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PRJNA195909:zebrafish embryo and larva development

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Results for tal1

Z-value: 1.45

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Transcription factors associated with tal1

Gene Symbol Gene ID Gene Info
ENSDARG00000019930 T-cell acute lymphocytic leukemia 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
tal1dr11_v1_chr22_+_16535575_165355750.068.7e-01Click!

Activity profile of tal1 motif

Sorted Z-values of tal1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_44715224 3.41 ENSDART00000184630
si:dkey-56m19.5
chr17_-_10073926 1.73 ENSDART00000166081
ENSDART00000161574
zgc:109986
chr2_-_16565690 1.67 ENSDART00000022549
ATPase Na+/K+ transporting subunit beta 3a
chr11_+_30296332 1.66 ENSDART00000192843
UDP glucuronosyltransferase 1 family, polypeptide B7
chr19_-_24555935 1.64 ENSDART00000132660
ENSDART00000162801
polymerase (RNA) III (DNA directed) polypeptide G like a
chr14_-_3381303 1.57 ENSDART00000171601
im:7150988
chr19_-_24555623 1.57 ENSDART00000176022
polymerase (RNA) III (DNA directed) polypeptide G like a
chr7_+_24049776 1.50 ENSDART00000166559
embryonal Fyn-associated substrate
chr3_-_29977495 1.49 ENSDART00000077111
hydroxysteroid (17-beta) dehydrogenase 14
chr8_-_1051438 1.47 ENSDART00000067093
ENSDART00000170737
SET and MYND domain containing 1b
chr21_+_53504 1.44 ENSDART00000170452
dimethylglycine dehydrogenase
chr16_+_54875530 1.42 ENSDART00000149795
nuclear receptor subfamily 0, group B, member 2a
chr14_+_9421510 1.39 ENSDART00000123652
high mobility group nucleosome binding domain 6
chr7_+_26029672 1.38 ENSDART00000101126
arachidonate 12-lipoxygenase
chr1_-_52494122 1.36 ENSDART00000131407
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr15_-_26636826 1.35 ENSDART00000087632
solute carrier family 47 (multidrug and toxin extrusion), member 4
chr20_+_2281933 1.32 ENSDART00000137579
si:ch73-18b11.2
chr7_+_56577906 1.26 ENSDART00000184023
haptoglobin
chr15_-_14064302 1.19 ENSDART00000156384

chr10_+_4987766 1.16 ENSDART00000121959
si:ch73-234b20.5
chr3_-_6767440 1.14 ENSDART00000156174
microtubule associated serine/threonine kinase 1b
chr7_+_56577522 1.12 ENSDART00000149130
ENSDART00000149624
haptoglobin
chr23_+_578218 1.08 ENSDART00000055134
opioid growth factor receptor
chr4_+_8638622 1.01 ENSDART00000186829
wingless-type MMTV integration site family, member 5b
chr2_-_36350082 0.99 ENSDART00000193104

chr18_-_46010 0.95 ENSDART00000052641
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr10_-_36808348 0.94 ENSDART00000099320
dehydrogenase/reductase (SDR family) member 13a, tandem duplicate 1
chr7_-_6470431 0.92 ENSDART00000081359
zgc:110425
chr11_+_25259058 0.92 ENSDART00000154109
tumor protein p53 inducible nuclear protein 2
chr19_-_48010490 0.86 ENSDART00000159938
zgc:158376
chr1_-_8980665 0.86 ENSDART00000148182
si:ch73-191k20.3
chr4_-_48636872 0.82 ENSDART00000168605
zinc finger protein 1063
chr13_+_40770628 0.80 ENSDART00000085846
NK1 transcription factor related 2-like,a
chr17_-_681142 0.77 ENSDART00000165583
heme-binding protein soul3
chr3_+_54581987 0.76 ENSDART00000018071
eukaryotic translation initiation factor 3, subunit G
chr6_-_51573975 0.73 ENSDART00000073865
retinoblastoma-like 1 (p107)
chr4_+_41311345 0.73 ENSDART00000151905
si:dkey-16p19.8
chr13_-_9525527 0.72 ENSDART00000190618

chr23_+_26079467 0.71 ENSDART00000129617
ATPase H+ transporting accessory protein 1b
chr5_+_42467867 0.69 ENSDART00000172028
Pim proto-oncogene, serine/threonine kinase, related 58
chr15_-_47857687 0.69 ENSDART00000098982
ENSDART00000151594
H3 histone, family 3B.1
chr19_+_1964005 0.69 ENSDART00000172049
SH3-domain binding protein 5a (BTK-associated)
chr1_-_59141715 0.69 ENSDART00000164941
ENSDART00000138870
si:ch1073-110a20.1
chr25_+_1732838 0.68 ENSDART00000159555
ENSDART00000168161
fibulin 1
chr4_-_52165969 0.68 ENSDART00000171130
si:dkeyp-44b5.4
chr16_+_42772678 0.67 ENSDART00000155575
si:ch211-135n15.2
chr7_-_27033080 0.66 ENSDART00000173516
nucleobindin 2a
chr16_-_41990421 0.65 ENSDART00000055921
PYD and CARD domain containing
chr24_-_26310854 0.65 ENSDART00000080113
apolipoprotein Db
chr15_+_47525073 0.65 ENSDART00000067583
SID1 transmembrane family, member 2
chr14_+_17125428 0.63 ENSDART00000161489
solute carrier family 43, member 3b
chr17_+_53156530 0.61 ENSDART00000126277
ENSDART00000156774
diphthamine biosynthesis 6
chr24_-_9300160 0.60 ENSDART00000152378
TGFB-induced factor homeobox 1
chr24_-_26399623 0.60 ENSDART00000112317
zgc:194621
chr1_+_54871725 0.59 ENSDART00000193654
si:ch211-196h16.5
chr3_-_1232384 0.58 ENSDART00000053892
si:ch1073-314i13.4
chr2_-_55903520 0.58 ENSDART00000128828
complexin 4c
chr23_-_36934944 0.57 ENSDART00000109976
ENSDART00000162179
ArfGAP with coiled-coil, ankyrin repeat and PH domains 3a
chr4_+_5249494 0.57 ENSDART00000150391
si:ch211-214j24.14
chr8_+_46327350 0.57 ENSDART00000145618
si:dkey-75a21.2
chr1_+_27868294 0.57 ENSDART00000165332
DnaJ (Hsp40) homolog, subfamily B, member 14
chr4_-_58964138 0.57 ENSDART00000150259
si:ch211-64i20.3
chr25_-_36369057 0.57 ENSDART00000064400
si:ch211-113a14.24
chr22_-_16494406 0.57 ENSDART00000062727
syntaxin 6
chr4_-_76488581 0.57 ENSDART00000174291
finTRIM family, member 51
chr2_+_49864219 0.56 ENSDART00000187744
ribosomal protein L37
chr22_-_26353916 0.55 ENSDART00000077958
calpain 2, (m/II) large subunit b
chr1_+_52560549 0.54 ENSDART00000167514
ATP-binding cassette, sub-family A (ABC1), member 1A
chr4_-_65747476 0.54 ENSDART00000142421
si:dkey-28k24.2
chr21_-_217589 0.53 ENSDART00000185017

chr4_+_38170708 0.52 ENSDART00000168900
zinc finger protein 1071
chr9_-_23747264 0.52 ENSDART00000141461
ENSDART00000010311
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10
chr3_-_36115339 0.51 ENSDART00000187406
ENSDART00000123505
ENSDART00000151775
RAB11 family interacting protein 4 (class II) a
chr16_+_46807214 0.51 ENSDART00000185524

chr22_-_28373698 0.51 ENSDART00000157592
si:ch211-213c4.5
chr5_+_338154 0.50 ENSDART00000191743
ring finger protein 170
chr24_+_17269849 0.49 ENSDART00000017605
sperm associated antigen 6
chr17_-_39786222 0.49 ENSDART00000154515
Pim proto-oncogene, serine/threonine kinase, related 62
chr5_-_65000312 0.49 ENSDART00000192893
zgc:110283
chr7_+_42935126 0.49 ENSDART00000157747

chr15_-_40267485 0.48 ENSDART00000152253
potassium inwardly-rectifying channel, subfamily J, member 13
chr4_-_48578324 0.47 ENSDART00000122707
zinc finger protein 980
chr4_-_74466703 0.46 ENSDART00000174032
ENSDART00000189417

chr25_+_258883 0.46 ENSDART00000155256
zgc:92481
chr1_+_49686408 0.46 ENSDART00000140824
si:ch211-149l1.2
chr25_+_35212919 0.45 ENSDART00000180127
anoctamin 5a
chr14_-_36862745 0.45 ENSDART00000109293
ring finger protein 130
chr13_+_22316746 0.45 ENSDART00000188968
ubiquitin specific peptidase 54a
chr16_-_41503925 0.44 ENSDART00000029492
CKLF-like MARVEL transmembrane domain containing 7
chr1_+_52563298 0.44 ENSDART00000142465
ATP-binding cassette, sub-family A (ABC1), member 1A
chr25_+_15933411 0.43 ENSDART00000191581
PTPRF interacting protein, binding protein 2b (liprin beta 2)
chr4_+_37952218 0.43 ENSDART00000186865
si:dkeyp-82b4.2
chr2_-_59157790 0.43 ENSDART00000192303
ENSDART00000159362
finTRIM family, member 32
chr5_+_37785152 0.43 ENSDART00000053511
ENSDART00000189812
myosin Ic, paralog a
chr4_+_34126849 0.43 ENSDART00000162442
si:ch211-223g7.6
chr17_+_53311618 0.42 ENSDART00000166517
ankyrin repeat and SOCS box containing 2b
chr4_+_64562090 0.42 ENSDART00000188810
si:ch211-223a21.3
chr12_-_656540 0.42 ENSDART00000172651
sulfotransferase family 2, cytosolic sulfotransferase 2
chr3_-_61592417 0.40 ENSDART00000155082
neuronal pentraxin 2a
chr3_+_4266289 0.40 ENSDART00000101636
si:dkey-73p2.1
chr10_-_8294965 0.40 ENSDART00000167380
phospholipid phosphatase 1a
chr10_-_43928937 0.40 ENSDART00000168014
ENSDART00000086220
multiple C2 domains, transmembrane 1b
chr22_-_10541372 0.39 ENSDART00000179708
si:dkey-42i9.4
chr3_+_3545825 0.39 ENSDART00000109060

chr14_+_31865099 0.39 ENSDART00000189124
transmembrane 9 superfamily protein member 5
chr4_-_43911462 0.39 ENSDART00000189056
ENSDART00000162441
ENSDART00000171367
zinc finger protein 1104
chr3_+_30500968 0.38 ENSDART00000103447
si:dkey-13n23.3
chr3_-_58226583 0.38 ENSDART00000187429
im:6904045
chr2_-_30200206 0.38 ENSDART00000130142
ubiquitin-conjugating enzyme E2W (putative)
chr17_+_10074360 0.38 ENSDART00000166649
signal recognition particle 54
chr4_+_31293362 0.38 ENSDART00000169781
si:dkey-57l19.1
chr2_-_59265521 0.38 ENSDART00000146341
ENSDART00000097799
finTRIM family, member 33
chr3_+_58833306 0.37 ENSDART00000113223
immunoglobulin light 1 constant 3
chr17_+_53439606 0.37 ENSDART00000154946
si:zfos-1714f5.3
chr25_-_35153985 0.37 ENSDART00000154851
zgc:153405
chr4_-_32456788 0.37 ENSDART00000151862
si:dkey-16p6.1
chr1_+_292545 0.37 ENSDART00000148261
centromere protein E
chr3_-_1388936 0.37 ENSDART00000171278
DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
chr23_-_36910656 0.37 ENSDART00000139563
ArfGAP with coiled-coil, ankyrin repeat and PH domains 3a
chr4_-_67589158 0.37 ENSDART00000184361

chr6_+_9241121 0.36 ENSDART00000064989
Pim proto-oncogene, serine/threonine kinase, related 70
chr25_-_36044583 0.36 ENSDART00000073432
retinoblastoma-like 2 (p130)
chr8_+_39570615 0.36 ENSDART00000142557
leucine zipper, putative tumor suppressor 1
chr21_-_45073764 0.36 ENSDART00000181390
ENSDART00000063714
Rap guanine nucleotide exchange factor (GEF) 6
chr4_-_1497384 0.36 ENSDART00000093236
zmp:0000000711
chr16_+_19014886 0.35 ENSDART00000079298
si:ch211-254p10.2
chr5_-_67762434 0.35 ENSDART00000167301
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
chr3_+_5504990 0.35 ENSDART00000143626
si:ch73-264i18.2
chr24_+_35827766 0.35 ENSDART00000144700
si:dkeyp-7a3.1
chr10_+_26896142 0.35 ENSDART00000188225
EH domain binding protein 1-like 1b
chr5_+_65946222 0.34 ENSDART00000190969
ENSDART00000161578
myomaker, myoblast fusion factor
chr7_+_5964296 0.34 ENSDART00000173380
si:dkey-23a13.17
chr3_-_10970502 0.34 ENSDART00000127500

chr2_+_13694450 0.34 ENSDART00000077259
ENSDART00000189485
EBNA1 binding protein 2
chr17_-_24838927 0.34 ENSDART00000123259

chr16_-_19568795 0.33 ENSDART00000185141
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr1_+_55452892 0.33 ENSDART00000122508

chr4_-_76129431 0.32 ENSDART00000162809
si:ch211-106j21.2
chr21_-_45382112 0.32 ENSDART00000151029
ENSDART00000151335
ENSDART00000151687
ENSDART00000075438
CDKN2A interacting protein N-terminal like
chr25_-_18470695 0.32 ENSDART00000034377
carboxypeptidase A5
chr21_-_23331619 0.32 ENSDART00000007806
zinc finger and BTB domain containing 16a
chr8_+_22491947 0.32 ENSDART00000125805
si:ch211-261n11.8
chr4_-_2052687 0.32 ENSDART00000138291
ENSDART00000150844
cleavage and polyadenylation specific factor 6
chr2_+_20793982 0.32 ENSDART00000014785
proteoglycan 4a
chr11_-_26040594 0.32 ENSDART00000144115
kazrin, periplakin interacting protein b
chr1_-_59232267 0.32 ENSDART00000169658
ENSDART00000163257
A kinase (PRKA) anchor protein 8-like
chr11_+_6136220 0.31 ENSDART00000082223
Tax1 (human T-cell leukemia virus type I) binding protein 3
chr7_-_6346859 0.31 ENSDART00000172913
si:ch73-368j24.11
chr1_+_52130213 0.31 ENSDART00000018817
ring finger protein 11a
chr11_-_8782871 0.31 ENSDART00000158546
si:ch211-51h4.2
chr20_-_31075972 0.31 ENSDART00000122927
si:ch211-198b3.4
chr25_-_3549321 0.31 ENSDART00000181214
ENSDART00000160600
haloacid dehalogenase like hydrolase domain containing 5
chr14_-_25928899 0.30 ENSDART00000143518
GTPase activating protein (SH3 domain) binding protein 1
chr10_+_40633990 0.30 ENSDART00000190489
ENSDART00000139474
si:ch211-238p8.31
chr10_-_5020378 0.30 ENSDART00000191857
heterogeneous nuclear ribonucleoprotein D
chr2_-_59345920 0.30 ENSDART00000134662
finTRIM family, member 37
chr10_-_8295294 0.30 ENSDART00000075412
ENSDART00000163803
phospholipid phosphatase 1a
chr23_-_16682186 0.30 ENSDART00000020810
syndecan binding protein (syntenin) 2
chr24_-_6029314 0.30 ENSDART00000136155
finTRIM family, member 60
chr4_-_38033800 0.29 ENSDART00000159662
si:dkeyp-82b4.4
chr18_+_48802154 0.29 ENSDART00000191403
bone morphogenetic protein 16
chr7_+_33132074 0.29 ENSDART00000073554
zgc:153219
chr1_-_206208 0.29 ENSDART00000060968
ADP-ribosylhydrolase like 1
chr19_-_43639331 0.29 ENSDART00000138009
ENSDART00000086138
family with sequence similarity 83, member Hb
chr24_-_36337395 0.29 ENSDART00000154402
si:ch211-40k21.9
chr5_-_26181863 0.28 ENSDART00000098500
coiled-coil domain containing 125
chr19_+_43978814 0.28 ENSDART00000102314
naked cuticle homolog 3
chr9_-_1499721 0.28 ENSDART00000062940
si:ch211-222f23.6
chr7_-_50917255 0.28 ENSDART00000022918
ankyrin repeat domain 46b
chr4_+_50401133 0.28 ENSDART00000150644
si:dkey-156k2.7
chr21_-_5007109 0.28 ENSDART00000187042
ENSDART00000097796
ENSDART00000146766
ring finger protein 165a
chr18_-_20560007 0.28 ENSDART00000141367
ENSDART00000090186
si:ch211-238n5.4
chr2_-_42492201 0.27 ENSDART00000180762
ENSDART00000009093
extended synaptotagmin-like protein 2a
chr2_-_59247811 0.27 ENSDART00000141384
finTRIM family, member 32
chr14_-_9281232 0.27 ENSDART00000054693
ankyrin repeat and SOCS box-containing 12b
chr20_-_26929685 0.27 ENSDART00000132556
finTRIM family, member 79
chr24_-_6038025 0.27 ENSDART00000077819
ENSDART00000139216
finTRIM family, member 61
chr17_+_132555 0.27 ENSDART00000158159
zgc:77287
chr12_+_18533198 0.27 ENSDART00000189729
meiosis specific with OB domains
chr25_-_173165 0.26 ENSDART00000193594

chr24_+_38155830 0.26 ENSDART00000152019
si:ch211-234p6.5
chr12_-_45238759 0.26 ENSDART00000154859
tripartite motif containing 65
chr25_+_37290206 0.26 ENSDART00000086474
si:dkey-234i14.12
chr3_+_3598555 0.26 ENSDART00000191152

chr19_+_31404686 0.26 ENSDART00000078459
phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2
chr3_-_62380146 0.25 ENSDART00000155853
G protein-coupled receptor, class C, group 5, member Ba
chr21_+_22840246 0.25 ENSDART00000151621
baculoviral IAP repeat containing 2
chr18_-_8398972 0.25 ENSDART00000136512
si:ch211-220f12.4
chr7_+_6317866 0.25 ENSDART00000173397
si:ch211-220f21.3
chr25_+_3318192 0.25 ENSDART00000146154
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3b
chr18_-_5248365 0.25 ENSDART00000082506
ENSDART00000082504
ENSDART00000097960
myelin expression factor 2
chr3_-_5413018 0.25 ENSDART00000063138
vitelline membrane outer layer 1 homolog a
chr4_+_61171310 0.25 ENSDART00000141738
si:dkey-9p20.18
chr14_-_22108718 0.25 ENSDART00000054410
mediator complex subunit 19a
chr1_+_2260407 0.24 ENSDART00000058876
karyopherin (importin) beta 3
chr1_-_513762 0.24 ENSDART00000148162
ENSDART00000144606
tRNA methyltransferase 10C, mitochondrial RNase P subunit
chr7_+_25053331 0.24 ENSDART00000173998
si:dkey-23i12.7
chr3_-_3939785 0.24 ENSDART00000049593
un-named sa1506
chr14_-_32258759 0.24 ENSDART00000052949
fibroblast growth factor 13a
chr20_+_27020201 0.24 ENSDART00000126919
ENSDART00000016014
chromogranin A

Network of associatons between targets according to the STRING database.

First level regulatory network of tal1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0006601 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
0.3 1.5 GO:0090527 actin filament reorganization(GO:0090527)
0.2 1.0 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.2 1.0 GO:0008591 regulation of Wnt signaling pathway, calcium modulating pathway(GO:0008591) positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.2 1.2 GO:0070254 mucus secretion(GO:0070254)
0.1 0.7 GO:1901207 regulation of heart looping(GO:1901207)
0.1 1.5 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.1 0.5 GO:0051876 pigment granule dispersal(GO:0051876)
0.1 2.1 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.3 GO:0046689 response to mercury ion(GO:0046689) detoxification of mercury ion(GO:0050787)
0.1 0.3 GO:0032239 regulation of nucleobase-containing compound transport(GO:0032239) positive regulation of nucleobase-containing compound transport(GO:0032241) positive regulation of nucleocytoplasmic transport(GO:0046824) regulation of RNA export from nucleus(GO:0046831) positive regulation of RNA export from nucleus(GO:0046833) messenger ribonucleoprotein complex assembly(GO:1990120)
0.1 0.3 GO:2000008 regulation of protein localization to cell surface(GO:2000008) negative regulation of protein localization to cell surface(GO:2000009)
0.1 3.2 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 0.6 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 1.2 GO:0019372 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 1.8 GO:0036376 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.1 0.3 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 0.2 GO:0042755 eating behavior(GO:0042755)
0.1 0.3 GO:0014743 regulation of muscle hypertrophy(GO:0014743)
0.1 0.2 GO:0002792 negative regulation of peptide secretion(GO:0002792) negative regulation of peptide hormone secretion(GO:0090278)
0.1 0.2 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.1 0.6 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 1.5 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.1 0.7 GO:0032096 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.1 0.3 GO:0060547 negative regulation of necroptotic process(GO:0060546) negative regulation of necrotic cell death(GO:0060547)
0.1 0.2 GO:2000815 regulation of mRNA stability involved in response to stress(GO:0010610) regulation of mRNA stability involved in response to oxidative stress(GO:2000815)
0.1 0.2 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.1 0.7 GO:0061099 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732) negative regulation of protein tyrosine kinase activity(GO:0061099)
0.1 0.2 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.4 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.7 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.4 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.8 GO:2000134 negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.2 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.1 GO:0046443 FAD biosynthetic process(GO:0006747) FAD metabolic process(GO:0046443) flavin adenine dinucleotide metabolic process(GO:0072387) flavin adenine dinucleotide biosynthetic process(GO:0072388)
0.0 0.2 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.0 0.2 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.0 0.2 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.0 0.2 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.6 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.5 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.2 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.1 GO:1903573 negative regulation of response to endoplasmic reticulum stress(GO:1903573)
0.0 0.8 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.8 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.2 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.0 0.3 GO:2000406 positive regulation of lymphocyte migration(GO:2000403) positive regulation of T cell migration(GO:2000406)
0.0 0.1 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.0 0.3 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.0 0.1 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.0 0.3 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.1 GO:0051031 tRNA transport(GO:0051031)
0.0 0.1 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.7 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.0 0.7 GO:0007568 aging(GO:0007568)
0.0 1.0 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.2 GO:1904825 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.0 0.1 GO:0042421 octopamine biosynthetic process(GO:0006589) dopamine catabolic process(GO:0042420) norepinephrine biosynthetic process(GO:0042421) octopamine metabolic process(GO:0046333)
0.0 0.1 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.4 GO:0071218 response to misfolded protein(GO:0051788) cellular response to misfolded protein(GO:0071218)
0.0 0.5 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.2 GO:0043490 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.0 0.2 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.3 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.2 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.0 0.4 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.4 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.1 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0 0.4 GO:0051923 sulfation(GO:0051923)
0.0 0.2 GO:0051967 negative regulation of cytosolic calcium ion concentration(GO:0051481) negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.2 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.2 GO:0006265 DNA topological change(GO:0006265)
0.0 0.1 GO:0060855 venous endothelial cell migration involved in lymph vessel development(GO:0060855)
0.0 0.2 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 1.2 GO:0071466 cellular response to xenobiotic stimulus(GO:0071466)
0.0 0.2 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.5 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.0 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) Schwann cell migration(GO:0036135) cardiac neuron differentiation(GO:0060945) cardiac neuron development(GO:0060959)
0.0 0.4 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.0 0.3 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.2 0.7 GO:0061702 inflammasome complex(GO:0061702)
0.1 3.0 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.7 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.1 0.4 GO:0060171 stereocilium membrane(GO:0060171)
0.1 0.3 GO:0042382 paraspeckles(GO:0042382)
0.1 1.5 GO:0031430 M band(GO:0031430)
0.1 0.4 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.3 GO:0070062 extracellular exosome(GO:0070062)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.6 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.2 GO:0070390 transcription export complex 2(GO:0070390)
0.0 0.8 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.0 0.2 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.3 GO:0045095 keratin filament(GO:0045095)
0.0 0.6 GO:0043195 terminal bouton(GO:0043195)
0.0 2.6 GO:0000786 nucleosome(GO:0000786)
0.0 0.2 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.9 GO:0016605 PML body(GO:0016605)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.4 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.2 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.2 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.9 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.5 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.3 GO:0034399 nuclear periphery(GO:0034399)
0.0 1.2 GO:0030141 secretory granule(GO:0030141)
0.0 0.5 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 2.8 GO:0000785 chromatin(GO:0000785)
0.0 0.5 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.6 GO:0005925 cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.4 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.2 0.7 GO:0000810 diacylglycerol diphosphate phosphatase activity(GO:0000810)
0.2 1.0 GO:0090556 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.2 3.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 1.1 GO:0004985 opioid receptor activity(GO:0004985)
0.1 1.4 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.3 GO:0045545 syndecan binding(GO:0045545)
0.1 0.4 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1 0.3 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.1 0.9 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 1.3 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.1 1.1 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 1.7 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.4 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 1.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 0.2 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.2 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.7 GO:0022884 macromolecule transmembrane transporter activity(GO:0022884)
0.0 0.7 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.2 GO:0031005 filamin binding(GO:0031005)
0.0 0.4 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.1 GO:0003919 FMN adenylyltransferase activity(GO:0003919)
0.0 0.2 GO:0046592 polyamine oxidase activity(GO:0046592)
0.0 0.3 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.1 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.0 0.1 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 1.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.1 GO:0071568 UFM1 transferase activity(GO:0071568)
0.0 0.9 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.0 0.2 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 1.1 GO:0005109 frizzled binding(GO:0005109)
0.0 0.4 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.7 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.0 0.2 GO:0032977 membrane insertase activity(GO:0032977)
0.0 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.5 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.3 GO:0043028 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0 0.1 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.0 0.7 GO:0003823 antigen binding(GO:0003823)
0.0 0.1 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.0 0.2 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.3 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.1 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 0.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.0 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.2 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 0.2 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 0.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.1 GO:0019863 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.2 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 1.4 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.5 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.1 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.1 GO:0033781 cholesterol 24-hydroxylase activity(GO:0033781)
0.0 0.3 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.0 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.0 0.1 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.3 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.6 GO:0019843 rRNA binding(GO:0019843)
0.0 0.2 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.9 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.2 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 1.3 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.6 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.8 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.1 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.1 REACTOME PURINE SALVAGE Genes involved in Purine salvage