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PRJNA195909:zebrafish embryo and larva development

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Results for tfcp2+tfcp2l1+ubp1

Z-value: 1.37

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Transcription factors associated with tfcp2+tfcp2l1+ubp1

Gene Symbol Gene ID Gene Info
ENSDARG00000018000 upstream binding protein 1
ENSDARG00000029497 transcription factor CP2-like 1
ENSDARG00000060306 transcription factor CP2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
tfcp2l1dr11_v1_chr9_+_38292947_38292947-0.432.5e-01Click!
ubp1dr11_v1_chr19_+_42806812_42806814-0.049.2e-01Click!
tfcp2dr11_v1_chr23_-_33680265_336802650.049.2e-01Click!

Activity profile of tfcp2+tfcp2l1+ubp1 motif

Sorted Z-values of tfcp2+tfcp2l1+ubp1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_68795063 2.06 ENSDART00000016307
hairy-related 1
chr22_+_22021936 1.51 ENSDART00000149586
guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 1
chr10_-_15048781 1.29 ENSDART00000038401
ENSDART00000155674
si:ch211-95j8.2
chr13_+_18533005 1.26 ENSDART00000136024
finTRIM family, member 14-like
chr7_-_38792543 1.10 ENSDART00000157416
si:dkey-23n7.10
chr13_+_28495419 1.06 ENSDART00000025583
fibroblast growth factor 8a
chr3_-_27647845 1.04 ENSDART00000151625
si:ch211-157c3.4
chr4_-_48636872 1.03 ENSDART00000168605
zinc finger protein 1063
chr17_+_51743908 1.00 ENSDART00000149039
ENSDART00000148869
ornithine decarboxylase 1
chr24_+_38671054 0.96 ENSDART00000154214
si:ch73-70c5.1
chr12_-_7607114 0.93 ENSDART00000158095
solute carrier family 16, member 9b
chr15_-_601971 0.92 ENSDART00000188882
arachidonate 5-lipoxygenase b, tandem duplicate 3
chr16_-_6424816 0.91 ENSDART00000164864
ENSDART00000141860
membrane bound O-acyltransferase domain containing 1
chr21_+_25688388 0.90 ENSDART00000125709
bicaudal-D-related protein 2
chr21_+_25625026 0.89 ENSDART00000134678
ovo-like zinc finger 1b
chr21_-_13149453 0.88 ENSDART00000172578
si:dkey-228b2.6
chr10_+_39084354 0.85 ENSDART00000158245
si:ch73-1a9.3
chr16_+_23961276 0.84 ENSDART00000192754
apolipoprotein Eb
chr1_-_46706639 0.81 ENSDART00000074519
karyopherin alpha 3 (importin alpha 4)
chr3_-_29977495 0.80 ENSDART00000077111
hydroxysteroid (17-beta) dehydrogenase 14
chr8_-_3312384 0.79 ENSDART00000035965
fucosyltransferase 9b
chr4_-_49069087 0.78 ENSDART00000150622
si:ch211-234c11.3
chr4_+_42078825 0.72 ENSDART00000164496
zinc finger protein 1060
chr1_-_53685090 0.72 ENSDART00000162751
exportin 1 (CRM1 homolog, yeast) a
chr5_+_30741730 0.71 ENSDART00000098246
ENSDART00000186992
ENSDART00000182533
finTRIM family, member 83
chr16_+_29509133 0.69 ENSDART00000112116
cathepsin S, ortholog2, tandem duplicate 1
chr10_-_7988396 0.67 ENSDART00000141445
ENSDART00000024282
EWS RNA-binding protein 1a
chr4_-_50434519 0.66 ENSDART00000150372
zinc finger protein 1061
chr25_-_34670413 0.65 ENSDART00000073440
DnaJ heat shock protein family (Hsp40) member A4
chr21_-_37973081 0.65 ENSDART00000136569
ripply transcriptional repressor 1
chr8_-_32805214 0.64 ENSDART00000131597
zgc:194839
chr14_-_31087830 0.64 ENSDART00000002250
heparan sulfate 6-O-sulfotransferase 2
chr3_-_26204867 0.64 ENSDART00000103748
glycerophosphodiester phosphodiesterase domain containing 3a
chr15_-_5901514 0.63 ENSDART00000155252
si:ch73-281n10.2
chr21_-_32436679 0.62 ENSDART00000076974
glutamine-fructose-6-phosphate transaminase 2
chr20_+_10166297 0.61 ENSDART00000141877
potassium channel, subfamily K, member 10a
chr22_+_18349794 0.60 ENSDART00000186580
GATA zinc finger domain containing 2Ab
chr15_-_34892664 0.58 ENSDART00000153787
ENSDART00000099721
ring finger protein 183
chr21_-_37733571 0.58 ENSDART00000176214
membrane protein, palmitoylated 1
chr4_-_16124417 0.57 ENSDART00000128079
ENSDART00000077664
ATPase plasma membrane Ca2+ transporting 1a
chr21_-_37733287 0.54 ENSDART00000157826
membrane protein, palmitoylated 1
chr4_+_33191390 0.53 ENSDART00000150429
si:dkey-247i3.6
chr7_-_26436436 0.53 ENSDART00000019035
ENSDART00000123395
hairy-related 8a
chr23_+_7471072 0.52 ENSDART00000135551
si:ch211-200e2.1
chr14_+_17137023 0.51 ENSDART00000080712
solute carrier family 43, member 3b
chr22_+_27284462 0.51 ENSDART00000164660
si:ch73-103b2.1
chr7_-_40656148 0.51 ENSDART00000142315
nucleolar protein with MIF4G domain 1
chr20_-_25631256 0.51 ENSDART00000048164
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr20_-_39367895 0.51 ENSDART00000136476
ENSDART00000021788
ENSDART00000180784
PDZ binding kinase
chr1_-_49361905 0.50 ENSDART00000144349
ENSDART00000184496
si:dkeyp-80c12.8
chr17_-_33416020 0.50 ENSDART00000140149
coiled-coil domain containing 28A
chr8_+_53051701 0.50 ENSDART00000131514
NAD kinase a
chr5_+_15203421 0.49 ENSDART00000040826
T-box 1
chr11_+_44579865 0.49 ENSDART00000173425
nidogen 1b
chr15_+_22014029 0.48 ENSDART00000079504
ankyrin repeat and kinase domain containing 1
chr25_+_30196039 0.48 ENSDART00000005299
hydroxysteroid (17-beta) dehydrogenase 12a
chr3_+_1150348 0.47 ENSDART00000148524
nucleolar protein 12
chr4_-_64141714 0.47 ENSDART00000128628

chr8_-_13541514 0.47 ENSDART00000063834
zgc:86586
chr4_+_18963822 0.46 ENSDART00000066975
ENSDART00000066973
IMP (inosine 5'-monophosphate) dehydrogenase 1b
chr3_-_53092509 0.46 ENSDART00000062081
lysophosphatidic acid receptor 2a
chr4_-_77979432 0.46 ENSDART00000049170
zgc:85975
chr6_+_41452979 0.46 ENSDART00000007353
WD repeat domain 82
chr4_-_35989745 0.46 ENSDART00000162568
zinc finger protein 1125
chr4_+_43074375 0.45 ENSDART00000150732
zinc finger protein 1137
chr4_+_6032640 0.45 ENSDART00000157487
transcription factor EC
chr7_+_57088920 0.45 ENSDART00000024076
secretory carrier membrane protein 2, like
chr12_+_38878830 0.45 ENSDART00000156926
si:ch211-39f2.3
chr25_-_17368231 0.44 ENSDART00000189291
cytochrome P450, family 2, subfamily X, polypeptide 6
chr10_+_36662640 0.44 ENSDART00000063359
uncoupling protein 2
chr15_-_34668485 0.44 ENSDART00000186605
BCL2 associated athanogene 6
chr7_-_56606752 0.44 ENSDART00000138714
sulfotransferase family 5A, member 1
chr6_+_58915889 0.44 ENSDART00000083628
DNA-damage-inducible transcript 3
chr14_+_9421510 0.43 ENSDART00000123652
high mobility group nucleosome binding domain 6
chr7_+_57089354 0.42 ENSDART00000140702
secretory carrier membrane protein 2, like
chr13_-_36535128 0.42 ENSDART00000043312
serine/arginine-rich splicing factor 5a
chr12_+_30233977 0.42 ENSDART00000188135
actin filament associated protein 1-like 2
chr11_+_7580079 0.42 ENSDART00000091550
ENSDART00000193223
ENSDART00000193386
adhesion G protein-coupled receptor L2a
chr3_-_7524363 0.41 ENSDART00000162970
zinc finger protein 1001
chr3_+_32425202 0.41 ENSDART00000156464
proline rich 12b
chr24_-_9979342 0.41 ENSDART00000138576
ENSDART00000191206
zgc:171977
chr16_-_27224246 0.40 ENSDART00000103257
asparagine-linked glycosylation 2 (alpha-1,3-mannosyltransferase)
chr13_-_24260609 0.40 ENSDART00000138747
URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
chr23_+_18779043 0.40 ENSDART00000158267
epithelial membrane protein 3b
chr2_-_25143373 0.40 ENSDART00000160108
neutral cholesterol ester hydrolase 1a
chr19_-_17304866 0.39 ENSDART00000160433
ENSDART00000190798
ENSDART00000171284
splicing factor 3a, subunit 3
chr5_-_28041715 0.39 ENSDART00000078660
zgc:113436
chr12_+_46634736 0.39 ENSDART00000008009
tripartite motif containing 16
chr4_-_67712607 0.38 ENSDART00000162955
zinc finger protein 1091
chr12_+_30234209 0.38 ENSDART00000102081
actin filament associated protein 1-like 2
chr16_+_27224369 0.38 ENSDART00000136980
Sec61 translocon beta subunit
chr3_-_1388936 0.38 ENSDART00000171278
DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
chr8_-_52715911 0.38 ENSDART00000168241
tubulin, beta 2b
chr3_+_6469754 0.37 ENSDART00000185809
nucleoporin 85
chr4_-_42015883 0.36 ENSDART00000163399
zinc finger protein 1145
chr11_-_308838 0.36 ENSDART00000112538
POC1 centriolar protein A
chr7_+_48806420 0.36 ENSDART00000083431
carnitine palmitoyltransferase 1Aa (liver)
chr4_+_13452437 0.35 ENSDART00000145069
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr4_-_58846245 0.35 ENSDART00000170777
si:dkey-28i19.1
chr16_+_51180938 0.35 ENSDART00000169022
high mobility group nucleosomal binding domain 2
chr8_-_13029297 0.35 ENSDART00000144305
DENN/MADD domain containing 2Da
chr3_-_38783951 0.34 ENSDART00000155518
zinc finger protein 281a
chr12_+_27024676 0.34 ENSDART00000153104
male-specific lethal 1 homolog b (Drosophila)
chr7_+_19835569 0.34 ENSDART00000149812
ovo-like zinc finger 1a
chr9_-_45602978 0.33 ENSDART00000139019
ENSDART00000085763
anterior gradient 1
chr14_-_31862657 0.33 ENSDART00000172870
ENSDART00000007927
ENSDART00000134748
ENSDART00000128730
RNA binding motif protein, X-linked
chr4_+_13452907 0.33 ENSDART00000186116
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr7_+_22792895 0.33 ENSDART00000184407
RNA binding motif protein 4.3
chr14_+_33329420 0.32 ENSDART00000171090
ENSDART00000164062
sosondowah ankyrin repeat domain family d
chr6_+_54248705 0.32 ENSDART00000162469
protein kinase C and casein kinase substrate in neurons 1b
chr14_+_52481288 0.32 ENSDART00000169164
ENSDART00000159297
transcription elongation regulator 1a (CA150)
chr13_+_13033837 0.32 ENSDART00000079558
leucine zipper-EF-hand containing transmembrane protein 1
chr15_+_25024685 0.32 ENSDART00000188889

chr5_+_26204561 0.32 ENSDART00000137178
MARVEL domain containing 2b
chr21_-_2565825 0.32 ENSDART00000169633
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein b
chr4_-_193762 0.31 ENSDART00000169667
protein tyrosine phosphatase, receptor type, O
chr5_+_19712011 0.31 ENSDART00000131924
family with sequence similarity 222, member A
chr4_-_22519516 0.31 ENSDART00000130409
ENSDART00000186258
ENSDART00000002851
ENSDART00000123801
lysine (K)-specific demethylase 7Aa
chr1_-_51474974 0.30 ENSDART00000152719
sprouty-related, EVH1 domain containing 2a
chr1_-_55183088 0.30 ENSDART00000100619
zgc:158803
chr5_-_54712159 0.30 ENSDART00000149207
cyclin B1
chr12_+_27156943 0.30 ENSDART00000153030
ENSDART00000001737
src kinase associated phosphoprotein 1
chr4_+_38937575 0.29 ENSDART00000150385
zinc finger protein 997
chr14_-_42997145 0.29 ENSDART00000172801
protocadherin 10b
chr13_-_12006007 0.29 ENSDART00000111438
meningioma expressed antigen 5 (hyaluronidase)
chr24_+_5935377 0.29 ENSDART00000191989
ENSDART00000185932
ENSDART00000131768
abl-interactor 1a
chr6_-_56111829 0.29 ENSDART00000154397
glucosaminyl (N-acetyl) transferase family member 7
chr6_-_35401282 0.28 ENSDART00000127612
regulator of G protein signaling 5a
chr11_+_6116503 0.28 ENSDART00000176170
nuclear receptor subfamily 2, group F, member 6b
chr25_-_13728111 0.28 ENSDART00000169865
lecithin-cholesterol acyltransferase
chr6_+_72040 0.28 ENSDART00000122957
crystallin, gamma M4
chr2_+_327081 0.28 ENSDART00000155595
zgc:174263
chr5_-_36592307 0.27 ENSDART00000126927
ENSDART00000051196
TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr23_-_9492055 0.27 ENSDART00000139688
suppressor of glucose, autophagy associated 1
chr10_+_44692272 0.27 ENSDART00000157458
ubiquitin C
chr21_-_36396334 0.27 ENSDART00000183627
mitochondrial ribosomal protein L22
chr2_-_30611389 0.27 ENSDART00000142500
catenin (cadherin-associated protein), delta 2b
chr21_+_36396864 0.27 ENSDART00000137309
gem (nuclear organelle) associated protein 5
chr16_+_27224068 0.26 ENSDART00000059013
Sec61 translocon beta subunit
chr6_+_3864040 0.26 ENSDART00000013743
golgi reassembly stacking protein 2
chr19_+_7154500 0.25 ENSDART00000035967
ENSDART00000160894
bromodomain containing 2a
chr16_-_27224000 0.25 ENSDART00000126347
asparagine-linked glycosylation 2 (alpha-1,3-mannosyltransferase)
chr15_-_4596623 0.25 ENSDART00000132227
eukaryotic translation initiation factor 4h
chr12_+_48841182 0.25 ENSDART00000109315
ENSDART00000185609
ENSDART00000187217
discs, large homolog 5b (Drosophila), tandem duplicate 1
chr18_-_7448047 0.24 ENSDART00000193213
ENSDART00000131940
ENSDART00000186944
ENSDART00000052803
si:dkey-30c15.10
chr3_-_40162843 0.24 ENSDART00000129664
ENSDART00000025285
developmentally regulated GTP binding protein 2
chr5_+_58665648 0.24 ENSDART00000167481
zgc:194948
chr4_-_26035770 0.24 ENSDART00000124514
ubiquitin specific peptidase 44
chr7_+_73670137 0.24 ENSDART00000050357
bloodthirsty-related gene family, member 12
chr22_+_18319230 0.24 ENSDART00000184747
ENSDART00000184649
GATA zinc finger domain containing 2Ab
chr23_-_9492266 0.23 ENSDART00000091852
suppressor of glucose, autophagy associated 1
chr8_+_36554816 0.23 ENSDART00000126687
splicing factor 3a, subunit 1
chr17_-_33415740 0.23 ENSDART00000135218
coiled-coil domain containing 28A
chr8_-_36554675 0.23 ENSDART00000132804
ENSDART00000078746
coiled-coil domain containing 157
chr20_-_22193190 0.23 ENSDART00000047624
transmembrane protein 165
chr23_-_21446985 0.23 ENSDART00000044080
hairy-related 12
chr11_-_36350876 0.23 ENSDART00000146495
ENSDART00000020655
proteasome subunit alpha 5
chr22_-_38459316 0.23 ENSDART00000149683
ENSDART00000098461
protein tyrosine kinase 7a
chr14_+_6535426 0.23 ENSDART00000055961
tRNA-histidine guanylyltransferase 1-like
chr9_+_21260314 0.23 ENSDART00000145943
spindle and kinetochore associated complex subunit 3
chr11_-_309420 0.22 ENSDART00000173185
POC1 centriolar protein A
chr8_+_22327251 0.22 ENSDART00000075129
leucine rich repeat containing 47
chr22_+_18319666 0.22 ENSDART00000033103
GATA zinc finger domain containing 2Ab
chr12_-_21681509 0.22 ENSDART00000112726
essential meiotic structure-specific endonuclease 1
chr15_-_21014270 0.21 ENSDART00000154019
si:ch211-212c13.10
chr7_-_59256806 0.21 ENSDART00000167955
meiosis 1 associated protein
chr12_-_4475890 0.21 ENSDART00000092492
si:ch211-173d10.1
chr21_-_2310355 0.21 ENSDART00000183326
si:ch211-241b2.1
chr5_-_67750907 0.21 ENSDART00000172097
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
chr8_-_29822527 0.21 ENSDART00000167487
solute carrier family 20 (phosphate transporter), member 2
chr21_+_30007566 0.21 ENSDART00000149124
ENSDART00000150071
tetratricopeptide repeat domain 1
chr20_-_14012859 0.20 ENSDART00000152429
si:ch211-22i13.2
chr5_+_50953240 0.20 ENSDART00000148501
ENSDART00000149892
ENSDART00000190312
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein a
chr3_-_23575007 0.20 ENSDART00000155282
ENSDART00000087726
insulin-like growth factor 2 mRNA binding protein 1
chr18_+_5172848 0.19 ENSDART00000190642

chr2_-_58075414 0.19 ENSDART00000161920
nectin cell adhesion molecule 4
chr14_+_28438947 0.19 ENSDART00000006489
acyl-CoA synthetase long chain family member 4a
chr18_+_33725576 0.19 ENSDART00000146816
si:dkey-145c18.5
chr1_-_11104805 0.19 ENSDART00000147648
kinetochore scaffold 1
chr2_+_47906240 0.19 ENSDART00000122206
finTRIM family, member 23
chr6_+_4387150 0.19 ENSDART00000181283
RNA binding motif protein 26
chr10_-_36793412 0.19 ENSDART00000185966
dehydrogenase/reductase (SDR family) member 13a, tandem duplicate 2
chr11_-_36350421 0.19 ENSDART00000141477
proteasome subunit alpha 5
chr11_+_3246059 0.19 ENSDART00000161529
timeless circadian clock
chr7_-_54430505 0.19 ENSDART00000167905
anoctamin 1, calcium activated chloride channel
chr21_-_13668358 0.19 ENSDART00000180323
patatin-like phospholipase domain containing 7a
chr5_+_20319519 0.19 ENSDART00000004217
coronin, actin binding protein, 1Ca
chr12_-_10476448 0.19 ENSDART00000106172
Rac family small GTPase 1a
chr10_-_6587066 0.19 ENSDART00000171833
chromodomain helicase DNA binding protein 1
chr6_-_27108844 0.18 ENSDART00000073883
deoxythymidylate kinase (thymidylate kinase)
chr15_+_12429206 0.18 ENSDART00000168997
transmembrane protease, serine 4a
chr6_+_52927651 0.18 ENSDART00000141094
si:dkeyp-3f10.11
chr17_+_23255365 0.18 ENSDART00000180277

chr10_-_1523253 0.18 ENSDART00000179510
ENSDART00000176548
ENSDART00000180368
ENSDART00000185270
WD repeat domain 70
chr9_-_41088279 0.18 ENSDART00000000564
asparagine synthetase domain containing 1
chr8_-_20914829 0.18 ENSDART00000025356
HAUS augmin-like complex, subunit 5
chr22_-_21176269 0.18 ENSDART00000112839
required for excision 1-B domain containing
chr3_+_41585298 0.18 ENSDART00000182370
caspase recruitment domain family, member 11
chr12_+_48841419 0.18 ENSDART00000125331
discs, large homolog 5b (Drosophila), tandem duplicate 1
chr16_+_33938227 0.18 ENSDART00000166254
GPN-loop GTPase 2

Network of associatons between targets according to the STRING database.

First level regulatory network of tfcp2+tfcp2l1+ubp1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0034382 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
0.3 0.8 GO:0032757 interleukin-8 production(GO:0032637) regulation of interleukin-8 production(GO:0032677) positive regulation of interleukin-8 production(GO:0032757)
0.2 0.9 GO:0055107 Golgi to secretory granule transport(GO:0055107)
0.2 1.1 GO:0061194 rhombomere 5 development(GO:0021571) rhombomere 6 development(GO:0021572) tongue development(GO:0043586) tongue morphogenesis(GO:0043587) taste bud development(GO:0061193) taste bud morphogenesis(GO:0061194) taste bud formation(GO:0061195)
0.2 0.7 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.2 0.5 GO:0003156 regulation of organ formation(GO:0003156)
0.2 0.5 GO:0034214 protein hexamerization(GO:0034214)
0.2 0.5 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.1 0.6 GO:0034505 tooth mineralization(GO:0034505)
0.1 1.0 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.1 0.4 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.1 2.7 GO:0001757 somite specification(GO:0001757)
0.1 0.4 GO:0015074 DNA integration(GO:0015074)
0.1 0.5 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.1 0.6 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.1 0.7 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.9 GO:0019372 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 0.2 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.1 1.5 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 0.5 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 0.8 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.4 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 0.3 GO:0048025 negative regulation of RNA splicing(GO:0033119) negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.1 0.2 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.1 0.2 GO:0051352 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.1 0.5 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 0.4 GO:1990845 adaptive thermogenesis(GO:1990845)
0.1 0.5 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.1 0.3 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 0.3 GO:0070285 pigment cell development(GO:0070285)
0.0 0.2 GO:0071459 protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.0 0.5 GO:0006177 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.0 0.2 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.0 0.7 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0 0.1 GO:0003249 cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250) endocardial cell development(GO:0060958) cell proliferation involved in heart valve development(GO:2000793)
0.0 0.2 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.0 0.2 GO:0000741 karyogamy(GO:0000741) pronuclear fusion(GO:0007344)
0.0 0.4 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.6 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.2 GO:0043111 replication fork arrest(GO:0043111)
0.0 0.3 GO:0021794 thalamus development(GO:0021794)
0.0 0.4 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.0 0.2 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0 0.2 GO:0031106 septin ring organization(GO:0031106) septin cytoskeleton organization(GO:0032185)
0.0 0.3 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.3 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.3 GO:0090660 cerebrospinal fluid circulation(GO:0090660)
0.0 0.2 GO:1900744 regulation of p38MAPK cascade(GO:1900744)
0.0 0.3 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:1990403 embryonic brain development(GO:1990403)
0.0 0.6 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.2 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.2 GO:0016081 synaptic vesicle docking(GO:0016081) presynaptic dense core granule exocytosis(GO:0099525)
0.0 0.2 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.6 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.1 GO:1901533 negative regulation of hematopoietic progenitor cell differentiation(GO:1901533)
0.0 0.1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.3 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.3 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.2 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 0.2 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.1 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.1 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.2 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0000423 macromitophagy(GO:0000423)
0.0 0.1 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.0 0.5 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.2 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732) negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.1 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.1 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.1 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.0 0.7 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.0 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.0 0.3 GO:0051923 sulfation(GO:0051923)
0.0 0.2 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.9 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.0 GO:0070987 error-free translesion synthesis(GO:0070987)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.1 0.6 GO:0005784 Sec61 translocon complex(GO:0005784)
0.1 0.3 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.1 0.4 GO:0071818 BAT3 complex(GO:0071818)
0.1 1.1 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 0.3 GO:0070062 extracellular exosome(GO:0070062)
0.1 0.2 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.0 0.9 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.3 GO:0072487 MSL complex(GO:0072487)
0.0 0.4 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.2 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.2 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.2 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.5 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.1 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.1 GO:1902636 kinociliary basal body(GO:1902636)
0.0 0.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.3 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.2 GO:0042555 MCM complex(GO:0042555)
0.0 0.5 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.1 GO:0030990 intraciliary transport particle(GO:0030990)
0.0 0.2 GO:0005686 U2 snRNP(GO:0005686)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.2 1.5 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.2 0.7 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.1 0.8 GO:0042169 SH2 domain binding(GO:0042169)
0.1 1.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.9 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.1 0.5 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.1 0.6 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.1 0.5 GO:0051139 calcium:proton antiporter activity(GO:0015369) metal ion:proton antiporter activity(GO:0051139)
0.1 1.0 GO:0004586 ornithine decarboxylase activity(GO:0004586)
0.1 0.4 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 0.6 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 2.3 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.4 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 0.5 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.7 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.2 GO:0009041 uridylate kinase activity(GO:0009041)
0.1 0.5 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.1 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.1 0.2 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.1 0.4 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.8 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.2 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.0 0.2 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.0 0.2 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.2 GO:0033592 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.0 0.2 GO:0070568 guanylyltransferase activity(GO:0070568)
0.0 0.2 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.5 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 1.2 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.2 GO:0004984 olfactory receptor activity(GO:0004984) odorant binding(GO:0005549)
0.0 0.3 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.6 GO:0022841 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 0.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.3 GO:0031386 protein tag(GO:0031386)
0.0 0.2 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.2 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.3 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.4 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.2 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.5 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.8 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.3 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.1 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 2.6 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.1 GO:0030116 glial cell-derived neurotrophic factor receptor binding(GO:0030116)
0.0 0.1 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.1 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.1 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.1 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.4 PID ATR PATHWAY ATR signaling pathway
0.0 0.7 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.5 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.4 PID ATF2 PATHWAY ATF-2 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 1.0 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.4 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.7 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.3 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.4 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 1.0 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 0.6 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.8 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.1 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.2 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants