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PRJNA195909:zebrafish embryo and larva development
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Results for ybx1
Z-value: 0.92
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Transcription factors associated with ybx1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ybx1 | dr11_v1_chr8_-_47152001_47152086 | -0.82 | 6.5e-03 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr19_+_14109348 Show fit | 2.31 |
ENSDART00000159015
|
zgc:175136 |
|
| chr20_-_52939501 Show fit | 2.25 |
ENSDART00000166508
|
farnesyl-diphosphate farnesyltransferase 1 |
|
| chr9_+_29548195 Show fit | 1.77 |
ENSDART00000176057
|
ring finger protein 17 |
|
| chr12_+_38807604 Show fit | 1.46 |
ENSDART00000155563
|
ATP-binding cassette, sub-family A (ABC1), member 5 |
|
| chr18_+_27515640 Show fit | 1.43 |
ENSDART00000181593
|
tumor protein p53 inducible protein 11b |
|
| chr10_+_6010570 Show fit | 1.20 |
ENSDART00000190025
ENSDART00000163680 |
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
|
| chr14_-_8903435 Show fit | 1.14 |
ENSDART00000160584
|
zgc:153681 |
|
| chr9_+_45227028 Show fit | 1.11 |
ENSDART00000185579
|
adenosine deaminase, RNA-specific, B1b |
|
| chr16_-_39477746 Show fit | 1.08 |
ENSDART00000102525
|
STT3B, subunit of the oligosaccharyltransferase complex (catalytic) |
|
| chr2_-_17115256 Show fit | 1.05 |
ENSDART00000190488
|
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae) |
Network of associatons between targets according to the STRING database.
First level regulatory network of ybx1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 3.5 | GO:0045338 | farnesyl diphosphate metabolic process(GO:0045338) |
| 0.2 | 2.4 | GO:0060236 | regulation of mitotic spindle organization(GO:0060236) |
| 0.1 | 2.1 | GO:0018279 | protein N-linked glycosylation via asparagine(GO:0018279) post-translational protein modification(GO:0043687) |
| 0.0 | 2.0 | GO:0016579 | protein deubiquitination(GO:0016579) |
| 0.1 | 1.8 | GO:0032007 | negative regulation of TOR signaling(GO:0032007) |
| 0.1 | 1.7 | GO:0009648 | photoperiodism(GO:0009648) |
| 0.0 | 1.6 | GO:0006338 | chromatin remodeling(GO:0006338) |
| 0.0 | 1.6 | GO:0043484 | regulation of RNA splicing(GO:0043484) |
| 0.2 | 1.4 | GO:0031507 | heterochromatin assembly(GO:0031507) |
| 0.0 | 1.4 | GO:0006334 | nucleosome assembly(GO:0006334) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.6 | GO:0000786 | nucleosome(GO:0000786) |
| 0.1 | 1.6 | GO:0034751 | aryl hydrocarbon receptor complex(GO:0034751) |
| 0.1 | 1.5 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.0 | 1.4 | GO:0016514 | SWI/SNF complex(GO:0016514) |
| 0.0 | 1.4 | GO:0005657 | replication fork(GO:0005657) |
| 0.0 | 1.4 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.1 | 0.9 | GO:0000792 | heterochromatin(GO:0000792) |
| 0.1 | 0.8 | GO:0048179 | activin receptor complex(GO:0048179) |
| 0.2 | 0.7 | GO:0046695 | SLIK (SAGA-like) complex(GO:0046695) |
| 0.1 | 0.7 | GO:0061700 | GATOR2 complex(GO:0061700) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.8 | GO:0046982 | protein heterodimerization activity(GO:0046982) |
| 0.8 | 2.3 | GO:0004311 | farnesyltranstransferase activity(GO:0004311) |
| 0.5 | 2.1 | GO:0004579 | oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.1 | 2.0 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.0 | 2.0 | GO:0101005 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005) |
| 0.4 | 1.2 | GO:0004421 | hydroxymethylglutaryl-CoA synthase activity(GO:0004421) |
| 0.1 | 1.2 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
| 0.0 | 1.2 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 0.2 | 1.1 | GO:0043139 | 5'-3' DNA helicase activity(GO:0043139) |
| 0.1 | 1.1 | GO:0019871 | sodium channel inhibitor activity(GO:0019871) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.6 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.0 | 1.4 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
| 0.0 | 1.4 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.0 | 1.2 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 1.1 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 0.0 | 1.0 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.1 | 0.7 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.0 | 0.6 | PID AURORA A PATHWAY | Aurora A signaling |
| 0.0 | 0.6 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.0 | 0.5 | PID WNT CANONICAL PATHWAY | Canonical Wnt signaling pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.6 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.1 | 2.0 | REACTOME PERK REGULATED GENE EXPRESSION | Genes involved in PERK regulated gene expression |
| 0.0 | 0.8 | REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
| 0.0 | 0.8 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.1 | 0.7 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.0 | 0.7 | REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
| 0.0 | 0.7 | REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE | Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle |
| 0.0 | 0.7 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.0 | 0.5 | REACTOME VITAMIN B5 PANTOTHENATE METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
| 0.0 | 0.5 | REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |