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PRJNA195909:zebrafish embryo and larva development
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Results for znf711
Z-value: 2.19
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Transcription factors associated with znf711
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| znf711 | dr11_v1_chr14_-_12020653_12020653 | 0.86 | 2.6e-03 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr19_-_27830818 Show fit | 3.11 |
ENSDART00000131767
|
PAP associated domain containing 7 |
|
| chr20_-_43742822 Show fit | 3.04 |
ENSDART00000181729
|
si:dkeyp-50f7.2 |
|
| chr23_+_35650771 Show fit | 2.96 |
ENSDART00000005158
|
cyclin T1 |
|
| chr17_+_654759 Show fit | 2.95 |
ENSDART00000193703
|
|
|
| chr19_+_31585917 Show fit | 2.89 |
ENSDART00000132182
|
geminin, DNA replication inhibitor |
|
| chr20_+_1329509 Show fit | 2.74 |
ENSDART00000017791
ENSDART00000136669 |
TGF-beta activated kinase 1/MAP3K7 binding protein 2 |
|
| chr3_+_18807524 Show fit | 2.67 |
ENSDART00000055757
|
transportin 2 (importin 3, karyopherin beta 2b) |
|
| chr19_+_31585341 Show fit | 2.65 |
ENSDART00000052185
|
geminin, DNA replication inhibitor |
|
| chr8_+_52377516 Show fit | 2.52 |
ENSDART00000115398
|
AT rich interactive domain 5A (MRF1-like) |
|
| chr5_+_55984270 Show fit | 2.48 |
ENSDART00000047358
ENSDART00000138191 |
FK506 binding protein 6 |
Network of associatons between targets according to the STRING database.
First level regulatory network of znf711
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 6.8 | GO:0008156 | negative regulation of DNA replication(GO:0008156) |
| 0.2 | 5.6 | GO:0043966 | histone H3 acetylation(GO:0043966) |
| 0.1 | 5.6 | GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123) |
| 0.1 | 4.9 | GO:0006606 | protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593) |
| 0.0 | 3.7 | GO:0016579 | protein deubiquitination(GO:0016579) |
| 0.2 | 3.2 | GO:0043687 | post-translational protein modification(GO:0043687) |
| 0.1 | 3.0 | GO:0032786 | positive regulation of DNA-templated transcription, elongation(GO:0032786) |
| 0.0 | 2.8 | GO:0018105 | peptidyl-serine phosphorylation(GO:0018105) |
| 0.2 | 2.7 | GO:0035090 | maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199) |
| 0.2 | 2.5 | GO:0034587 | piRNA metabolic process(GO:0034587) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 6.9 | GO:0005730 | nucleolus(GO:0005730) |
| 0.1 | 4.8 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.0 | 4.0 | GO:0000786 | nucleosome(GO:0000786) |
| 0.3 | 3.0 | GO:0019908 | cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908) |
| 0.2 | 2.8 | GO:0070775 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
| 0.0 | 2.3 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 0.0 | 2.2 | GO:0030027 | lamellipodium(GO:0030027) |
| 0.1 | 2.1 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.5 | 1.9 | GO:0098890 | extrinsic component of postsynaptic membrane(GO:0098890) |
| 0.5 | 1.8 | GO:0044326 | dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 10.5 | GO:0004674 | protein serine/threonine kinase activity(GO:0004674) |
| 0.2 | 5.1 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.1 | 4.0 | GO:0004402 | histone acetyltransferase activity(GO:0004402) |
| 0.0 | 3.8 | GO:0101005 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005) |
| 0.1 | 3.5 | GO:0042826 | histone deacetylase binding(GO:0042826) |
| 0.0 | 3.4 | GO:0005085 | guanyl-nucleotide exchange factor activity(GO:0005085) |
| 0.1 | 3.2 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
| 0.2 | 3.1 | GO:0070530 | K63-linked polyubiquitin binding(GO:0070530) |
| 0.1 | 2.9 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
| 0.1 | 2.8 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 5.0 | PID WNT NONCANONICAL PATHWAY | Noncanonical Wnt signaling pathway |
| 0.4 | 2.8 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
| 0.1 | 2.7 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.0 | 2.4 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.0 | 2.2 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.1 | 2.1 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 0.0 | 1.8 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.0 | 1.4 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.1 | 1.0 | PID IL23 PATHWAY | IL23-mediated signaling events |
| 0.1 | 1.0 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 5.6 | REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION | Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation |
| 0.4 | 5.6 | REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX | Genes involved in Association of licensing factors with the pre-replicative complex |
| 0.1 | 3.8 | REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
| 0.1 | 3.6 | REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |
| 0.3 | 2.7 | REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
| 0.1 | 2.5 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.1 | 2.4 | REACTOME DESTABILIZATION OF MRNA BY KSRP | Genes involved in Destabilization of mRNA by KSRP |
| 0.1 | 2.4 | REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS | Genes involved in Transport of Ribonucleoproteins into the Host Nucleus |
| 0.2 | 2.3 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.1 | 2.0 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |