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PRJNA195909:zebrafish embryo and larva development

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Results for ybx1

Z-value: 0.92

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Transcription factors associated with ybx1

Gene Symbol Gene ID Gene Info
ENSDARG00000004757 Y box binding protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ybx1dr11_v1_chr8_-_47152001_47152086-0.826.5e-03Click!

Activity profile of ybx1 motif

Sorted Z-values of ybx1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_14109348 2.31 ENSDART00000159015
zgc:175136
chr20_-_52939501 2.25 ENSDART00000166508
farnesyl-diphosphate farnesyltransferase 1
chr9_+_29548195 1.77 ENSDART00000176057
ring finger protein 17
chr12_+_38807604 1.46 ENSDART00000155563
ATP-binding cassette, sub-family A (ABC1), member 5
chr18_+_27515640 1.43 ENSDART00000181593
tumor protein p53 inducible protein 11b
chr10_+_6010570 1.20 ENSDART00000190025
ENSDART00000163680
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr14_-_8903435 1.14 ENSDART00000160584
zgc:153681
chr9_+_45227028 1.11 ENSDART00000185579
adenosine deaminase, RNA-specific, B1b
chr16_-_39477746 1.08 ENSDART00000102525
STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
chr2_-_17115256 1.05 ENSDART00000190488
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr12_-_24832297 1.05 ENSDART00000066317
forkhead box N2b
chr7_-_73845736 1.05 ENSDART00000193414
zgc:173552
chr10_-_45029041 1.05 ENSDART00000167878
polymerase (DNA directed), mu
chr7_+_57088920 1.04 ENSDART00000024076
secretory carrier membrane protein 2, like
chr12_+_1469090 1.03 ENSDART00000183637
ubiquitin specific peptidase 22
chr16_-_39477509 0.99 ENSDART00000191330
STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
chr12_+_1469327 0.99 ENSDART00000059143
ubiquitin specific peptidase 22
chr1_+_30723677 0.97 ENSDART00000177900
bora, aurora kinase A activator
chr22_-_5171829 0.96 ENSDART00000140313
tumor necrosis factor, alpha-induced protein 8-like 1
chr1_+_30723380 0.96 ENSDART00000127943
ENSDART00000062628
ENSDART00000127670
bora, aurora kinase A activator
chr20_-_49889111 0.94 ENSDART00000058858
kinesin family member 13Bb
chr8_-_1219815 0.89 ENSDART00000016800
ENSDART00000149969
zinc finger protein 367
chr22_-_4439311 0.89 ENSDART00000169317
ubiquitin-like with PHD and ring finger domains 1
chr22_-_5171362 0.88 ENSDART00000124889
tumor necrosis factor, alpha-induced protein 8-like 1
chr7_+_26549846 0.88 ENSDART00000141353
tyrosine kinase, non-receptor, 1
chr16_+_45930962 0.87 ENSDART00000124689
ENSDART00000041811
OTU deubiquitinase 7B
chr7_+_38529263 0.87 ENSDART00000109495
ENSDART00000173804
nudix (nucleoside diphosphate linked moiety X)-type motif 19
chr7_+_5906327 0.86 ENSDART00000173160
zgc:112234
chr25_-_17918536 0.85 ENSDART00000148660
aryl hydrocarbon receptor nuclear translocator-like 1a
chr18_-_18942098 0.85 ENSDART00000100458
si:dkey-73n10.1
chr8_+_54081819 0.82 ENSDART00000005857
ENSDART00000161795
prickle homolog 2a
chr2_-_17492080 0.80 ENSDART00000024302
lysine (K)-specific demethylase 4A, genome duplicate b
chr24_-_24271629 0.78 ENSDART00000135060
ribosomal protein S6 kinase, polypeptide 3b
chr5_+_45139196 0.78 ENSDART00000113738
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr24_-_41220538 0.77 ENSDART00000150207
activin A receptor type 2Ba
chr7_-_73854476 0.77 ENSDART00000186481
zgc:173552
chr3_+_3810919 0.77 ENSDART00000056035

chr13_+_2394264 0.74 ENSDART00000168595
ELOVL fatty acid elongase 5
chr16_-_12095144 0.74 ENSDART00000145106
peroxisomal biogenesis factor 5
chr5_-_14500622 0.74 ENSDART00000099566
si:ch211-244o22.2
chr7_+_17953589 0.74 ENSDART00000174778
ENSDART00000113120
TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor
chr3_+_1167026 0.74 ENSDART00000031823
ENSDART00000155340
TRIO and F-actin binding protein b
chr2_+_105748 0.74 ENSDART00000169601

chr25_-_17918810 0.73 ENSDART00000023959
aryl hydrocarbon receptor nuclear translocator-like 1a
chr18_+_660578 0.73 ENSDART00000161203
si:dkey-205h23.2
chr4_-_9196291 0.72 ENSDART00000153963
host cell factor C2
chr4_+_4079418 0.72 ENSDART00000028016
Wiskott-Aldrich syndrome-like b
chr14_-_30945515 0.72 ENSDART00000161540
si:zfos-80g12.1
chr8_-_39884359 0.72 ENSDART00000131372
malectin
chr12_+_24060894 0.71 ENSDART00000021298
ankyrin repeat and SOCS box containing 3
chr18_+_17600570 0.71 ENSDART00000175258
ENSDART00000151850
ENSDART00000151934
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr16_-_11241424 0.71 ENSDART00000134752
zinc finger protein 526
chr20_-_3403033 0.70 ENSDART00000092264
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr7_+_5976613 0.70 ENSDART00000173105
si:dkey-23a13.21
chr13_+_8892784 0.69 ENSDART00000075054
ENSDART00000143705
thyroid adenoma associated
chr21_+_3897680 0.69 ENSDART00000170653
dolichyldiphosphatase 1
chr25_+_25508495 0.68 ENSDART00000150719
PHD and ring finger domains 1
chr14_-_12020653 0.68 ENSDART00000106654
zinc finger protein 711
chr5_+_45138934 0.66 ENSDART00000041412
ENSDART00000136002
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr11_+_440305 0.65 ENSDART00000082517
RAB43, member RAS oncogene family
chr9_+_22677503 0.65 ENSDART00000131429
ENSDART00000080005
ENSDART00000101756
ENSDART00000138148
integrin, beta 5
chr19_+_42806812 0.65 ENSDART00000108775
ENSDART00000151653
upstream binding protein 1
chr1_+_12394205 0.64 ENSDART00000138622
ENSDART00000136421
ENSDART00000139440
ENSDART00000184296
ENSDART00000008127
zgc:77739
chr7_+_34794829 0.64 ENSDART00000009698
ENSDART00000075089
ENSDART00000173456
epithelial splicing regulatory protein 2
chr19_+_791538 0.63 ENSDART00000146554
ENSDART00000138406
transmembrane protein 79a
chr7_-_73834812 0.61 ENSDART00000128137
zgc:92594
chr6_+_60112200 0.61 ENSDART00000008243
PRELI domain containing 3
chr7_-_59123066 0.60 ENSDART00000175438
DENN/MADD domain containing 4C
chr17_+_23556764 0.60 ENSDART00000146787
pantothenate kinase 1a
chr21_-_11054605 0.59 ENSDART00000191378
ENSDART00000084061
neural precursor cell expressed, developmentally down-regulated 4-like
chr24_+_17334682 0.59 ENSDART00000018868
protein disulfide isomerase family A, member 4
chr5_+_20030414 0.59 ENSDART00000181430
ENSDART00000047841
ENSDART00000182813
small G protein signaling modulator 1a
chr25_-_6389713 0.59 ENSDART00000083539
SIN3 transcription regulator family member Aa
chr3_-_21062706 0.58 ENSDART00000155605
ENSDART00000153686
ENSDART00000157168
ENSDART00000156614
ENSDART00000155743
ENSDART00000156275
family with sequence similarity 57, member Ba
chr4_-_8060962 0.58 ENSDART00000146622
WNK lysine deficient protein kinase 1b
chr12_-_33582382 0.57 ENSDART00000009794
ENSDART00000136617
tudor and KH domain containing
chr19_-_31686252 0.57 ENSDART00000131721
RHO family interacting cell polarization regulator 2
chr25_-_35102781 0.57 ENSDART00000180881
ENSDART00000153747
si:dkey-108k21.24
chr7_+_5905091 0.56 ENSDART00000167099
Histone H3.2
chr15_+_26940569 0.55 ENSDART00000189636
ENSDART00000077172
breast carcinoma amplified sequence 3
chr16_+_6750289 0.55 ENSDART00000167736
zinc finger protein 236
chr1_+_54737353 0.54 ENSDART00000130675
ENSDART00000162075
phosphatidylinositol 4-kinase type 2 alpha
chr21_-_11054876 0.54 ENSDART00000146576
neural precursor cell expressed, developmentally down-regulated 4-like
chr25_-_6261693 0.54 ENSDART00000135808
iron-responsive element binding protein 2
chr10_-_35257458 0.54 ENSDART00000143890
ENSDART00000139107
ENSDART00000082445
proline rich 11
chr21_+_34981263 0.53 ENSDART00000132711
RNA binding motif protein 11
chr3_+_35498119 0.53 ENSDART00000178963
trinucleotide repeat containing 6a
chr15_+_25439106 0.53 ENSDART00000156252
apoptosis-inducing factor, mitochondrion-associated, 4
chr11_-_27778831 0.52 ENSDART00000023823
Cas scaffolding protein family member 4
chr23_-_10786400 0.52 ENSDART00000055038
RING1 and YY1 binding protein a
chr9_+_2452672 0.52 ENSDART00000193993
chimerin 1
chr21_-_1635268 0.51 ENSDART00000151258
zgc:152948
chr25_+_36312459 0.51 ENSDART00000182484

chr20_-_40487208 0.51 ENSDART00000075070
ENSDART00000142029
heat shock transcription factor 2
chr19_-_6134802 0.51 ENSDART00000140051
capicua transcriptional repressor a
chr24_-_36301072 0.49 ENSDART00000062736
CoA synthase
chr23_-_35483163 0.49 ENSDART00000138660
ENSDART00000113643
ENSDART00000189269
F-box protein 25
chr3_+_16664212 0.49 ENSDART00000013816
zgc:55558
chr1_+_54069450 0.49 ENSDART00000108601
ENSDART00000187878
DDB1 and CUL4 associated factor 15
chr9_-_1604601 0.49 ENSDART00000143130
alkylglycerone phosphate synthase
chr17_+_35097024 0.49 ENSDART00000026152
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2a
chr20_-_2641233 0.48 ENSDART00000145335
ENSDART00000133121
BUB1 mitotic checkpoint serine/threonine kinase
chr7_-_6444011 0.47 ENSDART00000173010
zgc:112234
chr6_+_37752781 0.47 ENSDART00000154364
HECT and RLD domain containing E3 ubiquitin protein ligase 2
chr15_+_25438714 0.47 ENSDART00000154164
apoptosis-inducing factor, mitochondrion-associated, 4
chr23_+_32028574 0.47 ENSDART00000145501
ENSDART00000143121
ENSDART00000111877
TPX2, microtubule-associated, homolog (Xenopus laevis)
chr3_+_36671585 0.47 ENSDART00000159033
nudE neurodevelopment protein 1
chr15_+_26941063 0.46 ENSDART00000149957
breast carcinoma amplified sequence 3
chr1_-_54972170 0.46 ENSDART00000150548
ENSDART00000038330
KH-type splicing regulatory protein
chr21_-_1642739 0.46 ENSDART00000151118
zgc:152948
chr2_+_58877162 0.46 ENSDART00000122174

chr7_+_73827805 0.46 ENSDART00000109316
zgc:173587
chr18_+_907266 0.46 ENSDART00000171729
pyruvate kinase M1/2a
chr11_+_31324335 0.46 ENSDART00000088093
signal-induced proliferation-associated 1 like 2
chr7_+_1521834 0.45 ENSDART00000174007
si:cabz01102082.1
chr23_-_2037566 0.45 ENSDART00000191312
ENSDART00000127443
PR domain containing 5
chr20_+_37866171 0.45 ENSDART00000153190
vasohibin 2
chr7_-_6431158 0.45 ENSDART00000173199
si:ch1073-153i20.5
chr7_-_6364168 0.45 ENSDART00000173332
zgc:112234
chr22_-_4407871 0.45 ENSDART00000162523
lysine (K)-specific demethylase 4B
chr15_-_6615555 0.45 ENSDART00000152725
ATM serine/threonine kinase
chr13_-_42536642 0.45 ENSDART00000134533
BTAF1 RNA polymerase II, B-TFIID transcription factor-associated
chr7_-_31794476 0.44 ENSDART00000142385
nucleosome assembly protein 1-like 4b
chr18_+_21273749 0.42 ENSDART00000143265
HYDIN, axonemal central pair apparatus protein
chr5_+_26686639 0.42 ENSDART00000079064
transport and golgi organization 2 homolog (Drosophila)
chr7_+_29115890 0.42 ENSDART00000052345
tnfrsf1a-associated via death domain
chr19_-_15420678 0.42 ENSDART00000151454
ENSDART00000027697
serine incorporator 2
chr3_+_17878124 0.42 ENSDART00000166430
ENSDART00000163421
ENSDART00000121473
DnaJ (Hsp40) homolog, subfamily C, member 7
chr20_+_50061890 0.41 ENSDART00000137725
cleavage and polyadenylation specific factor 2
chr1_-_50527964 0.41 ENSDART00000024984
3'-phosphoadenosine 5'-phosphosulfate synthase 1
chr1_-_54971968 0.41 ENSDART00000140016
KH-type splicing regulatory protein
chr20_+_21391181 0.41 ENSDART00000185158
ENSDART00000049586
ENSDART00000024922
jagged 2b
chr22_+_30543437 0.41 ENSDART00000137983
si:dkey-103k4.1
chr3_+_17878466 0.40 ENSDART00000180218
DnaJ (Hsp40) homolog, subfamily C, member 7
chr7_+_5965611 0.40 ENSDART00000115062
Histone H3.2
chr13_-_5257303 0.39 ENSDART00000110610
si:dkey-78p8.1
chr19_-_26769867 0.39 ENSDART00000043776
ENSDART00000159489
ENSDART00000138675
proline-rich coiled-coil 2A
chr7_+_5910467 0.38 ENSDART00000173232
si:ch211-113a14.22
chr11_-_45152702 0.38 ENSDART00000168066
arylformamidase
chr5_-_2721686 0.38 ENSDART00000169404
heat shock protein 5
chr12_-_10674606 0.37 ENSDART00000157919
mediator complex subunit 24
chr5_+_36439405 0.37 ENSDART00000102973
ectodysplasin A
chr3_-_13147310 0.36 ENSDART00000160840
protein kinase, cAMP-dependent, regulatory, type I, beta
chr3_-_1146497 0.35 ENSDART00000149061
si:ch73-211l13.2
chr23_+_36616717 0.35 ENSDART00000042701
ENSDART00000192980
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma a
chr3_-_10751491 0.35 ENSDART00000016351
zgc:112965
chr12_+_25432627 0.35 ENSDART00000011662
protein phosphatase, Mg2+/Mn2+ dependent, 1Bb
chr1_-_51710225 0.35 ENSDART00000057601
ENSDART00000152745
small nuclear ribonucleoprotein polypeptide B2
chr1_+_58840889 0.35 ENSDART00000098308
transmembrane p24 trafficking protein 1b
chr25_-_35110695 0.34 ENSDART00000099859
histone cluster 1 H2A family member 10
chr14_+_80685 0.34 ENSDART00000188443
stromal antigen 3
chr9_-_10068004 0.34 ENSDART00000011922
ENSDART00000162818
speckle-type POZ protein-like a
chr5_+_29726428 0.34 ENSDART00000143183
DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
chr8_-_4574328 0.34 ENSDART00000090731
DEAH (Asp-Glu-Ala-His) box polypeptide 37
chr1_-_12394048 0.34 ENSDART00000146067
ENSDART00000134708
sodium channel and clathrin linker 1
chr25_+_4541211 0.34 ENSDART00000129978
patatin-like phospholipase domain containing 2
chr24_-_39772045 0.33 ENSDART00000087441
si:ch211-276f18.2
chr20_+_28266892 0.33 ENSDART00000103330
ChaC, cation transport regulator homolog 1 (E. coli)
chr2_+_37480669 0.32 ENSDART00000029801
signal peptide peptidase-like 2
chr22_-_22301672 0.32 ENSDART00000111711
chromatin assembly factor 1, subunit A (p150)
chr1_+_51386649 0.32 ENSDART00000152289
autophagy related 4D, cysteine peptidase a
chr19_-_26770083 0.31 ENSDART00000193811
ENSDART00000174455
proline-rich coiled-coil 2A
chr7_+_73819078 0.31 ENSDART00000169756
Histone H2B 1/2
chr14_-_246342 0.31 ENSDART00000054823
aurora kinase B
chr16_-_52646789 0.30 ENSDART00000035761
ubiquitin protein ligase E3 component n-recognin 5
chr3_-_6417328 0.30 ENSDART00000160979
Jupiter microtubule associated homolog 1b
chr11_+_45436703 0.30 ENSDART00000168295
ENSDART00000173293
son of sevenless homolog 1 (Drosophila)
chr2_+_24867534 0.30 ENSDART00000158050
RAB3A, member RAS oncogene family, a
chr3_-_8765165 0.30 ENSDART00000191131

chr8_-_1266181 0.30 ENSDART00000148654
ENSDART00000149924
cell division cycle 14B
chr2_+_29249561 0.29 ENSDART00000099157
cadherin 18, type 2a
chr10_+_35257651 0.29 ENSDART00000028940
serine/threonine/tyrosine interacting-like 1
chr11_+_18612166 0.29 ENSDART00000162694
nuclear receptor coactivator 3
chr7_-_13884610 0.29 ENSDART00000006897
retinaldehyde binding protein 1a
chr1_+_49651016 0.29 ENSDART00000074380
ENSDART00000101017
testis specific, 10
chr7_-_6345507 0.28 ENSDART00000173032
Histone H3.2
chr7_+_24390939 0.28 ENSDART00000087494
ENSDART00000125463
HAUS augmin-like complex, subunit 3
chr20_-_7176809 0.28 ENSDART00000012247
ENSDART00000125019
24-dehydrocholesterol reductase
chr11_+_14321113 0.28 ENSDART00000039822
ENSDART00000137347
ENSDART00000132997
polypyrimidine tract binding protein 1b
chr5_+_24086227 0.27 ENSDART00000051549
ENSDART00000177458
ENSDART00000135934
tumor protein p53
chr5_+_26686279 0.27 ENSDART00000193543
transport and golgi organization 2 homolog (Drosophila)
chr16_-_12060770 0.27 ENSDART00000183237
ENSDART00000103948
si:ch211-69g19.2
chr19_-_24135824 0.27 ENSDART00000189505
ENSDART00000104087
THAP domain containing 7
chr13_-_9119867 0.27 ENSDART00000137255
si:dkey-112g5.15
chr7_-_6466119 0.27 ENSDART00000173138
zgc:112234
chr7_-_56835543 0.26 ENSDART00000010322
SUMO/sentrin peptidase family member, NEDD8 specific
chr25_-_36361697 0.26 ENSDART00000152388
si:ch211-113a14.22
chr25_-_35150933 0.26 ENSDART00000129254
zgc:173552
chr12_-_9796237 0.26 ENSDART00000149344
PR domain containing 9
chr5_+_26138313 0.26 ENSDART00000010041
dihydrofolate reductase
chr5_+_5398966 0.26 ENSDART00000139553
mitogen-activated protein kinase associated protein 1
chr12_+_40905427 0.26 ENSDART00000170526
ENSDART00000185771
ENSDART00000193945
cadherin 18
chr16_-_32672883 0.26 ENSDART00000124515
ENSDART00000190920
ENSDART00000188776
PNN-interacting serine/arginine-rich protein
chr23_+_37185247 0.26 ENSDART00000146269
von Willebrand factor A domain containing 5B1
chr18_-_2549198 0.26 ENSDART00000186516

chr19_+_2619444 0.26 ENSDART00000169483
family with sequence similarity 126, member A
chr6_+_59854224 0.25 ENSDART00000083499
lysine (K)-specific demethylase 6A, like
chr3_+_17951790 0.24 ENSDART00000164663
ATP citrate lyase a
chr1_+_43686251 0.24 ENSDART00000074604
ENSDART00000137791
CDGSH iron sulfur domain 2
chr10_-_2713228 0.23 ENSDART00000123754
ENSDART00000126236
mesoderm induction early response 1, family member 3 a

Network of associatons between targets according to the STRING database.

First level regulatory network of ybx1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.5 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
0.2 1.4 GO:0031507 heterochromatin assembly(GO:0031507)
0.2 0.7 GO:1903069 regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069)
0.2 0.6 GO:1990869 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869) negative regulation of lymphocyte migration(GO:2000402) negative regulation of T cell migration(GO:2000405)
0.2 0.9 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.2 2.4 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.2 0.5 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.2 0.5 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
0.2 0.5 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.1 1.1 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.1 0.4 GO:0050427 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.1 0.5 GO:0021557 oculomotor nerve development(GO:0021557)
0.1 0.8 GO:0016572 histone phosphorylation(GO:0016572)
0.1 2.1 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279) post-translational protein modification(GO:0043687)
0.1 0.2 GO:0070987 error-free translesion synthesis(GO:0070987)
0.1 0.7 GO:1901031 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.1 0.9 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1 0.3 GO:0010526 regulation of transposition, RNA-mediated(GO:0010525) negative regulation of transposition, RNA-mediated(GO:0010526) transposition, RNA-mediated(GO:0032197) positive regulation of neuron apoptotic process(GO:0043525) positive regulation of neuron death(GO:1901216)
0.1 1.1 GO:0006382 adenosine to inosine editing(GO:0006382)
0.1 0.9 GO:0044030 regulation of DNA methylation(GO:0044030)
0.1 1.1 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.1 0.7 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 0.3 GO:0097676 histone H3-K4 trimethylation(GO:0080182) histone H3-K36 dimethylation(GO:0097676)
0.1 0.3 GO:0010896 regulation of triglyceride catabolic process(GO:0010896) positive regulation of triglyceride catabolic process(GO:0010898)
0.1 1.1 GO:0034033 coenzyme A biosynthetic process(GO:0015937) nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.1 0.4 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 0.7 GO:0022615 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.1 0.3 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.1 0.5 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.1 0.5 GO:0051299 mitotic centrosome separation(GO:0007100) centrosome separation(GO:0051299)
0.1 0.3 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.1 0.3 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.1 0.7 GO:0035306 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.1 0.2 GO:0010259 multicellular organism aging(GO:0010259)
0.1 0.5 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 0.4 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 0.2 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.1 1.8 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.1 0.3 GO:1902914 negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.1 1.7 GO:0009648 photoperiodism(GO:0009648)
0.0 0.4 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.4 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.3 GO:0090134 establishment or maintenance of cytoskeleton polarity(GO:0030952) mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.0 0.6 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.4 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.3 GO:0006751 glutathione catabolic process(GO:0006751)
0.0 0.1 GO:0060907 dendritic cell antigen processing and presentation(GO:0002468) macrophage cytokine production(GO:0010934) regulation of macrophage cytokine production(GO:0010935) positive regulation of macrophage cytokine production(GO:0060907) negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 0.6 GO:1903286 positive regulation of sodium ion transport(GO:0010765) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 1.0 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.3 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.5 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.7 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.5 GO:0061647 histone H3-K9 methylation(GO:0051567) histone H3-K9 modification(GO:0061647)
0.0 0.3 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.2 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.7 GO:1990798 pancreas regeneration(GO:1990798)
0.0 0.5 GO:0007032 endosome organization(GO:0007032)
0.0 0.3 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.0 0.4 GO:0042026 protein refolding(GO:0042026)
0.0 0.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.4 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.8 GO:0006101 citrate metabolic process(GO:0006101) tricarboxylic acid metabolic process(GO:0072350)
0.0 0.7 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.2 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.0 0.2 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.0 0.2 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.4 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 2.0 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.8 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.0 0.7 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.3 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.5 GO:0007050 cell cycle arrest(GO:0007050)
0.0 1.4 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.8 GO:0006342 chromatin silencing(GO:0006342)
0.0 1.6 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 1.0 GO:0007030 Golgi organization(GO:0007030)
0.0 0.3 GO:0007634 optokinetic behavior(GO:0007634)
0.0 0.1 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0 0.2 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.4 GO:0042476 odontogenesis(GO:0042476)
0.0 0.5 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 1.6 GO:0043484 regulation of RNA splicing(GO:0043484)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0046695 SLIK (SAGA-like) complex(GO:0046695)
0.1 0.6 GO:0060171 stereocilium membrane(GO:0060171)
0.1 0.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.5 GO:0005880 nuclear microtubule(GO:0005880)
0.1 1.6 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.7 GO:0061700 GATOR2 complex(GO:0061700)
0.1 0.3 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 0.3 GO:0033186 CAF-1 complex(GO:0033186)
0.1 1.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.9 GO:0000792 heterochromatin(GO:0000792)
0.1 0.8 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.7 GO:0042575 DNA polymerase complex(GO:0042575)
0.1 0.3 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.6 GO:0016580 Sin3 complex(GO:0016580)
0.0 4.6 GO:0000786 nucleosome(GO:0000786)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 1.4 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.6 GO:0000813 ESCRT I complex(GO:0000813)
0.0 1.4 GO:0005657 replication fork(GO:0005657)
0.0 0.7 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.3 GO:0070652 HAUS complex(GO:0070652)
0.0 0.4 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.5 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.5 GO:0000780 condensed nuclear chromosome kinetochore(GO:0000778) condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.1 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.7 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.2 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 1.4 GO:0005871 kinesin complex(GO:0005871)
0.0 0.3 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.3 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.6 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.3 GO:0008278 cohesin complex(GO:0008278)
0.0 0.7 GO:0008305 integrin complex(GO:0008305)
0.0 0.1 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 0.3 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.3 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.1 GO:0071818 BAT3 complex(GO:0071818)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.5 2.1 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.4 1.2 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.2 1.1 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.2 0.5 GO:0003994 aconitate hydratase activity(GO:0003994)
0.1 0.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 1.1 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.4 GO:0004020 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.1 0.4 GO:0004061 arylformamidase activity(GO:0004061)
0.1 0.7 GO:0070728 leucine binding(GO:0070728)
0.1 1.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.6 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.7 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 0.4 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 0.9 GO:0035925 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 0.6 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 2.0 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 0.3 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 1.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.5 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.5 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.8 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.3 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.1 0.9 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 0.4 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.8 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.6 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.2 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
0.0 0.3 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.3 GO:0030619 U1 snRNA binding(GO:0030619)
0.0 0.3 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.1 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.0 1.2 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.7 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 0.6 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 0.5 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.3 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.5 GO:0005123 death receptor binding(GO:0005123)
0.0 0.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.9 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.4 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 3.8 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.5 GO:0015379 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.0 0.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.7 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.3 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 2.0 GO:0101005 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 1.1 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 0.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.7 GO:0005178 integrin binding(GO:0005178)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.1 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0 0.2 GO:0031682 G-protein gamma-subunit binding(GO:0031682)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.6 PID PLK1 PATHWAY PLK1 signaling events
0.1 0.7 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 0.4 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.0 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.6 PID AURORA A PATHWAY Aurora A signaling
0.0 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.5 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.4 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.4 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.1 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.4 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.3 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.5 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.5 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.6 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 0.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 0.7 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 2.0 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.1 0.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 0.4 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.5 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.7 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.3 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.7 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.8 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.3 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.3 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.4 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.5 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.2 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.4 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.3 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.3 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase