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PRJNA195909:zebrafish embryo and larva development

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Results for vsx2

Z-value: 0.33

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Transcription factors associated with vsx2

Gene Symbol Gene ID Gene Info
ENSDARG00000005574 visual system homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
vsx2dr11_v1_chr17_-_31659670_31659670-0.117.8e-01Click!

Activity profile of vsx2 motif

Sorted Z-values of vsx2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr21_-_13085242 0.32 ENSDART00000044504
zgc:109965
chr16_+_31804590 0.27 ENSDART00000167321
wingless-type MMTV integration site family, member 4b
chr16_+_46111849 0.27 ENSDART00000172232
synaptic vesicle glycoprotein 2A
chr21_-_37790727 0.26 ENSDART00000162907
gamma-aminobutyric acid (GABA) A receptor, beta 4
chr23_+_28731379 0.22 ENSDART00000047378
cortistatin
chr21_+_28958471 0.21 ENSDART00000144331
ENSDART00000005929
protein phosphatase 3, catalytic subunit, alpha isozyme
chr4_+_21129752 0.21 ENSDART00000169764
synaptotagmin Ia
chr24_-_21923930 0.20 ENSDART00000131944
transgelin 3b
chr20_+_35382482 0.19 ENSDART00000135284
visinin-like 1a
chr18_-_1185772 0.18 ENSDART00000143245
neuroplastin b
chr17_+_31185276 0.18 ENSDART00000062887
dispatched homolog 2 (Drosophila)
chr21_+_33172526 0.18 ENSDART00000183532
ADP-ribosylation factor-like 3, like 1
chr11_-_3865472 0.17 ENSDART00000161426
GATA binding protein 2a
chr9_+_11532025 0.16 ENSDART00000109037
cyclin-dependent kinase 5, regulatory subunit 2b (p39)
chr4_-_17629444 0.16 ENSDART00000108814
nuclear receptor interacting protein 2
chr21_+_6751405 0.16 ENSDART00000037265
ENSDART00000146371
olfactomedin 1b
chr1_-_19402802 0.15 ENSDART00000135552
RNA binding motif protein 47
chr21_+_6751760 0.15 ENSDART00000135914
olfactomedin 1b
chr21_+_25231160 0.14 ENSDART00000063089
ENSDART00000139127
guanine nucleotide binding protein (G protein), gamma 8
chr5_-_16996482 0.14 ENSDART00000144501
polypeptide N-acetylgalactosaminyltransferase 9
chr3_-_46817499 0.13 ENSDART00000013717
ELAV like neuron-specific RNA binding protein 3
chr14_+_25817628 0.13 ENSDART00000047680
glycine receptor, alpha 1
chr21_-_27185915 0.13 ENSDART00000135052
solute carrier family 8 (sodium/calcium exchanger), member 4a
chr9_-_5263947 0.12 ENSDART00000088342
cytohesin 1 interacting protein
chr12_-_35095414 0.12 ENSDART00000153229
si:dkey-21e13.3
chr15_-_22074315 0.12 ENSDART00000149830
dopamine receptor D2a
chr11_-_42554290 0.12 ENSDART00000130573
ATPase H+ transporting accessory protein 1 like a
chr2_-_35566938 0.11 ENSDART00000029006
ENSDART00000077178
ENSDART00000125298
tenascin N
chr22_-_20011476 0.11 ENSDART00000093312
ENSDART00000093310
cugbp, Elav-like family member 5a
chr23_+_28582865 0.11 ENSDART00000020296
L1 cell adhesion molecule, paralog a
chr8_+_18588551 0.10 ENSDART00000177476
ENSDART00000063539
proline rich Gla (G-carboxyglutamic acid) 1
chr11_+_38280454 0.10 ENSDART00000171496
si:dkey-166c18.1
chr20_-_9436521 0.10 ENSDART00000133000
zgc:101840
chr19_+_22062202 0.09 ENSDART00000100181
spalt-like transcription factor 3b
chr8_-_15129573 0.09 ENSDART00000142358
BCAR3, NSP family adaptor protein
chr13_-_42560662 0.09 ENSDART00000124898

chr24_-_23320223 0.09 ENSDART00000135846
zinc finger homeobox 4
chr25_-_16057539 0.09 ENSDART00000090388
cytochrome b5 reductase 2
chr5_-_64831207 0.09 ENSDART00000144816
limb and CNS expressed 1
chr18_+_28106139 0.09 ENSDART00000089615
KIAA1549-like b
chr4_-_20292821 0.08 ENSDART00000136069
ENSDART00000192504
calcium channel, voltage-dependent, alpha 2/delta subunit 4a
chr13_-_44630111 0.08 ENSDART00000110092
MAM domain containing glycosylphosphatidylinositol anchor 1
chr15_-_16098531 0.08 ENSDART00000080377
aldolase C, fructose-bisphosphate, a
chr18_-_2433011 0.08 ENSDART00000181922
ENSDART00000193276

chr24_+_35881124 0.07 ENSDART00000143015
kelch-like family member 14
chr20_-_46362606 0.07 ENSDART00000153087
BCL2 modifying factor 2
chr23_-_19230627 0.07 ENSDART00000007122
guanylate cyclase activator 1B
chr11_-_37425407 0.06 ENSDART00000160911
ELKS/RAB6-interacting/CAST family member 2
chr4_+_3980247 0.06 ENSDART00000049194
G protein-coupled receptor 37b
chr21_+_32820175 0.06 ENSDART00000076903
adrenergic, alpha-2D-, receptor b
chr9_+_50001746 0.06 ENSDART00000058892
solute carrier family 38, member 11
chr22_-_13350240 0.06 ENSDART00000154095
ENSDART00000155118
si:ch211-227m13.1
chr24_-_6078222 0.06 ENSDART00000146830
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr5_-_48268049 0.05 ENSDART00000187454
myocyte enhancer factor 2cb
chr3_-_43356082 0.05 ENSDART00000171213
UNC homeobox
chr20_+_37294112 0.05 ENSDART00000076293
ENSDART00000140450
connexin 23
chr13_+_19322686 0.05 ENSDART00000058036
empty spiracles homeobox 2
chr14_+_40874608 0.05 ENSDART00000168448
si:ch211-106m9.1
chr3_-_46811611 0.04 ENSDART00000134092
ELAV like neuron-specific RNA binding protein 3
chr18_+_14529005 0.04 ENSDART00000186379
potassium voltage-gated channel, subfamily G, member 4a
chr17_+_3379673 0.04 ENSDART00000176354
syntrophin, gamma 2
chr23_+_23658474 0.04 ENSDART00000162838
agrin
chr23_-_24483311 0.04 ENSDART00000185793
ENSDART00000109248
spen family transcriptional repressor
chr11_+_18873113 0.04 ENSDART00000103969
ENSDART00000103968
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr8_+_20776654 0.03 ENSDART00000135850
nuclear factor I/C
chr11_+_18873619 0.03 ENSDART00000176141
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr12_+_20352400 0.03 ENSDART00000066383
hemoglobin, alpha embryonic 5
chr5_-_28109416 0.03 ENSDART00000042002
si:ch211-48m9.1
chr23_-_24195519 0.03 ENSDART00000112370
ENSDART00000180377
anoctamin 11
chr3_+_17537352 0.02 ENSDART00000104549
hypocretin (orexin) neuropeptide precursor
chr23_-_24195723 0.02 ENSDART00000145489
anoctamin 11
chr7_-_4315859 0.02 ENSDART00000172762
si:ch211-63p21.8
chr18_-_24989580 0.02 ENSDART00000163449
chromodomain helicase DNA binding protein 2
chr15_+_5360407 0.02 ENSDART00000110420
odorant receptor, family A, subfamily 112, member 1
chr12_-_19862912 0.02 ENSDART00000145788
shisa family member 9a
chr24_-_35282568 0.01 ENSDART00000167406
ENSDART00000088609
syntrophin, gamma 1
chr5_+_5398966 0.01 ENSDART00000139553
mitogen-activated protein kinase associated protein 1
chr1_-_17715493 0.00 ENSDART00000133027
si:dkey-256e7.8
chr15_-_9272328 0.00 ENSDART00000172114
calmodulin 2a (phosphorylase kinase, delta)
chr10_+_42423318 0.00 ENSDART00000134282
neuropeptide Y receptor Y8a
chr13_+_35637048 0.00 ENSDART00000085037
thrombospondin 2a
chr1_+_55755304 0.00 ENSDART00000144983
trans-2,3-enoyl-CoA reductase b

Network of associatons between targets according to the STRING database.

First level regulatory network of vsx2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:1902895 pri-miRNA transcription from RNA polymerase II promoter(GO:0061614) regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902893) positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.0 0.1 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.2 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.0 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
0.0 0.1 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.0 0.1 GO:0042044 fluid transport(GO:0042044)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.2 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.1 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.1 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events