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PRJNA207719: Tissue specific transcriptome profiling
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Results for arid3a+arid3b+arid3c
Z-value: 1.21
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Transcription factors associated with arid3a+arid3b+arid3c
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
| ENSDARG00000067729 | AT rich interactive domain 3C (BRIGHT-like) | |
| ENSDARG00000070843 | AT rich interactive domain 3A (BRIGHT-like) | |
| ENSDARG00000104034 | AT rich interactive domain 3B (BRIGHT-like) | |
| ENSDARG00000114447 | AT rich interactive domain 3C (BRIGHT-like) |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| arid3c | dr11_v1_chr5_+_41322783_41322783 | 0.89 | 4.3e-02 | Click! |
| arid3b | dr11_v1_chr25_-_29072162_29072162 | -0.66 | 2.3e-01 | Click! |
| arid3a | dr11_v1_chr11_+_5681762_5681762 | 0.65 | 2.4e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr19_-_3167729 Show fit | 2.39 |
ENSDART00000110763
ENSDART00000145710 ENSDART00000074620 ENSDART00000105174 |
starmaker |
|
| chr8_+_3820134 Show fit | 2.35 |
ENSDART00000122454
|
citron rho-interacting serine/threonine kinase b |
|
| chr5_+_70155935 Show fit | 1.93 |
ENSDART00000165570
|
regulator of G protein signaling 3a |
|
| chr18_-_47662696 Show fit | 1.90 |
ENSDART00000184260
|
|
|
| chr2_-_9489611 Show fit | 1.81 |
ENSDART00000146715
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 |
|
| chr1_+_7517454 Show fit | 1.67 |
ENSDART00000016139
|
LanC antibiotic synthetase component C-like 1 (bacterial) |
|
| chr1_+_31112436 Show fit | 1.66 |
ENSDART00000075340
|
eukaryotic translation elongation factor 1 alpha 1b |
|
| chr2_-_9059955 Show fit | 1.26 |
ENSDART00000022768
|
adenylate kinase 5 |
|
| chr19_+_4139065 Show fit | 1.09 |
ENSDART00000172524
|
si:dkey-218f9.10 |
|
| chr15_+_39096736 Show fit | 1.05 |
ENSDART00000129511
ENSDART00000014877 |
roundabout, axon guidance receptor, homolog 2 (Drosophila) |
Network of associatons between targets according to the STRING database.
First level regulatory network of arid3a+arid3b+arid3c
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 2.4 | GO:0045299 | otolith mineralization(GO:0045299) |
| 0.0 | 2.3 | GO:0018107 | peptidyl-threonine phosphorylation(GO:0018107) |
| 0.4 | 1.9 | GO:0008591 | regulation of Wnt signaling pathway, calcium modulating pathway(GO:0008591) negative regulation of non-canonical Wnt signaling pathway(GO:2000051) |
| 0.1 | 1.8 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
| 0.0 | 1.2 | GO:1901385 | regulation of voltage-gated calcium channel activity(GO:1901385) |
| 0.0 | 1.2 | GO:0006414 | translational elongation(GO:0006414) |
| 0.0 | 1.2 | GO:0009142 | nucleoside triphosphate biosynthetic process(GO:0009142) |
| 0.2 | 1.1 | GO:0046952 | ketone body catabolic process(GO:0046952) |
| 0.1 | 1.1 | GO:0050975 | sensory perception of touch(GO:0050975) |
| 0.0 | 1.1 | GO:0006904 | vesicle docking involved in exocytosis(GO:0006904) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.7 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
| 0.0 | 0.5 | GO:0030496 | midbody(GO:0030496) |
| 0.0 | 0.4 | GO:0000407 | pre-autophagosomal structure(GO:0000407) |
| 0.0 | 0.4 | GO:0031594 | neuromuscular junction(GO:0031594) |
| 0.1 | 0.3 | GO:0044233 | ER-mitochondrion membrane contact site(GO:0044233) |
| 0.0 | 0.3 | GO:0000439 | core TFIIH complex(GO:0000439) |
| 0.0 | 0.3 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
| 0.0 | 0.3 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.0 | 0.3 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 0.0 | 0.3 | GO:0032420 | stereocilium(GO:0032420) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.8 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
| 0.3 | 1.7 | GO:0043295 | glutathione binding(GO:0043295) |
| 0.0 | 1.7 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.0 | 1.3 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
| 0.2 | 1.1 | GO:0008260 | 3-oxoacid CoA-transferase activity(GO:0008260) |
| 0.1 | 0.9 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
| 0.0 | 0.9 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.0 | 0.8 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
| 0.1 | 0.7 | GO:0008281 | sulfonylurea receptor activity(GO:0008281) |
| 0.1 | 0.7 | GO:0004687 | myosin light chain kinase activity(GO:0004687) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.5 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.0 | 0.4 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.0 | 0.3 | PID IL8 CXCR2 PATHWAY | IL8- and CXCR2-mediated signaling events |
| 0.0 | 0.2 | PID CXCR3 PATHWAY | CXCR3-mediated signaling events |
| 0.0 | 0.1 | PID AR NONGENOMIC PATHWAY | Nongenotropic Androgen signaling |
| 0.0 | 0.1 | PID IL5 PATHWAY | IL5-mediated signaling events |
| 0.0 | 0.1 | PID S1P S1P4 PATHWAY | S1P4 pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.8 | REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.1 | 1.3 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.0 | 1.1 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.0 | 0.7 | REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
| 0.0 | 0.6 | REACTOME SIGNAL ATTENUATION | Genes involved in Signal attenuation |
| 0.0 | 0.5 | REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT | Genes involved in ABC-family proteins mediated transport |
| 0.0 | 0.4 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 0.0 | 0.4 | REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX | Genes involved in Formation of the HIV-1 Early Elongation Complex |
| 0.1 | 0.3 | REACTOME ACYL CHAIN REMODELLING OF PI | Genes involved in Acyl chain remodelling of PI |
| 0.0 | 0.3 | REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS | Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis |