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PRJNA195909:zebrafish embryo and larva development

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Results for tbx20

Z-value: 0.27

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Transcription factors associated with tbx20

Gene Symbol Gene ID Gene Info
ENSDARG00000005150 T-box transcription factor 20

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
tbx20dr11_v1_chr16_-_42523744_425237440.294.6e-01Click!

Activity profile of tbx20 motif

Sorted Z-values of tbx20 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_32228538 0.51 ENSDART00000077471
myosin heavy chain 4
chr1_-_59360114 0.50 ENSDART00000160445

chr21_+_30351256 0.49 ENSDART00000078341
forkhead box I3a
chr3_-_5964557 0.42 ENSDART00000184738

chr25_+_36152215 0.35 ENSDART00000036147
iroquois homeobox 5b
chr21_-_2273244 0.35 ENSDART00000171417
si:ch73-299h12.3
chr9_+_23900703 0.32 ENSDART00000127859
tripartite motif containing 63b
chr4_+_47257854 0.32 ENSDART00000173868
crestin
chr12_-_43664682 0.31 ENSDART00000159423
forkhead box i1
chr2_+_43469241 0.30 ENSDART00000142078
ENSDART00000098265
neuropilin 1b
chr6_+_9130989 0.29 ENSDART00000162588
regucalcin
chr5_+_12515402 0.29 ENSDART00000103278
zgc:171242
chr15_-_31516558 0.29 ENSDART00000156427
ENSDART00000156072
ENSDART00000156047
high mobility group box 1b
chr13_-_31812394 0.28 ENSDART00000124445
SERTA domain containing 4
chr11_+_24729346 0.28 ENSDART00000087740
zgc:153953
chr1_-_26027327 0.26 ENSDART00000171292
ENSDART00000170878
si:ch211-145b13.6
chr3_-_33417826 0.25 ENSDART00000084284
ABI family, member 3a
chr19_+_26718074 0.24 ENSDART00000134455
zgc:100906
chr7_-_69853453 0.22 ENSDART00000049928
myozenin 2a
chr7_+_39389273 0.21 ENSDART00000191298
troponin I type 2b (skeletal, fast), tandem duplicate 2
chr24_+_13869092 0.21 ENSDART00000176492
EYA transcriptional coactivator and phosphatase 1
chr8_-_52859301 0.20 ENSDART00000162004
nuclear receptor subfamily 5, group A, member 1a
chr5_-_44843738 0.19 ENSDART00000003926
fructose-1,6-bisphosphatase 1a
chr22_-_34872533 0.18 ENSDART00000167176
slit homolog 1b (Drosophila)
chr12_+_15290800 0.18 ENSDART00000145656
mediator complex subunit 1
chr1_-_462165 0.18 ENSDART00000152799
si:ch73-244f7.3
chr25_+_37130450 0.17 ENSDART00000183358
si:ch1073-174d20.1
chr17_+_26965351 0.17 ENSDART00000114215
ENSDART00000147192
grainyhead-like transcription factor 3
chr20_+_826459 0.16 ENSDART00000104740
5'-nucleotidase, ecto (CD73)
chr2_-_31301929 0.16 ENSDART00000191992
ENSDART00000190723
adenylate cyclase activating polypeptide 1b
chr14_+_20911310 0.15 ENSDART00000160318
lysozyme g-like 2
chr7_+_38249858 0.15 ENSDART00000150158
si:dkey-78a14.4
chr8_+_68864 0.14 ENSDART00000164574
proline rich 16
chr12_+_763051 0.14 ENSDART00000152579
ATP-binding cassette, sub-family C (CFTR/MRP), member 3
chr7_+_756942 0.12 ENSDART00000152224
zgc:63470
chr3_-_8285123 0.11 ENSDART00000158699
ENSDART00000138588
tripartite motif containing 35-9
chr11_+_44622472 0.11 ENSDART00000159068
ENSDART00000166323
ENSDART00000187753
RNA binding motif protein 34
chr25_-_7686201 0.10 ENSDART00000157267
ENSDART00000155094
si:ch211-286c4.6
chr13_+_18276187 0.10 ENSDART00000141009
tet methylcytosine dioxygenase 1
chr4_+_32156734 0.10 ENSDART00000163904

chr24_+_41940299 0.09 ENSDART00000022349
erythrocyte membrane protein band 4.1-like 3a
chr3_+_25857008 0.09 ENSDART00000154899
ENSDART00000193762
zgc:171844
chr24_+_42948 0.09 ENSDART00000122785
thioredoxin related transmembrane protein 3b
chr21_+_40232910 0.09 ENSDART00000075915
odorant receptor, family F, subfamily 115, member 11
chr23_+_21380079 0.09 ENSDART00000089379
intermediate filament family orphan 2a
chr11_-_44622478 0.07 ENSDART00000171837
tubulin folding cofactor E
chr3_+_52475058 0.07 ENSDART00000035867
si:ch211-241f5.3
chr23_-_45049044 0.07 ENSDART00000067630
SH3 domain containing GRB2 like 2, endophilin A1
chr2_+_15776156 0.07 ENSDART00000190795
vav 3 guanine nucleotide exchange factor b
chr11_-_12104917 0.06 ENSDART00000136108
mitochondrial ribosomal protein L45
chr5_+_9382301 0.06 ENSDART00000124017
UDP glucuronosyltransferase 2 family, polypeptide A7
chr10_+_11355841 0.05 ENSDART00000193067
ENSDART00000064215
COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)
chr16_-_563732 0.05 ENSDART00000183394
iroquois homeobox 2a
chr11_-_44622240 0.05 ENSDART00000172258
ENSDART00000173340
tubulin folding cofactor E
chr8_-_11112058 0.05 ENSDART00000042755
adenosine monophosphate deaminase 1 (isoform M)
chr5_-_49012569 0.05 ENSDART00000184690
si:dkey-172m14.2
chr4_+_35138928 0.05 ENSDART00000167934
ENSDART00000192116
ENSDART00000183689
si:dkey-279j5.1
chr1_-_46326156 0.05 ENSDART00000040284
ATPase phospholipid transporting 11A
chr3_-_5555500 0.05 ENSDART00000176133
ENSDART00000057464
tripartite motif containing 35-31
chr3_+_17314997 0.05 ENSDART00000139763
signal transducer and activator of transcription 5a
chr17_-_15600455 0.05 ENSDART00000110272
ENSDART00000156911
si:ch211-266g18.9
chr12_+_3848109 0.04 ENSDART00000144067
ENSDART00000192042
calcium binding protein 5a
chr8_+_36416285 0.04 ENSDART00000158400
si:busm1-194e12.8
chr15_+_43799258 0.04 ENSDART00000122238
tyrosinase
chr4_+_59320243 0.04 ENSDART00000150611
zinc finger protein 1084
chr4_+_38103421 0.04 ENSDART00000164164
zinc finger protein 1016
chr20_-_31808779 0.04 ENSDART00000133788
syntaxin binding protein 5a (tomosyn)
chr21_+_5494561 0.03 ENSDART00000169728
lymphocyte antigen 6 family member M3
chr24_+_26742226 0.03 ENSDART00000079721
growth hormone secretagogue receptor b
chr16_-_7379328 0.03 ENSDART00000060447
mediator of RNA polymerase II transcription, subunit 18 homolog (yeast)
chr20_-_116999 0.03 ENSDART00000149581
yippee-like 5
chr4_-_75812937 0.03 ENSDART00000125096
si:ch211-203c5.3
chr12_+_49100365 0.03 ENSDART00000171905

chr25_-_35107791 0.02 ENSDART00000192819
zgc:165555
chr4_+_59234719 0.02 ENSDART00000170724
ENSDART00000192143
ENSDART00000109914
zinc finger protein 1086
chr18_-_51015718 0.02 ENSDART00000190698

chr25_+_37285737 0.02 ENSDART00000126879
transmembrane p24 trafficking protein 6
chr5_-_36549024 0.02 ENSDART00000097671
zgc:158432
chr17_+_33375469 0.02 ENSDART00000032827
zgc:162964
chr19_+_177455 0.01 ENSDART00000111580
transmembrane protein 65
chr25_+_19170500 0.01 ENSDART00000182572

chr12_+_19362547 0.01 ENSDART00000180148
G1 to S phase transition 1
chr12_-_48127985 0.01 ENSDART00000193805
neuropeptide FF receptor 1
chr7_+_6879534 0.01 ENSDART00000157731
zgc:175248
chr16_+_12660477 0.01 ENSDART00000016834
activation-induced cytidine deaminase
chr8_+_30747940 0.00 ENSDART00000098975
purinergic receptor P2X, ligand-gated ion channel, 4b
chr17_+_33496067 0.00 ENSDART00000184724
parathyroid hormone 2
chr2_+_15776408 0.00 ENSDART00000176628
vav 3 guanine nucleotide exchange factor b

Network of associatons between targets according to the STRING database.

First level regulatory network of tbx20

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0009957 epidermal cell fate specification(GO:0009957)
0.1 0.3 GO:0042364 L-ascorbic acid metabolic process(GO:0019852) water-soluble vitamin biosynthetic process(GO:0042364)
0.1 0.2 GO:0005985 sucrose metabolic process(GO:0005985) sucrose biosynthetic process(GO:0005986) disaccharide biosynthetic process(GO:0046351)
0.1 0.2 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.1 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.3 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.0 0.2 GO:0009169 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.3 GO:0018120 peptidyl-arginine ADP-ribosylation(GO:0018120)
0.0 0.2 GO:2001239 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.1 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.1 GO:0032616 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.0 0.2 GO:0030325 adrenal gland development(GO:0030325)
0.0 0.0 GO:0042416 dopamine biosynthetic process from tyrosine(GO:0006585) dopamine biosynthetic process(GO:0042416)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.2 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.1 GO:1904861 excitatory synapse assembly(GO:1904861)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 0.2 GO:0016521 pituitary adenylate cyclase activating polypeptide activity(GO:0016521)
0.0 0.1 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.3 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.3 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.2 GO:0031433 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.0 0.3 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.0 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 0.1 GO:0016972 thiol oxidase activity(GO:0016972)
0.0 0.1 GO:0043014 alpha-tubulin binding(GO:0043014)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts