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PRJNA207719: Tissue specific transcriptome profiling
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Results for BX548005.1+smarcc2
Z-value: 2.10
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Transcription factors associated with BX548005.1+smarcc2
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
| ENSDARG00000077946 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 | |
| ENSDARG00000110907 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| smarcc2 | dr11_v1_chr6_+_39836474_39836474 | 0.93 | 2.4e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr5_+_65536095 Show fit | 1.87 |
ENSDART00000189898
|
si:dkey-21e5.1 |
|
| chr10_+_36037977 Show fit | 1.79 |
ENSDART00000164678
|
katanin p60 subunit A-like 1 |
|
| chr16_+_5774977 Show fit | 1.71 |
ENSDART00000134202
|
cholecystokinin a |
|
| chr8_-_5155545 Show fit | 1.39 |
ENSDART00000056885
|
dihydropyrimidinase like 2 |
|
| chr16_-_34285106 Show fit | 1.38 |
ENSDART00000044235
|
phosphatase and actin regulator 4b |
|
| chr25_+_10458990 Show fit | 1.34 |
ENSDART00000130354
ENSDART00000044738 |
RIC8 guanine nucleotide exchange factor A |
|
| chr18_+_45792035 Show fit | 1.34 |
ENSDART00000135045
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5 |
|
| chr6_-_13449556 Show fit | 1.29 |
ENSDART00000184566
ENSDART00000112883 ENSDART00000185377 |
formin-like 2b |
|
| chr16_+_34523515 Show fit | 1.24 |
ENSDART00000041007
|
stathmin 1b |
|
| chr7_-_36358303 Show fit | 1.23 |
ENSDART00000130028
|
fat mass and obesity associated |
Network of associatons between targets according to the STRING database.
First level regulatory network of BX548005.1+smarcc2
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.8 | GO:0007193 | adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193) |
| 0.6 | 1.9 | GO:0042245 | RNA repair(GO:0042245) |
| 0.2 | 1.8 | GO:0051013 | microtubule severing(GO:0051013) |
| 0.0 | 1.7 | GO:0007019 | microtubule depolymerization(GO:0007019) |
| 0.1 | 1.6 | GO:0009313 | oligosaccharide catabolic process(GO:0009313) |
| 0.2 | 1.4 | GO:2001045 | negative regulation of integrin-mediated signaling pathway(GO:2001045) |
| 0.0 | 1.4 | GO:0051453 | regulation of intracellular pH(GO:0051453) |
| 0.0 | 1.4 | GO:0031102 | neuron projection regeneration(GO:0031102) |
| 0.0 | 1.4 | GO:0046839 | phospholipid dephosphorylation(GO:0046839) |
| 0.3 | 1.3 | GO:0030220 | platelet formation(GO:0030220) platelet morphogenesis(GO:0036344) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.3 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.0 | 1.5 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.0 | 1.5 | GO:0030173 | integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228) |
| 0.0 | 1.4 | GO:0030027 | lamellipodium(GO:0030027) |
| 0.0 | 1.3 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.1 | 1.2 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.1 | 1.1 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.1 | 1.1 | GO:0070822 | Sin3-type complex(GO:0070822) |
| 0.0 | 1.1 | GO:0030141 | secretory granule(GO:0030141) |
| 0.0 | 1.0 | GO:0032154 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.4 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.0 | 2.1 | GO:0008013 | beta-catenin binding(GO:0008013) |
| 0.5 | 1.9 | GO:0035516 | oxidative DNA demethylase activity(GO:0035516) DNA-N1-methyladenine dioxygenase activity(GO:0043734) RNA N6-methyladenosine dioxygenase activity(GO:1990931) |
| 0.0 | 1.9 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.2 | 1.8 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
| 0.0 | 1.8 | GO:0016616 | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0016616) |
| 0.1 | 1.6 | GO:0052796 | exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796) |
| 0.1 | 1.4 | GO:0072542 | phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542) |
| 0.1 | 1.3 | GO:0015385 | monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) |
| 0.1 | 1.3 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.9 | PID CONE PATHWAY | Visual signal transduction: Cones |
| 0.0 | 0.9 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.0 | 0.8 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.0 | 0.6 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.0 | 0.6 | PID CD8 TCR PATHWAY | TCR signaling in naïve CD8+ T cells |
| 0.0 | 0.5 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
| 0.0 | 0.5 | PID IFNG PATHWAY | IFN-gamma pathway |
| 0.0 | 0.5 | ST TUMOR NECROSIS FACTOR PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.0 | 0.5 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
| 0.0 | 0.5 | PID AP1 PATHWAY | AP-1 transcription factor network |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.5 | REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS | Genes involved in Post-translational modification: synthesis of GPI-anchored proteins |
| 0.1 | 1.3 | REACTOME HYALURONAN METABOLISM | Genes involved in Hyaluronan metabolism |
| 0.0 | 1.3 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.0 | 1.3 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.0 | 1.1 | REACTOME ASPARAGINE N LINKED GLYCOSYLATION | Genes involved in Asparagine N-linked glycosylation |
| 0.1 | 0.9 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.1 | 0.7 | REACTOME TRANSPORT OF ORGANIC ANIONS | Genes involved in Transport of organic anions |
| 0.0 | 0.7 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.1 | 0.6 | REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS | Genes involved in Phosphorylation of CD3 and TCR zeta chains |
| 0.0 | 0.6 | REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |