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PRJNA207719: Tissue specific transcriptome profiling
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Results for arxa
Z-value: 1.25
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Transcription factors associated with arxa
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| arxa | dr11_v1_chr24_-_23942722_23942722 | -0.84 | 7.8e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr22_+_11775269 Show fit | 1.83 |
ENSDART00000140272
|
keratin 96 |
|
| chr3_-_59297532 Show fit | 1.26 |
ENSDART00000187991
|
|
|
| chr20_-_37813863 Show fit | 1.22 |
ENSDART00000147529
|
basic leucine zipper transcription factor, ATF-like 3 |
|
| chr4_-_9891874 Show fit | 1.18 |
ENSDART00000067193
|
adrenomedullin 2a |
|
| chr9_-_9415000 Show fit | 1.09 |
ENSDART00000146210
|
si:ch211-214p13.9 |
|
| chr12_-_35830625 Show fit | 0.91 |
ENSDART00000180028
|
|
|
| chr25_-_21031007 Show fit | 0.81 |
ENSDART00000138985
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a |
|
| chr12_+_22580579 Show fit | 0.78 |
ENSDART00000171725
ENSDART00000192290 |
capping protein (actin filament), gelsolin-like b |
|
| chr11_+_705727 Show fit | 0.78 |
ENSDART00000165366
|
TIMP metallopeptidase inhibitor 4, tandem duplicate 2 |
|
| chr14_+_901847 Show fit | 0.76 |
ENSDART00000166991
|
si:ch73-208h1.2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of arxa
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.9 | GO:0050821 | protein stabilization(GO:0050821) |
| 0.0 | 0.9 | GO:0071222 | cellular response to molecule of bacterial origin(GO:0071219) cellular response to lipopolysaccharide(GO:0071222) |
| 0.0 | 0.9 | GO:0051016 | barbed-end actin filament capping(GO:0051016) |
| 0.0 | 0.9 | GO:0010951 | negative regulation of endopeptidase activity(GO:0010951) |
| 0.1 | 0.8 | GO:0051045 | negative regulation of membrane protein ectodomain proteolysis(GO:0051045) |
| 0.0 | 0.8 | GO:0030183 | B cell differentiation(GO:0030183) |
| 0.1 | 0.7 | GO:0006032 | chitin catabolic process(GO:0006032) |
| 0.0 | 0.7 | GO:0061026 | cardiac muscle tissue regeneration(GO:0061026) |
| 0.0 | 0.7 | GO:0042541 | hemoglobin biosynthetic process(GO:0042541) |
| 0.0 | 0.7 | GO:0033048 | negative regulation of sister chromatid segregation(GO:0033046) negative regulation of mitotic sister chromatid segregation(GO:0033048) negative regulation of mitotic sister chromatid separation(GO:2000816) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.8 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.3 | 1.1 | GO:0019815 | B cell receptor complex(GO:0019815) |
| 0.0 | 0.8 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.0 | 0.7 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) cytosolic ribosome(GO:0022626) |
| 0.0 | 0.6 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.0 | 0.4 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
| 0.0 | 0.4 | GO:0031105 | septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156) |
| 0.0 | 0.3 | GO:0061617 | MICOS complex(GO:0061617) |
| 0.0 | 0.3 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.0 | 0.3 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.9 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
| 0.1 | 0.8 | GO:0031821 | G-protein coupled serotonin receptor binding(GO:0031821) |
| 0.1 | 0.8 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.0 | 0.8 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 0.1 | 0.7 | GO:0004568 | chitinase activity(GO:0004568) |
| 0.0 | 0.6 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
| 0.0 | 0.6 | GO:0043236 | laminin binding(GO:0043236) |
| 0.1 | 0.5 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
| 0.1 | 0.5 | GO:0003854 | 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) |
| 0.0 | 0.5 | GO:0019957 | chemokine binding(GO:0019956) C-C chemokine binding(GO:0019957) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.0 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.0 | 1.0 | PID P53 REGULATION PATHWAY | p53 pathway |
| 0.1 | 0.6 | SA FAS SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
| 0.0 | 0.6 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
| 0.0 | 0.5 | PID EPO PATHWAY | EPO signaling pathway |
| 0.0 | 0.4 | PID EPHA FWDPATHWAY | EPHA forward signaling |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.8 | REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 | Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 |
| 0.0 | 0.7 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
| 0.0 | 0.6 | REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
| 0.0 | 0.6 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.1 | 0.5 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.0 | 0.5 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.0 | 0.5 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 0.0 | 0.5 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.0 | 0.4 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.0 | 0.3 | REACTOME PLATELET SENSITIZATION BY LDL | Genes involved in Platelet sensitization by LDL |