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PRJNA207719: Tissue specific transcriptome profiling

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Results for TCF4_id4_mespaa+mespab+mespba+mespbb

Z-value: 1.48

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Transcription factors associated with TCF4_id4_mespaa+mespab+mespba+mespbb

Gene Symbol Gene ID Gene Info
ENSDARG00000107408 transcription factor 4
ENSDARG00000045131 inhibitor of DNA binding 4
ENSDARG00000017078 mesoderm posterior aa
ENSDARG00000030347 mesoderm posterior ba
ENSDARG00000068761 mesoderm posterior ab
ENSDARG00000097947 mesoderm posterior bb
ENSDARG00000110553 mesoderm posterior ba
ENSDARG00000114890 mesoderm posterior aa

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mespaadr11_v1_chr7_+_15324830_15324830-0.829.0e-02Click!
id4dr11_v1_chr16_-_9980402_9980402-0.701.9e-01Click!
TCF4dr11_v1_chr21_+_1381276_1381276-0.444.5e-01Click!
mespbbdr11_v1_chr25_-_11026907_11026907-0.424.8e-01Click!

Activity profile of TCF4_id4_mespaa+mespab+mespba+mespbb motif

Sorted Z-values of TCF4_id4_mespaa+mespab+mespba+mespbb motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_48312109 1.26 ENSDART00000161103
si:ch73-359m17.9
chr16_-_36834505 1.07 ENSDART00000141275
ENSDART00000139588
ENSDART00000041993
purine nucleoside phosphorylase 4b
chr20_-_42702832 1.01 ENSDART00000134689
ENSDART00000045816
plasminogen
chr2_-_22688651 0.77 ENSDART00000013863
alanine-glyoxylate aminotransferase b
chr7_+_7048245 0.77 ENSDART00000001649
actinin alpha 3b
chr24_-_25691020 0.69 ENSDART00000015391
cholinergic receptor, nicotinic, delta (muscle)
chr1_+_30422143 0.66 ENSDART00000033024
transmembrane protein 41ab
chr7_+_39446247 0.64 ENSDART00000033610
ENSDART00000099015
troponin T type 3b (skeletal, fast)
chr9_+_310331 0.64 ENSDART00000172446
ENSDART00000187731
ENSDART00000193970
SH3 and cysteine rich domain 3
chr25_-_4146947 0.61 ENSDART00000129268
fatty acid desaturase 2
chr22_-_25612680 0.61 ENSDART00000114167
si:ch211-12h2.8
chr1_-_18811517 0.60 ENSDART00000142026
si:dkey-167i21.2
chr7_+_58751504 0.59 ENSDART00000024185
zgc:56231
chr21_-_43666420 0.57 ENSDART00000139008
ENSDART00000183996
ENSDART00000183395
si:dkey-229d11.3
si:dkey-229d11.5
chr7_+_61184551 0.56 ENSDART00000190788
zgc:194930
chr11_-_37995501 0.56 ENSDART00000192096
solute carrier family 41 (magnesium transporter), member 1
chr3_+_42923275 0.55 ENSDART00000168228
transmembrane protein 184a
chr21_-_30293224 0.55 ENSDART00000101051
stem-loop binding protein 2
chr21_-_34261677 0.55 ENSDART00000124649
ENSDART00000172381
ENSDART00000064320
ALG13, UDP-N-acetylglucosaminyltransferase subunit
chr25_-_32311048 0.54 ENSDART00000181806
ENSDART00000086334

chr10_-_25217347 0.54 ENSDART00000036906
karyopherin alpha 7 (importin alpha 8)
chr6_+_29305190 0.54 ENSDART00000078647
si:ch211-201h21.5
chr9_-_34269066 0.52 ENSDART00000059955
immunoglobulin-like domain containing receptor 1b
chr9_+_307863 0.52 ENSDART00000163474
SH3 and cysteine rich domain 3
chr5_-_38451082 0.51 ENSDART00000136428
cholinergic receptor, nicotinic, epsilon
chr15_-_43164591 0.51 ENSDART00000171305
adaptor-related protein complex 1, sigma 3 subunit, a
chr16_+_52512025 0.50 ENSDART00000056095
fatty acid binding protein 10a, liver basic
chr13_-_21672131 0.50 ENSDART00000067537
ELOVL family member 6, elongation of long chain fatty acids like
chr2_-_50225411 0.49 ENSDART00000147117
ENSDART00000000042
MCM6 minichromosome maintenance deficient 6, like
chr6_-_40058686 0.49 ENSDART00000103240
urocanate hydratase 1
chr23_+_39854566 0.49 ENSDART00000190423
ENSDART00000164473
ENSDART00000161881
si:ch73-217b7.1
chr14_+_15155684 0.48 ENSDART00000167966
zgc:158852
chr22_-_17677947 0.47 ENSDART00000139911
tight junction protein 3
chr2_-_47620806 0.47 ENSDART00000038228
adaptor-related protein complex 1, sigma 3 subunit, b
chr3_+_32526799 0.47 ENSDART00000185755
si:ch73-367p23.2
chr3_+_32526263 0.47 ENSDART00000150897
si:ch73-367p23.2
chr12_-_23365737 0.47 ENSDART00000170376
membrane protein, palmitoylated 7a (MAGUK p55 subfamily member 7)
chr21_-_25756119 0.46 ENSDART00000002341
claudin c
chr6_+_153146 0.46 ENSDART00000097468
zinc finger, GATA-like protein 1
chr1_+_24387659 0.46 ENSDART00000130356
quinoid dihydropteridine reductase b2
chr4_-_77557279 0.44 ENSDART00000180113

chr20_+_26556372 0.44 ENSDART00000187179
ENSDART00000157291
interferon regulatory factor 4b
chr2_+_6253246 0.44 ENSDART00000058256
ENSDART00000076700
zona pellucida glycoprotein 3b
chr7_+_6969909 0.43 ENSDART00000189886
actinin alpha 3b
chr14_+_11458044 0.43 ENSDART00000186425
si:ch211-153b23.5
chr23_+_553396 0.43 ENSDART00000034707
LSM family member 14B
chr15_-_3277635 0.43 ENSDART00000189094
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15a
chr3_+_14641962 0.43 ENSDART00000091070
zgc:158403
chr2_+_11031360 0.43 ENSDART00000180020
ENSDART00000145093
acyl-CoA thioesterase 11a
chr9_+_7358749 0.42 ENSDART00000081660
Indian hedgehog homolog a
chr6_+_60112200 0.42 ENSDART00000008243
PRELI domain containing 3
chr9_-_39005317 0.42 ENSDART00000014207
myosin, light chain 1, alkali; skeletal, fast
chr17_-_30473374 0.41 ENSDART00000155021
si:ch211-175f11.5
chr12_+_13091842 0.40 ENSDART00000185477
ENSDART00000181435
ENSDART00000124799
si:ch211-103b1.2
chr17_-_2596125 0.40 ENSDART00000175740
zona pellucida glycoprotein 3, tandem duplicate 2
chr21_-_26114886 0.40 ENSDART00000139320
NIPA-like domain containing 4
chr9_-_22892838 0.39 ENSDART00000143888
nebulin
chr2_-_41942666 0.39 ENSDART00000075673
Epstein-Barr virus induced 3
chr16_-_42066523 0.38 ENSDART00000180538
ENSDART00000058620
zona pellucida glycoprotein 3d tandem duplicate 1
chr23_+_6077503 0.38 ENSDART00000081714
ENSDART00000139834
myosin binding protein Ha
chr22_+_661711 0.38 ENSDART00000113795
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr2_+_27855346 0.38 ENSDART00000175159
ENSDART00000192645
bucky ball
chr14_+_22297257 0.37 ENSDART00000113676
ATPase phospholipid transporting 10B
chr5_-_69212184 0.37 ENSDART00000053963
methionine adenosyltransferase II, alpha b
chr22_+_25249193 0.37 ENSDART00000171851
si:ch211-226h8.11
chr19_+_48117995 0.37 ENSDART00000170865
NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 1
chr4_+_72797711 0.37 ENSDART00000190934
ENSDART00000163236
myelin regulatory factor-like
chr6_+_45918981 0.36 ENSDART00000149642
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr17_+_53294228 0.36 ENSDART00000158172
si:ch1073-416d2.3
chr22_+_661505 0.36 ENSDART00000149460
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr20_-_21672970 0.36 ENSDART00000133286
si:ch211-207i1.2
chr10_+_38775959 0.36 ENSDART00000192990
Down syndrome cell adhesion molecule a
chr10_+_38775408 0.36 ENSDART00000125045
Down syndrome cell adhesion molecule a
chr22_+_25248961 0.36 ENSDART00000143079
si:ch211-226h8.11
chr22_-_14128716 0.36 ENSDART00000140323
si:ch211-246m6.4
chr10_+_34001444 0.35 ENSDART00000149934
klotho
chr2_-_35566938 0.35 ENSDART00000029006
ENSDART00000077178
ENSDART00000125298
tenascin N
chr14_-_46198373 0.35 ENSDART00000031640
ENSDART00000132966
zgc:113425
chr12_+_46543572 0.35 ENSDART00000167510
HID1 domain containing b
chr7_+_57089354 0.35 ENSDART00000140702
secretory carrier membrane protein 2, like
chr10_-_13116337 0.34 ENSDART00000164568
muscle, skeletal, receptor tyrosine kinase
chr24_+_35564668 0.34 ENSDART00000122734
CCAAT/enhancer binding protein (C/EBP), delta
chr2_+_57801960 0.33 ENSDART00000147966
si:dkeyp-68b7.10
chr7_+_20471315 0.33 ENSDART00000173714
si:dkey-19b23.13
chr14_+_11457500 0.33 ENSDART00000169202
si:ch211-153b23.5
chr2_+_17181777 0.32 ENSDART00000112063
prostaglandin E receptor 4 (subtype EP4) c
chr8_+_15254564 0.32 ENSDART00000024433
solute carrier family 5 (sodium/sugar cotransporter), member 9
chr11_+_329687 0.32 ENSDART00000172882
cytochrome P450, family 27, subfamily B, polypeptide 1
chr15_-_3282220 0.32 ENSDART00000092942
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15a
chr12_+_6041575 0.32 ENSDART00000091868
glucose-6-phosphatase a, catalytic subunit, tandem duplicate 2
chr15_+_29025090 0.32 ENSDART00000131755
si:ch211-137a8.2
chr2_+_27855102 0.31 ENSDART00000150330
bucky ball
chr7_+_61184104 0.31 ENSDART00000110671
zgc:194930
chr2_+_394166 0.31 ENSDART00000155733
myosin light chain kinase family, member 4a
chr5_-_69948099 0.31 ENSDART00000034639
ENSDART00000191111
UDP glucuronosyltransferase 2 family, polypeptide A4
chr20_-_27325258 0.31 ENSDART00000152917
ankyrin repeat and SOCS box containing 2a, tandem duplicate 1
chr3_+_25849560 0.31 ENSDART00000007119
major facilitator superfamily domain containing 6-like
chr18_+_45666489 0.30 ENSDART00000180147
ENSDART00000151351
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr23_-_19684721 0.30 ENSDART00000184325
zgc:193598
chr13_-_12581388 0.30 ENSDART00000079655
glutamyl aminopeptidase
chr15_-_33964897 0.30 ENSDART00000172075
ENSDART00000158126
ENSDART00000160456
lipolysis stimulated lipoprotein receptor
chr20_+_26556174 0.30 ENSDART00000138492
interferon regulatory factor 4b
chr2_-_24402341 0.30 ENSDART00000155442
ENSDART00000088572
zgc:154006
chr13_-_34683370 0.30 ENSDART00000113661
kinesin family member 16Bb
chr2_+_11028923 0.30 ENSDART00000076725
acyl-CoA thioesterase 11a
chr10_-_15053507 0.30 ENSDART00000157446
ENSDART00000170441
si:ch211-95j8.5
chr10_+_3520256 0.29 ENSDART00000003242
zgc:123275
chr5_-_37900350 0.29 ENSDART00000084839
ENSDART00000084841
ENSDART00000133437
transmembrane protease, serine 13b
chr6_+_6780873 0.29 ENSDART00000011865
Sec23 homolog B, COPII coat complex component
chr17_-_2595736 0.29 ENSDART00000128797
zona pellucida glycoprotein 3, tandem duplicate 2
chr15_+_29024895 0.29 ENSDART00000141164
ENSDART00000144126
si:ch211-137a8.2
chr19_+_19767567 0.28 ENSDART00000169074
homeobox A3a
chr7_-_50367326 0.28 ENSDART00000141926
protein regulator of cytokinesis 1b
chr7_+_41303572 0.28 ENSDART00000012692
regulator of G protein signaling 9 binding protein
chr3_+_17456428 0.28 ENSDART00000090676
ENSDART00000182082
si:ch211-210g13.5
chr1_-_12027 0.28 ENSDART00000164359
ribosomal protein L24
chr4_-_68563862 0.28 ENSDART00000182970

chr14_-_33277743 0.27 ENSDART00000048130
START domain containing 14
chr3_+_22273123 0.27 ENSDART00000044157
sodium channel, voltage-gated, type IV, alpha, b
chr21_-_25741096 0.27 ENSDART00000181756
claudin h
chr6_-_39270851 0.27 ENSDART00000148839
Rho guanine nucleotide exchange factor (GEF) 25b
chr11_+_11175814 0.27 ENSDART00000183864

chr24_-_25244637 0.27 ENSDART00000153798
HERV-H LTR-associating 2b, tandem duplicate 2
chr17_-_25331439 0.27 ENSDART00000155422
ENSDART00000082324
zona pellucida protein C
chr19_-_10771558 0.27 ENSDART00000085165
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3, tandem duplicate 2
chr6_+_42338309 0.26 ENSDART00000015277
glutathione peroxidase 1b
chr16_-_12723738 0.26 ENSDART00000080414
SH3 domain binding kinase family, member 3
chr7_+_30392613 0.26 ENSDART00000075508
lipase, hepatic a
chr8_+_45334255 0.26 ENSDART00000126848
ENSDART00000134161
ENSDART00000142322
ENSDART00000145011
ENSDART00000183560
poly(A) binding protein, cytoplasmic 1-like
chr7_-_53117131 0.26 ENSDART00000169211
ENSDART00000168890
ENSDART00000172179
ENSDART00000167882
cadherin 1, type 1, E-cadherin (epithelial)
chr5_-_37047147 0.26 ENSDART00000097712
ENSDART00000158974
finTRIM family, member 99
chr7_-_55648336 0.26 ENSDART00000147792
ENSDART00000135304
ENSDART00000131923
poly(A) binding protein, nuclear 1-like (cytoplasmic)
chr21_-_7928101 0.26 ENSDART00000151543
ENSDART00000114982
coagulation factor II (thrombin) receptor-like 1, tandem duplicate 2
chr21_-_25741411 0.26 ENSDART00000101211
claudin h
chr1_+_12009673 0.25 ENSDART00000080100
solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
chr23_-_32156278 0.25 ENSDART00000157479
nuclear receptor subfamily 4, group A, member 1
chr2_+_11029138 0.25 ENSDART00000138737
ENSDART00000081058
ENSDART00000153662
acyl-CoA thioesterase 11a
chr7_+_29951997 0.25 ENSDART00000173453
alpha-tropomyosin
chr7_-_48251234 0.25 ENSDART00000024062
ENSDART00000098904
cytoplasmic polyadenylation element binding protein 1b
chr24_-_33703504 0.25 ENSDART00000079292
caveolae associated protein 4b
chr12_+_45676667 0.25 ENSDART00000016553
si:ch73-111m19.2
chr19_+_15441022 0.24 ENSDART00000098970
ENSDART00000140276
lin-28 homolog A (C. elegans)
chr21_-_40630650 0.24 ENSDART00000172706
phosphate cytidylyltransferase 1, choline, beta b
chr3_+_36424055 0.24 ENSDART00000170318
si:ch1073-443f11.2
chr16_-_42056137 0.24 ENSDART00000102798
zona pellucida glycoprotein 3d tandem duplicate 2
chr23_-_29824146 0.24 ENSDART00000020616
zgc:194189
chr3_+_62161184 0.24 ENSDART00000090370
ENSDART00000192665
NADPH oxidase organizer 1a
chr20_+_10538025 0.24 ENSDART00000129762
serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1, like
chr7_-_50367642 0.24 ENSDART00000134941
protein regulator of cytokinesis 1b
chr6_-_609880 0.24 ENSDART00000149248
ENSDART00000148867
ENSDART00000149414
ENSDART00000148552
ENSDART00000148391
lectin, galactoside-binding, soluble, 2b
chr15_+_43906043 0.24 ENSDART00000010881
N-acetylated alpha-linked acidic dipeptidase 2
chr5_-_1962500 0.24 ENSDART00000150163
ribosomal protein, large, P0
chr25_-_17395315 0.24 ENSDART00000064596
cytochrome P450, family 2, subfamily X, polypeptide 8
chr10_-_26744131 0.24 ENSDART00000020096
ENSDART00000162710
ENSDART00000179853
fibroblast growth factor 13b
chr11_-_25853212 0.24 ENSDART00000145655
transmembrane protein 51b
chr24_+_10898671 0.23 ENSDART00000106272
si:dkey-37o8.1
chr5_-_6567464 0.23 ENSDART00000184985
tankyrase 1 binding protein 1
chr20_-_53624645 0.23 ENSDART00000083427
ENSDART00000152920
solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29
chr4_+_14981854 0.23 ENSDART00000067046
cation/H+ exchanger protein 1
chr19_+_25504645 0.23 ENSDART00000143292
collagen, type XXVIII, alpha 1a
chr16_+_46725087 0.23 ENSDART00000008920
RAB11a, member RAS oncogene family, like
chr21_-_43636595 0.23 ENSDART00000151115
ENSDART00000151486
ENSDART00000151778
si:ch1073-263o8.2
chr16_-_47381519 0.23 ENSDART00000032188
ENSDART00000150136
si:dkey-256h2.1
chr1_-_29747702 0.23 ENSDART00000133225
ENSDART00000189670
secreted phosphoprotein 2
chr14_+_26546175 0.23 ENSDART00000105932
si:dkeyp-110e4.11
chr7_+_14005111 0.23 ENSDART00000187365
furin (paired basic amino acid cleaving enzyme) a
chr14_-_83154 0.23 ENSDART00000187097

chr24_-_6038025 0.22 ENSDART00000077819
ENSDART00000139216
finTRIM family, member 61
chr5_-_23715861 0.22 ENSDART00000019992
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 1
chr3_-_61205711 0.22 ENSDART00000055062
parvalbumin 1
chr1_-_20593778 0.22 ENSDART00000124770
UDP glycosyltransferase 8
chr22_-_17256573 0.22 ENSDART00000136119
ENSDART00000062891
nephrosis 2, idiopathic, steroid-resistant (podocin)
chr7_+_24628546 0.22 ENSDART00000173745
si:ch211-69e13.6
chr25_-_17587785 0.22 ENSDART00000073679
ENSDART00000146851
zgc:66449
chr16_-_17713859 0.22 ENSDART00000149275
zgc:174935
chr4_-_948776 0.22 ENSDART00000023483
single-minded family bHLH transcription factor 1b
chr10_+_31809226 0.22 ENSDART00000087898
forkhead box O1 b
chr7_+_69841017 0.22 ENSDART00000169107

chr1_-_34450622 0.21 ENSDART00000083736
LIM domain 7b
chr17_+_53292215 0.21 ENSDART00000170686
si:ch1073-416d2.3
chr11_-_34097418 0.21 ENSDART00000028301
ENSDART00000138579
tryptophan 2,3-dioxygenase b
chr7_+_57088920 0.21 ENSDART00000024076
secretory carrier membrane protein 2, like
chr7_+_67699009 0.21 ENSDART00000192810
zgc:162592
chr6_-_13498745 0.21 ENSDART00000027684
ENSDART00000189438
myosin light chain kinase b
chr21_-_20725853 0.21 ENSDART00000114502
si:ch211-22d5.2
chr22_+_22021936 0.21 ENSDART00000149586
guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 1
chr5_-_64355227 0.21 ENSDART00000170787
family with sequence similarity 78, member Aa
chr19_+_2590182 0.21 ENSDART00000162293
si:ch73-345f18.3
chr3_+_14388010 0.21 ENSDART00000171726
ENSDART00000165452
transmembrane protein 56b
chr8_+_32719930 0.21 ENSDART00000145362
hemicentin 2
chr6_+_42918933 0.21 ENSDART00000064896
guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1
chr15_+_20239141 0.21 ENSDART00000101152
ENSDART00000152473
serine peptidase inhibitor, Kunitz type, 2
chr7_+_27455321 0.21 ENSDART00000148417
cytochrome P450, family 2, subfamily R, polypeptide 1
chr17_-_36860988 0.21 ENSDART00000154981
SUMO1/sentrin specific peptidase 6b
chr7_+_55112922 0.21 ENSDART00000073549
snail family zinc finger 3
chr5_-_23855447 0.20 ENSDART00000051541
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 3
chr8_+_53051701 0.20 ENSDART00000131514
NAD kinase a
chr10_-_35149513 0.20 ENSDART00000063434
ENSDART00000131291
receptor-interacting serine-threonine kinase 4
chr8_-_25690966 0.20 ENSDART00000033701
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ga
chr13_-_9442942 0.20 ENSDART00000138833
glutaredoxin, cysteine rich 1

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF4_id4_mespaa+mespab+mespba+mespbb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0042730 fibrinolysis(GO:0042730)
0.3 0.8 GO:1990575 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.2 1.2 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.2 0.5 GO:0043606 formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.2 0.9 GO:0006545 glycine biosynthetic process(GO:0006545)
0.1 0.4 GO:0044321 leptin-mediated signaling pathway(GO:0033210) cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.1 2.2 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 0.9 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.1 0.7 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.1 0.7 GO:0040016 embryonic cleavage(GO:0040016)
0.1 0.3 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.1 0.3 GO:0060292 long term synaptic depression(GO:0060292)
0.1 0.3 GO:0030237 female sex determination(GO:0030237)
0.1 0.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.1 GO:1900048 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.1 0.7 GO:0030104 water homeostasis(GO:0030104)
0.1 0.5 GO:0051231 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231) mitotic spindle midzone assembly(GO:0051256)
0.1 0.3 GO:0071380 response to prostaglandin E(GO:0034695) cellular response to prostaglandin E stimulus(GO:0071380)
0.1 0.2 GO:0009912 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.1 0.2 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.1 0.2 GO:0006844 acyl carnitine transport(GO:0006844)
0.1 0.2 GO:0090008 convergent extension involved in nephron morphogenesis(GO:0072045) hypoblast development(GO:0090008)
0.1 0.6 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 0.5 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 0.4 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.6 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 0.2 GO:0009957 epidermal cell fate specification(GO:0009957)
0.1 0.2 GO:0090234 regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
0.0 0.5 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.2 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.0 0.1 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.1 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
0.0 0.3 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.0 0.2 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.0 0.2 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.3 GO:0010269 response to selenium ion(GO:0010269)
0.0 0.1 GO:1901232 regulation of convergent extension involved in axis elongation(GO:1901232) positive regulation of epiboly involved in gastrulation with mouth forming second(GO:1904088)
0.0 0.1 GO:0065001 specification of axis polarity(GO:0065001)
0.0 0.3 GO:0060149 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.0 0.3 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 0.3 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.2 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.1 GO:0002369 T cell cytokine production(GO:0002369)
0.0 0.2 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.0 0.2 GO:0003241 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.0 0.1 GO:0090435 protein targeting to nuclear inner membrane(GO:0036228) protein localization to nuclear envelope(GO:0090435)
0.0 0.2 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)
0.0 0.1 GO:0072020 proximal straight tubule development(GO:0072020)
0.0 0.1 GO:0042755 eating behavior(GO:0042755)
0.0 0.2 GO:0090497 mesenchymal cell migration(GO:0090497)
0.0 0.1 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.1 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.0 0.4 GO:0042436 tryptophan metabolic process(GO:0006568) tryptophan catabolic process(GO:0006569) indolalkylamine metabolic process(GO:0006586) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
0.0 0.2 GO:0033292 T-tubule organization(GO:0033292)
0.0 0.2 GO:0071305 vitamin D3 metabolic process(GO:0070640) cellular response to vitamin D(GO:0071305)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0002902 B cell apoptotic process(GO:0001783) regulation of B cell apoptotic process(GO:0002902) regulation of lymphocyte apoptotic process(GO:0070228)
0.0 0.1 GO:1904353 positive regulation of telomere maintenance(GO:0032206) regulation of telomere capping(GO:1904353) positive regulation of telomere capping(GO:1904355)
0.0 0.1 GO:2000648 neuroblast division(GO:0055057) positive regulation of stem cell proliferation(GO:2000648)
0.0 0.3 GO:0072098 anterior/posterior pattern specification involved in pronephros development(GO:0034672) anterior/posterior pattern specification involved in kidney development(GO:0072098)
0.0 0.3 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.0 0.3 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.0 0.6 GO:0048922 posterior lateral line neuromast deposition(GO:0048922)
0.0 0.2 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.2 GO:0019388 galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
0.0 0.2 GO:1902514 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.0 0.8 GO:0006942 regulation of striated muscle contraction(GO:0006942)
0.0 0.4 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 0.1 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.5 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.1 GO:0070814 cysteine biosynthetic process from serine(GO:0006535) hydrogen sulfide biosynthetic process(GO:0070814)
0.0 0.2 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.3 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.1 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.4 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.3 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.2 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.1 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.4 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.0 GO:0008207 C21-steroid hormone metabolic process(GO:0008207)
0.0 0.1 GO:0010561 negative regulation of glycoprotein biosynthetic process(GO:0010561) negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) negative regulation of glycoprotein metabolic process(GO:1903019)
0.0 0.1 GO:0048340 paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341)
0.0 0.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.1 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.0 0.7 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 0.2 GO:0040038 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.0 0.2 GO:0050957 equilibrioception(GO:0050957)
0.0 0.5 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.1 GO:0032208 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208)
0.0 0.1 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.4 GO:0051899 membrane depolarization(GO:0051899)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.2 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.4 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.2 GO:0006337 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 0.2 GO:0032262 pyrimidine-containing compound salvage(GO:0008655) pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) pyrimidine nucleoside salvage(GO:0043097) UMP salvage(GO:0044206)
0.0 0.1 GO:0002446 neutrophil mediated immunity(GO:0002446)
0.0 0.3 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.1 GO:0035676 anterior lateral line neuromast hair cell development(GO:0035676)
0.0 0.1 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.0 0.1 GO:0019401 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
0.0 0.2 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.0 0.1 GO:0048939 anterior lateral line nerve glial cell differentiation(GO:0048913) myelination of anterior lateral line nerve axons(GO:0048914) anterior lateral line nerve glial cell development(GO:0048939) anterior lateral line nerve glial cell morphogenesis involved in differentiation(GO:0048940)
0.0 0.1 GO:0006537 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.0 0.1 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.0 0.1 GO:2000725 regulation of cardiocyte differentiation(GO:1905207) regulation of cardiac muscle cell differentiation(GO:2000725)
0.0 0.2 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.1 GO:0008356 asymmetric cell division(GO:0008356)
0.0 0.2 GO:0035588 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 0.2 GO:0030719 P granule organization(GO:0030719)
0.0 0.1 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.0 0.1 GO:0002295 T-helper cell lineage commitment(GO:0002295) T cell lineage commitment(GO:0002360) alpha-beta T cell lineage commitment(GO:0002363) CD4-positive or CD8-positive, alpha-beta T cell lineage commitment(GO:0043369) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373) T-helper 17 type immune response(GO:0072538) T-helper 17 cell differentiation(GO:0072539) T-helper 17 cell lineage commitment(GO:0072540)
0.0 0.5 GO:0009994 oocyte differentiation(GO:0009994)
0.0 0.6 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)
0.0 0.2 GO:0046850 regulation of bone remodeling(GO:0046850)
0.0 0.1 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.2 GO:0048659 smooth muscle cell proliferation(GO:0048659)
0.0 0.2 GO:0046849 bone remodeling(GO:0046849)
0.0 0.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.0 GO:0032640 tumor necrosis factor production(GO:0032640) tumor necrosis factor superfamily cytokine production(GO:0071706)
0.0 0.1 GO:0034435 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.0 0.1 GO:0042554 superoxide anion generation(GO:0042554)
0.0 0.1 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.0 GO:0007351 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.1 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.0 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521) regulation of cellular amine metabolic process(GO:0033238)
0.0 0.2 GO:0016556 mRNA modification(GO:0016556)
0.0 0.2 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 0.0 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.0 0.2 GO:0048796 swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.0 0.1 GO:0002286 T cell activation involved in immune response(GO:0002286)
0.0 0.1 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.1 GO:0038065 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.0 0.1 GO:0089718 L-arginine import(GO:0043091) amino acid import across plasma membrane(GO:0089718) arginine import(GO:0090467) L-arginine import across plasma membrane(GO:0097638) L-arginine transport(GO:1902023) L-arginine import into cell(GO:1902765) amino acid import into cell(GO:1902837) L-arginine transmembrane transport(GO:1903400) arginine transmembrane transport(GO:1903826)
0.0 0.1 GO:1904667 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.0 0.1 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.0 0.1 GO:0018120 peptidyl-arginine ADP-ribosylation(GO:0018120)
0.0 0.0 GO:0042693 muscle cell fate commitment(GO:0042693)
0.0 0.2 GO:0042694 muscle cell fate specification(GO:0042694)
0.0 0.1 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.1 GO:0090113 regulation of COPII vesicle coating(GO:0003400) regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis(GO:0090113)
0.0 0.1 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866) positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.1 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.4 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.1 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.0 0.1 GO:0036344 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.0 0.1 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.0 0.1 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.1 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.0 0.1 GO:2000392 lamellipodium morphogenesis(GO:0072673) regulation of lamellipodium morphogenesis(GO:2000392)
0.0 0.2 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.1 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.1 GO:0021982 pineal gland development(GO:0021982)
0.0 0.7 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.1 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.1 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.0 0.1 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.2 GO:0001840 neural plate development(GO:0001840)
0.0 1.0 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.0 GO:0032185 septin ring organization(GO:0031106) septin cytoskeleton organization(GO:0032185)
0.0 0.2 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.1 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.0 0.3 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.5 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 0.0 GO:0055107 Golgi to secretory granule transport(GO:0055107)
0.0 0.1 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.0 0.2 GO:0034311 diol metabolic process(GO:0034311)
0.0 0.0 GO:0050787 response to mercury ion(GO:0046689) detoxification of mercury ion(GO:0050787)
0.0 0.0 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.0 GO:1990697 protein depalmitoleylation(GO:1990697)
0.0 0.0 GO:0015697 quaternary ammonium group transport(GO:0015697)
0.0 0.2 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 0.1 GO:0070874 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.1 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.1 GO:0021681 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.2 GO:0033391 chromatoid body(GO:0033391)
0.1 1.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 0.4 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 0.7 GO:0032019 mitochondrial cloud(GO:0032019)
0.1 1.3 GO:0030315 T-tubule(GO:0030315)
0.1 0.3 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.8 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.5 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.2 GO:0043073 germ cell nucleus(GO:0043073)
0.0 0.7 GO:0042555 MCM complex(GO:0042555)
0.0 0.1 GO:0031511 Mis6-Sim4 complex(GO:0031511)
0.0 0.7 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.3 GO:0031526 brush border membrane(GO:0031526)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 0.1 GO:0018444 translation release factor complex(GO:0018444)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.1 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 2.0 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 1.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.1 GO:0098645 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 0.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.2 GO:0030057 desmosome(GO:0030057)
0.0 0.0 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.1 GO:0032433 filopodium tip(GO:0032433)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.2 GO:0071564 npBAF complex(GO:0071564)
0.0 0.0 GO:0070195 growth hormone receptor complex(GO:0070195)
0.0 0.9 GO:0005871 kinesin complex(GO:0005871)
0.0 0.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.9 GO:0005581 collagen trimer(GO:0005581)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 1.4 GO:0035804 structural constituent of egg coat(GO:0035804)
0.1 0.8 GO:0032190 acrosin binding(GO:0032190)
0.1 0.5 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155) NADH binding(GO:0070404)
0.1 0.4 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 1.1 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.1 0.9 GO:0005113 patched binding(GO:0005113)
0.1 0.5 GO:1990518 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.1 0.4 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.1 0.8 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 0.5 GO:0032052 bile acid binding(GO:0032052)
0.1 1.3 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 0.2 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1 0.2 GO:0001729 ceramide kinase activity(GO:0001729)
0.1 0.2 GO:0016713 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.1 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1 0.2 GO:0080132 fatty acid alpha-hydroxylase activity(GO:0080132)
0.1 0.4 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.2 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.1 0.2 GO:0015369 calcium:proton antiporter activity(GO:0015369) metal ion:proton antiporter activity(GO:0051139)
0.1 0.3 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 0.2 GO:0004372 glycine hydroxymethyltransferase activity(GO:0004372) serine binding(GO:0070905)
0.1 1.2 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 0.2 GO:0003978 UDP-glucose 4-epimerase activity(GO:0003978)
0.1 0.4 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.4 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.5 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.1 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.2 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.2 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.1 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 0.1 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.0 0.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.4 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.1 GO:0047173 phosphatidylcholine-retinol O-acyltransferase activity(GO:0047173)
0.0 0.3 GO:0038064 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.0 0.4 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.2 GO:0070698 type I activin receptor binding(GO:0070698)
0.0 0.5 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 0.1 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.0 0.2 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.1 GO:0008184 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.0 0.8 GO:0008483 transaminase activity(GO:0008483)
0.0 0.1 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0042806 fucose binding(GO:0042806)
0.0 0.2 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.2 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.1 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.0 0.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.2 GO:0035925 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.1 GO:0070697 activin receptor binding(GO:0070697)
0.0 0.3 GO:0015386 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.1 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.1 GO:0098634 C-X3-C chemokine binding(GO:0019960) protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.0 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.5 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0070888 E-box binding(GO:0070888)
0.0 0.7 GO:0098631 protein binding involved in cell adhesion(GO:0098631) protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.2 GO:0016936 galactoside binding(GO:0016936)
0.0 0.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.4 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.3 GO:0008187 poly-pyrimidine tract binding(GO:0008187) poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.1 GO:0035197 siRNA binding(GO:0035197)
0.0 0.6 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.1 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.0 0.1 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.0 0.1 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.1 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.0 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.0 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.1 GO:0038131 neuregulin receptor activity(GO:0038131) neuregulin binding(GO:0038132)
0.0 0.1 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.0 0.4 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0090556 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.1 GO:1903924 estradiol binding(GO:1903924)
0.0 0.1 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.1 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.0 GO:0015462 protein-transmembrane transporting ATPase activity(GO:0015462)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.1 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.1 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.2 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.0 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
0.0 0.2 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.0 GO:0005463 UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.0 0.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.0 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.0 GO:0004903 growth hormone receptor activity(GO:0004903)
0.0 0.1 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.0 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.0 0.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.6 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.6 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.1 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.1 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.2 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.1 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.4 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.4 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.3 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.3 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.5 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.2 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 1.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 0.6 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 0.2 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.6 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.6 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.4 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.0 0.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.2 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.1 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.1 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.2 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.5 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.3 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism