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PRJNA207719: Tissue specific transcriptome profiling
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Results for arntl1a+arntl1b
Z-value: 1.16
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Transcription factors associated with arntl1a+arntl1b
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
| ENSDARG00000006791 | aryl hydrocarbon receptor nuclear translocator-like 1a | |
| ENSDARG00000035732 | aryl hydrocarbon receptor nuclear translocator-like 1b | |
| ENSDARG00000114562 | aryl hydrocarbon receptor nuclear translocator-like 1b |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| arntl1b | dr11_v1_chr7_+_66048102_66048102 | 0.79 | 1.1e-01 | Click! |
| arntl1a | dr11_v1_chr25_-_17918536_17918536 | 0.37 | 5.4e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr4_+_13696537 Show fit | 1.60 |
ENSDART00000109195
ENSDART00000122041 ENSDART00000192554 |
neuronal cell adhesion molecule a |
|
| chr7_+_48999723 Show fit | 1.52 |
ENSDART00000182699
ENSDART00000166329 |
si:ch211-288d18.1 |
|
| chr24_-_7632187 Show fit | 1.21 |
ENSDART00000041714
|
ATPase H+ transporting V0 subunit a1b |
|
| chr10_-_6775271 Show fit | 1.19 |
ENSDART00000110735
|
zgc:194281 |
|
| chr24_-_33756003 Show fit | 0.91 |
ENSDART00000079283
|
transmembrane protein with EGF-like and two follistatin-like domains 1b |
|
| chr13_+_421231 Show fit | 0.91 |
ENSDART00000188212
ENSDART00000017854 |
leucine-rich, glioma inactivated 1a |
|
| chr9_+_42095220 Show fit | 0.89 |
ENSDART00000148317
ENSDART00000134431 |
poly(rC) binding protein 3 |
|
| chr7_-_13381129 Show fit | 0.89 |
ENSDART00000164326
|
si:ch73-119p20.1 |
|
| chr25_+_25123385 Show fit | 0.86 |
ENSDART00000163892
|
lactate dehydrogenase A4 |
|
| chr10_+_23022263 Show fit | 0.86 |
ENSDART00000138955
|
si:dkey-175g6.2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of arntl1a+arntl1b
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.5 | GO:0090630 | activation of GTPase activity(GO:0090630) |
| 0.0 | 1.3 | GO:0042147 | retrograde transport, endosome to Golgi(GO:0042147) |
| 0.0 | 1.0 | GO:0034446 | substrate adhesion-dependent cell spreading(GO:0034446) |
| 0.0 | 0.9 | GO:0021549 | cerebellum development(GO:0021549) |
| 0.1 | 0.8 | GO:0099560 | synaptic membrane adhesion(GO:0099560) |
| 0.0 | 0.8 | GO:0048923 | posterior lateral line neuromast hair cell differentiation(GO:0048923) |
| 0.0 | 0.8 | GO:0070831 | basement membrane assembly(GO:0070831) |
| 0.2 | 0.7 | GO:0046166 | methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166) |
| 0.1 | 0.7 | GO:0042766 | nucleosome mobilization(GO:0042766) |
| 0.1 | 0.7 | GO:0051452 | vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.3 | GO:0033179 | proton-transporting V-type ATPase, V0 domain(GO:0033179) |
| 0.0 | 1.0 | GO:0005604 | basement membrane(GO:0005604) |
| 0.3 | 0.8 | GO:0030906 | retromer, cargo-selective complex(GO:0030906) |
| 0.0 | 0.8 | GO:0043256 | basal lamina(GO:0005605) laminin complex(GO:0043256) |
| 0.1 | 0.7 | GO:0016589 | NURF complex(GO:0016589) |
| 0.1 | 0.7 | GO:0000306 | extrinsic component of vacuolar membrane(GO:0000306) |
| 0.0 | 0.7 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 0.0 | 0.6 | GO:0005778 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
| 0.0 | 0.5 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 0.0 | 0.5 | GO:0032589 | neuron projection membrane(GO:0032589) dendrite membrane(GO:0032590) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.9 | GO:0004459 | L-lactate dehydrogenase activity(GO:0004459) |
| 0.0 | 0.9 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.2 | 0.7 | GO:0008929 | triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929) |
| 0.0 | 0.7 | GO:0051117 | ATPase binding(GO:0051117) |
| 0.0 | 0.7 | GO:0016229 | steroid dehydrogenase activity(GO:0016229) |
| 0.0 | 0.7 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.1 | 0.6 | GO:0003835 | beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835) |
| 0.0 | 0.6 | GO:0046961 | proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
| 0.0 | 0.6 | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity(GO:0003755) |
| 0.2 | 0.5 | GO:0031701 | angiotensin receptor binding(GO:0031701) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.9 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.0 | 0.8 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.0 | 0.5 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.0 | 0.2 | PID S1P S1P4 PATHWAY | S1P4 pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.1 | REACTOME PYRUVATE METABOLISM | Genes involved in Pyruvate metabolism |
| 0.2 | 0.8 | REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |
| 0.0 | 0.8 | REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
| 0.0 | 0.8 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
| 0.1 | 0.6 | REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.1 | 0.6 | REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
| 0.0 | 0.5 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 0.0 | 0.4 | REACTOME INSULIN RECEPTOR RECYCLING | Genes involved in Insulin receptor recycling |
| 0.0 | 0.4 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 0.0 | 0.2 | REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING | Genes involved in Role of second messengers in netrin-1 signaling |