ISMARA results: zeb1a+zeb1b

Project

PRJNA195909:zebrafish embryo and larva development

Navigation

Downloads

Results for zeb1a+zeb1b

Z-value: 1.23

Motif logo

Transcription factors associated with zeb1a+zeb1b

Gene Symbol	Gene ID	Gene Info
zeb1b NCBI UniProt	ENSDARG00000013207	zinc finger E-box binding homeobox 1b
zeb1a NCBI UniProt	ENSDARG00000016788	zinc finger E-box binding homeobox 1a
zeb1b NCBI UniProt	ENSDARG00000113922	zinc finger E-box binding homeobox 1b

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
zeb1a	dr11_v1_chr2_-_43850897_43850897	0.78	1.4e-02	Click!
zeb1b	dr11_v1_chr12_-_26851726_26851726	-0.39	3.0e-01	Click!

Activity profile of zeb1a+zeb1b motif

Sorted Z-values of zeb1a+zeb1b motif

Top targets:

Search:

Show entries

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr7_-_55648336 Show fit	1.88	ENSDART00000147792 ENSDART00000135304 ENSDART00000131923	pabpn1l NCBI UniProt Show fit	poly(A) binding protein, nuclear 1-like (cytoplasmic)
chr21_-_30293224 Show fit	1.36	ENSDART00000101051	slbp2 NCBI UniProt Show fit	stem-loop binding protein 2
chr24_+_12835935 Show fit	1.36	ENSDART00000114762	nanog NCBI UniProt Show fit	nanog homeobox
chr17_-_2596125 Show fit	1.35	ENSDART00000175740	zp3.2 NCBI UniProt Show fit	zona pellucida glycoprotein 3, tandem duplicate 2
chr15_-_1590858 Show fit	1.33	ENSDART00000081875	nnr NCBI UniProt Show fit	nanor
chr5_+_22974019 Show fit	1.21	ENSDART00000147157 ENSDART00000020434	brwd3 NCBI UniProt Show fit	bromodomain and WD repeat domain containing 3
chr5_-_67799617 Show fit	1.12	ENSDART00000192117	eif4e1b NCBI UniProt Show fit	eukaryotic translation initiation factor 4E family member 1B
chr22_+_1170294 Show fit	1.11	ENSDART00000159761 ENSDART00000169809	irf6 NCBI UniProt Show fit	interferon regulatory factor 6
chr9_-_32912638 Show fit	1.09	ENSDART00000110582	fam160a2 NCBI UniProt Show fit	family with sequence similarity 160, member A2
chr1_+_24387659 Show fit	1.06	ENSDART00000130356	qdprb2 NCBI UniProt Show fit	quinoid dihydropteridine reductase b2

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of zeb1a+zeb1b

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	5.4	GO:0035803	binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.0	2.4	GO:0090630	activation of GTPase activity(GO:0090630)
0.3	1.9	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1	1.6	GO:0016925	protein sumoylation(GO:0016925)
0.0	1.6	GO:0006367	transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0	1.6	GO:0016573	histone acetylation(GO:0016573)
0.1	1.5	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1	1.5	GO:0006491	N-glycan processing(GO:0006491)
0.1	1.5	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.1	1.4	GO:0060968	regulation of gene silencing(GO:0060968)

Showing 1 to 10 of 392 entries

Gene overrepresentation in cellular component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	5.0	GO:0005730	nucleolus(GO:0005730)
0.0	3.3	GO:0043296	apical junction complex(GO:0043296)
0.1	2.1	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.1	2.0	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	2.0	GO:0055037	recycling endosome(GO:0055037)
0.0	1.9	GO:0016459	myosin complex(GO:0016459)
0.1	1.6	GO:0043186	P granule(GO:0043186)
0.1	1.5	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	1.5	GO:0005814	centriole(GO:0005814)
0.0	1.5	GO:0000123	histone acetyltransferase complex(GO:0000123)

Showing 1 to 10 of 141 entries

Gene overrepresentation in molecular function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	5.0	GO:0035804	structural constituent of egg coat(GO:0035804)
0.0	2.3	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
0.0	2.2	GO:0003774	motor activity(GO:0003774)
0.0	2.2	GO:0003729	mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1	1.9	GO:0003688	DNA replication origin binding(GO:0003688)
0.1	1.8	GO:0070697	activin receptor binding(GO:0070697)
0.1	1.6	GO:0036002	pre-mRNA binding(GO:0036002)
0.4	1.5	GO:0004155	6,7-dihydropteridine reductase activity(GO:0004155) NADH binding(GO:0070404)
0.0	1.5	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.0	1.5	GO:0004527	exonuclease activity(GO:0004527)

Showing 1 to 10 of 264 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.1	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.1	1.7	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	1.6	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	1.5	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	1.4	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.1	1.2	PID RHOA PATHWAY	RhoA signaling pathway
0.0	1.0	PID AURORA B PATHWAY	Aurora B signaling
0.0	0.8	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	0.8	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.0	0.7	PID RAC1 REG PATHWAY	Regulation of RAC1 activity

Showing 1 to 10 of 44 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.1	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	2.0	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	1.7	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.1	1.6	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.4	1.2	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	1.2	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.2	1.1	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.1	1.1	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.0	1.1	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.9	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions

Showing 1 to 10 of 87 entries

Results for zeb1a+zeb1b

Z-value: 1.23

Motif logo

Transcription factors associated with zeb1a+zeb1b

Activity-expression correlation:

Activity profile of zeb1a+zeb1b motif

Sorted Z-values of zeb1a+zeb1b motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of zeb1a+zeb1b

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: