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PRJNA195909:zebrafish embryo and larva development

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Results for wt1a+wt1b

Z-value: 1.44

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Transcription factors associated with wt1a+wt1b

Gene Symbol Gene ID Gene Info
ENSDARG00000007990 WT1 transcription factor b
ENSDARG00000031420 WT1 transcription factor a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
wt1adr11_v1_chr25_-_15214161_152141610.924.7e-04Click!
wt1bdr11_v1_chr18_-_45617146_456171460.781.2e-02Click!

Activity profile of wt1a+wt1b motif

Sorted Z-values of wt1a+wt1b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_47459723 3.78 ENSDART00000015046
follistatin-like 1a
chr15_+_1397811 3.42 ENSDART00000102125
schwannomin interacting protein 1
chr9_-_39005317 2.53 ENSDART00000014207
myosin, light chain 1, alkali; skeletal, fast
chr2_-_22535 2.39 ENSDART00000157877

chr12_-_16764751 2.34 ENSDART00000113862
zgc:174154
chr22_-_34872533 2.18 ENSDART00000167176
slit homolog 1b (Drosophila)
chr14_+_42172677 2.12 ENSDART00000148544
protocadherin 18b
chr19_+_1964005 2.00 ENSDART00000172049
SH3-domain binding protein 5a (BTK-associated)
chr14_+_42172257 1.91 ENSDART00000074362
protocadherin 18b
chr3_+_32526263 1.89 ENSDART00000150897
si:ch73-367p23.2
chr23_+_44732863 1.87 ENSDART00000160044
ENSDART00000172268
ATPase Na+/K+ transporting subunit beta 2a
chr13_+_25428677 1.65 ENSDART00000186284
si:dkey-51a16.9
chr17_-_125091 1.62 ENSDART00000158825
actin, alpha, cardiac muscle 1b
chr1_-_59571758 1.61 ENSDART00000193546
ENSDART00000167087
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1
chr20_-_40370736 1.60 ENSDART00000041229
fatty acid binding protein 7, brain, b
chr21_+_28958471 1.59 ENSDART00000144331
ENSDART00000005929
protein phosphatase 3, catalytic subunit, alpha isozyme
chr3_-_61162750 1.58 ENSDART00000055064
parvalbumin 8
chr11_-_97817 1.54 ENSDART00000092903
engulfment and cell motility 2
chr23_-_637347 1.53 ENSDART00000132175
L1 cell adhesion molecule, paralog b
chr6_+_6491013 1.51 ENSDART00000140827
B cell CLL/lymphoma 11Ab
chr19_+_48111285 1.46 ENSDART00000169420
NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 2
chr13_-_31435137 1.46 ENSDART00000057441
reticulon 1a
chr19_+_31771270 1.46 ENSDART00000147474
stathmin 2b
chr14_-_9522364 1.45 ENSDART00000054689
atonal bHLH transcription factor 8
chr10_-_28835771 1.44 ENSDART00000192220
ENSDART00000188436
activated leukocyte cell adhesion molecule a
chr5_+_9348284 1.40 ENSDART00000149417
T-cell acute lymphocytic leukemia 2
chr2_+_24304854 1.39 ENSDART00000078972
fat storage-inducing transmembrane protein 1
chr20_-_147574 1.38 ENSDART00000104762
ENSDART00000131635
solute carrier family 16 (aromatic amino acid transporter), member 10
chr25_+_192116 1.31 ENSDART00000153983
zgc:114188
chr11_-_32723851 1.31 ENSDART00000155592
protocadherin 17
chr17_+_30704068 1.31 ENSDART00000062793
apolipoprotein Ba
chr21_+_13861589 1.30 ENSDART00000015629
ENSDART00000171306
syntaxin binding protein 1a
chr8_-_46509194 1.30 ENSDART00000038924
sulfotransferase family 1, cytosolic sulfotransferase 1
chr21_+_38312549 1.27 ENSDART00000065159
zgc:158291
chr19_+_33701558 1.27 ENSDART00000147226
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr23_-_46201008 1.26 ENSDART00000160110
transglutaminase 1 like 4
chr11_+_329687 1.25 ENSDART00000172882
cytochrome P450, family 27, subfamily B, polypeptide 1
chr9_+_1654284 1.25 ENSDART00000062854
nuclear factor, erythroid 2-like 2a
chr13_-_36703164 1.23 ENSDART00000044357
cyclin-dependent kinase-like 1 (CDC2-related kinase)
chr18_-_15373620 1.22 ENSDART00000031752
regulatory factor X, 4
chr25_+_1732838 1.21 ENSDART00000159555
ENSDART00000168161
fibulin 1
chr1_-_53907092 1.20 ENSDART00000007732
calpain 9
chr20_-_9580446 1.20 ENSDART00000014168
zinc finger protein 36, C3H type-like 1b
chr16_-_53919115 1.19 ENSDART00000179533
frizzled class receptor 1
chr12_+_9880493 1.18 ENSDART00000055019
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4
chr12_+_47663419 1.17 ENSDART00000171932
hematopoietically expressed homeobox
chr3_+_32526799 1.16 ENSDART00000185755
si:ch73-367p23.2
chr3_+_32492467 1.14 ENSDART00000151329
transient receptor potential cation channel, subfamily M, member 4a
chr23_+_28731379 1.13 ENSDART00000047378
cortistatin
chr16_-_44399335 1.12 ENSDART00000165058
regulating synaptic membrane exocytosis 2a
chr11_+_10541258 1.12 ENSDART00000132365
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5a
chr19_+_30633453 1.11 ENSDART00000052124
family with sequence similarity 49, member A-like
chr7_+_73630751 1.11 ENSDART00000159745
si:dkey-46i9.1
chr25_-_18125769 1.11 ENSDART00000140484
kit ligand a
chr2_+_68789 1.10 ENSDART00000058569
claudin 1
chr21_+_11468934 1.10 ENSDART00000126045
ENSDART00000129744
ENSDART00000102368
glutamate receptor, ionotropic, N-methyl D-aspartate 1a
chr2_-_44183613 1.10 ENSDART00000079596
cell adhesion molecule 3
chr5_+_250078 1.09 ENSDART00000127504
TraB domain containing 2A
chr1_-_625875 1.09 ENSDART00000167331
amyloid beta (A4) precursor protein a
chr1_-_14234076 1.09 ENSDART00000040049
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2
chr10_+_10788811 1.09 ENSDART00000101077
ENSDART00000139143
prostaglandin D2 synthase a
chr8_-_9118958 1.08 ENSDART00000037922
solute carrier family 6 (neurotransmitter transporter), member 8
chr22_-_16180849 1.08 ENSDART00000090390
vascular cell adhesion molecule 1b
chr13_+_22480857 1.07 ENSDART00000078721
ENSDART00000044719
ENSDART00000130957
ENSDART00000078757
ENSDART00000130424
ENSDART00000078747
LIM domain binding 3a
chr4_+_1530287 1.07 ENSDART00000067446
solute carrier family 38, member 4
chr1_+_54908895 1.06 ENSDART00000145652
golgin A7 family, member Ba
chr13_+_13681681 1.05 ENSDART00000057825
complement factor D (adipsin)
chr1_-_51474974 1.05 ENSDART00000152719
sprouty-related, EVH1 domain containing 2a
chr1_-_14233815 1.05 ENSDART00000044896
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2
chr21_-_39058490 1.04 ENSDART00000114885
aldehyde dehydrogenase 3 family, member A2b
chr5_-_56513825 1.03 ENSDART00000024207
T-box 2a
chr7_-_51102479 1.01 ENSDART00000174023
collagen, type IV, alpha 6
chr8_+_54284961 1.01 ENSDART00000122692
plexin D1
chr21_+_6613772 0.99 ENSDART00000159645
procollagen, type V, alpha 1
chr20_+_26880668 0.99 ENSDART00000077769
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr10_+_45345574 0.99 ENSDART00000166085
peptidylprolyl isomerase Ab (cyclophilin A)
chr13_+_12739283 0.98 ENSDART00000102279
leucine rich repeat and Ig domain containing 2b
chr2_-_44183451 0.98 ENSDART00000111246
cell adhesion molecule 3
chr10_-_1718395 0.98 ENSDART00000137620
si:ch73-46j18.5
chr2_-_9646857 0.98 ENSDART00000056901
zgc:153615
chr21_-_22325124 0.97 ENSDART00000142100
glycerophosphodiester phosphodiesterase domain containing 4b
chr1_-_411331 0.97 ENSDART00000092524
RAS p21 protein activator 3
chr16_-_54405976 0.97 ENSDART00000055395
odd-skipped related transciption factor 2
chr17_+_53311618 0.97 ENSDART00000166517
ankyrin repeat and SOCS box containing 2b
chr25_+_5044780 0.96 ENSDART00000153980
parvin, beta
chr20_+_52554352 0.96 ENSDART00000153217
ENSDART00000145230
eukaryotic translation elongation factor 1 delta b (guanine nucleotide exchange protein)
chr11_+_2198831 0.96 ENSDART00000160515
homeobox C6b
chr3_-_1190132 0.95 ENSDART00000149709
single-pass membrane protein with aspartate-rich tail 1a
chr10_+_10351685 0.94 ENSDART00000109432
cerebral endothelial cell adhesion molecule
chr17_+_24615091 0.93 ENSDART00000064739
ribosomal protein L13a
chr1_-_25936677 0.93 ENSDART00000146488
ENSDART00000136321
myozenin 2b
chr16_-_2414063 0.92 ENSDART00000073621
zgc:152945
chr6_-_13408680 0.91 ENSDART00000151566
formin-like 2b
chr14_+_24283915 0.91 ENSDART00000172868
kelch-like family member 3
chr21_-_28901095 0.90 ENSDART00000180820
CXXC finger protein 5a
chr3_-_22829710 0.90 ENSDART00000055659
cytochrome b561
chr17_-_31695217 0.90 ENSDART00000104332
ENSDART00000143090
lin-52 DREAM MuvB core complex component
chr1_-_51157454 0.90 ENSDART00000047851
jagged 1a
chr16_+_10918252 0.88 ENSDART00000172949
POU class 2 homeobox 2a
chr5_+_36932718 0.88 ENSDART00000037879
cone-rod homeobox
chr1_-_59422880 0.87 ENSDART00000167244
si:ch211-188p14.2
chr6_+_39370587 0.87 ENSDART00000157165
ENSDART00000155079
si:dkey-195m11.8
chr14_-_12822 0.87 ENSDART00000180650
ENSDART00000188819
muscle segment homeobox 1a
chr23_+_42338325 0.86 ENSDART00000169660
cytochrome P450, family 2, subfamily AA, polypeptide 7
chr12_-_314899 0.86 ENSDART00000066579
6-pyruvoyltetrahydropterin synthase
chr17_+_52822422 0.86 ENSDART00000158273
ENSDART00000161414
Meis homeobox 2a
chr14_-_45346558 0.86 ENSDART00000090844
zgc:153018
chr6_-_18976168 0.85 ENSDART00000170039
septin 9b
chr19_-_31802296 0.85 ENSDART00000103640
hes-related family bHLH transcription factor with YRPW motif 1
chr3_+_12322170 0.83 ENSDART00000161227
GLIS family zinc finger 2b
chr17_-_43466317 0.82 ENSDART00000155313
heat shock protein 4 like
chr6_+_40629066 0.82 ENSDART00000103757
solute carrier family 6 (neurotransmitter transporter), member 11a
chr22_+_661711 0.82 ENSDART00000113795
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr5_+_64739762 0.82 ENSDART00000161112
ENSDART00000135610
ENSDART00000002908
olfactomedin 1a
chr3_+_50312422 0.80 ENSDART00000157689
growth arrest-specific 7a
chr14_-_413273 0.80 ENSDART00000163976
ENSDART00000179907
FAT atypical cadherin 4
chr7_-_18168493 0.79 ENSDART00000127428
pellino E3 ubiquitin protein ligase family member 3
chr3_+_14388010 0.79 ENSDART00000171726
ENSDART00000165452
transmembrane protein 56b
chr21_-_43117327 0.79 ENSDART00000122352
procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide 2
chr7_-_54677143 0.79 ENSDART00000163748
cyclin D1
chr21_-_22114625 0.78 ENSDART00000177426
ENSDART00000135410
ELMO/CED-12 domain containing 1
chr19_+_33701366 0.78 ENSDART00000162517
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr9_-_8454060 0.78 ENSDART00000110158
insulin receptor substrate 2b
chr24_-_4450238 0.77 ENSDART00000066835
frizzled class receptor 8a
chr18_-_3166726 0.76 ENSDART00000165002
aquaporin 11
chr11_+_11719575 0.76 ENSDART00000003891
junction plakoglobin a
chr12_+_5189776 0.75 ENSDART00000081298
leucine-rich, glioma inactivated 1b
chr25_-_37501371 0.75 ENSDART00000160498

chr6_+_59808677 0.75 ENSDART00000164469
calcium/calmodulin-dependent serine protein kinase b
chr9_+_21146862 0.74 ENSDART00000136365
hydroxyacid oxidase 2 (long chain)
chr24_+_3328354 0.74 ENSDART00000147468
3-hydroxybutyrate dehydrogenase, type 1
chr18_+_54354 0.74 ENSDART00000097163
zgc:158482
chr20_-_54462551 0.73 ENSDART00000171769
ENSDART00000169692
Enah/Vasp-like b
chr19_+_636886 0.73 ENSDART00000149192
telomerase reverse transcriptase
chr14_-_52552875 0.72 ENSDART00000170107
protein phosphatase 2, regulatory subunit B, beta a
chr20_-_54381034 0.72 ENSDART00000136779
ectonucleoside triphosphate diphosphohydrolase 5b
chr7_-_2090594 0.72 ENSDART00000183166
si:cabz01007802.1
chr10_+_32561317 0.71 ENSDART00000109029
microtubule-associated protein 6a
chr8_+_8298439 0.71 ENSDART00000170566
SRSF protein kinase 3
chr13_+_5570952 0.71 ENSDART00000134506
si:dkey-196j8.2
chr19_+_33701734 0.71 ENSDART00000123270
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr21_+_5801105 0.71 ENSDART00000151225
ENSDART00000184487
cyclin G2
chr1_+_59538755 0.70 ENSDART00000166354
Sp6 transcription factor
chr1_+_51475094 0.69 ENSDART00000146352
Meis homeobox 1 a
chr19_+_233143 0.69 ENSDART00000175273
synaptic Ras GTPase activating protein 1a
chr2_+_43469241 0.68 ENSDART00000142078
ENSDART00000098265
neuropilin 1b
chr3_+_7617353 0.68 ENSDART00000165551
zgc:109949
chr19_+_35799384 0.68 ENSDART00000076023
angiopoietin 2b
chr5_+_22969651 0.68 ENSDART00000089992
ENSDART00000145477
high mobility group nucleosomal binding domain 7
chr18_-_15467446 0.68 ENSDART00000187847
endonuclease, polyU-specific C
chr1_-_51734524 0.67 ENSDART00000109640
ENSDART00000122628
JunB proto-oncogene, AP-1 transcription factor subunit a
chr16_-_46766153 0.67 ENSDART00000115244
mex-3 RNA binding family member A
chr11_+_36989696 0.67 ENSDART00000045888
transketolase a
chr4_+_41602 0.67 ENSDART00000159640
putative homeodomain transcription factor 2
chr21_+_11468642 0.65 ENSDART00000041869
glutamate receptor, ionotropic, N-methyl D-aspartate 1a
chr15_-_42736433 0.65 ENSDART00000154379
si:ch211-181d7.1
chr17_-_20711735 0.65 ENSDART00000150056
ankyrin 3b
chr19_-_617246 0.65 ENSDART00000062551
cytochrome P450, family 51
chr7_+_48460239 0.64 ENSDART00000052113
leucine rich repeat and Ig domain containing 1b
chr8_-_53490376 0.64 ENSDART00000158789
choline dehydrogenase
chr1_+_37391141 0.64 ENSDART00000083593
ENSDART00000168647
SPARC-like 1
chr12_-_990149 0.64 ENSDART00000054367
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2b
chr16_+_36650984 0.64 ENSDART00000156780
collagen, type VI, alpha 4a
chr4_-_16001118 0.63 ENSDART00000041070
ENSDART00000125389
mesoderm specific transcript
chr16_+_6632969 0.63 ENSDART00000109276
spalt-like transcription factor 3a
chr23_+_44644911 0.62 ENSDART00000140799
zgc:85858
chr6_+_392815 0.62 ENSDART00000163142
cytohesin 4b
chr20_-_39517164 0.62 ENSDART00000175607
solute carrier family 35 member D3
chr8_-_52715911 0.61 ENSDART00000168241
tubulin, beta 2b
chr14_-_2602445 0.61 ENSDART00000166910
eukaryotic translation termination factor 1a
chr10_-_24343507 0.61 ENSDART00000002974
phosphatidylinositol transfer protein, alpha b
chr23_+_27912079 0.61 ENSDART00000171859

chr19_+_11985572 0.61 ENSDART00000130537
sperm associated antigen 1a
chr5_+_11840905 0.61 ENSDART00000030444
tescalcin a
chr3_-_62380146 0.61 ENSDART00000155853
G protein-coupled receptor, class C, group 5, member Ba
chr25_+_25464630 0.61 ENSDART00000150537
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7a
chr24_-_21258945 0.60 ENSDART00000111025
BOC cell adhesion associated, oncogene regulated
chr3_-_53722182 0.60 ENSDART00000032788
retinol dehydrogenase 8a
chr14_-_12837432 0.60 ENSDART00000178444
glutamate receptor, ionotropic, AMPA 3b
chr14_-_12837052 0.60 ENSDART00000165004
ENSDART00000043180
glutamate receptor, ionotropic, AMPA 3b
chr4_+_3980247 0.59 ENSDART00000049194
G protein-coupled receptor 37b
chr1_-_51157660 0.58 ENSDART00000137172
jagged 1a
chr22_-_600016 0.58 ENSDART00000086434
transmembrane and coiled-coil domain family 2
chr3_+_37787229 0.58 ENSDART00000075028
ribosomal protein S11
chr23_+_6752828 0.58 ENSDART00000105179
zgc:158254
chr15_-_8517555 0.58 ENSDART00000140213
neuronal PAS domain protein 1
chr13_+_13693722 0.57 ENSDART00000110509
si:ch211-194c3.5
chr1_-_38908197 0.57 ENSDART00000101489
vascular endothelial growth factor c
chr5_-_63109232 0.57 ENSDART00000115128
ubiquitin specific peptidase 2b
chr16_-_12316979 0.56 ENSDART00000182392
transient receptor potential cation channel, subfamily V, member 6
chr21_-_45878872 0.56 ENSDART00000029763
sap30-like
chr18_+_19772874 0.56 ENSDART00000043455
SMAD family member 3b
chr10_-_35542071 0.56 ENSDART00000162139
si:ch211-244c8.4
chr18_-_10298162 0.56 ENSDART00000007520
leucine rich repeat containing 4.2
chr6_-_60031693 0.55 ENSDART00000160275

chr22_+_10752511 0.55 ENSDART00000081188
LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated
chr24_+_24831727 0.55 ENSDART00000080969
tripartite motif containing 55b
chr16_+_12240605 0.55 ENSDART00000060056
triosephosphate isomerase 1b
chr11_+_6819050 0.55 ENSDART00000104289
RAB3A, member RAS oncogene family, b
chr1_+_55293424 0.54 ENSDART00000152464
zgc:172106

Network of associatons between targets according to the STRING database.

First level regulatory network of wt1a+wt1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.4 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.5 1.5 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.4 1.1 GO:0002369 T cell cytokine production(GO:0002369)
0.4 1.5 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.4 1.1 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.3 1.0 GO:0072068 distal convoluted tubule development(GO:0072025) late distal convoluted tubule development(GO:0072068)
0.3 0.9 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.3 1.3 GO:0006642 triglyceride mobilization(GO:0006642)
0.3 0.8 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531) eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
0.3 1.3 GO:0002159 desmosome assembly(GO:0002159)
0.2 0.7 GO:0007571 age-dependent general metabolic decline(GO:0007571)
0.2 0.6 GO:0019695 choline metabolic process(GO:0019695)
0.2 0.5 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.2 0.5 GO:0009085 lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878)
0.2 1.1 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.2 0.7 GO:0048014 Tie signaling pathway(GO:0048014)
0.2 0.5 GO:0001692 histamine metabolic process(GO:0001692)
0.2 1.0 GO:0038065 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.2 2.0 GO:0061099 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732) negative regulation of protein tyrosine kinase activity(GO:0061099)
0.2 0.5 GO:1904969 bleb assembly(GO:0032060) slow muscle cell migration(GO:1904969)
0.2 3.8 GO:0060034 notochord cell differentiation(GO:0060034)
0.2 0.8 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.2 0.8 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.2 0.5 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.2 1.2 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910)
0.1 0.4 GO:0032369 negative regulation of lipid transport(GO:0032369)
0.1 0.6 GO:0045023 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
0.1 0.6 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1 1.0 GO:0060855 venous endothelial cell migration involved in lymph vessel development(GO:0060855)
0.1 0.7 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.1 0.5 GO:0060092 regulation of synaptic transmission, glycinergic(GO:0060092)
0.1 0.5 GO:0002934 desmosome organization(GO:0002934)
0.1 0.4 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.1 1.2 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.1 0.6 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 0.3 GO:0098838 folic acid transport(GO:0015884) drug transport(GO:0015893) methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.1 0.5 GO:0060468 negative regulation of fertilization(GO:0060467) prevention of polyspermy(GO:0060468) cortical granule exocytosis(GO:0060471)
0.1 1.0 GO:0043363 nucleate erythrocyte differentiation(GO:0043363)
0.1 1.7 GO:0006584 catecholamine metabolic process(GO:0006584) catechol-containing compound metabolic process(GO:0009712)
0.1 1.9 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 1.9 GO:0036376 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.1 0.5 GO:0003210 cardiac atrium formation(GO:0003210)
0.1 0.6 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 1.5 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.1 0.8 GO:0061075 positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868)
0.1 0.4 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.1 2.0 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 0.5 GO:0045852 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.1 0.3 GO:0010812 negative regulation of cell-substrate adhesion(GO:0010812) negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 0.9 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 0.4 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
0.1 0.4 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 0.7 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.1 1.5 GO:0030878 thyroid gland development(GO:0030878)
0.1 0.2 GO:0030299 intestinal cholesterol absorption(GO:0030299)
0.1 0.4 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.1 0.8 GO:0039023 pronephric duct morphogenesis(GO:0039023)
0.1 0.6 GO:0006703 estrogen biosynthetic process(GO:0006703) estrogen metabolic process(GO:0008210)
0.1 1.4 GO:0019471 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.1 2.2 GO:0021602 cranial nerve morphogenesis(GO:0021602)
0.1 0.9 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.4 GO:0036268 swimming(GO:0036268)
0.1 1.3 GO:0018149 peptide cross-linking(GO:0018149)
0.1 0.9 GO:0043248 proteasome assembly(GO:0043248)
0.1 1.0 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.3 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.1 0.5 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 0.5 GO:0006868 glutamine transport(GO:0006868)
0.1 0.2 GO:0006843 mitochondrial citrate transport(GO:0006843)
0.1 1.0 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 0.5 GO:1904861 excitatory synapse assembly(GO:1904861)
0.1 0.6 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.4 GO:0021794 thalamus development(GO:0021794)
0.0 0.2 GO:0031649 heat generation(GO:0031649) regulation of heat generation(GO:0031650) positive regulation of heat generation(GO:0031652) regulation of phospholipid biosynthetic process(GO:0071071) negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0 0.5 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.2 GO:0006691 leukotriene metabolic process(GO:0006691) leukotriene biosynthetic process(GO:0019370)
0.0 0.5 GO:1902042 regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902041) negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.0 1.4 GO:0021514 ventral spinal cord interneuron differentiation(GO:0021514)
0.0 0.2 GO:0071387 cellular response to cortisol stimulus(GO:0071387)
0.0 0.7 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.0 1.6 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.9 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.7 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 1.6 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.4 GO:0021754 facial nucleus development(GO:0021754)
0.0 1.0 GO:0001569 patterning of blood vessels(GO:0001569)
0.0 0.5 GO:1900006 positive regulation of dendrite development(GO:1900006)
0.0 1.2 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 1.4 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.9 GO:0043049 otic placode formation(GO:0043049)
0.0 0.6 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.0 3.4 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 1.0 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.3 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.5 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.8 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.2 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.8 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 0.2 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.8 GO:0007586 digestion(GO:0007586)
0.0 0.1 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211) negative regulation of telomere maintenance via telomere lengthening(GO:1904357)
0.0 0.2 GO:0098971 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.0 0.1 GO:0032367 intracellular cholesterol transport(GO:0032367)
0.0 0.3 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0 1.1 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 1.1 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 1.7 GO:0001945 lymph vessel development(GO:0001945)
0.0 0.9 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 1.1 GO:0035567 non-canonical Wnt signaling pathway(GO:0035567)
0.0 0.7 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 1.4 GO:0002250 adaptive immune response(GO:0002250)
0.0 0.5 GO:0051289 protein homotetramerization(GO:0051289)
0.0 0.2 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.3 GO:0050890 cognition(GO:0050890)
0.0 4.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.4 GO:0046427 positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894)
0.0 0.6 GO:0001878 response to yeast(GO:0001878)
0.0 0.8 GO:0017144 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 2.7 GO:0008284 positive regulation of cell proliferation(GO:0008284)
0.0 0.6 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 0.9 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.1 GO:0071357 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 1.4 GO:0006909 phagocytosis(GO:0006909)
0.0 0.3 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.7 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.0 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.3 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.1 GO:0032288 myelin assembly(GO:0032288)
0.0 0.2 GO:0021772 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 1.0 GO:0042552 myelination(GO:0042552)
0.0 0.4 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.6 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.0 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.0 0.7 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.7 GO:0009948 anterior/posterior axis specification(GO:0009948)
0.0 0.3 GO:0042129 regulation of T cell proliferation(GO:0042129)
0.0 0.9 GO:0022900 electron transport chain(GO:0022900)
0.0 0.4 GO:0071711 basement membrane organization(GO:0071711)
0.0 0.2 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 1.7 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 0.4 GO:0046330 positive regulation of JNK cascade(GO:0046330)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:0005955 calcineurin complex(GO:0005955)
0.3 1.3 GO:0034359 mature chylomicron(GO:0034359)
0.2 1.0 GO:0005588 collagen type V trimer(GO:0005588)
0.2 0.7 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.2 1.9 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.2 1.0 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.2 1.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 1.0 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 2.1 GO:0005869 dynactin complex(GO:0005869)
0.1 0.8 GO:0070062 extracellular exosome(GO:0070062)
0.1 1.5 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.6 GO:0018444 translation release factor complex(GO:0018444)
0.1 0.4 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 1.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 1.0 GO:1990246 uniplex complex(GO:1990246)
0.1 0.9 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 1.4 GO:0005801 cis-Golgi network(GO:0005801)
0.1 1.4 GO:0030057 desmosome(GO:0030057)
0.1 0.8 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.5 GO:0014704 intercalated disc(GO:0014704)
0.0 1.6 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 3.6 GO:0030027 lamellipodium(GO:0030027)
0.0 0.1 GO:1990879 CST complex(GO:1990879)
0.0 0.9 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.0 0.5 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.3 GO:0002139 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142) stereocilium tip(GO:0032426)
0.0 0.6 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.5 GO:0043209 myelin sheath(GO:0043209)
0.0 0.5 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.4 GO:0030315 T-tubule(GO:0030315)
0.0 1.4 GO:0001725 stress fiber(GO:0001725) actomyosin(GO:0042641) contractile actin filament bundle(GO:0097517)
0.0 0.9 GO:0030426 growth cone(GO:0030426)
0.0 1.3 GO:0030018 Z disc(GO:0030018)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.1 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0033010 paranodal junction(GO:0033010)
0.0 0.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 1.0 GO:0030141 secretory granule(GO:0030141)
0.0 0.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.3 GO:0005840 ribosome(GO:0005840)
0.0 0.2 GO:0046658 anchored component of plasma membrane(GO:0046658)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.3 1.4 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.3 1.0 GO:0043185 vascular endothelial growth factor receptor 3 binding(GO:0043185)
0.3 0.9 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.3 1.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.3 1.6 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.2 0.7 GO:0003721 telomerase RNA reverse transcriptase activity(GO:0003721)
0.2 0.9 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.2 0.6 GO:0046923 ER retention sequence binding(GO:0046923)
0.2 0.6 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.2 1.8 GO:0045294 alpha-catenin binding(GO:0045294)
0.2 1.4 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.2 0.6 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1 1.3 GO:0070325 low-density lipoprotein particle receptor binding(GO:0050750) lipoprotein particle receptor binding(GO:0070325)
0.1 1.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 0.9 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 1.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 2.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.3 GO:0015350 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.1 0.7 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.1 1.6 GO:0005504 fatty acid binding(GO:0005504)
0.1 1.0 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 1.9 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.9 GO:0051373 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.1 0.4 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.1 0.4 GO:0016519 gastric inhibitory peptide receptor activity(GO:0016519)
0.1 1.8 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 0.3 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.3 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.1 0.6 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.4 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 1.1 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 1.0 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.1 1.2 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 2.0 GO:0004860 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.1 0.7 GO:0005522 profilin binding(GO:0005522)
0.1 0.6 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.9 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 1.3 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.1 1.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 1.0 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 1.5 GO:0005112 Notch binding(GO:0005112)
0.1 0.7 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 1.0 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 0.2 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 1.1 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1 0.6 GO:0005158 insulin receptor binding(GO:0005158)
0.1 0.5 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 0.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 1.5 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.4 GO:0016803 ether hydrolase activity(GO:0016803)
0.0 2.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.5 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.5 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.7 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 1.9 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 1.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 1.1 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.1 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.0 0.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.2 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.7 GO:0010181 FMN binding(GO:0010181)
0.0 1.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.5 GO:0048495 Roundabout binding(GO:0048495)
0.0 2.6 GO:0008201 heparin binding(GO:0008201)
0.0 0.5 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.3 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 1.1 GO:0005518 collagen binding(GO:0005518)
0.0 1.5 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.8 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.6 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.5 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.5 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.5 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.2 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.1 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.7 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.1 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.0 0.4 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.8 GO:0019209 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.0 0.9 GO:0005109 frizzled binding(GO:0005109)
0.0 0.4 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.2 GO:0055102 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.0 0.1 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.0 0.1 GO:0005351 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.2 GO:1990239 steroid hormone binding(GO:1990239)
0.0 1.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.0 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 14.3 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.2 GO:0015026 coreceptor activity(GO:0015026)
0.0 2.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 2.2 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.4 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 1.1 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 0.8 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 1.3 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.6 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.7 GO:0044325 ion channel binding(GO:0044325)
0.0 1.5 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.4 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.3 GO:0008483 transaminase activity(GO:0008483)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.6 GO:0005179 hormone activity(GO:0005179)
0.0 0.7 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 1.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 3.3 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 1.6 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 1.1 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 2.0 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.2 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.8 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.5 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 1.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.6 NABA SECRETED FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 0.9 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 1.1 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 3.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 0.9 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 1.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 2.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 0.5 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 1.0 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 0.8 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 0.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 1.3 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.6 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.5 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.5 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 2.0 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 0.3 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.6 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.8 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.9 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 1.5 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.8 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.7 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 1.2 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.2 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.5 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.1 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.5 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.5 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides