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PRJNA195909:zebrafish embryo and larva development
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Results for tal1
Z-value: 1.45
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Transcription factors associated with tal1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| tal1 | dr11_v1_chr22_+_16535575_16535575 | 0.06 | 8.7e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr7_+_44715224 Show fit | 3.41 |
ENSDART00000184630
|
si:dkey-56m19.5 |
|
| chr17_-_10073926 Show fit | 1.73 |
ENSDART00000166081
ENSDART00000161574 |
zgc:109986 |
|
| chr2_-_16565690 Show fit | 1.67 |
ENSDART00000022549
|
ATPase Na+/K+ transporting subunit beta 3a |
|
| chr11_+_30296332 Show fit | 1.66 |
ENSDART00000192843
|
UDP glucuronosyltransferase 1 family, polypeptide B7 |
|
| chr19_-_24555935 Show fit | 1.64 |
ENSDART00000132660
ENSDART00000162801 |
polymerase (RNA) III (DNA directed) polypeptide G like a |
|
| chr14_-_3381303 Show fit | 1.57 |
ENSDART00000171601
|
im:7150988 |
|
| chr19_-_24555623 Show fit | 1.57 |
ENSDART00000176022
|
polymerase (RNA) III (DNA directed) polypeptide G like a |
|
| chr7_+_24049776 Show fit | 1.50 |
ENSDART00000166559
|
embryonal Fyn-associated substrate |
|
| chr3_-_29977495 Show fit | 1.49 |
ENSDART00000077111
|
hydroxysteroid (17-beta) dehydrogenase 14 |
|
| chr8_-_1051438 Show fit | 1.47 |
ENSDART00000067093
ENSDART00000170737 |
SET and MYND domain containing 1b |
Network of associatons between targets according to the STRING database.
First level regulatory network of tal1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.2 | GO:0006383 | transcription from RNA polymerase III promoter(GO:0006383) |
| 0.1 | 2.1 | GO:0016584 | nucleosome positioning(GO:0016584) |
| 0.1 | 1.8 | GO:0036376 | cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436) |
| 0.3 | 1.5 | GO:0090527 | actin filament reorganization(GO:0090527) |
| 0.1 | 1.5 | GO:0030240 | skeletal muscle thin filament assembly(GO:0030240) |
| 0.1 | 1.5 | GO:0043433 | negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433) |
| 0.2 | 1.2 | GO:0070254 | mucus secretion(GO:0070254) |
| 0.1 | 1.2 | GO:0019372 | lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122) |
| 0.0 | 1.2 | GO:0071466 | cellular response to xenobiotic stimulus(GO:0071466) |
| 0.2 | 1.0 | GO:0010874 | regulation of cholesterol efflux(GO:0010874) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.0 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.0 | 2.8 | GO:0000785 | chromatin(GO:0000785) |
| 0.0 | 2.6 | GO:0000786 | nucleosome(GO:0000786) |
| 0.2 | 1.7 | GO:0090533 | sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533) |
| 0.0 | 1.6 | GO:0005925 | cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925) |
| 0.1 | 1.5 | GO:0031430 | M band(GO:0031430) |
| 0.0 | 1.2 | GO:0030141 | secretory granule(GO:0030141) |
| 0.0 | 0.9 | GO:0016605 | PML body(GO:0016605) |
| 0.0 | 0.9 | GO:0031305 | integral component of mitochondrial inner membrane(GO:0031305) |
| 0.0 | 0.8 | GO:0016282 | eukaryotic 43S preinitiation complex(GO:0016282) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 3.5 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.1 | 1.7 | GO:0001671 | ATPase activator activity(GO:0001671) |
| 0.0 | 1.7 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
| 0.4 | 1.4 | GO:0046997 | oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997) |
| 0.1 | 1.4 | GO:0004046 | aminoacylase activity(GO:0004046) |
| 0.1 | 1.4 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
| 0.0 | 1.4 | GO:0019905 | syntaxin binding(GO:0019905) |
| 0.1 | 1.3 | GO:0042910 | xenobiotic transporter activity(GO:0042910) |
| 0.1 | 1.1 | GO:0004985 | opioid receptor activity(GO:0004985) |
| 0.1 | 1.1 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.3 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.0 | 0.3 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.0 | 0.2 | PID INTEGRIN A9B1 PATHWAY | Alpha9 beta1 integrin signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.3 | REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
| 0.0 | 0.8 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.1 | 0.7 | REACTOME THE NLRP3 INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
| 0.0 | 0.6 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.0 | 0.4 | REACTOME G0 AND EARLY G1 | Genes involved in G0 and Early G1 |
| 0.0 | 0.4 | REACTOME N GLYCAN ANTENNAE ELONGATION | Genes involved in N-Glycan antennae elongation |
| 0.0 | 0.3 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.0 | 0.3 | REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT | Genes involved in ABC-family proteins mediated transport |
| 0.0 | 0.2 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.0 | 0.2 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |