PRJNA207719: Tissue specific transcriptome profiling


Results for atf5a+atf5b

Z-value: 1.67

Motif logo

Transcription factors associated with atf5a+atf5b

Gene Symbol Gene ID Gene Info
ENSDARG00000068096 activating transcription factor 5a
ENSDARG00000077785 activating transcription factor 5b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot

Activity profile of atf5a+atf5b motif

Sorted Z-values of atf5a+atf5b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr23_-_26521970 1.88 ENSDART00000143712
chr19_-_21832441 1.67 ENSDART00000151272
myelin basic protein a
chr9_+_38962017 1.53 ENSDART00000140436
microtubule-associated protein 2
chr21_-_22115136 1.37 ENSDART00000134715
ELMO/CED-12 domain containing 1
chr3_-_16227490 1.37 ENSDART00000057159
calcium channel, voltage-dependent, beta 1 subunit
chr9_+_31282161 1.24 ENSDART00000010774
zic family member 2 (odd-paired homolog, Drosophila), a
chr16_+_29303971 1.22 ENSDART00000087149
hyaluronan and proteoglycan link protein 2
chr9_-_27648683 1.21 ENSDART00000017292
syntaxin binding protein 5-like
chr7_-_28147838 1.19 ENSDART00000158921
LIM domain only 1
chr3_-_16227683 1.16 ENSDART00000111707
calcium channel, voltage-dependent, beta 1 subunit
chr18_+_17786548 1.14 ENSDART00000189493
chr21_+_13908858 1.13 ENSDART00000148199
syntaxin binding protein 1a
chr24_+_34606966 1.10 ENSDART00000105477
leucine rich repeat transmembrane neuronal 2
chr7_+_26138240 1.09 ENSDART00000193750
N-acetyltransferase 16
chr18_+_22793465 1.08 ENSDART00000149685
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, a
chr1_-_5746030 1.07 ENSDART00000150863
neuropilin 2a
chr3_+_29714775 1.06 ENSDART00000041388
calcium channel, voltage-dependent, gamma subunit 2a
chr19_+_30662529 1.06 ENSDART00000175662
family with sequence similarity 49, member A-like
chr5_+_25952340 1.05 ENSDART00000147188
transient receptor potential cation channel, subfamily M, member 3
chr13_-_35051897 1.03 ENSDART00000129559
BTB (POZ) domain containing 3b
chr9_-_35069645 1.00 ENSDART00000122679
amyloid beta (A4) precursor protein b
chr17_-_20711735 0.98 ENSDART00000150056
ankyrin 3b
chr6_-_52400896 0.96 ENSDART00000187624
matrix metallopeptidase 24
chr3_-_30123113 0.94 ENSDART00000153562
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr16_-_24518027 0.93 ENSDART00000134120
cell adhesion molecule 4
chr17_-_37214196 0.91 ENSDART00000128715
kinesin family member 3Cb
chr24_-_1341543 0.91 ENSDART00000169341
neuropilin 1a
chr13_-_33007781 0.90 ENSDART00000183671
RNA binding motif protein 25a
chr21_+_13353263 0.86 ENSDART00000114677
chr13_-_21739142 0.86 ENSDART00000078460
chr18_+_7283283 0.85 ENSDART00000141493
chr3_-_46818001 0.83 ENSDART00000166505
ELAV like neuron-specific RNA binding protein 3
chr18_+_22793743 0.83 ENSDART00000150106
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, a
chr3_-_46817838 0.83 ENSDART00000028610
ELAV like neuron-specific RNA binding protein 3
chr18_-_23875370 0.77 ENSDART00000130163
nuclear receptor subfamily 2, group F, member 2
chr14_+_14225048 0.77 ENSDART00000168749
neuroligin 3a
chr18_-_38088099 0.77 ENSDART00000146120
leucine zipper protein 2
chr10_-_43568239 0.77 ENSDART00000131731
myocyte enhancer factor 2ca
chr7_+_25323742 0.76 ENSDART00000110347
cytochrome P450, family 26, subfamily b, polypeptide 1
chr5_-_64213253 0.76 ENSDART00000171711
G protein signaling modulator 1a
chr13_-_23007813 0.74 ENSDART00000057638
hexokinase 1
chr18_-_38087875 0.74 ENSDART00000111301
leucine zipper protein 2
chr15_+_22267847 0.73 ENSDART00000110665
sperm autoantigenic protein 17
chr14_+_14224730 0.73 ENSDART00000180112
neuroligin 3a
chr19_-_3931917 0.72 ENSDART00000162532
MAP7 domain containing 1b
chr2_-_34555945 0.69 ENSDART00000056671
bone morphogenetic protein/retinoic acid inducible neural-specific 2
chr20_-_23026223 0.68 ENSDART00000015755
RAS-like, family 11, member B
chr12_+_8373525 0.68 ENSDART00000152180
AT-rich interaction domain 5B
chr18_-_29977431 0.68 ENSDART00000135357
chr16_-_9802998 0.66 ENSDART00000154217
TAP binding protein (tapasin)-like
chr3_-_26341959 0.66 ENSDART00000169344
chr23_-_35069805 0.64 ENSDART00000087219

chr3_+_15358459 0.62 ENSDART00000141808
SH2B adaptor protein 1
chr5_+_58492699 0.62 ENSDART00000181584

chr5_-_33215261 0.61 ENSDART00000097935
chr1_+_32521469 0.60 ENSDART00000113818
neuroligin 4a
chr3_+_22905341 0.60 ENSDART00000111435
histone deacetylase 5
chr17_-_37054959 0.59 ENSDART00000151921
DNA (cytosine-5-)-methyltransferase 3 alpha b
chr24_+_9372292 0.59 ENSDART00000082422
chr16_-_44649053 0.59 ENSDART00000184807

chr16_+_10346277 0.57 ENSDART00000081092
chr22_-_30935510 0.57 ENSDART00000133335
chr21_-_17482465 0.56 ENSDART00000004548
BarH-like homeobox 1b
chr9_+_25775816 0.55 ENSDART00000127834
zinc finger E-box binding homeobox 2a
chr5_-_48307804 0.55 ENSDART00000182831
myocyte enhancer factor 2cb
chr16_-_13004166 0.54 ENSDART00000133735
calcium channel, voltage-dependent, gamma subunit 7b
chr5_-_67911111 0.53 ENSDART00000051833
GS homeobox 1
chr3_+_15358625 0.53 ENSDART00000143280
SH2B adaptor protein 1
chr7_+_20019125 0.53 ENSDART00000186391
B-cell CLL/lymphoma 6, member B
chr13_+_28854438 0.53 ENSDART00000193407

chr17_-_20849879 0.52 ENSDART00000088100
ankyrin 3b
chr18_+_28988373 0.52 ENSDART00000018685
synaptotagmin IXa
chr18_-_23875219 0.50 ENSDART00000059976
nuclear receptor subfamily 2, group F, member 2
chr5_-_28679135 0.49 ENSDART00000193585
tenascin C
chr17_-_37052622 0.49 ENSDART00000186408
DNA (cytosine-5-)-methyltransferase 3 alpha b
chr14_-_44841335 0.49 ENSDART00000173011
chr11_-_22916641 0.48 ENSDART00000080201
MDM4, p53 regulator
chr3_-_37476278 0.47 ENSDART00000083442
chr15_+_36977208 0.47 ENSDART00000183625
kirre like nephrin family adhesion molecule 3, like
chr5_+_42467867 0.47 ENSDART00000172028
Pim proto-oncogene, serine/threonine kinase, related 58
chr23_-_27607039 0.46 ENSDART00000183639
PHD finger protein 8
chr5_+_22791686 0.46 ENSDART00000014806
neuronal PAS domain protein 2
chr11_-_44030962 0.46 ENSDART00000171910

chr16_-_29146624 0.46 ENSDART00000159814
myocyte enhancer factor 2d
chr16_+_39159752 0.46 ENSDART00000122081
syntabulin (syntaxin-interacting)
chr20_+_23676649 0.44 ENSDART00000035239
NIMA-related kinase 1
chr14_-_44841503 0.43 ENSDART00000179114
chr24_-_11309477 0.42 ENSDART00000137257
myosin VIIA and Rab interacting protein
chr20_-_26421112 0.42 ENSDART00000183767
A kinase (PRKA) anchor protein 12b
chr16_-_34338537 0.42 ENSDART00000142223
human immunodeficiency virus type I enhancer binding protein 3b
chr23_-_27692717 0.41 ENSDART00000053878
chr18_+_22174630 0.41 ENSDART00000089549
RHO family interacting cell polarization regulator 1
chr18_-_50152689 0.40 ENSDART00000006078
lysyl oxidase-like 1
chr16_+_25259313 0.40 ENSDART00000058938
F-box protein 32
chr20_-_26420939 0.39 ENSDART00000110883
A kinase (PRKA) anchor protein 12b
chr17_+_42027969 0.39 ENSDART00000147563
kizuna centrosomal protein
chr5_-_40178092 0.38 ENSDART00000146664
WD repeat and FYVE domain containing 3
chr4_-_8902406 0.38 ENSDART00000192962
metallophosphoesterase domain containing 1
chr17_+_25432449 0.38 ENSDART00000150195
serine/arginine repetitive matrix 1
chr18_+_34362608 0.37 ENSDART00000131478
potassium voltage-gated channel, shaker-related subfamily, beta member 1 a
chr12_+_27024676 0.36 ENSDART00000153104
male-specific lethal 1 homolog b (Drosophila)
chr21_+_33249478 0.36 ENSDART00000169972
chr1_+_16573982 0.35 ENSDART00000166317
microtubule associated tumor suppressor 1b
chr1_+_52130213 0.35 ENSDART00000018817
ring finger protein 11a
chr6_+_36807861 0.34 ENSDART00000161708
chr22_+_3045495 0.34 ENSDART00000164061

chr16_-_24135508 0.34 ENSDART00000171819
basal cell adhesion molecule (Lutheran blood group)
chr14_+_8127893 0.33 ENSDART00000169091
pleckstrin and Sec7 domain containing 2
chr6_-_34008827 0.33 ENSDART00000191183
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr19_-_10214264 0.33 ENSDART00000053300
zinc finger protein 865
chr9_-_41401564 0.33 ENSDART00000059628
NGFI-A binding protein 1b (EGR1 binding protein 1)
chr13_+_23214100 0.32 ENSDART00000163393
sorbin and SH3 domain containing 1
chr5_+_45140914 0.32 ENSDART00000172702
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr1_+_41498697 0.31 ENSDART00000114230
deltex 4, E3 ubiquitin ligase
chr17_+_38262408 0.30 ENSDART00000017493
NK2 homeobox 1
chr21_-_26691959 0.30 ENSDART00000149702
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr17_-_29902187 0.29 ENSDART00000009104
estrogen-related receptor beta
chr18_+_17786710 0.29 ENSDART00000190203
chr21_-_38031038 0.29 ENSDART00000179483
RNA binding motif protein 41
chr4_+_5180650 0.28 ENSDART00000067390
fibroblast growth factor 6b
chr1_-_5745420 0.28 ENSDART00000166779
neuropilin 2a
chr12_-_3778848 0.28 ENSDART00000152128
chr10_+_29199172 0.28 ENSDART00000148828
phosphatidylinositol binding clathrin assembly protein a
chr7_-_20758825 0.27 ENSDART00000156717
chromodomain helicase DNA binding protein 3
chr1_+_41498188 0.27 ENSDART00000191934
deltex 4, E3 ubiquitin ligase
chr14_-_24110251 0.26 ENSDART00000079226
cytoplasmic polyadenylation element binding protein 4a
chr5_-_19052184 0.24 ENSDART00000133330
family with sequence similarity 214, member B
chr9_-_21230999 0.23 ENSDART00000150160
phospholipase A1 member A
chr2_+_30916188 0.23 ENSDART00000137012
myomesin 1a (skelemin)
chr12_-_31995840 0.23 ENSDART00000112881
glutamate receptor, ionotropic, N-methyl D-aspartate 2Cb
chr22_+_30089054 0.23 ENSDART00000185369
adducin 3 (gamma) a
chr14_-_24110062 0.22 ENSDART00000177062
cytoplasmic polyadenylation element binding protein 4a
chr25_-_16832705 0.22 ENSDART00000171336
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
chr11_+_26476153 0.22 ENSDART00000103507
un-named sa1614
chr11_-_25324534 0.22 ENSDART00000158598
chr10_-_43718914 0.22 ENSDART00000189277
centrin 3
chr17_+_38476300 0.22 ENSDART00000123298
StAR-related lipid transfer (START) domain containing 9
chr14_-_24110707 0.22 ENSDART00000133522
cytoplasmic polyadenylation element binding protein 4a
chr3_-_26787430 0.21 ENSDART00000087047
RAB40c, member RAS oncogene family
chr14_-_2209742 0.20 ENSDART00000054889
protocadherin 2 alpha b 5
chr23_-_18707418 0.20 ENSDART00000144668
chr17_-_7028418 0.20 ENSDART00000188305
SAM and SH3 domain containing 1b
chr4_-_64284924 0.20 ENSDART00000166733

chr11_-_37880492 0.19 ENSDART00000102868
ethanolamine kinase 2
chr9_+_6587364 0.19 ENSDART00000122279
four and a half LIM domains 2a
chr5_+_37785152 0.19 ENSDART00000053511
myosin Ic, paralog a
chr3_-_53533128 0.18 ENSDART00000183591
notch 3
chr1_-_40123943 0.18 ENSDART00000146917
chr13_-_13754091 0.18 ENSDART00000131255
kyphoscoliosis peptidase
chr24_+_10310577 0.18 ENSDART00000141718
OTU deubiquitinase with linear linkage specificity a
chr18_+_22217489 0.17 ENSDART00000165464
RHO family interacting cell polarization regulator 1
chr11_+_24046179 0.17 ENSDART00000006703
MAF1 homolog, negative regulator of RNA polymerase III
chr7_+_31879649 0.17 ENSDART00000099789
myosin binding protein C, cardiac
chr3_+_45758760 0.17 ENSDART00000076007
G protein-coupled estrogen receptor 1
chr6_-_42971184 0.16 ENSDART00000014552
ADP-ribosylation factor-like 8Ba
chr8_+_17884569 0.16 ENSDART00000134660
solute carrier family 44, member 5b
chr7_-_33881275 0.16 ENSDART00000100102
relaxin/insulin-like family peptide receptor 3.3a1
chr14_-_26425416 0.16 ENSDART00000088690
lectin, mannose-binding 2
chr20_-_31427390 0.16 ENSDART00000007735
chr8_-_40251126 0.15 ENSDART00000180435
lysine (K)-specific demethylase 2Ba
chr11_+_16152316 0.15 ENSDART00000081054
transcriptional adaptor 3 (NGG1 homolog, yeast)-like
chr9_+_30720048 0.15 ENSDART00000146115
Kruppel-like factor 12b
chr23_-_31506854 0.14 ENSDART00000131352
EYA transcriptional coactivator and phosphatase 4
chr4_-_13255700 0.14 ENSDART00000162277
glutamate receptor interacting protein 1
chr12_-_43435254 0.13 ENSDART00000182723
protein tyrosine phosphatase, receptor type, E, a
chr3_+_53156813 0.13 ENSDART00000114343
bromodomain containing 4
chr10_-_7386475 0.13 ENSDART00000167963
neuregulin 1
chr6_-_39765546 0.12 ENSDART00000185767
phosphofructokinase, muscle b
chr12_+_25945560 0.12 ENSDART00000109799
multimerin 2b
chr24_+_25919809 0.12 ENSDART00000006615
mitogen-activated protein kinase kinase kinase 15
chr3_+_15776446 0.12 ENSDART00000146651
zinc finger protein 652
chr1_+_23784905 0.12 ENSDART00000171951
slit homolog 2 (Drosophila)
chr3_+_17456428 0.11 ENSDART00000090676
chr10_-_34889053 0.11 ENSDART00000136966
coiled-coil domain containing 169
chr13_+_30874153 0.11 ENSDART00000112380
excision repair cross-complementation group 6
chr19_-_35596207 0.11 ENSDART00000136811
collagen, type VIII, alpha 2
chr23_+_42346799 0.10 ENSDART00000159985
cytochrome P450, family 2, subfamily AA, polypeptide 11
chr14_+_5385855 0.10 ENSDART00000031508
ladybird homeobox 2
chr10_+_8534750 0.10 ENSDART00000183960
TBC1 domain family, member 10Ab
chr13_+_11829072 0.10 ENSDART00000079356
suppressor of fused homolog (Drosophila)
chr20_+_54336137 0.09 ENSDART00000113792
CLOCK-interacting pacemaker b
chr18_+_5213338 0.08 ENSDART00000033574
solute carrier family 24 (sodium/potassium/calcium exchanger), member 5
chr4_-_72609735 0.08 ENSDART00000174299
chr9_-_19699728 0.08 ENSDART00000166780
chr8_-_14067517 0.07 ENSDART00000140948
death effector domain containing
chr3_-_50118140 0.07 ENSDART00000131913
hepatocyte growth factor-regulated tyrosine kinase substrate
chr20_+_15982482 0.07 ENSDART00000020999
angiopoietin-like 1a
chr7_-_38687431 0.07 ENSDART00000074490
apelin receptor 2
chr14_-_10387377 0.07 ENSDART00000145118
COMM domain containing 5
chr3_+_23703704 0.07 ENSDART00000024256
homeobox B6a
chr1_+_54835131 0.05 ENSDART00000145070
chr4_-_12104421 0.05 ENSDART00000139561
mitochondrial ribosomal protein S33
chr25_+_20694177 0.04 ENSDART00000073648
KxDL motif containing 1
chr15_-_23475051 0.04 ENSDART00000152460
NLR family member X1
chr8_+_18010568 0.04 ENSDART00000121984
single stranded DNA binding protein 3b
chr15_-_4023182 0.04 ENSDART00000190195

chr23_-_25779995 0.04 ENSDART00000110670
chr15_-_8763106 0.03 ENSDART00000154171
Rho GTPase activating protein 35a
chr1_+_16574312 0.03 ENSDART00000187067
microtubule associated tumor suppressor 1b
chr24_-_17400143 0.03 ENSDART00000134947
cullin 1b

Network of associatons between targets according to the STRING database.

First level regulatory network of atf5a+atf5b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0060845 lymphatic endothelial cell fate commitment(GO:0060838) venous endothelial cell differentiation(GO:0060843) venous endothelial cell fate commitment(GO:0060845)
0.3 0.8 GO:1904969 bleb assembly(GO:0032060) slow muscle cell migration(GO:1904969)
0.3 0.8 GO:0036076 ligamentous ossification(GO:0036076)
0.3 0.8 GO:0035992 tendon formation(GO:0035992)
0.2 1.2 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.2 0.9 GO:0060055 larval development(GO:0002164) larval heart development(GO:0007508) angiogenesis involved in wound healing(GO:0060055)
0.2 1.1 GO:0050951 detection of temperature stimulus(GO:0016048) sensory perception of temperature stimulus(GO:0050951)
0.2 0.5 GO:0014814 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887)
0.2 0.9 GO:0003232 bulbus arteriosus development(GO:0003232)
0.2 0.5 GO:0061187 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.1 1.5 GO:0097105 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.1 0.5 GO:0060074 synapse maturation(GO:0060074)
0.1 0.7 GO:0002931 response to ischemia(GO:0002931)
0.1 1.6 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.1 0.4 GO:1902260 negative regulation of potassium ion transmembrane transporter activity(GO:1901017) negative regulation of potassium ion transmembrane transport(GO:1901380) negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.1 0.5 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.1 0.7 GO:0060612 adipose tissue development(GO:0060612)
0.1 1.9 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.1 0.7 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 2.5 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.1 0.2 GO:0035019 somatic stem cell population maintenance(GO:0035019) symmetric cell division(GO:0098725)
0.1 0.7 GO:0019883 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 1.4 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
0.1 0.7 GO:0001678 cellular glucose homeostasis(GO:0001678)
0.1 0.2 GO:1903430 negative regulation of cell maturation(GO:1903430)
0.1 0.3 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.3 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.5 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.4 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.5 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.3 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.1 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.0 0.1 GO:0036135 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) Schwann cell migration(GO:0036135) cardiac neuron differentiation(GO:0060945) cardiac neuron development(GO:0060959)
0.0 0.1 GO:0007414 axonal defasciculation(GO:0007414)
0.0 0.4 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.2 GO:0003210 cardiac atrium formation(GO:0003210)
0.0 1.1 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.5 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 1.2 GO:0050708 regulation of protein secretion(GO:0050708)
0.0 0.2 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 1.0 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 1.1 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.7 GO:0048382 mesendoderm development(GO:0048382)
0.0 0.1 GO:0042308 regulation of protein import into nucleus(GO:0042306) negative regulation of protein import into nucleus(GO:0042308) negative regulation of nucleocytoplasmic transport(GO:0046823) negative regulation of protein localization to nucleus(GO:1900181) regulation of protein import(GO:1904589) negative regulation of protein import(GO:1904590)
0.0 0.1 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.0 1.0 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 0.1 GO:1904105 positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.0 0.5 GO:0039022 pronephric duct development(GO:0039022)
0.0 1.5 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.6 GO:0072114 pronephros morphogenesis(GO:0072114)
0.0 0.2 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.0 0.5 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.2 GO:0016074 snoRNA metabolic process(GO:0016074)
0.0 0.1 GO:2001240 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.1 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.0 0.5 GO:0009648 photoperiodism(GO:0009648)
0.0 0.9 GO:0008593 regulation of Notch signaling pathway(GO:0008593)
0.0 0.1 GO:0099639 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.0 0.1 GO:0061615 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.7 GO:0003341 cilium movement(GO:0003341)
0.0 2.6 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 1.6 GO:0008654 phospholipid biosynthetic process(GO:0008654)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 GO:0043209 myelin sheath(GO:0043209)
0.1 0.5 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.1 0.6 GO:0016586 RSC complex(GO:0016586)
0.0 3.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.2 GO:0060171 stereocilium membrane(GO:0060171)
0.0 0.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.4 GO:0072487 MSL complex(GO:0072487)
0.0 0.5 GO:0031045 dense core granule(GO:0031045)
0.0 0.4 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.3 GO:0098835 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.0 0.1 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.0 1.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.8 GO:0099634 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 0.9 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.1 GO:0005871 kinesin complex(GO:0005871)
0.0 1.2 GO:0031201 SNARE complex(GO:0031201)
0.0 0.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.9 GO:0030141 secretory granule(GO:0030141)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.7 GO:0031514 motile cilium(GO:0031514)
0.0 0.2 GO:0032591 dendritic spine membrane(GO:0032591)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.9 GO:0031852 mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.3 0.8 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.2 1.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.2 2.3 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.2 1.3 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.7 GO:0005536 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.5 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 1.7 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 1.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 2.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 1.9 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.1 0.3 GO:0030626 U12 snRNA binding(GO:0030626)
0.1 1.2 GO:0045159 myosin II binding(GO:0045159)
0.1 0.2 GO:1990174 phosphodiesterase decapping endonuclease activity(GO:1990174)
0.1 1.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.6 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.7 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 1.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 1.1 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 1.6 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.8 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.4 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.9 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.1 GO:0060182 apelin receptor activity(GO:0060182)
0.0 0.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 0.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 1.1 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 0.1 GO:0070095 6-phosphofructokinase activity(GO:0003872) fructose-6-phosphate binding(GO:0070095)
0.0 0.7 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.5 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.5 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.2 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.6 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.7 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.5 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 1.0 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.5 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.4 PID FOXO PATHWAY FoxO family signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 1.2 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 2.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 0.2 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
0.0 0.8 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.9 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 0.6 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.7 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.4 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 0.1 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.5 REACTOME SIGNALING BY NOTCH1 Genes involved in Signaling by NOTCH1
0.0 0.1 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.5 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation