDART00000046218	flnca NCBI UniProt Show fit	filamin C, gamma a (actin binding protein 280)
chr25_+_31276842 Show fit	0.87	ENSDART00000187238	tnni2a.4 NCBI UniProt Show fit	troponin I type 2a (skeletal, fast), tandem duplicate 4
chr8_-_18537866 Show fit	0.76	ENSDART00000148802 ENSDART00000148962 ENSDART00000149506	nexn NCBI UniProt Show fit	nexilin (F actin binding protein)
chr11_-_17981421 Show fit	0.74	ENSDART00000005999 ENSDART00000104046	twf2b NCBI UniProt Show fit	twinfilin actin-binding protein 2b
chr22_-_31060579 Show fit	0.73	ENSDART00000182376	cand2 NCBI UniProt Show fit	cullin-associated and neddylation-dissociated 2 (putative)
chr5_+_2815021 Show fit	0.72	ENSDART00000020472	hpda NCBI UniProt Show fit	4-hydroxyphenylpyruvate dioxygenase a
chr23_+_409578 Show fit	0.68	ENSDART00000008177	slc25a55b NCBI UniProt Show fit	solute carrier family 25, member 55b
chr3_+_59851537 Show fit	0.66	ENSDART00000180997	CU693479.1 NCBI UniProt Show fit
chr14_-_970853 Show fit	0.65	ENSDART00000130801	acsl1b NCBI UniProt Show fit	acyl-CoA synthetase long chain family member 1b
chr14_+_15622817 Show fit	0.62	ENSDART00000158624	si:dkey-203a12.9 NCBI UniProt Show fit	si:dkey-203a12.9

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of barx1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.2	GO:0003009	skeletal muscle contraction(GO:0003009)
0.0	1.1	GO:0070098	chemokine-mediated signaling pathway(GO:0070098)
0.0	1.0	GO:0048747	muscle fiber development(GO:0048747)
0.1	0.9	GO:0046716	muscle cell cellular homeostasis(GO:0046716)
0.2	0.8	GO:0048739	cardiac muscle fiber development(GO:0048739)
0.0	0.8	GO:0032231	regulation of actin filament bundle assembly(GO:0032231)
0.2	0.7	GO:0010265	SCF complex assembly(GO:0010265)
0.1	0.7	GO:0010591	regulation of lamellipodium assembly(GO:0010591)
0.1	0.7	GO:0006572	tyrosine catabolic process(GO:0006572)
0.1	0.7	GO:0015810	acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)

Showing 1 to 10 of 169 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	3.6	GO:0030018	Z disc(GO:0030018)
0.0	2.5	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	1.6	GO:0005861	troponin complex(GO:0005861)
0.0	1.5	GO:0005884	actin filament(GO:0005884)
0.0	0.9	GO:0022626	cytosolic ribosome(GO:0022626) cytosolic small ribosomal subunit(GO:0022627)
0.0	0.6	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.0	0.6	GO:0005747	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1	0.5	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.1	0.5	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.5	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)

Showing 1 to 10 of 55 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	3.7	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	1.2	GO:0008009	chemokine activity(GO:0008009)
0.0	1.0	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.9	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.0	0.9	GO:0042805	actinin binding(GO:0042805)
0.2	0.7	GO:0003868	4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
0.1	0.7	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.7	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.7	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.7	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)

Showing 1 to 10 of 109 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.9	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	0.8	PID FANCONI PATHWAY	Fanconi anemia pathway
0.0	0.6	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.1	0.5	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.5	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.3	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.3	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	0.2	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	0.2	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.2	PID IL12 2PATHWAY	IL12-mediated signaling events

Showing 1 to 10 of 16 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	3.5	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.1	0.8	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.7	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.7	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1	0.6	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.6	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.6	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.1	0.5	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.5	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.5	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex

Showing 1 to 10 of 37 entries

Results for barx1

Z-value: 1.32

Motif logo

Transcription factors associated with barx1

Activity-expression correlation:

Activity profile of barx1 motif

Sorted Z-values of barx1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of barx1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: