Project

PRJNA195909:zebrafish embryo and larva development

Navigation
Downloads

Results for zbtb3

Z-value: 1.79

Motif logo

Transcription factors associated with zbtb3

Gene Symbol Gene ID Gene Info
ENSDARG00000036235 zinc finger and BTB domain containing 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
zbtb3dr11_v1_chr14_+_35405518_35405518-0.958.3e-05Click!

Activity profile of zbtb3 motif

Sorted Z-values of zbtb3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_52398205 48.12 ENSDART00000143225
si:ch211-217k17.9
chr1_+_50921266 3.79 ENSDART00000006538
orthodenticle homeobox 2a
chr9_+_3429662 2.95 ENSDART00000160977
ENSDART00000114168
ENSDART00000082153

integrin, alpha 6a
chr3_-_61185746 2.84 ENSDART00000028219
parvalbumin 4
chr7_-_35432901 2.80 ENSDART00000026712
matrix metallopeptidase 2
chr7_-_25895189 2.74 ENSDART00000173599
ENSDART00000079235
ENSDART00000173786
ENSDART00000173602
ENSDART00000079245
ENSDART00000187568
ENSDART00000173505
CD99 molecule-like 2
chr11_+_10548171 2.60 ENSDART00000191497
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5a
chr14_+_6546516 2.59 ENSDART00000097214
ADAM metallopeptidase domain 19b
chr12_+_48220584 2.58 ENSDART00000164392
leucine rich repeat containing 20
chr16_+_10422836 2.41 ENSDART00000161568
INO80 complex subunit E
chr7_-_26087807 2.38 ENSDART00000052989
acetylcholinesterase
chr13_-_37127970 2.37 ENSDART00000135510
spectrin repeat containing, nuclear envelope 2b
chr15_-_2640966 2.27 ENSDART00000063320
claudin e
chr15_-_2632891 1.95 ENSDART00000081840
claudin j
chr6_+_13039951 1.94 ENSDART00000091700
ciliogenesis associated TTC17 interacting protein
chr8_-_54304381 1.93 ENSDART00000184177
rhodopsin
chr3_+_24458899 1.81 ENSDART00000156655
chromobox homolog 6b
chr20_+_25340814 1.75 ENSDART00000063028
connective tissue growth factor a
chr9_-_32753535 1.75 ENSDART00000060006
oligodendrocyte lineage transcription factor 2
chr9_+_307863 1.72 ENSDART00000163474
SH3 and cysteine rich domain 3
chr25_+_25453221 1.67 ENSDART00000176822
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7a
chr8_+_26293673 1.60 ENSDART00000144977
monoglyceride lipase
chr14_-_32258759 1.52 ENSDART00000052949
fibroblast growth factor 13a
chr2_+_68789 1.48 ENSDART00000058569
claudin 1
chr25_-_33275666 1.45 ENSDART00000193605

chr10_-_43294933 1.42 ENSDART00000062631
hyaluronan and proteoglycan link protein 1b
chr2_+_45643122 1.32 ENSDART00000138179
fibronectin type III domain containing 7, related sequence 4
chr24_+_6107901 1.31 ENSDART00000156419
si:ch211-37e10.2
chr7_+_34492744 1.31 ENSDART00000109635
ENSDART00000173844
calmodulin-like 4a
chr22_-_29336268 1.31 ENSDART00000132776
ENSDART00000186351
ENSDART00000121599
platelet-derived growth factor beta polypeptide a
chr16_-_32013913 1.30 ENSDART00000030282
ENSDART00000138701
glutathione S-transferase kappa 1
chr4_-_68913650 1.25 ENSDART00000184297
si:dkey-264f17.5
chr10_+_31951338 1.24 ENSDART00000019416
LHFPL tetraspan subfamily member 6
chr19_-_48010490 1.15 ENSDART00000159938
zgc:158376
chr24_-_24146875 1.15 ENSDART00000173052
MAP7 domain containing 2b
chr24_-_26383978 1.10 ENSDART00000031426
SKI-like proto-oncogene b
chr16_-_24598042 1.08 ENSDART00000156407
ENSDART00000154072
si:dkey-56f14.4
chr1_-_633356 1.04 ENSDART00000171019
amyloid beta (A4) precursor protein a
chr13_-_2215213 0.97 ENSDART00000129773
muscular LMNA-interacting protein
chr24_+_12740848 0.96 ENSDART00000060825
si:ch211-196f5.2
chr23_+_39558508 0.94 ENSDART00000017902
calcium/calmodulin-dependent protein kinase IGb
chr2_+_5621529 0.92 ENSDART00000144187
fibroblast growth factor 12a
chr3_+_24458204 0.92 ENSDART00000155028
ENSDART00000153551
chromobox homolog 6b
chr10_-_4375190 0.89 ENSDART00000016102

chr6_-_51556308 0.84 ENSDART00000149033
retinoblastoma-like 1 (p107)
chr25_+_13662606 0.83 ENSDART00000008989
coiled-coil domain containing 113
chr23_-_32404022 0.81 ENSDART00000156387
ENSDART00000155508
si:ch211-66i15.4
chr6_+_7507390 0.79 ENSDART00000149285
erb-b2 receptor tyrosine kinase 3a
chr1_+_44814322 0.74 ENSDART00000059227
NADH dehydrogenase (ubiquinone) Fe-S protein 8a
chr22_-_11136625 0.73 ENSDART00000016873
ENSDART00000125561
ATPase H+ transporting accessory protein 2
chr8_-_53488832 0.71 ENSDART00000191801
choline dehydrogenase
chr5_-_20446082 0.71 ENSDART00000051607
si:ch211-191d15.2
chr25_-_35542739 0.68 ENSDART00000097651
si:ch211-87j1.4
chr2_-_985417 0.66 ENSDART00000140540
si:ch211-241e1.3
chr9_+_21148318 0.63 ENSDART00000035428
hydroxyacid oxidase 2 (long chain)
chr4_+_12966640 0.62 ENSDART00000113357
von Hippel-Lindau tumor suppressor like
chr13_+_23282549 0.59 ENSDART00000101134
KH domain containing, RNA binding, signal transduction associated 2
chr6_-_38419318 0.57 ENSDART00000138026
gamma-aminobutyric acid (GABA) A receptor, alpha 5
chr12_-_35885349 0.57 ENSDART00000085662
centrosomal protein 131
chr19_+_25478203 0.56 ENSDART00000132934
collagen, type XXVIII, alpha 1a
chr20_+_38671894 0.56 ENSDART00000146544
MpV17 mitochondrial inner membrane protein
chr16_+_13898399 0.55 ENSDART00000140946
si:ch211-149k23.9
chr12_+_48683208 0.55 ENSDART00000188582
matrix metallopeptidase 21
chr19_+_917852 0.54 ENSDART00000082466
transforming growth factor beta receptor 2a
chr2_+_31454562 0.52 ENSDART00000136360
si:dkey-32m20.1
chr1_+_59007536 0.51 ENSDART00000165339
cell division cycle 37
chr16_+_4695075 0.51 ENSDART00000039054
mitochondrial trans-2-enoyl-CoA reductase
chr15_-_576135 0.49 ENSDART00000124170
cerebellin 20
chr3_+_61185660 0.49 ENSDART00000167114

chr7_-_57949117 0.47 ENSDART00000138803
ankyrin 2b, neuronal
chr8_+_22405477 0.44 ENSDART00000148267
si:dkey-23c22.7
chr15_-_12113045 0.44 ENSDART00000159879
Down syndrome cell adhesion molecule like 1
chr16_-_14552199 0.44 ENSDART00000133368
si:dkey-237j11.3
chr15_-_19705707 0.41 ENSDART00000047643
synaptotagmin-like 2b
chr22_-_8353386 0.38 ENSDART00000077600

chr23_-_7674902 0.38 ENSDART00000185612
ENSDART00000180524
pleiomorphic adenoma gene-like 2
chr21_+_35296246 0.38 ENSDART00000076750
interleukin 12B, b
chr8_+_22404981 0.37 ENSDART00000185211
ENSDART00000099972
si:dkey-23c22.7
si:dkey-23c22.9
chr14_+_24935131 0.36 ENSDART00000170871
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr11_-_36156935 0.35 ENSDART00000124935
ENSDART00000138609
BRICK1, SCAR/WAVE actin-nucleating complex subunit
glutathione peroxidase 1a
chr7_-_6592142 0.34 ENSDART00000160137
potassium inwardly-rectifying channel, subfamily J, member 10a
chr11_+_1805421 0.34 ENSDART00000173143
low density lipoprotein receptor-related protein 1Aa
chr22_-_25469751 0.32 ENSDART00000171670

chr22_-_25502977 0.32 ENSDART00000181749

chr1_-_22687913 0.31 ENSDART00000168171
fibroblast growth factor binding protein 2b
chr16_-_42872571 0.30 ENSDART00000154757
ENSDART00000102345
thioredoxin interacting protein b
chr1_+_58079053 0.28 ENSDART00000141678
si:ch211-114l13.3
chr8_+_30921403 0.27 ENSDART00000043251
derlin 3
chr7_+_30051488 0.27 ENSDART00000169410
proline-serine-threonine phosphatase interacting protein 1b
chr8_-_1884955 0.27 ENSDART00000081563
si:dkey-178e17.3
chr23_+_6232895 0.27 ENSDART00000139795
synaptotagmin IIa
chr21_+_45366229 0.25 ENSDART00000029946
ubiquitin-conjugating enzyme E2B (RAD6 homolog)
chr7_+_6879534 0.24 ENSDART00000157731
zgc:175248
chr21_-_11791909 0.23 ENSDART00000180893
si:dkey-6b12.5
chr1_-_44704261 0.23 ENSDART00000133210
si:dkey-28b4.8
chr14_-_1355544 0.21 ENSDART00000060417
centrin 4
chr5_+_61799629 0.21 ENSDART00000113508
heterogeneous nuclear ribonucleoprotein U-like 1 like
chr16_-_30969294 0.20 ENSDART00000147890
diacylglycerol O-acyltransferase 1b
chr4_+_38550788 0.18 ENSDART00000157412
si:ch211-209n20.1
chr21_-_4923427 0.18 ENSDART00000181489
potassium channel, subfamily T, member 1
chr2_+_25840463 0.16 ENSDART00000125178
eukaryotic translation initiation factor 5A2
chr5_+_9297585 0.16 ENSDART00000170557
si:ch73-194c23.1
chr22_-_18387059 0.16 ENSDART00000007769
testis-specific serine kinase 6
chr7_-_34225011 0.16 ENSDART00000049588
crystallin beta gamma X
chr2_+_15776649 0.14 ENSDART00000156535
vav 3 guanine nucleotide exchange factor b
chr16_+_34531486 0.14 ENSDART00000043291
progestin and adipoQ receptor family member VII, b
chr2_-_27329214 0.14 ENSDART00000145835
thioredoxin related transmembrane protein 3a
chr3_+_62196672 0.14 ENSDART00000097312
SCO1 cytochrome c oxidase assembly protein
chr3_-_24458281 0.12 ENSDART00000153993
BAI1-associated protein 2-like 2a
chr19_+_42770041 0.11 ENSDART00000150930
cytoplasmic linker associated protein 2
chr2_+_15776408 0.10 ENSDART00000176628
vav 3 guanine nucleotide exchange factor b
chr19_+_7878122 0.09 ENSDART00000131917
si:dkeyp-85e10.2
chr13_+_22964868 0.09 ENSDART00000142129
tachykinin receptor 2
chr2_-_54639964 0.07 ENSDART00000100103
acyl-CoA synthetase short chain family member 2 like
chr16_-_11986321 0.07 ENSDART00000148666
ENSDART00000029121
ubiquitin specific peptidase 5 (isopeptidase T)
chr2_+_45484183 0.07 ENSDART00000183490
si:ch211-66k16.28
chr16_+_32092866 0.05 ENSDART00000137785
si:dkey-40m6.11
chr7_-_36358735 0.05 ENSDART00000188392
fat mass and obesity associated
chr16_+_27224068 0.02 ENSDART00000059013
Sec61 translocon beta subunit
chr3_-_3019979 0.01 ENSDART00000111174
zgc:172090
chr17_-_36841981 0.01 ENSDART00000131566
myosin VIb
chr20_+_39375280 0.00 ENSDART00000172434
Pim proto-oncogene, serine/threonine kinase, related 131

Network of associatons between targets according to the STRING database.

First level regulatory network of zbtb3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.4 GO:1900619 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.4 1.7 GO:0021742 abducens nucleus development(GO:0021742)
0.4 1.9 GO:0031174 lifelong otolith mineralization(GO:0031174)
0.3 1.7 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.2 0.7 GO:0019695 choline metabolic process(GO:0019695)
0.2 3.8 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.2 0.6 GO:0046048 pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048)
0.2 2.4 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.2 2.8 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.1 1.3 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.1 0.9 GO:0045475 locomotor rhythm(GO:0045475)
0.1 0.5 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 2.6 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.1 0.6 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.1 0.8 GO:2000406 positive regulation of lymphocyte migration(GO:2000403) positive regulation of T cell migration(GO:2000406)
0.1 0.3 GO:0010269 response to selenium ion(GO:0010269)
0.0 0.3 GO:0036268 swimming(GO:0036268)
0.0 1.1 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.8 GO:1902807 negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 1.3 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.2 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.0 0.1 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 3.0 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.7 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 2.3 GO:0055113 epiboly involved in gastrulation with mouth forming second(GO:0055113)
0.0 0.6 GO:0051932 synaptic transmission, GABAergic(GO:0051932)
0.0 0.2 GO:0045901 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.6 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.0 GO:0042245 RNA repair(GO:0042245)
0.0 0.4 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 0.1 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.1 GO:1902093 positive regulation of sperm motility(GO:1902093)
0.0 0.1 GO:0006083 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.0 0.3 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 1.8 GO:0070507 regulation of microtubule cytoskeleton organization(GO:0070507)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.4 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1 2.2 GO:0030315 T-tubule(GO:0030315)
0.1 1.4 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.6 GO:0030891 VCB complex(GO:0030891)
0.1 0.4 GO:0070743 interleukin-12 complex(GO:0043514) interleukin-23 complex(GO:0070743)
0.1 3.0 GO:0008305 integrin complex(GO:0008305)
0.1 0.3 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 0.3 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 0.3 GO:0033503 HULC complex(GO:0033503)
0.0 0.7 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.8 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.5 GO:0030175 filopodium(GO:0030175)
0.0 1.0 GO:0016605 PML body(GO:0016605)
0.0 0.6 GO:0032589 neuron projection membrane(GO:0032589) dendrite membrane(GO:0032590)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.7 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 2.8 GO:0030017 sarcomere(GO:0030017)
0.0 1.3 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.1 GO:0097225 sperm midpiece(GO:0097225)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.4 2.4 GO:0004104 cholinesterase activity(GO:0004104)
0.2 1.0 GO:0005521 lamin binding(GO:0005521)
0.2 0.8 GO:0038132 neuregulin receptor activity(GO:0038131) neuregulin binding(GO:0038132)
0.1 1.3 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 1.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.4 GO:0019972 interleukin-12 binding(GO:0019972) interleukin-12 alpha subunit binding(GO:0042164)
0.1 0.3 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.1 2.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 0.5 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 1.6 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 0.8 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 2.6 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.6 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.0 1.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.7 GO:0003954 NADH dehydrogenase activity(GO:0003954)
0.0 0.6 GO:0010181 FMN binding(GO:0010181)
0.0 0.2 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.6 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.5 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.9 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.5 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.1 GO:0016972 thiol oxidase activity(GO:0016972)
0.0 1.1 GO:0046332 SMAD binding(GO:0046332)
0.0 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.4 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.0 GO:0043734 oxidative DNA demethylase activity(GO:0035516) DNA-N1-methyladenine dioxygenase activity(GO:0043734) RNA N6-methyladenosine dioxygenase activity(GO:1990931)
0.0 1.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.5 GO:0004222 metalloendopeptidase activity(GO:0004222)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.8 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 1.5 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 2.4 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.8 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.5 PID ILK PATHWAY Integrin-linked kinase signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.2 1.6 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2 1.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 2.3 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 0.4 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.8 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.5 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR