ISMARA results: thrb

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PRJNA195909:zebrafish embryo and larva development

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Results for thrb

Z-value: 0.35

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Transcription factors associated with thrb

Gene Symbol	Gene ID	Gene Info
thrb NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000021163	thyroid hormone receptor beta

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
thrb	dr11_v1_chr19_-_17526735_17526735	0.60	8.8e-02	Click!

Activity profile of thrb motif

Sorted Z-values of thrb motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr15_-_23645810 Show fit	1.52	ENSDART00000168845	ckmb NCBI UniProt ZFIN ENSEMBL Google Show fit	creatine kinase, muscle b
chr23_+_36653376 Show fit	0.74	ENSDART00000053189	gpr182 NCBI UniProt ZFIN ENSEMBL Google Show fit	G protein-coupled receptor 182
chr22_-_2886937 Show fit	0.71	ENSDART00000063533	aqp12 NCBI UniProt ZFIN ENSEMBL Google Show fit	aquaporin 12
chr13_-_22862133 Show fit	0.61	ENSDART00000138563	pbld2 NCBI UniProt ZFIN ENSEMBL Google Show fit	phenazine biosynthesis-like protein domain containing 2
chr5_+_38673168 Show fit	0.37	ENSDART00000135267	si:dkey-58f10.12 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-58f10.12
chr2_+_10766744 Show fit	0.28	ENSDART00000015379	gfi1aa NCBI UniProt ZFIN ENSEMBL Google Show fit	growth factor independent 1A transcription repressor a
chr13_-_9318891 Show fit	0.27	ENSDART00000137364	si:dkey-33c12.3 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-33c12.3
chr11_-_42980535 Show fit	0.22	ENSDART00000181160 ENSDART00000192064	CABZ01069998.1 NCBI UniProt ZFIN ENSEMBL Google Show fit
chr2_-_5199431 Show fit	0.20	ENSDART00000063384	phb2a NCBI UniProt ZFIN ENSEMBL Google Show fit	prohibitin 2a
chr5_+_28797771 Show fit	0.17	ENSDART00000188845 ENSDART00000149066	si:ch211-186e20.7 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-186e20.7
chr7_-_8014186 Show fit	0.12	ENSDART00000190012	si:cabz01030277.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:cabz01030277.1
chr7_-_8156169 Show fit	0.10	ENSDART00000182960 ENSDART00000190184 ENSDART00000190885 ENSDART00000189867 ENSDART00000160836	si:cabz01030277.1 NCBI UniProt ZFIN ENSEMBL Google Show fit si:ch211-163c2.3 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:cabz01030277.1 si:ch211-163c2.3
chr19_-_32804535 Show fit	0.10	ENSDART00000175613 ENSDART00000052098	nt5c1aa NCBI UniProt ZFIN ENSEMBL Google Show fit	5'-nucleotidase, cytosolic IAa
chr6_-_51556308 Show fit	0.05	ENSDART00000149033	rbl1 NCBI UniProt ZFIN ENSEMBL Google Show fit	retinoblastoma-like 1 (p107)
chr5_-_58832332 Show fit	0.04	ENSDART00000161230	arhgef12b NCBI UniProt ZFIN ENSEMBL Google Show fit	Rho guanine nucleotide exchange factor (GEF) 12b
chr24_-_1023112 Show fit	0.00	ENSDART00000147508 ENSDART00000066863	ralaa NCBI UniProt ZFIN ENSEMBL Google Show fit	v-ral simian leukemia viral oncogene homolog Aa (ras related)

Network of associatons between targets according to the STRING database.

First level regulatory network of thrb

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.5	GO:0006603	phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.0	0.2	GO:0070212	protein poly-ADP-ribosylation(GO:0070212)
0.0	0.7	GO:0071391	cellular response to estrogen stimulus(GO:0071391)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.5	GO:0016775	creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.0	0.2	GO:1990404	protein ADP-ribosylase activity(GO:1990404)