ISMARA results: zbtb18+zbtb42

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PRJNA195909:zebrafish embryo and larva development

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Results for zbtb18+zbtb42

Z-value: 1.70

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Transcription factors associated with zbtb18+zbtb42

Gene Symbol	Gene ID	Gene Info
zbtb18 NCBI UniProt	ENSDARG00000028228	zinc finger and BTB domain containing 18
zbtb42 NCBI UniProt	ENSDARG00000102761	zinc finger and BTB domain containing 42

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
zbtb18	dr11_v1_chr13_+_11436130_11436130	0.62	7.3e-02	Click!
zbtb42	dr11_v1_chr17_-_1407593_1407725	-0.38	3.1e-01	Click!

Activity profile of zbtb18+zbtb42 motif

Sorted Z-values of zbtb18+zbtb42 motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr24_-_26282672 Show fit	3.58	ENSDART00000176663	and1 NCBI UniProt Show fit	actinodin1
chr25_+_31277415 Show fit	3.01	ENSDART00000036275	tnni2a.4 NCBI UniProt Show fit	troponin I type 2a (skeletal, fast), tandem duplicate 4
chr23_+_21473103 Show fit	2.78	ENSDART00000142921	si:ch73-21g5.7 NCBI UniProt Show fit	si:ch73-21g5.7
chr23_-_21453614 Show fit	2.69	ENSDART00000079274	her4.1 NCBI UniProt Show fit	hairy-related 4, tandem duplicate 1
chr1_+_31864404 Show fit	2.59	ENSDART00000075260	inab NCBI UniProt Show fit	internexin neuronal intermediate filament protein, alpha b
chr25_+_31276842 Show fit	2.56	ENSDART00000187238	tnni2a.4 NCBI UniProt Show fit	troponin I type 2a (skeletal, fast), tandem duplicate 4
chr11_-_24681292 Show fit	2.53	ENSDART00000089601	olfml3b NCBI UniProt Show fit	olfactomedin-like 3b
chr1_+_45351890 Show fit	2.45	ENSDART00000145486	si:ch211-243a20.3 NCBI UniProt Show fit	si:ch211-243a20.3
chr23_-_21471022 Show fit	2.36	ENSDART00000104206	her4.2 NCBI UniProt Show fit	hairy-related 4, tandem duplicate 2
chr10_-_29903165 Show fit	2.35	ENSDART00000078800	lim2.1 NCBI UniProt Show fit	lens intrinsic membrane protein 2.1

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of zbtb18+zbtb42

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.4	9.4	GO:0048936	peripheral nervous system neuron axonogenesis(GO:0048936)
0.1	5.6	GO:0003009	skeletal muscle contraction(GO:0003009)
0.1	2.6	GO:0006383	transcription from RNA polymerase III promoter(GO:0006383)
0.0	2.4	GO:0021782	glial cell development(GO:0021782)
0.0	2.3	GO:0033333	fin development(GO:0033333)
0.1	2.2	GO:0007520	myoblast fusion(GO:0007520)
0.0	2.2	GO:0007601	visual perception(GO:0007601)
0.1	2.1	GO:0048512	rhythmic behavior(GO:0007622) circadian behavior(GO:0048512)
0.0	2.0	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
0.1	1.7	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)

Showing 1 to 10 of 73 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	21.4	GO:0005576	extracellular region(GO:0005576)
0.1	5.6	GO:0005861	troponin complex(GO:0005861)
0.1	2.7	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.5	2.6	GO:0005883	neurofilament(GO:0005883)
0.1	2.3	GO:0031680	G-protein beta/gamma-subunit complex(GO:0031680)
0.0	2.1	GO:0005925	focal adhesion(GO:0005925)
0.0	1.9	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.1	1.7	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
0.0	1.5	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.3	1.4	GO:0070724	BMP receptor complex(GO:0070724)

Showing 1 to 10 of 22 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	8.4	GO:0046983	protein dimerization activity(GO:0046983)
0.4	2.7	GO:0034632	retinol transporter activity(GO:0034632)
0.0	2.4	GO:0005212	structural constituent of eye lens(GO:0005212)
0.1	2.3	GO:0031681	G-protein beta-subunit binding(GO:0031681)
0.4	2.2	GO:0004082	bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.0	1.9	GO:0008201	heparin binding(GO:0008201)
0.1	1.8	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
0.1	1.7	GO:0015002	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	1.7	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.1	1.6	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)

Showing 1 to 10 of 51 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	2.9	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.1	2.2	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.2	1.7	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.1	1.4	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.1	1.4	PID ALK1 PATHWAY	ALK1 signaling events
0.0	1.4	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.8	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	0.7	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.7	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	0.7	PID FGF PATHWAY	FGF signaling pathway

Showing 1 to 10 of 17 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.0	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.1	2.3	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.2	2.2	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.1	1.4	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	1.2	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.1	0.7	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.7	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.7	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.6	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	0.5	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation

Showing 1 to 10 of 15 entries

Results for zbtb18+zbtb42

Z-value: 1.70

Motif logo

Transcription factors associated with zbtb18+zbtb42

Activity-expression correlation:

Activity profile of zbtb18+zbtb42 motif

Sorted Z-values of zbtb18+zbtb42 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of zbtb18+zbtb42

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: