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PRJNA195909:zebrafish embryo and larva development

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Results for tlx1

Z-value: 1.05

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Transcription factors associated with tlx1

Gene Symbol Gene ID Gene Info
tlx1
ENSDARG00000003965 T cell leukemia homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
tlx1dr11_v1_chr13_-_28272299_282722990.835.9e-03Click!

Activity profile of tlx1 motif

Sorted Z-values of tlx1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_30404096 2.36 ENSDART00000103475
agr2
anterior gradient 2
chr2_+_55982940 2.22 ENSDART00000097753
ENSDART00000097751
nmrk2
nicotinamide riboside kinase 2
chr19_-_30403922 1.92 ENSDART00000181841
agr2
anterior gradient 2
chr20_+_10545514 1.90 ENSDART00000153667
serpina1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr20_+_10539293 1.90 ENSDART00000182265
serpina1l
serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1, like
chr17_+_52822422 1.78 ENSDART00000158273
ENSDART00000161414
meis2a
Meis homeobox 2a
chr9_-_22831836 1.77 ENSDART00000142585
neb
nebulin
chr20_+_16750177 1.76 ENSDART00000185357
calm1b
calmodulin 1b
chr22_+_22888 1.70 ENSDART00000082471
mfap2
microfibril associated protein 2
chr12_+_27127139 1.61 ENSDART00000025966
hoxb6b
homeobox B6b
chr1_-_58059134 1.54 ENSDART00000160970
caspb
caspase b
chr1_+_4101741 1.52 ENSDART00000163793
slitrk6
SLIT and NTRK-like family, member 6
chr16_+_23397785 1.47 ENSDART00000148961
s100a10b
S100 calcium binding protein A10b
chr1_+_49568335 1.42 ENSDART00000142957
col17a1a
collagen, type XVII, alpha 1a
chr7_-_35126374 1.40 ENSDART00000141211
hsd11b2
hydroxysteroid (11-beta) dehydrogenase 2
chr17_+_52822831 1.38 ENSDART00000193368
meis2a
Meis homeobox 2a
chr7_+_14291323 1.38 ENSDART00000053521
rhcga
Rh family, C glycoprotein a
chr19_+_9004256 1.31 ENSDART00000186401
ENSDART00000091443
si:ch211-81a5.1
si:ch211-81a5.1
chr22_+_38229321 1.24 ENSDART00000132670
ENSDART00000104504
si:ch211-284e20.8
si:ch211-284e20.8
chr4_-_16406737 1.21 ENSDART00000013085
dcn
decorin
chr17_+_37645633 1.19 ENSDART00000085500
tmem229b
transmembrane protein 229B
chr22_+_11857356 1.18 ENSDART00000179540
mras
muscle RAS oncogene homolog
chr2_-_8017579 1.16 ENSDART00000040209
ephb3a
eph receptor B3a
chr9_-_34296406 1.15 ENSDART00000125451
ildr2
immunoglobulin-like domain containing receptor 2
chr20_+_34320635 1.14 ENSDART00000153207
ivns1abpa
influenza virus NS1A binding protein a
chr1_-_22757145 1.13 ENSDART00000134719
prom1b
prominin 1 b
chr3_-_5664123 1.10 ENSDART00000145866
si:ch211-106h11.1
si:ch211-106h11.1
chr13_-_9895564 1.06 ENSDART00000169831
ENSDART00000142629
si:ch211-117n7.6
si:ch211-117n7.6
chr6_-_13114406 1.05 ENSDART00000188015
zgc:194469
zgc:194469
chr7_-_24472991 1.04 ENSDART00000121684
nat8l
N-acetyltransferase 8-like
chr24_+_25692802 1.02 ENSDART00000190493
camk2n2
calcium/calmodulin-dependent protein kinase II inhibitor 2
chr19_+_30388186 0.98 ENSDART00000103474
tspan13b
tetraspanin 13b
chr17_+_38262408 0.94 ENSDART00000017493
nkx2.1
NK2 homeobox 1
chr5_-_57655092 0.90 ENSDART00000074290
mia
melanoma inhibitory activity
chr6_-_35401282 0.90 ENSDART00000127612
rgs5a
regulator of G protein signaling 5a
chr6_-_49673476 0.89 ENSDART00000112226
apcdd1l
adenomatosis polyposis coli down-regulated 1-like
chr8_-_16712111 0.88 ENSDART00000184147
ENSDART00000180419
ENSDART00000076600
rpe65c
retinal pigment epithelium-specific protein 65c
chr8_+_41647539 0.87 ENSDART00000136492
ENSDART00000138799
ENSDART00000134404
si:ch211-158d24.4
si:ch211-158d24.4
chr3_+_57038033 0.82 ENSDART00000162930
bahcc1a
BAH domain and coiled-coil containing 1a
chr6_+_53349966 0.82 ENSDART00000167079
si:ch211-161c3.5
si:ch211-161c3.5
chr7_+_57109214 0.79 ENSDART00000135068
ENSDART00000098412
enosf1
enolase superfamily member 1
chr23_-_45504991 0.78 ENSDART00000148761
col24a1
collagen type XXIV alpha 1
chr10_-_17232372 0.78 ENSDART00000135679
rab36
RAB36, member RAS oncogene family
chr17_+_52823015 0.75 ENSDART00000160507
ENSDART00000186979
meis2a
Meis homeobox 2a
chr4_+_74131530 0.74 ENSDART00000174125
CABZ01072523.1

chr22_-_11438627 0.73 ENSDART00000007649
mid1ip1b
MID1 interacting protein 1b
chr1_+_10297027 0.73 ENSDART00000152562
eif3f
eukaryotic translation initiation factor 3, subunit F
chr2_-_17827983 0.73 ENSDART00000166518
ptprfb
protein tyrosine phosphatase, receptor type, f, b
chr21_-_34658266 0.70 ENSDART00000023038
dacha
dachshund a
chr9_-_24242592 0.68 ENSDART00000039399
cavin2a
caveolae associated protein 2a
chr6_-_34006917 0.67 ENSDART00000190702
ENSDART00000184003
tie1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr1_-_22756898 0.64 ENSDART00000158915
prom1b
prominin 1 b
chr8_-_53108207 0.63 ENSDART00000111023
b3galt4
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
chr11_+_38332419 0.63 ENSDART00000005864
CDK18
si:dkey-166c18.1
chr13_+_28761998 0.63 ENSDART00000146581
prom2
prominin 2
chr1_-_28629471 0.63 ENSDART00000121758
ednrba
endothelin receptor Ba
chr23_-_20100436 0.62 ENSDART00000143445
si:dkey-32e6.6
si:dkey-32e6.6
chr3_+_24482999 0.60 ENSDART00000059179
nptxra
neuronal pentraxin receptor a
chr15_-_34892664 0.54 ENSDART00000153787
ENSDART00000099721
rnf183
ring finger protein 183
chr11_+_37265692 0.51 ENSDART00000184691
il17rc
interleukin 17 receptor C
chr8_-_34052019 0.50 ENSDART00000040126
ENSDART00000159208
ENSDART00000048994
ENSDART00000098822
pbx3b
pre-B-cell leukemia homeobox 3b
chr11_+_14284866 0.50 ENSDART00000163729
si:ch211-262i1.3
si:ch211-262i1.3
chr12_+_35654749 0.49 ENSDART00000169889
ENSDART00000167873
baiap2b
BAI1-associated protein 2b
chr18_-_39473055 0.49 ENSDART00000122930
scg3
secretogranin III
chr17_-_22067451 0.49 ENSDART00000156872
ttbk1b
tau tubulin kinase 1b
chr16_+_14029283 0.49 ENSDART00000146165
ENSDART00000132075
rusc1
RUN and SH3 domain containing 1
chr13_-_31829786 0.49 ENSDART00000138667
sertad4
SERTA domain containing 4
chr2_-_21618629 0.48 ENSDART00000027587
ralab
v-ral simian leukemia viral oncogene homolog Ab (ras related)
chr13_-_32577386 0.47 ENSDART00000016535
kcns3a
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3a
chr7_-_22132265 0.46 ENSDART00000125284
ENSDART00000112978
nlgn2a
neuroligin 2a
chr11_-_34147205 0.43 ENSDART00000173216
atp13a3
ATPase 13A3
chr9_-_25089536 0.42 ENSDART00000143479
rubcnl
RUN and cysteine rich domain containing beclin 1 interacting protein like
chr5_-_16218777 0.42 ENSDART00000141698
kremen1
kringle containing transmembrane protein 1
chr9_-_23358597 0.42 ENSDART00000046423
arl4cb
ADP-ribosylation factor-like 4Cb
chr1_-_56363108 0.41 ENSDART00000021878
gcgrb
glucagon receptor b
chr9_-_44939104 0.40 ENSDART00000192903
vil1
villin 1
chr4_+_61171310 0.38 ENSDART00000141738
si:dkey-9p20.18
si:dkey-9p20.18
chr7_-_52096498 0.38 ENSDART00000098688
ENSDART00000098690
cyp2x10.2
cytochrome P450, family 2, subfamily X, polypeptide 10.2
chr20_-_26066020 0.38 ENSDART00000078559
myct1a
myc target 1a
chr20_+_54383838 0.36 ENSDART00000157737
lrfn5b
leucine rich repeat and fibronectin type III domain containing 5b
chr13_+_23162447 0.36 ENSDART00000180209
sorbs1
sorbin and SH3 domain containing 1
chr6_-_21873266 0.36 ENSDART00000151658
ENSDART00000151152
ENSDART00000151179
si:dkey-19e4.5
si:dkey-19e4.5
chr13_+_37040789 0.36 ENSDART00000063412
esr2b
estrogen receptor 2b
chr4_-_64709908 0.35 ENSDART00000161032
si:dkey-9i5.2
si:dkey-9i5.2
chr24_-_21819010 0.35 ENSDART00000091096
CR352265.1

chr6_+_39184236 0.34 ENSDART00000156187
tac3b
tachykinin 3b
chr4_-_38033800 0.33 ENSDART00000159662
si:dkeyp-82b4.4
si:dkeyp-82b4.4
chr17_-_45040813 0.33 ENSDART00000075514
entpd5a
ectonucleoside triphosphate diphosphohydrolase 5a
chr24_+_7884880 0.33 ENSDART00000139467
bmp6
bone morphogenetic protein 6
chr7_-_41468751 0.33 ENSDART00000150146
smarcd3b
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3b
chr6_+_28141135 0.32 ENSDART00000113405
ENSDART00000179795
inpp5d
inositol polyphosphate-5-phosphatase D
chr2_-_59303338 0.31 ENSDART00000100987
ENSDART00000140840
ftr35
finTRIM family, member 35
chr15_-_14469704 0.31 ENSDART00000185077
numbl
numb homolog (Drosophila)-like
chr10_+_7636811 0.29 ENSDART00000160673
hint1
histidine triad nucleotide binding protein 1
chr9_+_16449398 0.28 ENSDART00000006787
epha3
eph receptor A3
chr21_-_2707768 0.27 ENSDART00000165384
CABZ01101739.1

chr2_-_59285085 0.27 ENSDART00000131880
ftr34
finTRIM family, member 34
chr10_+_8091144 0.25 ENSDART00000143848
ENSDART00000075485
sub1a
SUB1 homolog, transcriptional regulator a
chr17_-_22048233 0.24 ENSDART00000155203
ttbk1b
tau tubulin kinase 1b
chr2_-_53925308 0.23 ENSDART00000190705
FO834855.1

chr11_+_24251141 0.23 ENSDART00000182684
pnp4a
purine nucleoside phosphorylase 4a
chr6_+_2951645 0.23 ENSDART00000183181
ENSDART00000181271
ptprfa
protein tyrosine phosphatase, receptor type, f, a
chr2_-_59285407 0.22 ENSDART00000181616
ftr34
finTRIM family, member 34
chr20_-_33976305 0.19 ENSDART00000111022
sele
selectin E
chr16_+_16849220 0.18 ENSDART00000047409
ENSDART00000142155
myh14
myosin, heavy chain 14, non-muscle
chr7_+_52135791 0.17 ENSDART00000098705
cyp2x12
cytochrome P450, family 2, subfamily X, polypeptide 12
chr8_+_53423408 0.17 ENSDART00000164792
cacna1db
calcium channel, voltage-dependent, L type, alpha 1D subunit, b
chr18_-_2433011 0.16 ENSDART00000181922
ENSDART00000193276
CR769778.1

chr15_-_18091157 0.15 ENSDART00000153848
phldb1b
pleckstrin homology-like domain, family B, member 1b
chr20_-_20410029 0.15 ENSDART00000192177
ENSDART00000063483
prkchb
protein kinase C, eta, b
chr4_-_58448785 0.14 ENSDART00000172359
si:ch211-212k5.3
si:ch211-212k5.3
chr12_-_37941733 0.14 ENSDART00000130167
CABZ01046949.1

chr6_+_41957280 0.12 ENSDART00000050114
oxtr
oxytocin receptor
chr5_+_35502290 0.11 ENSDART00000191222
CR762390.1

chr13_-_41482064 0.11 ENSDART00000188322
ENSDART00000164732
pcdh15a
protocadherin-related 15a
chr6_+_28140816 0.11 ENSDART00000137907
inpp5d
inositol polyphosphate-5-phosphatase D
chr3_-_37681824 0.11 ENSDART00000185858
gpatch8
G patch domain containing 8
chr6_+_26346686 0.10 ENSDART00000154183
dzip1l
DAZ interacting zinc finger protein 1-like
chr20_+_48739154 0.10 ENSDART00000100262
zgc:110348
zgc:110348
chr3_+_33918510 0.09 ENSDART00000055248
alkbh7
alkB homolog 7
chr20_-_2134620 0.07 ENSDART00000064375
tmem244
transmembrane protein 244
chr3_-_40528333 0.07 ENSDART00000193047
actb2
actin, beta 2
chr4_-_51460013 0.07 ENSDART00000193382
CR628395.1

chr7_+_57108823 0.07 ENSDART00000184943
ENSDART00000055956
enosf1
enolase superfamily member 1
chr17_-_31308658 0.06 ENSDART00000124505
bahd1
bromo adjacent homology domain containing 1
chr7_-_51953807 0.06 ENSDART00000174102
ENSDART00000145645
ENSDART00000052054
cyp2x10.2
cytochrome P450, family 2, subfamily X, polypeptide 10.2
chr15_-_38202630 0.05 ENSDART00000183772
rhoga
ras homolog family member Ga
chr5_-_57526807 0.04 ENSDART00000022866
pisd
phosphatidylserine decarboxylase
chr3_+_61391636 0.04 ENSDART00000126417
bri3
brain protein I3
chr10_-_15672862 0.01 ENSDART00000109231
mamdc2b
MAM domain containing 2b
chr23_-_18572685 0.01 ENSDART00000047175
ssr4
signal sequence receptor, delta
chr17_-_7496341 0.01 ENSDART00000186907
si:ch211-278p9.3
si:ch211-278p9.3
chr19_+_22727940 0.00 ENSDART00000052509
trhrb
thyrotropin-releasing hormone receptor b
chr12_-_36521947 0.00 ENSDART00000152946
unc13d
unc-13 homolog D (C. elegans)

Network of associatons between targets according to the STRING database.

First level regulatory network of tlx1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.3 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.3 1.8 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.2 0.9 GO:0016108 tetraterpenoid metabolic process(GO:0016108) tetraterpenoid biosynthetic process(GO:0016109) carotenoid metabolic process(GO:0016116) carotenoid biosynthetic process(GO:0016117) xanthophyll metabolic process(GO:0016122) xanthophyll biosynthetic process(GO:0016123) zeaxanthin metabolic process(GO:1901825) zeaxanthin biosynthetic process(GO:1901827)
0.2 1.1 GO:0006660 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.2 1.4 GO:0034650 cortisol metabolic process(GO:0034650)
0.2 1.4 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.1 0.8 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.1 1.2 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 1.0 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.1 0.4 GO:2000392 lamellipodium morphogenesis(GO:0072673) regulation of lamellipodium morphogenesis(GO:2000392)
0.1 0.3 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.1 0.4 GO:0048903 anterior lateral line neuromast hair cell differentiation(GO:0048903)
0.1 0.7 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.1 0.3 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 0.4 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.1 5.0 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.1 1.8 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 0.5 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.5 GO:0097090 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.0 1.5 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.0 0.1 GO:0021985 parturition(GO:0007567) neurohypophysis development(GO:0021985) multi-multicellular organism process(GO:0044706) maternal process involved in parturition(GO:0060137)
0.0 3.9 GO:0009880 embryonic pattern specification(GO:0009880)
0.0 0.3 GO:0031498 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 1.2 GO:0050654 chondroitin sulfate proteoglycan metabolic process(GO:0050654)
0.0 0.4 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)
0.0 0.3 GO:0055062 phosphate ion homeostasis(GO:0055062) trivalent inorganic anion homeostasis(GO:0072506)
0.0 0.6 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.6 GO:0050935 iridophore differentiation(GO:0050935)
0.0 0.9 GO:0021854 hypothalamus development(GO:0021854)
0.0 1.7 GO:0048048 embryonic eye morphogenesis(GO:0048048)
0.0 1.2 GO:0007492 endoderm development(GO:0007492)
0.0 0.7 GO:0072175 epithelial tube formation(GO:0072175)
0.0 0.1 GO:2000144 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 1.0 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.0 0.7 GO:0018108 peptidyl-tyrosine phosphorylation(GO:0018108)
0.0 1.5 GO:0008544 epidermis development(GO:0008544)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0061702 inflammasome complex(GO:0061702)
0.3 2.4 GO:0071914 prominosome(GO:0071914)
0.3 0.8 GO:0005592 collagen type XI trimer(GO:0005592)
0.2 0.7 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.2 0.5 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.4 GO:0032433 filopodium tip(GO:0032433)
0.0 1.0 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.5 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 1.8 GO:0030018 Z disc(GO:0030018)
0.0 0.7 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.1 GO:0097433 dense body(GO:0097433)
0.0 0.4 GO:0000421 autophagosome membrane(GO:0000421)
0.0 1.1 GO:0044420 extracellular matrix component(GO:0044420)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.2 0.9 GO:0052885 retinol isomerase activity(GO:0050251) all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity(GO:0052885)
0.2 1.0 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.2 0.6 GO:0070052 collagen V binding(GO:0070052)
0.1 1.5 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.1 0.6 GO:0004962 endothelin receptor activity(GO:0004962)
0.1 1.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.4 GO:0016519 gastric inhibitory peptide receptor activity(GO:0016519)
0.1 1.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 1.4 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0033764)
0.1 0.4 GO:1903924 estradiol binding(GO:1903924)
0.1 1.4 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 1.5 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 0.4 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 2.4 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.5 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 1.5 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0004990 oxytocin receptor activity(GO:0004990)
0.0 0.7 GO:0070122 isopeptidase activity(GO:0070122)
0.0 0.7 GO:0005080 protein kinase C binding(GO:0005080)
0.0 1.2 GO:0005518 collagen binding(GO:0005518)
0.0 3.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0070700 BMP receptor binding(GO:0070700)
0.0 1.2 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 4.3 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 0.9 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.3 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 2.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.6 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 2.3 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.1 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.0 0.9 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 1.0 GO:0008080 N-acetyltransferase activity(GO:0008080)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.3 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.0 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.3 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.4 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.2 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.4 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.4 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 1.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 2.4 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.4 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 0.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse