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PRJNA195909:zebrafish embryo and larva development

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Results for zbtb49

Z-value: 0.48

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Transcription factors associated with zbtb49

Gene Symbol Gene ID Gene Info
zbtb49
ENSDARG00000102111 zinc finger and BTB domain containing 49

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
zbtb49dr11_v1_chr14_-_30050_30050-0.684.6e-02Click!

Activity profile of zbtb49 motif

Sorted Z-values of zbtb49 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr20_-_10120442 1.46 ENSDART00000144970
meis2b
Meis homeobox 2b
chr18_-_44129151 1.16 ENSDART00000087339
cdon
cell adhesion associated, oncogene regulated
chr24_-_3419998 1.03 ENSDART00000066839
slc35g2b
solute carrier family 35, member G2b
chr1_-_38709551 1.01 ENSDART00000128794
gpm6ab
glycoprotein M6Ab
chr11_+_8565323 0.96 ENSDART00000081607
ENSDART00000141612
tbl1xr1a
transducin (beta)-like 1 X-linked receptor 1a
chr7_+_22823889 0.90 ENSDART00000127467
ENSDART00000148576
ENSDART00000149993
pygmb
phosphorylase, glycogen, muscle b
chr11_+_8565828 0.86 ENSDART00000126523
tbl1xr1a
transducin (beta)-like 1 X-linked receptor 1a
chr8_-_38477817 0.60 ENSDART00000075989
inpp5l
inositol polyphosphate-5-phosphatase L
chr8_+_25302172 0.50 ENSDART00000046182
ENSDART00000145316
gstm.3
glutathione S-transferase mu tandem duplicate 3
chr14_+_33882973 0.49 ENSDART00000019396
clic2
chloride intracellular channel 2
chr9_+_8942258 0.49 ENSDART00000138836
ankrd10b
ankyrin repeat domain 10b
chr7_-_38340674 0.46 ENSDART00000075782
slc7a10a
solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10a
chr7_-_5148388 0.44 ENSDART00000143549
si:ch211-272h9.5
si:ch211-272h9.5
chr17_+_8925232 0.43 ENSDART00000036668
psmc1a
proteasome 26S subunit, ATPase 1a
chr9_+_14152211 0.40 ENSDART00000148055
si:ch211-67e16.11
si:ch211-67e16.11
chr9_+_38629962 0.32 ENSDART00000184890
znf148
zinc finger protein 148
chr10_-_15919839 0.28 ENSDART00000065032
pip5k1ba
phosphatidylinositol-4-phosphate 5-kinase, type I, beta a
chr13_+_51853716 0.20 ENSDART00000175341
ENSDART00000187855
LT631684.1

chr7_-_31941670 0.20 ENSDART00000180929
ENSDART00000075389
bdnf
brain-derived neurotrophic factor
chr21_+_25181003 0.19 ENSDART00000169700
si:dkey-183i3.9
si:dkey-183i3.9
chr7_-_44794322 0.13 ENSDART00000019270
nae1
nedd8 activating enzyme E1 subunit 1
chr6_+_36878815 0.13 ENSDART00000192482
traf3ip2l
TRAF3 interacting protein 2-like
chr22_+_12798569 0.13 ENSDART00000005720
stat1a
signal transducer and activator of transcription 1a
chr14_-_17622080 0.11 ENSDART00000112149
si:ch211-159i8.4
si:ch211-159i8.4
chr7_-_52334840 0.11 ENSDART00000174173
CR938716.1

chr21_-_22673758 0.08 ENSDART00000164910
gig2i
grass carp reovirus (GCRV)-induced gene 2i
chr22_-_8455462 0.04 ENSDART00000185238
CABZ01061508.1

chr14_+_9581896 0.02 ENSDART00000114563
tmem129
transmembrane protein 129, E3 ubiquitin protein ligase
chr7_-_31941330 0.01 ENSDART00000144682
bdnf
brain-derived neurotrophic factor

Network of associatons between targets according to the STRING database.

First level regulatory network of zbtb49

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0052576 carbohydrate localization(GO:0052575) carbohydrate storage(GO:0052576)
0.2 0.5 GO:0042940 D-amino acid transport(GO:0042940) D-alanine transport(GO:0042941) D-serine transport(GO:0042942)
0.1 1.5 GO:0003209 cardiac atrium morphogenesis(GO:0003209)
0.1 1.2 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 1.0 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.6 GO:0048016 inositol phosphate-mediated signaling(GO:0048016)
0.0 1.8 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.5 GO:0006749 glutathione metabolic process(GO:0006749)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.4 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 1.8 GO:0000118 histone deacetylase complex(GO:0000118)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0008184 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.1 0.4 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 0.6 GO:0052659 inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.2 GO:0005163 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.0 0.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 1.8 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.5 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 REACTOME MYOGENESIS Genes involved in Myogenesis