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PRJNA207719: Tissue specific transcriptome profiling

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Results for BX548005.1+smarcc2

Z-value: 2.10

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Transcription factors associated with BX548005.1+smarcc2

Gene Symbol Gene ID Gene Info
ENSDARG00000077946 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
ENSDARG00000110907 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
smarcc2dr11_v1_chr6_+_39836474_398364740.932.4e-02Click!

Activity profile of BX548005.1+smarcc2 motif

Sorted Z-values of BX548005.1+smarcc2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_65536095 1.87 ENSDART00000189898
si:dkey-21e5.1
chr10_+_36037977 1.79 ENSDART00000164678
katanin p60 subunit A-like 1
chr16_+_5774977 1.71 ENSDART00000134202
cholecystokinin a
chr8_-_5155545 1.39 ENSDART00000056885
dihydropyrimidinase like 2
chr16_-_34285106 1.38 ENSDART00000044235
phosphatase and actin regulator 4b
chr25_+_10458990 1.34 ENSDART00000130354
ENSDART00000044738
RIC8 guanine nucleotide exchange factor A
chr18_+_45792035 1.34 ENSDART00000135045
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr6_-_13449556 1.29 ENSDART00000184566
ENSDART00000112883
ENSDART00000185377
formin-like 2b
chr16_+_34523515 1.24 ENSDART00000041007
stathmin 1b
chr7_-_36358303 1.23 ENSDART00000130028
fat mass and obesity associated
chr8_-_21268303 1.22 ENSDART00000067211
G protein-coupled receptor 37 like 1b
chr9_-_29985390 1.17 ENSDART00000134157
interleukin 1 receptor accessory protein-like 1a
chr16_-_43971258 1.14 ENSDART00000141941
zinc finger protein, FOG family member 2a
chr1_+_16073887 1.09 ENSDART00000160270
tumor suppressor candidate 3
chr12_+_7445595 1.08 ENSDART00000103536
ENSDART00000152524
phytanoyl-CoA 2-hydroxylase interacting protein-like b
chr11_-_10770053 1.08 ENSDART00000179213
solute carrier family 4, sodium bicarbonate transporter, member 10a
chr21_-_43485351 1.00 ENSDART00000151597
ankyrin repeat domain 46a
chr16_+_34522977 0.99 ENSDART00000144069
progestin and adipoQ receptor family member VII, b
chr24_+_25692802 0.98 ENSDART00000190493
calcium/calmodulin-dependent protein kinase II inhibitor 2
chr6_+_58543336 0.94 ENSDART00000157018
stathmin-like 3
chr13_+_33055548 0.94 ENSDART00000137315
retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
chr19_-_5254699 0.94 ENSDART00000081951
syntaxin 1B
chr21_-_23746916 0.92 ENSDART00000017229
neural cell adhesion molecule 1a
chr20_-_40319890 0.92 ENSDART00000075112
clavesin 2
chr15_-_2857961 0.89 ENSDART00000033263
ankyrin repeat domain 49
chr8_-_39984593 0.86 ENSDART00000140127
aspartate beta-hydroxylase domain containing 2
chr16_-_34401412 0.85 ENSDART00000054020
human immunodeficiency virus type I enhancer binding protein 3b
chr25_-_5815834 0.85 ENSDART00000112853
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr25_+_7229046 0.85 ENSDART00000149965
ENSDART00000041820
leucine rich repeat and Ig domain containing 1a
chr25_+_15273370 0.85 ENSDART00000045659
t-complex 11, testis-specific-like 1
chr21_+_21791343 0.83 ENSDART00000151654
sialidase 3 (membrane sialidase), tandem duplicate 1
chr17_-_26604946 0.82 ENSDART00000087062
family with sequence similarity 149, member B1
chr8_+_18624658 0.80 ENSDART00000089141
fibronectin type III and SPRY domain containing 1
chr23_-_4019928 0.79 ENSDART00000021062
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr2_+_38608290 0.78 ENSDART00000159066
cadherin 24, type 2b
chr13_-_32626247 0.76 ENSDART00000100663
WD repeat domain 35
chr5_-_22082918 0.76 ENSDART00000020908
zinc finger, C4H2 domain containing
chr25_-_31763897 0.75 ENSDART00000041740
ubiquitin-like 7a (bone marrow stromal cell-derived)
chr1_-_54947592 0.75 ENSDART00000129710
cartilage acidic protein 1a
chr2_-_13254821 0.75 ENSDART00000022621
3-ketodihydrosphingosine reductase
chr17_-_21418340 0.74 ENSDART00000007021
ATPase, H+ transporting, lysosomal, V1 subunit B, member a
chr20_-_42100932 0.74 ENSDART00000191930
solute carrier family 35, member F1
chr2_+_53357953 0.73 ENSDART00000187577
cugbp, Elav-like family member 5b
chr21_+_21791799 0.72 ENSDART00000151759
sialidase 3 (membrane sialidase), tandem duplicate 1
chr19_-_1023051 0.72 ENSDART00000158429
transmembrane protein 42b
chr2_-_44720551 0.71 ENSDART00000146380
MAP6 domain containing 1
chr8_+_1148876 0.71 ENSDART00000148651
arginine vasopressin
chr4_-_27398385 0.71 ENSDART00000142117
ENSDART00000150553
ENSDART00000182746
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5a
chr17_-_8692722 0.70 ENSDART00000148931
ENSDART00000192891
C-terminal binding protein 2a
chr18_+_2189211 0.70 ENSDART00000170827
cell cycle progression 1
chr20_-_45661049 0.69 ENSDART00000124582
ENSDART00000131251
N-ethylmaleimide-sensitive factor attachment protein, beta b
chr5_-_23675222 0.69 ENSDART00000135153
si:dkey-110k5.6
chr22_-_38516922 0.68 ENSDART00000151257
ENSDART00000151785
kinesin light chain 4
chr4_+_11479705 0.68 ENSDART00000019458
ENSDART00000150587
ENSDART00000139370
ENSDART00000135826
ankyrin repeat and SOCS box containing 13a, tandem duplicate 1
chr12_+_48480632 0.67 ENSDART00000158157
Rho GTPase activating protein 44
chr4_-_5092335 0.67 ENSDART00000130453
adenosylhomocysteinase-like 2
chr6_-_27057702 0.67 ENSDART00000149363
serine/threonine kinase 25a
chr3_+_14339728 0.67 ENSDART00000184127
phospholipid phosphatase related 2a
chr17_+_25414033 0.66 ENSDART00000001691
L-threonine dehydrogenase 2
chr17_-_12336987 0.66 ENSDART00000172001
synaptosomal-associated protein, 25b
chr21_-_43065657 0.66 ENSDART00000180076
ENSDART00000190751
janus kinase and microtubule interacting protein 2
chr7_-_55292116 0.66 ENSDART00000122603
ring finger protein 166
chr15_-_14375452 0.65 ENSDART00000160675
ENSDART00000164028
ENSDART00000171642
D4, zinc and double PHD fingers family 1
chr8_+_21629941 0.65 ENSDART00000140145
adherens junctions associated protein 1
chr5_-_12407194 0.65 ENSDART00000125291
kinase suppressor of ras 2
chr17_-_945883 0.63 ENSDART00000158837
dynein, cytoplasmic 1, heavy chain 1
chr7_-_36358735 0.63 ENSDART00000188392
fat mass and obesity associated
chr6_+_48664275 0.62 ENSDART00000161184
si:dkey-238f9.1
chr5_-_41142467 0.62 ENSDART00000129415
zinc finger RNA binding protein
chr6_-_13188667 0.62 ENSDART00000191654
ADAM metallopeptidase domain 23a
chr25_+_3347461 0.62 ENSDART00000104888
solute carrier family 35, member B4
chr23_-_12158685 0.61 ENSDART00000135035
family with sequence similarity 217, member B
chr23_-_33654889 0.61 ENSDART00000146180
cysteine-serine-rich nuclear protein 2
chr21_-_30284404 0.60 ENSDART00000066363
zgc:175066
chr9_-_23217196 0.60 ENSDART00000083567
kinesin family member 5C
chr5_-_31716713 0.60 ENSDART00000131443
dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
chr10_-_37337579 0.59 ENSDART00000147705
oligodendrocyte myelin glycoprotein a
chr19_-_32150078 0.59 ENSDART00000134934
ENSDART00000186410
ENSDART00000181780
phosphoprotein membrane anchor with glycosphingolipid microdomains 1
chr16_-_30655980 0.58 ENSDART00000146508
low density lipoprotein receptor class A domain containing 4b
chr16_+_23495600 0.58 ENSDART00000021092
sorting nexin family member 27b
chr1_+_49878000 0.58 ENSDART00000047876
lymphoid enhancer-binding factor 1
chr14_-_30876708 0.58 ENSDART00000147597
ubiquitin-like 3b
chr20_+_38525567 0.58 ENSDART00000147787
zinc finger protein 512
chr25_-_8916913 0.58 ENSDART00000104629
ENSDART00000131748
furin (paired basic amino acid cleaving enzyme) b
chr8_-_40276035 0.57 ENSDART00000185301
ENSDART00000187610
ENSDART00000053158
ENSDART00000162020
lysine (K)-specific demethylase 2Ba
chr2_-_13254594 0.57 ENSDART00000155671
3-ketodihydrosphingosine reductase
chr17_-_16324565 0.57 ENSDART00000030835
homeobox containing 1a
chr5_-_41142768 0.56 ENSDART00000074789
zinc finger RNA binding protein
chr1_+_6172786 0.56 ENSDART00000126468
protein kinase, AMP-activated, gamma 3a non-catalytic subunit
chr17_-_24439672 0.56 ENSDART00000155020
WD repeat containing planar cell polarity effector
chr16_+_25137483 0.55 ENSDART00000155666
zinc finger protein 576, tandem duplicate 1
chr2_-_32352946 0.55 ENSDART00000144870
ENSDART00000077151
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1a
chr17_-_12764360 0.55 ENSDART00000003418
breast cancer metastasis-suppressor 1-like a
chr24_-_33276139 0.54 ENSDART00000128943
nuclear receptor binding protein 2b
chr14_+_45306073 0.54 ENSDART00000034606
ENSDART00000173301
sideroflexin 5b
chr13_-_49169545 0.54 ENSDART00000192076
translin-associated factor X
chr12_-_31103187 0.52 ENSDART00000005562
ENSDART00000031408
ENSDART00000125046
ENSDART00000009237
ENSDART00000122972
ENSDART00000153068
transcription factor 7 like 2
chr14_-_493029 0.52 ENSDART00000115093
zgc:172215
chr22_-_29689485 0.52 ENSDART00000182173
programmed cell death 4b
chr1_+_29281764 0.52 ENSDART00000112106
family with sequence similarity 155, member A
chr21_+_28496194 0.51 ENSDART00000138236
cytochrome c oxidase subunit VIIIA (ubiquitous)
chr6_-_53282572 0.51 ENSDART00000172615
ENSDART00000165036
RNA binding motif protein 5
chr11_-_23025949 0.51 ENSDART00000184859
ENSDART00000167818
ENSDART00000046122
ENSDART00000193120
ATPase plasma membrane Ca2+ transporting 2
chr19_+_177455 0.51 ENSDART00000111580
transmembrane protein 65
chr12_-_48467733 0.51 ENSDART00000153126
ENSDART00000152895
ENSDART00000014190
SEC31 homolog B, COPII coat complex component
chr14_-_30876299 0.51 ENSDART00000180305
ubiquitin-like 3b
chr13_+_11073282 0.50 ENSDART00000114911
ENSDART00000182462
ENSDART00000148100
ENSDART00000137816
ENSDART00000134888
ENSDART00000131320
serologically defined colon cancer antigen 8
chr17_+_9017775 0.49 ENSDART00000186901
ENSDART00000185407
A kinase (PRKA) anchor protein 6
chr24_+_15899365 0.49 ENSDART00000185965
neuropilin (NRP) and tolloid (TLL)-like 1, like
chr15_-_11341635 0.49 ENSDART00000055220
RAB30, member RAS oncogene family
chr11_-_18283886 0.48 ENSDART00000019248
STIM activating enhance
chr20_+_4060839 0.48 ENSDART00000178565
tripartite motif containing 67
chr23_-_4019699 0.48 ENSDART00000159780
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr15_+_15516612 0.48 ENSDART00000016024
tnf receptor-associated factor 4a
chr24_-_9960290 0.47 ENSDART00000143390
ENSDART00000092975
ENSDART00000184953
vacuolar protein sorting 41 homolog (S. cerevisiae)
chr25_-_20258508 0.47 ENSDART00000133860
ENSDART00000006840
ENSDART00000173434
dynamin 1-like
chr19_+_2546775 0.47 ENSDART00000148527
ENSDART00000097528
sp4 transcription factor
chr15_+_22867174 0.46 ENSDART00000035812
glutamate receptor, ionotropic, kainate 4
chr13_-_11072964 0.46 ENSDART00000135989
centrosomal protein 170Aa
chr7_-_29043075 0.46 ENSDART00000052342
THAP domain containing 11
chr22_+_22888 0.46 ENSDART00000082471
microfibril associated protein 2
chr3_+_23488652 0.45 ENSDART00000126282
nuclear receptor subfamily 1, group d, member 1
chr20_-_33790003 0.45 ENSDART00000020183
family with sequence similarity 102, member B, b
chr5_-_12687357 0.45 ENSDART00000193206
apoptosis-inducing factor, mitochondrion-associated, 3
chr7_+_20876303 0.45 ENSDART00000173495
ENSDART00000164172
GRB10 interacting GYF protein 1a
chr2_+_5841108 0.45 ENSDART00000136180
DIS3 like 3'-5' exoribonuclease 2
chr12_+_22680115 0.44 ENSDART00000152879
actin binding LIM protein family, member 2
chr15_-_9419472 0.44 ENSDART00000122117
sacsin molecular chaperone
chr22_+_10129788 0.44 ENSDART00000045752
TBC1 domain family, member 20
chr5_-_62988463 0.43 ENSDART00000047143
sperm antigen with calponin homology and coiled-coil domains 1
chr6_-_50730749 0.43 ENSDART00000157153
ENSDART00000110441
phosphatidylinositol glycan anchor biosynthesis, class U
chr2_-_52841762 0.42 ENSDART00000114682
ralA binding protein 1
chr11_+_37049347 0.42 ENSDART00000109235
bicaudal D homolog 2 (Drosophila)
chr25_+_18889332 0.42 ENSDART00000017043
cation/H+ exchanger protein 2
chr23_+_31405497 0.42 ENSDART00000053546
SH3 domain binding glutamate-rich protein like 2
chr4_+_25912654 0.41 ENSDART00000109508
ENSDART00000134218
vezatin, adherens junctions transmembrane protein
chr12_+_48390715 0.41 ENSDART00000149351
stearoyl-CoA desaturase (delta-9-desaturase)
chr15_+_21744680 0.41 ENSDART00000016860
protein phosphatase 2, regulatory subunit A, beta b
chr21_-_38031038 0.40 ENSDART00000179483
ENSDART00000076238
RNA binding motif protein 41
chr15_+_8767650 0.40 ENSDART00000033871
adaptor-related protein complex 2, sigma 1 subunit
chr24_+_19591893 0.40 ENSDART00000152026
solute carrier organic anion transporter family member 5A1a
chr11_+_8152872 0.40 ENSDART00000091638
ENSDART00000138057
ENSDART00000166379
sterile alpha motif domain containing 13
chr10_+_37182626 0.40 ENSDART00000137636
kinase suppressor of ras 1a
chr24_+_39576071 0.40 ENSDART00000147137
si:dkey-161j23.6
chr19_+_15521997 0.39 ENSDART00000003164
protein phosphatase 1, regulatory subunit 8a
chr20_-_16849306 0.39 ENSDART00000131395
ENSDART00000027582
breast cancer metastasis-suppressor 1-like b
chr10_+_21650828 0.39 ENSDART00000160754
protocadherin 1 gamma 1
chr24_+_25032340 0.39 ENSDART00000005845
myotubularin related protein 6
chr6_+_58522557 0.39 ENSDART00000128062
ADP-ribosylation factor related protein 1
chr8_+_16726386 0.39 ENSDART00000144621
small integral membrane protein 15
chr3_+_24060454 0.39 ENSDART00000143088
chromobox homolog 1a (HP1 beta homolog Drosophila)
chr16_-_27161410 0.39 ENSDART00000177503

chr5_-_26795438 0.39 ENSDART00000146124
si:ch211-102c2.7
chr18_-_27316599 0.39 ENSDART00000028294
zgc:56106
chr21_+_8427059 0.39 ENSDART00000143151
DENN/MADD domain containing 1A
chr17_-_26604549 0.39 ENSDART00000174773
family with sequence similarity 149, member B1
chr4_+_25912308 0.38 ENSDART00000167845
ENSDART00000136927
vezatin, adherens junctions transmembrane protein
chr6_-_16394528 0.38 ENSDART00000089445
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr9_-_23242684 0.38 ENSDART00000053282
ENSDART00000179770
cyclin T2a
chr6_-_10780698 0.38 ENSDART00000151714
G protein-coupled receptor 155b
chr4_+_15605844 0.37 ENSDART00000101619
ENSDART00000021384
exocyst complex component 4
chr16_-_41131578 0.37 ENSDART00000102649
ENSDART00000145956
protein tyrosine phosphatase, non-receptor type 23, a
chr11_+_23957440 0.36 ENSDART00000190721
contactin 2
chr13_-_15929402 0.36 ENSDART00000090273
tubulin tyrosine ligase
chr11_+_37049105 0.36 ENSDART00000155408
bicaudal D homolog 2 (Drosophila)
chr15_-_29556757 0.36 ENSDART00000060049
heat shock protein 70 family, member 13
chr10_+_8091144 0.35 ENSDART00000143848
ENSDART00000075485
SUB1 homolog, transcriptional regulator a
chr8_-_46321889 0.35 ENSDART00000075189
ENSDART00000122801
mechanistic target of rapamycin kinase
chr5_+_37379825 0.35 ENSDART00000171826
kelch-like family member 13
chr11_+_27133560 0.35 ENSDART00000158411
histone deacetylase 11
chr21_-_11054876 0.35 ENSDART00000146576
neural precursor cell expressed, developmentally down-regulated 4-like
chr19_+_40379771 0.35 ENSDART00000017917
ENSDART00000110699
VPS50 EARP/GARPII complex subunit
VPS50 EARP/GARPII complex subunit
chr16_-_2390931 0.34 ENSDART00000149463
HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
chr13_+_2617555 0.34 ENSDART00000162208
phospholipid phosphatase 4
chr1_-_22803147 0.33 ENSDART00000086867
transmembrane anterior posterior transformation 1b
chr5_+_41143563 0.33 ENSDART00000011229
SUB1 homolog, transcriptional regulator b
chr19_-_6083761 0.33 ENSDART00000151185
ENSDART00000143941
glycogen synthase kinase 3 alpha a
chr7_+_15618127 0.32 ENSDART00000080160
leucine rich repeat containing 28
chr7_+_74134010 0.32 ENSDART00000164874
claudin domain containing 1a
chr3_-_26904774 0.32 ENSDART00000103690
C-type lectin domain containing 16A
chr18_+_9641210 0.32 ENSDART00000182024
piccolo presynaptic cytomatrix protein b
chr6_+_4229360 0.32 ENSDART00000191347
ENSDART00000130642

chr11_-_44999858 0.31 ENSDART00000167759
ENSDART00000126845
LIM-domain binding 1b
chr23_-_14216506 0.31 ENSDART00000019620
DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
chr1_+_40237276 0.31 ENSDART00000037553
fatty acid amide hydrolase 2a
chr17_+_43659940 0.31 ENSDART00000145738
ENSDART00000075619
2-aminoethanethiol (cysteamine) dioxygenase b
chr8_-_31384607 0.31 ENSDART00000164134
ENSDART00000024872
cAMP responsive element binding protein 3-like 3 like
chr23_+_43668756 0.31 ENSDART00000112598
OTU deubiquitinase 4
chr22_-_20342260 0.30 ENSDART00000161610
ENSDART00000165667
transcription factor 3b
chr5_-_22019061 0.30 ENSDART00000113066
APC membrane recruitment protein 1
chr25_-_21716326 0.30 ENSDART00000152011
si:dkey-81e3.1
chr4_+_11483335 0.30 ENSDART00000184978
ENSDART00000140954
ankyrin repeat and SOCS box containing 13a, tandem duplicate 2
chr19_+_18627100 0.30 ENSDART00000167245
vacuolar protein sorting 52 homolog (S. cerevisiae)
chr16_+_25107344 0.29 ENSDART00000033211
zgc:66448
chr2_-_1468258 0.29 ENSDART00000114431
glycosylphosphatidylinositol anchor attachment 1
chr24_+_15897717 0.29 ENSDART00000105956
neuropilin (NRP) and tolloid (TLL)-like 1, like
chr25_-_4733008 0.29 ENSDART00000191884
dopamine receptor D4a
chr19_-_17385548 0.28 ENSDART00000162383
NFKB inhibitor interacting Ras-like 1
chr8_-_36618073 0.28 ENSDART00000047912
G patch domain and KOW motifs
chr1_+_52130213 0.28 ENSDART00000018817
ring finger protein 11a

Network of associatons between targets according to the STRING database.

First level regulatory network of BX548005.1+smarcc2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0042245 RNA repair(GO:0042245)
0.3 1.3 GO:0030220 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.3 0.9 GO:0021961 posterior commissure morphogenesis(GO:0021961)
0.2 1.8 GO:0051013 microtubule severing(GO:0051013)
0.2 1.4 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.2 0.9 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.2 0.7 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.2 0.5 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.2 0.5 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 1.3 GO:0015886 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.1 0.5 GO:0010226 response to lithium ion(GO:0010226)
0.1 1.6 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.1 0.4 GO:0048677 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.1 0.7 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.6 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 0.5 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 0.6 GO:0060784 regulation of cell proliferation involved in tissue homeostasis(GO:0060784)
0.1 0.3 GO:2000378 negative regulation of reactive oxygen species metabolic process(GO:2000378)
0.1 0.3 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.1 0.4 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1 0.7 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.1 0.7 GO:2001106 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.5 GO:1903146 regulation of mitophagy(GO:1903146)
0.1 0.3 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.4 GO:0010586 miRNA metabolic process(GO:0010586)
0.1 0.6 GO:0098971 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.1 0.6 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 0.7 GO:0006566 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.1 0.2 GO:1903358 regulation of Golgi organization(GO:1903358)
0.1 0.2 GO:0009838 abscission(GO:0009838) mitotic cytokinesis checkpoint(GO:0044878)
0.1 0.8 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.1 0.3 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 1.2 GO:0045920 negative regulation of exocytosis(GO:0045920)
0.1 0.8 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.1 0.6 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.1 0.5 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.7 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.1 1.1 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.5 GO:0046959 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.1 0.5 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.2 GO:0034969 histone arginine methylation(GO:0034969)
0.1 0.5 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.1 0.2 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.1 1.1 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.7 GO:0045161 neuronal ion channel clustering(GO:0045161) clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.3 GO:1901096 regulation of autophagosome maturation(GO:1901096)
0.0 0.3 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.0 0.2 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.0 0.5 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.2 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 2.8 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.7 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.8 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.3 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.0 0.6 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.3 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.3 GO:0033182 regulation of histone ubiquitination(GO:0033182)
0.0 1.7 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.1 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.2 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 0.5 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 1.4 GO:0051453 regulation of intracellular pH(GO:0051453)
0.0 0.1 GO:0055091 phospholipid homeostasis(GO:0055091)
0.0 0.3 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.0 0.1 GO:0048313 organelle inheritance(GO:0048308) Golgi inheritance(GO:0048313)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.8 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.0 1.4 GO:0031102 neuron projection regeneration(GO:0031102)
0.0 0.3 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.1 GO:0060547 negative regulation of necroptotic process(GO:0060546) negative regulation of necrotic cell death(GO:0060547)
0.0 0.9 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.4 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.4 GO:0006903 vesicle targeting(GO:0006903)
0.0 1.0 GO:0032456 endocytic recycling(GO:0032456)
0.0 1.0 GO:0007586 digestion(GO:0007586)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.6 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.5 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.1 GO:0030576 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576) protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) protein localization to nucleoplasm(GO:1990173)
0.0 0.8 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.1 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.8 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.8 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.2 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.0 0.4 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.7 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 1.3 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 1.1 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.5 GO:0003171 atrioventricular valve development(GO:0003171)
0.0 0.4 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 1.4 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.3 GO:0042026 protein refolding(GO:0042026)
0.0 0.6 GO:0006482 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0 0.1 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 1.2 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.7 GO:0008643 carbohydrate transport(GO:0008643)
0.0 0.6 GO:0034111 negative regulation of homotypic cell-cell adhesion(GO:0034111) negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038)
0.0 0.1 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.5 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.6 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.4 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 0.0 GO:0006499 N-terminal protein myristoylation(GO:0006499) N-terminal peptidyl-glycine N-myristoylation(GO:0018008) protein myristoylation(GO:0018377)
0.0 0.3 GO:0016114 terpenoid biosynthetic process(GO:0016114)
0.0 0.2 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.1 GO:0046548 retinal rod cell development(GO:0046548)
0.0 1.0 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.0 0.4 GO:0035305 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0 0.3 GO:0038034 signal transduction in absence of ligand(GO:0038034) extrinsic apoptotic signaling pathway in absence of ligand(GO:0097192)
0.0 0.1 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.0 0.3 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.0 GO:0006565 L-serine catabolic process(GO:0006565) glycine biosynthetic process from serine(GO:0019264)
0.0 0.0 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.0 0.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:0060612 adipose tissue development(GO:0060612)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.2 0.6 GO:0097541 axonemal basal plate(GO:0097541)
0.2 0.7 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.2 0.7 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.1 0.5 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.1 0.7 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 0.5 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 0.3 GO:1990745 EARP complex(GO:1990745)
0.1 0.7 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 0.8 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 0.4 GO:0032584 growth cone membrane(GO:0032584)
0.1 0.2 GO:0090443 FAR/SIN/STRIPAK complex(GO:0090443)
0.1 1.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.2 GO:0031417 NatC complex(GO:0031417)
0.1 0.5 GO:0030897 HOPS complex(GO:0030897)
0.1 1.2 GO:0005801 cis-Golgi network(GO:0005801)
0.1 0.3 GO:0000938 GARP complex(GO:0000938)
0.1 0.2 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.1 1.1 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.6 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.4 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.7 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.4 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0 0.4 GO:0032021 NELF complex(GO:0032021)
0.0 0.4 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.9 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.8 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.3 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.0 0.4 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 0.6 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.3 GO:0098982 GABA-ergic synapse(GO:0098982)
0.0 0.1 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.0 0.4 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 1.5 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.0 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.5 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.7 GO:0071565 nBAF complex(GO:0071565)
0.0 0.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.5 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.3 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 1.5 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 2.3 GO:0016607 nuclear speck(GO:0016607)
0.0 0.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 1.3 GO:0005871 kinesin complex(GO:0005871)
0.0 0.6 GO:0030286 dynein complex(GO:0030286)
0.0 0.2 GO:0030315 T-tubule(GO:0030315)
0.0 1.4 GO:0030027 lamellipodium(GO:0030027)
0.0 0.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.1 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.1 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 0.0 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.1 GO:0030141 secretory granule(GO:0030141)
0.0 0.6 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.1 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.1 GO:0015030 Cajal body(GO:0015030)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0035516 oxidative DNA demethylase activity(GO:0035516) DNA-N1-methyladenine dioxygenase activity(GO:0043734) RNA N6-methyladenosine dioxygenase activity(GO:1990931)
0.4 1.2 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
0.2 1.0 GO:0010858 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.2 1.8 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 1.6 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1 0.7 GO:0008743 L-threonine 3-dehydrogenase activity(GO:0008743)
0.1 0.6 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.1 0.6 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.5 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.7 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 1.3 GO:0015385 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 0.4 GO:0015369 calcium:proton antiporter activity(GO:0015369) metal ion:proton antiporter activity(GO:0051139)
0.1 1.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.4 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.1 0.4 GO:0030626 U12 snRNA binding(GO:0030626)
0.1 0.5 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.1 0.3 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.1 0.7 GO:0034452 dynactin binding(GO:0034452)
0.1 1.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 1.4 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.1 0.6 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.2 GO:0101006 inorganic diphosphatase activity(GO:0004427) protein histidine phosphatase activity(GO:0101006)
0.1 2.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 0.6 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.1 0.2 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.1 0.8 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.3 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.2 GO:0008469 histone-arginine N-methyltransferase activity(GO:0008469)
0.0 0.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.9 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 2.1 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.8 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.0 0.5 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 1.0 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0008169 C-methyltransferase activity(GO:0008169)
0.0 0.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.9 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.2 GO:0046625 sphingolipid binding(GO:0046625) ceramide binding(GO:0097001)
0.0 0.4 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.4 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.2 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 1.9 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 0.4 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.1 GO:0032183 SUMO binding(GO:0032183)
0.0 1.3 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.1 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 1.1 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.1 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.0 1.0 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.6 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0070888 E-box binding(GO:0070888)
0.0 0.4 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 1.2 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.6 GO:0016208 AMP binding(GO:0016208)
0.0 0.1 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0008263 mismatch base pair DNA N-glycosylase activity(GO:0000700) pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.0 0.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.3 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 0.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.8 GO:0017022 myosin binding(GO:0017022)
0.0 0.3 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.3 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.2 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.0 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379)
0.0 0.7 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.4 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 1.8 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0016616)
0.0 0.3 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 0.0 GO:0070905 glycine hydroxymethyltransferase activity(GO:0004372) serine binding(GO:0070905)
0.0 0.0 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263) beta-1,3-galactosyltransferase activity(GO:0048531)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.9 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.3 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.5 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.5 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.5 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.6 PID AURORA B PATHWAY Aurora B signaling
0.0 0.5 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.8 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.6 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.1 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.5 PID AP1 PATHWAY AP-1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 0.7 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 0.6 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 0.9 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 1.5 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 1.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.6 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.7 REACTOME KINESINS Genes involved in Kinesins
0.0 0.3 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.5 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.5 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.3 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.6 REACTOME APOPTOTIC EXECUTION PHASE Genes involved in Apoptotic execution phase
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.6 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.6 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.2 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.3 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.5 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.1 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.0 0.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.5 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions