Project

PRJNA195909:zebrafish embryo and larva development

Navigation
Downloads

Results for zbtb12.2

Z-value: 0.87

Motif logo

logo of

Transcription factors associated with zbtb12.2

Gene Symbol Gene ID Gene Info
zbtb12.2
ENSDARG00000070658 zinc finger and BTB domain containing 12, tandem duplicate 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
zbtb12.2dr11_v1_chr19_-_26964348_26964348-0.235.4e-01Click!

Activity profile of zbtb12.2 motif

Sorted Z-values of zbtb12.2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_17114852 1.85 ENSDART00000006549
pif1
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr24_-_28259127 1.83 ENSDART00000149589
prkag2a
protein kinase, AMP-activated, gamma 2 non-catalytic subunit a
chr19_-_27579805 1.70 ENSDART00000132980
ENSDART00000142263
si:dkeyp-46h3.3
si:dkeyp-46h3.3
chr2_-_17115256 1.69 ENSDART00000190488
pif1
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr2_+_30547018 1.61 ENSDART00000193747
ankrd33bb
ankyrin repeat domain 33Bb
chr12_+_9849476 1.43 ENSDART00000110458
fam117ab
family with sequence similarity 117, member Ab
chr5_+_25311309 1.37 ENSDART00000169638
wu:fa19b12
wu:fa19b12
chr15_+_38299563 1.35 ENSDART00000099375
si:dkey-24p1.6
si:dkey-24p1.6
chr21_+_20386865 1.29 ENSDART00000144366
si:dkey-30k6.5
si:dkey-30k6.5
chr25_-_7649736 1.13 ENSDART00000149548
myo5ab
myosin VAb
chr22_-_9861531 1.04 ENSDART00000193197
si:dkey-253d23.2
si:dkey-253d23.2
chr6_+_2195625 1.04 ENSDART00000155659
acvr1bb
activin A receptor type 1Bb
chr17_-_12249990 1.01 ENSDART00000177889
ENSDART00000155545
ahctf1
AT hook containing transcription factor 1
chr13_+_46941930 0.99 ENSDART00000056962
fbxo5
F-box protein 5
chr14_-_6527010 0.98 ENSDART00000125058
nipsnap3a
nipsnap homolog 3A (C. elegans)
chr20_-_29532939 0.94 ENSDART00000049224
ENSDART00000062377
taf1b
TATA box binding protein (Tbp)-associated factor, RNA polymerase I, B
chr16_+_53526135 0.92 ENSDART00000083558
smpd5
sphingomyelin phosphodiesterase 5
chr16_-_42175617 0.87 ENSDART00000084715
alkbh8
alkB homolog 8, tRNA methyltransferase
chr6_+_11397269 0.87 ENSDART00000114260
senp2
SUMO1/sentrin/SMT3 specific peptidase 2
chr19_-_24136233 0.83 ENSDART00000143365
thap7
THAP domain containing 7
chr10_+_9595575 0.83 ENSDART00000091780
ENSDART00000184287
rc3h2
ring finger and CCCH-type domains 2
chr19_+_26640096 0.81 ENSDART00000067793
ints3
integrator complex subunit 3
chr17_-_27419499 0.78 ENSDART00000186773
ythdf2
YTH N(6)-methyladenosine RNA binding protein 2
chr1_-_40341306 0.76 ENSDART00000190649
maml3
mastermind-like transcriptional coactivator 3
chr3_-_36364903 0.75 ENSDART00000028883
gna13b
guanine nucleotide binding protein (G protein), alpha 13b
chr10_+_42691210 0.73 ENSDART00000193813
rhobtb2b
Rho-related BTB domain containing 2b
chr6_-_1566407 0.70 ENSDART00000112118
trim107
tripartite motif containing 107
chr23_+_39963599 0.69 ENSDART00000166539
fyco1a
FYVE and coiled-coil domain containing 1a
chr17_-_27419319 0.68 ENSDART00000127043
ythdf2
YTH N(6)-methyladenosine RNA binding protein 2
chr22_+_2512154 0.62 ENSDART00000097363
zgc:173726
zgc:173726
chr20_+_38458084 0.62 ENSDART00000020153
ENSDART00000135912
coq8a
coenzyme Q8A
chr7_+_34297271 0.61 ENSDART00000180342
bbox1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr1_+_218524 0.60 ENSDART00000109529
tmco3
transmembrane and coiled-coil domains 3
chr22_-_14475927 0.60 ENSDART00000135768
lrp1ba
low density lipoprotein receptor-related protein 1Ba
chr21_-_28737320 0.59 ENSDART00000098696
ENSDART00000124826
ENSDART00000125652
nrg2a
neuregulin 2a
chr6_-_24392426 0.59 ENSDART00000163965
brdt
bromodomain, testis-specific
chr6_-_1566186 0.56 ENSDART00000156305
trim107
tripartite motif containing 107
chr1_+_54194801 0.56 ENSDART00000186802
CABZ01067150.1

chr22_+_1300587 0.55 ENSDART00000124161
si:ch73-138e16.5
si:ch73-138e16.5
chr21_+_10076203 0.55 ENSDART00000190383
CABZ01043506.1

chr22_+_2048566 0.53 ENSDART00000169234
si:dkey-1b17.9
si:dkey-1b17.9
chr5_-_66823750 0.53 ENSDART00000041441
ENSDART00000112488
stip1
stress-induced phosphoprotein 1
chr22_+_2144278 0.52 ENSDART00000162173
ENSDART00000159914
ENSDART00000160192
znf1164
zinc finger protein 1164
chr3_+_43373867 0.52 ENSDART00000159455
ENSDART00000172425
zfand2a
zinc finger, AN1-type domain 2A
chr11_+_2855430 0.52 ENSDART00000172837
kif21b
kinesin family member 21B
chr6_+_12482599 0.50 ENSDART00000090316
stk24b
serine/threonine kinase 24b (STE20 homolog, yeast)
chr7_+_29024282 0.50 ENSDART00000076425
cog4
component of oligomeric golgi complex 4
chr5_-_42950963 0.43 ENSDART00000149868
grsf1
G-rich RNA sequence binding factor 1
chr11_-_18254 0.42 ENSDART00000167814
prr13
proline rich 13
chr7_+_21768452 0.42 ENSDART00000127719
kdm6ba
lysine (K)-specific demethylase 6B, a
chr4_+_20085114 0.36 ENSDART00000186698
ENSDART00000188635
ppp6r2a
protein phosphatase 6, regulatory subunit 2a
chr13_-_50446872 0.35 ENSDART00000083883
herc4
HECT and RLD domain containing E3 ubiquitin protein ligase 4
chr19_+_3140313 0.35 ENSDART00000125504
zgc:86598
zgc:86598
chr21_+_1587722 0.34 ENSDART00000013581
wdr91
WD repeat domain 91
chr22_+_1837448 0.32 ENSDART00000160015
znf1183
zinc finger protein 1183
chr3_-_15645405 0.31 ENSDART00000133957
si:dkey-93n13.1
si:dkey-93n13.1
chr6_-_46053300 0.31 ENSDART00000169722
ca16b
carbonic anhydrase XVI b
chr3_-_61345723 0.29 ENSDART00000156749
si:dkey-111k8.5
si:dkey-111k8.5
chr4_+_16323970 0.29 ENSDART00000190651
BX322608.1

chr11_+_1551603 0.28 ENSDART00000185383
ENSDART00000121489
ENSDART00000040577
mybl2b
v-myb avian myeloblastosis viral oncogene homolog-like 2b
chr18_+_8402129 0.28 ENSDART00000081154
ENSDART00000171974
prpf18
PRP18 pre-mRNA processing factor 18 homolog (yeast)
chr21_-_43171249 0.28 ENSDART00000021037
ENSDART00000148630
hspa4a
heat shock protein 4a
chr19_+_20793388 0.27 ENSDART00000142463
txnl4a
thioredoxin-like 4A
chr17_-_50454957 0.26 ENSDART00000171616
ENSDART00000075195
si:ch211-235i11.7
si:ch211-235i11.7
chr14_+_46342882 0.25 ENSDART00000193707
ENSDART00000060577
tmem33
transmembrane protein 33
chr21_+_43171013 0.25 ENSDART00000151362
zcchc10
zinc finger, CCHC domain containing 10
chr19_+_3215466 0.24 ENSDART00000181288
zgc:86598
zgc:86598
chr17_-_50436199 0.23 ENSDART00000156494
si:ch211-235i11.6
si:ch211-235i11.6
chr16_-_10837245 0.23 ENSDART00000036891
rabac1
Rab acceptor 1 (prenylated)
chr3_+_62339264 0.22 ENSDART00000174569
BX470259.3

chr6_+_20954400 0.22 ENSDART00000143248
ENSDART00000165806
stk11ip
serine/threonine kinase 11 interacting protein
chr11_-_18449 0.20 ENSDART00000172050
prr13
proline rich 13
chr8_-_50132860 0.20 ENSDART00000149964
antxr1a
anthrax toxin receptor 1a
chr6_-_22369125 0.20 ENSDART00000083038
nprl2
NPR2 like, GATOR1 complex subunit
chr19_+_20793237 0.19 ENSDART00000014774
txnl4a
thioredoxin-like 4A
chr1_-_45888608 0.18 ENSDART00000139219
pnpla6
patatin-like phospholipase domain containing 6
chr24_-_7957581 0.17 ENSDART00000145815
txndc5
thioredoxin domain containing 5
chr2_+_22602301 0.16 ENSDART00000038514
sept2
septin 2
chr5_+_31944270 0.15 ENSDART00000147850
ungb
uracil DNA glycosylase b
chr3_+_1005059 0.15 ENSDART00000132460
zgc:172051
zgc:172051
chr10_+_29849497 0.14 ENSDART00000099994
ENSDART00000132212
hspa8
heat shock protein 8
chr14_-_14607855 0.12 ENSDART00000162322
rab9b
RAB9B, member RAS oncogene family
chr3_-_7129057 0.11 ENSDART00000125947
BX005085.1

chr3_-_2033105 0.09 ENSDART00000135249
si:dkey-88j15.3
si:dkey-88j15.3
chr3_-_61354239 0.09 ENSDART00000154312
znf1134
zinc finger protein 1134
chr8_-_13428740 0.08 ENSDART00000131826
CR354547.3

chr24_+_42148140 0.07 ENSDART00000010658
serpinb1l3
serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 3
chr2_+_20332044 0.07 ENSDART00000112131
plppr4a
phospholipid phosphatase related 4a
chr3_-_136043 0.06 ENSDART00000160266
zgc:110249
zgc:110249
chr23_-_26522760 0.06 ENSDART00000142417
ENSDART00000135606
ENSDART00000122668
si:dkey-205h13.1
si:dkey-205h13.1
chr22_+_2239974 0.05 ENSDART00000141993
znf1144
zinc finger protein 1144
chr12_-_48312647 0.04 ENSDART00000114415
ascc1
activating signal cointegrator 1 complex subunit 1
chr18_+_16963881 0.03 ENSDART00000147583
si:ch211-242e8.1
si:ch211-242e8.1
chr15_-_41486793 0.01 ENSDART00000138525
si:ch211-187g4.1
si:ch211-187g4.1
chr22_+_9287929 0.01 ENSDART00000193522
si:ch211-250k18.7
si:ch211-250k18.7

Network of associatons between targets according to the STRING database.

First level regulatory network of zbtb12.2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:1903537 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.3 3.5 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.2 1.0 GO:1904667 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.2 1.0 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.2 0.6 GO:0001207 histone displacement(GO:0001207) regulation of transcription involved in meiotic cell cycle(GO:0051037) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.2 0.8 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.2 0.9 GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.2 0.8 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.4 GO:0061383 trabecula morphogenesis(GO:0061383) heart trabecula morphogenesis(GO:0061384)
0.1 0.7 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 0.3 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.1 0.9 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.6 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 0.6 GO:0060347 ventricular trabecula myocardium morphogenesis(GO:0003222) trabecula formation(GO:0060343) heart trabecula formation(GO:0060347) skin epidermis development(GO:0098773)
0.1 0.9 GO:0016926 protein desumoylation(GO:0016926)
0.0 1.8 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.8 GO:0044818 mitotic G2/M transition checkpoint(GO:0044818)
0.0 0.9 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.2 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
0.0 0.1 GO:0097510 base-excision repair, AP site formation via deaminated base removal(GO:0097510)
0.0 0.3 GO:0043550 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.1 GO:1902946 positive regulation of receptor-mediated endocytosis(GO:0048260) protein localization to early endosome(GO:1902946)
0.0 1.1 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 1.0 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.0 0.7 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 0.4 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.8 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
0.0 0.1 GO:1901998 toxin transport(GO:1901998)
0.0 0.2 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 0.2 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 0.2 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.0 0.5 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.2 1.8 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 0.8 GO:0070876 SOSS complex(GO:0070876)
0.1 0.8 GO:0031526 brush border membrane(GO:0031526)
0.1 1.0 GO:0048179 activin receptor complex(GO:0048179)
0.1 3.5 GO:0005657 replication fork(GO:0005657)
0.1 0.3 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.6 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.7 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.5 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.2 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.8 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.9 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 1.5 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.7 GO:0005776 autophagosome(GO:0005776)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.5 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.3 0.9 GO:0001164 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.3 0.9 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.3 0.8 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.2 1.5 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.2 0.6 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.2 1.0 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 0.8 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 0.9 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 1.8 GO:0016208 AMP binding(GO:0016208)
0.1 0.9 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.4 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.5 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 1.1 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.3 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.0 0.2 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.1 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.5 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.0 PID PLK1 PATHWAY PLK1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 0.4 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.1 0.8 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.9 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 1.0 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 1.0 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.5 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.3 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis