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PRJNA207719: Tissue specific transcriptome profiling
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Results for barhl2
Z-value: 0.77
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Transcription factors associated with barhl2
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| barhl2 | dr11_v1_chr6_+_24817852_24817852 | -0.88 | 4.8e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr1_-_52437056 Show fit | 0.54 |
ENSDART00000138337
|
si:ch211-217k17.12 |
|
| chr12_+_20352400 Show fit | 0.43 |
ENSDART00000066383
|
hemoglobin, alpha embryonic 5 |
|
| chr24_-_4765740 Show fit | 0.40 |
ENSDART00000121576
|
carboxypeptidase B1 (tissue) |
|
| chr15_+_34699585 Show fit | 0.40 |
ENSDART00000017569
|
tumor necrosis factor b (TNF superfamily, member 2) |
|
| chr4_+_73606482 Show fit | 0.36 |
ENSDART00000150765
|
si:ch211-165i18.2 |
|
| chr21_+_25777425 Show fit | 0.35 |
ENSDART00000021620
|
claudin d |
|
| chr15_-_2640966 Show fit | 0.35 |
ENSDART00000063320
|
claudin e |
|
| chr1_+_40802454 Show fit | 0.34 |
ENSDART00000193568
|
carboxypeptidase Z |
|
| chr1_-_19845378 Show fit | 0.34 |
ENSDART00000139314
ENSDART00000132958 ENSDART00000147502 |
glyoxylate reductase/hydroxypyruvate reductase b |
|
| chr7_+_13988075 Show fit | 0.34 |
ENSDART00000186812
|
furin (paired basic amino acid cleaving enzyme) a |
Network of associatons between targets according to the STRING database.
First level regulatory network of barhl2
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.8 | GO:0042743 | hydrogen peroxide metabolic process(GO:0042743) |
| 0.1 | 0.6 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.0 | 0.6 | GO:0070098 | chemokine-mediated signaling pathway(GO:0070098) |
| 0.0 | 0.5 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
| 0.0 | 0.5 | GO:0030183 | B cell differentiation(GO:0030183) |
| 0.0 | 0.5 | GO:0042541 | hemoglobin biosynthetic process(GO:0042541) |
| 0.0 | 0.4 | GO:0006749 | glutathione metabolic process(GO:0006749) |
| 0.1 | 0.3 | GO:2000009 | regulation of protein localization to cell surface(GO:2000008) negative regulation of protein localization to cell surface(GO:2000009) |
| 0.1 | 0.3 | GO:1990403 | embryonic brain development(GO:1990403) |
| 0.1 | 0.3 | GO:0051000 | regulation of nitric-oxide synthase activity(GO:0050999) positive regulation of nitric-oxide synthase activity(GO:0051000) beta-amyloid clearance(GO:0097242) regulation of beta-amyloid clearance(GO:1900221) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.0 | GO:0022626 | cytosolic large ribosomal subunit(GO:0022625) cytosolic ribosome(GO:0022626) |
| 0.0 | 0.8 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.0 | 0.4 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.0 | 0.4 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
| 0.1 | 0.3 | GO:0019815 | B cell receptor complex(GO:0019815) |
| 0.1 | 0.3 | GO:0034363 | intermediate-density lipoprotein particle(GO:0034363) |
| 0.1 | 0.3 | GO:0005854 | nascent polypeptide-associated complex(GO:0005854) |
| 0.0 | 0.3 | GO:0097651 | phosphatidylinositol 3-kinase complex, class IB(GO:0005944) phosphatidylinositol 3-kinase complex, class I(GO:0097651) |
| 0.0 | 0.3 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.0 | 0.3 | GO:0048188 | Set1C/COMPASS complex(GO:0048188) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.9 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.0 | 0.6 | GO:0019957 | C-C chemokine binding(GO:0019957) |
| 0.0 | 0.5 | GO:0045182 | translation regulator activity(GO:0045182) |
| 0.0 | 0.4 | GO:0030250 | calcium sensitive guanylate cyclase activator activity(GO:0008048) cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250) |
| 0.0 | 0.4 | GO:0031720 | haptoglobin binding(GO:0031720) |
| 0.0 | 0.4 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.0 | 0.4 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.1 | 0.3 | GO:0016618 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
| 0.1 | 0.3 | GO:0052905 | tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905) |
| 0.0 | 0.3 | GO:0003987 | acetate-CoA ligase activity(GO:0003987) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.3 | ST JAK STAT PATHWAY | Jak-STAT Pathway |
| 0.0 | 0.3 | PID CONE PATHWAY | Visual signal transduction: Cones |
| 0.0 | 0.3 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.0 | 0.2 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.0 | 0.2 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.0 | 0.2 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.0 | 0.1 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.0 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
| 0.0 | 0.8 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.1 | 0.3 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
| 0.0 | 0.3 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.0 | 0.3 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
| 0.0 | 0.3 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.0 | 0.2 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |
| 0.0 | 0.2 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.0 | 0.1 | REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Acetylcholine Neurotransmitter Release Cycle |
| 0.0 | 0.1 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |