Project
PRJNA195909:zebrafish embryo and larva development
Navigation
Downloads
Results for stat1a+stat2-1_stat1b
Z-value: 1.47
Motif logo
Transcription factors associated with stat1a+stat2-1_stat1b
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
| ENSDARG00000006266 | signal transducer and activator of transcription 1a | |
| ENSDARG00000031647 | signal transducer and activator of transcription 2 | |
| ENSDARG00000076182 | signal transducer and activator of transcription 1b |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| stat1b | dr11_v1_chr9_+_41224100_41224100 | -0.53 | 1.4e-01 | Click! |
| stat2 | dr11_v1_chr6_-_39158953_39158953 | -0.45 | 2.2e-01 | Click! |
| stat1a | dr11_v1_chr22_+_12798569_12798569 | 0.25 | 5.1e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr3_-_61205711 Show fit | 5.06 |
ENSDART00000055062
|
parvalbumin 1 |
|
| chr12_-_3133483 Show fit | 3.48 |
ENSDART00000015092
|
collagen, type I, alpha 1b |
|
| chr1_+_19535144 Show fit | 3.06 |
ENSDART00000103089
|
si:dkey-245p14.4 |
|
| chr21_-_27338639 Show fit | 2.55 |
ENSDART00000130632
|
hypoxia-inducible factor 1, alpha subunit, like 2 |
|
| chr7_+_48319916 Show fit | 2.53 |
ENSDART00000052122
|
cellular retinoic acid binding protein 1b |
|
| chr19_+_48176745 Show fit | 2.38 |
ENSDART00000164963
|
PR domain containing 1b, with ZNF domain |
|
| chr14_+_6159162 Show fit | 2.31 |
ENSDART00000128638
|
Bernardinelli-Seip congenital lipodystrophy 2, like |
|
| chr6_+_6491013 Show fit | 2.24 |
ENSDART00000140827
|
B cell CLL/lymphoma 11Ab |
|
| chr22_-_16180467 Show fit | 2.19 |
ENSDART00000171331
ENSDART00000185607 |
vascular cell adhesion molecule 1b |
|
| chr19_+_10846182 Show fit | 2.18 |
ENSDART00000168479
|
apolipoprotein A-IV a |
Network of associatons between targets according to the STRING database.
First level regulatory network of stat1a+stat2-1_stat1b
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 3.8 | GO:0034389 | lipid particle organization(GO:0034389) |
| 0.1 | 3.1 | GO:0006893 | Golgi to plasma membrane transport(GO:0006893) |
| 0.0 | 3.0 | GO:0030198 | extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062) |
| 0.5 | 2.5 | GO:0016115 | diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653) |
| 0.4 | 2.5 | GO:0021888 | hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888) |
| 0.1 | 2.5 | GO:0071456 | cellular response to hypoxia(GO:0071456) |
| 0.4 | 2.4 | GO:0033028 | neutrophil apoptotic process(GO:0001781) regulation of T-helper 1 type immune response(GO:0002825) positive regulation of T-helper 1 type immune response(GO:0002827) negative regulation of type 2 immune response(GO:0002829) inflammatory cell apoptotic process(GO:0006925) regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of phospholipase A2 activity(GO:0032429) interleukin-2 production(GO:0032623) regulation of interleukin-2 production(GO:0032663) positive regulation of interleukin-2 production(GO:0032743) myeloid cell apoptotic process(GO:0033028) regulation of neutrophil apoptotic process(GO:0033029) positive regulation of neutrophil apoptotic process(GO:0033031) regulation of myeloid cell apoptotic process(GO:0033032) positive regulation of myeloid cell apoptotic process(GO:0033034) T-helper 1 type immune response(GO:0042088) positive regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043372) T-helper 1 cell differentiation(GO:0045063) positive regulation of T-helper cell differentiation(GO:0045624) regulation of T-helper 1 cell differentiation(GO:0045625) positive regulation of T-helper 1 cell differentiation(GO:0045627) regulation of T-helper 2 cell differentiation(GO:0045628) negative regulation of T-helper 2 cell differentiation(GO:0045629) positive regulation of fatty acid biosynthetic process(GO:0045723) positive regulation of alpha-beta T cell differentiation(GO:0046638) neutrophil clearance(GO:0097350) negative regulation of phospholipase A2 activity(GO:1900138) positive regulation of CD4-positive, alpha-beta T cell activation(GO:2000516) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280) |
| 0.6 | 2.2 | GO:2000171 | negative regulation of dendrite development(GO:2000171) |
| 0.0 | 2.1 | GO:0008045 | motor neuron axon guidance(GO:0008045) |
| 0.0 | 2.0 | GO:0030514 | negative regulation of BMP signaling pathway(GO:0030514) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 7.3 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 4.4 | GO:0031012 | extracellular matrix(GO:0031012) |
| 0.0 | 4.0 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
| 0.1 | 3.1 | GO:0000145 | exocyst(GO:0000145) |
| 0.0 | 2.8 | GO:0008021 | synaptic vesicle(GO:0008021) |
| 0.2 | 2.4 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.0 | 2.4 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.0 | 2.0 | GO:0016324 | apical plasma membrane(GO:0016324) |
| 0.2 | 1.9 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.1 | 1.6 | GO:0031083 | BLOC-1 complex(GO:0031083) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 9.7 | GO:0005509 | calcium ion binding(GO:0005509) |
| 0.0 | 5.3 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.0 | 3.4 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.1 | 3.1 | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding(GO:0005546) |
| 0.0 | 2.6 | GO:0005179 | hormone activity(GO:0005179) |
| 0.3 | 2.5 | GO:0001972 | retinoic acid binding(GO:0001972) |
| 0.4 | 2.4 | GO:0019834 | phospholipase A2 inhibitor activity(GO:0019834) |
| 0.2 | 2.3 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
| 0.0 | 2.2 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.1 | 2.0 | GO:0001540 | beta-amyloid binding(GO:0001540) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.0 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.0 | 2.4 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.0 | 1.4 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.1 | 1.0 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.0 | 0.8 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.1 | 0.3 | ST PAC1 RECEPTOR PATHWAY | PAC1 Receptor Pathway |
| 0.0 | 0.2 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
| 0.0 | 0.1 | PID GMCSF PATHWAY | GMCSF-mediated signaling events |
| 0.0 | 0.1 | ST IL 13 PATHWAY | Interleukin 13 (IL-13) Pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.0 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.0 | 2.4 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
| 0.1 | 1.7 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.1 | 1.0 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.1 | 0.9 | REACTOME SYNTHESIS OF PC | Genes involved in Synthesis of PC |
| 0.0 | 0.9 | REACTOME COMPLEMENT CASCADE | Genes involved in Complement cascade |
| 0.0 | 0.6 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.0 | 0.6 | REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES | Genes involved in Cross-presentation of soluble exogenous antigens (endosomes) |
| 0.0 | 0.5 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 0.0 | 0.3 | REACTOME HDL MEDIATED LIPID TRANSPORT | Genes involved in HDL-mediated lipid transport |