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PRJNA207719: Tissue specific transcriptome profiling
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Results for arid5a+arid6
Z-value: 0.70
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Transcription factors associated with arid5a+arid6
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| arid6 | dr11_v1_chr21_+_11248448_11248448 | 0.97 | 5.1e-03 | Click! |
| arid5a | dr11_v1_chr8_+_52377516_52377516 | 0.71 | 1.8e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr4_-_8043839 Show fit | 0.60 |
ENSDART00000190047
ENSDART00000057567 |
si:ch211-240l19.5 |
|
| chr9_+_33207574 Show fit | 0.50 |
ENSDART00000055897
ENSDART00000166030 |
si:ch211-125e6.11 |
|
| chr3_+_57820913 Show fit | 0.44 |
ENSDART00000168101
|
|
|
| chr15_-_452347 Show fit | 0.43 |
ENSDART00000115233
|
V-set and transmembrane domain containing 5 |
|
| chr12_+_46462090 Show fit | 0.41 |
ENSDART00000130748
|
|
|
| chr12_+_46404307 Show fit | 0.41 |
ENSDART00000185011
|
|
|
| chr12_+_46512881 Show fit | 0.38 |
ENSDART00000105454
|
|
|
| chr24_-_26328721 Show fit | 0.36 |
ENSDART00000125468
|
apolipoprotein Db |
|
| chr16_-_46660680 Show fit | 0.34 |
ENSDART00000159209
ENSDART00000191929 |
transmembrane protein 176l.4 |
|
| chr12_+_46483618 Show fit | 0.34 |
ENSDART00000186970
|
|
Network of associatons between targets according to the STRING database.
First level regulatory network of arid5a+arid6
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | GO:0007568 | aging(GO:0007568) |
| 0.1 | 0.2 | GO:0045649 | regulation of macrophage differentiation(GO:0045649) |
| 0.1 | 0.2 | GO:1904667 | negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667) |
| 0.1 | 0.2 | GO:0021564 | vagus nerve development(GO:0021564) |
| 0.0 | 0.2 | GO:0010693 | regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693) |
| 0.0 | 0.2 | GO:0072677 | eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677) |
| 0.0 | 0.2 | GO:0045110 | intermediate filament bundle assembly(GO:0045110) |
| 0.0 | 0.2 | GO:0070493 | thrombin receptor signaling pathway(GO:0070493) |
| 0.0 | 0.2 | GO:0050764 | regulation of phagocytosis(GO:0050764) |
| 0.0 | 0.2 | GO:2000251 | positive regulation of actin cytoskeleton reorganization(GO:2000251) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | GO:0070652 | HAUS complex(GO:0070652) |
| 0.0 | 0.2 | GO:0061702 | inflammasome complex(GO:0061702) |
| 0.0 | 0.2 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.0 | 0.2 | GO:0000796 | condensin complex(GO:0000796) |
| 0.0 | 0.2 | GO:0005833 | hemoglobin complex(GO:0005833) |
| 0.0 | 0.2 | GO:0035101 | FACT complex(GO:0035101) |
| 0.0 | 0.2 | GO:0030057 | desmosome(GO:0030057) |
| 0.0 | 0.1 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
| 0.0 | 0.1 | GO:1990077 | primosome complex(GO:1990077) |
| 0.0 | 0.1 | GO:0070319 | Golgi to plasma membrane transport vesicle(GO:0070319) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | GO:0070548 | L-glutamine aminotransferase activity(GO:0070548) |
| 0.0 | 0.2 | GO:0019863 | IgE binding(GO:0019863) immunoglobulin binding(GO:0019865) |
| 0.0 | 0.2 | GO:0070891 | lipoteichoic acid binding(GO:0070891) |
| 0.0 | 0.2 | GO:0015057 | thrombin receptor activity(GO:0015057) |
| 0.0 | 0.2 | GO:0008199 | ferric iron binding(GO:0008199) |
| 0.0 | 0.2 | GO:0097200 | cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200) |
| 0.0 | 0.2 | GO:0019825 | oxygen transporter activity(GO:0005344) oxygen binding(GO:0019825) |
| 0.0 | 0.2 | GO:0008417 | fucosyltransferase activity(GO:0008417) |
| 0.0 | 0.1 | GO:0098809 | nitrite reductase activity(GO:0098809) |
| 0.0 | 0.1 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.0 | 0.1 | PID IL12 STAT4 PATHWAY | IL12 signaling mediated by STAT4 |
| 0.0 | 0.1 | SIG IL4RECEPTOR IN B LYPHOCYTES | Genes related to IL4 rceptor signaling in B lymphocytes |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.7 | REACTOME INTERFERON GAMMA SIGNALING | Genes involved in Interferon gamma signaling |
| 0.0 | 0.3 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 0.0 | 0.3 | REACTOME EXTENSION OF TELOMERES | Genes involved in Extension of Telomeres |
| 0.0 | 0.2 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.0 | 0.2 | REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR | Genes involved in Trafficking and processing of endosomal TLR |
| 0.0 | 0.1 | REACTOME ACYL CHAIN REMODELLING OF PG | Genes involved in Acyl chain remodelling of PG |
| 0.0 | 0.1 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 0.0 | 0.1 | REACTOME TRANSPORT OF ORGANIC ANIONS | Genes involved in Transport of organic anions |
| 0.0 | 0.1 | REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
| 0.0 | 0.0 | REACTOME ACYL CHAIN REMODELLING OF PI | Genes involved in Acyl chain remodelling of PI |