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PRJNA195909:zebrafish embryo and larva development

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Results for spi2+spic

Z-value: 1.48

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Transcription factors associated with spi2+spic

Gene Symbol Gene ID Gene Info
ENSDARG00000012435 Spi-C transcription factor (Spi-1/PU.1 related)
ENSDARG00000087438 Spi-2 proto-oncogene

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
spi2dr11_v1_chr4_-_17803784_17803784-0.703.4e-02Click!
spicdr11_v1_chr4_-_17812131_17812131-0.333.8e-01Click!

Activity profile of spi2+spic motif

Sorted Z-values of spi2+spic motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_38287987 1.90 ENSDART00000185329
ENSDART00000061677
si:ch211-14a17.6
chr4_-_17263210 1.88 ENSDART00000147853
lymphoid-restricted membrane protein
chr9_+_8408054 1.80 ENSDART00000144373
zgc:153499
chr23_+_24989387 1.80 ENSDART00000172299
ENSDART00000145307
Rho GTPase activating protein 4a
chr13_+_31716820 1.61 ENSDART00000034745
protein kinase C, eta, a
chr12_-_33354409 1.57 ENSDART00000178515
solute carrier family 16 (monocarboxylate transporter), member 3
chr9_+_8407778 1.50 ENSDART00000102754
ENSDART00000178144
zgc:153499
chr12_+_13091842 1.41 ENSDART00000185477
ENSDART00000181435
ENSDART00000124799
si:ch211-103b1.2
chr15_+_34939906 1.32 ENSDART00000131182
si:ch73-95l15.3
chr9_-_35633827 1.32 ENSDART00000077745
zona pellucida glycoprotein 2, like 1
chr15_+_34940098 1.27 ENSDART00000099703
si:ch73-95l15.3
chr16_-_46393154 1.26 ENSDART00000132154
si:ch73-59c19.1
chr21_+_3244146 1.20 ENSDART00000127740
CBP80/20-dependent translation initiation factor
chr7_+_19600262 1.17 ENSDART00000007310
zgc:171731
chr8_-_49495584 1.16 ENSDART00000141691
opsin 7, group member d
chr16_+_20934353 1.13 ENSDART00000052660
src kinase associated phosphoprotein 2
chr14_-_16810401 1.13 ENSDART00000158396
ENSDART00000170758
T cell immune regulator 1, ATPase H+ transporting V0 subunit a3b
chr20_-_52928541 1.11 ENSDART00000162812
farnesyl-diphosphate farnesyltransferase 1
chr16_-_41488023 1.10 ENSDART00000169312
CKLF-like MARVEL transmembrane domain containing 6
chr22_-_11829436 1.07 ENSDART00000126784
protein tyrosine phosphatase, non-receptor type 4b
chr15_-_18209672 1.06 ENSDART00000141508
ENSDART00000136280
bloodthirsty-related gene family, member 16
chr13_-_18695289 1.03 ENSDART00000176809
sideroflexin 3
chr22_+_24623936 1.01 ENSDART00000160924
mucolipin 2
chr21_-_9769500 1.01 ENSDART00000170710
Rho GTPase activating protein 24
chr5_-_16475682 1.00 ENSDART00000090695
piwi-like RNA-mediated gene silencing 2
chr4_-_14191717 0.98 ENSDART00000147928
pseudouridylate synthase 7-like
chr15_-_34934784 0.97 ENSDART00000190848
DEAH (Asp-Glu-Ala-His) box polypeptide 16
chr8_+_8643901 0.97 ENSDART00000142076
ENSDART00000075624
ubiquitin specific peptidase 11
chr2_-_37462462 0.97 ENSDART00000145896
si:dkey-57k2.7
chr19_-_11431278 0.95 ENSDART00000109889
heat shock factor binding protein 1 like 1
chr18_+_45862414 0.94 ENSDART00000024615
arginyl aminopeptidase like 1
chr16_-_54919260 0.94 ENSDART00000156533
keratinocyte differentiation factor 1a
chr4_-_14191434 0.93 ENSDART00000142374
ENSDART00000136730
pseudouridylate synthase 7-like
chr2_-_51507540 0.93 ENSDART00000166605
ENSDART00000161093
polymeric immunoglobulin receptor-like 2.3
chr1_+_44053641 0.92 ENSDART00000124873
si:ch73-109d9.4
chr4_-_17353100 0.91 ENSDART00000134467
ENSDART00000189019
PARP1 binding protein
chr5_-_38248347 0.90 ENSDART00000084917
ENSDART00000139479
solute carrier family 12, member 9
chr17_-_10059557 0.90 ENSDART00000092209
ENSDART00000161243
bromodomain adjacent to zinc finger domain, 1A
chr13_+_11829072 0.89 ENSDART00000079356
ENSDART00000170160
suppressor of fused homolog (Drosophila)
chr24_+_39034090 0.89 ENSDART00000185763
calpain 15
chr14_-_24110251 0.89 ENSDART00000079226
cytoplasmic polyadenylation element binding protein 4a
chr15_+_34946779 0.88 ENSDART00000192661
ENSDART00000188800
ENSDART00000156515
si:ch73-95l15.5
zgc:55621
chr14_-_16807206 0.88 ENSDART00000157957
T cell immune regulator 1, ATPase H+ transporting V0 subunit a3b
chr20_-_49889111 0.87 ENSDART00000058858
kinesin family member 13Bb
chr21_+_76739 0.86 ENSDART00000174654
arylsulfatase B
chr20_+_2642855 0.86 ENSDART00000058775
zgc:101562
chr17_+_39790388 0.84 ENSDART00000149488
ubiquitin protein ligase E3 component n-recognin 1
chr16_-_41487589 0.84 ENSDART00000188115
CKLF-like MARVEL transmembrane domain containing 6
chr15_+_34934568 0.83 ENSDART00000165210
zgc:66024
chr10_+_5954787 0.82 ENSDART00000161887
ENSDART00000160345
ENSDART00000190046
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
chr21_+_18907102 0.82 ENSDART00000160185
ENSDART00000190175
ENSDART00000017937
ENSDART00000191546
ENSDART00000130519
ENSDART00000137143
sphingomyelin phosphodiesterase 4
chr7_+_39006837 0.82 ENSDART00000173735
diacylglycerol kinase, zeta a
chr1_+_26105141 0.82 ENSDART00000102379
ENSDART00000127154
topoisomerase I binding, arginine/serine-rich a
chr19_+_43669122 0.79 ENSDART00000139151
si:ch211-193k19.1
chr13_+_23104134 0.78 ENSDART00000110266
phosphoinositide-3-kinase adaptor protein 1
chr8_+_15277874 0.78 ENSDART00000146965
deoxynucleotidyltransferase, terminal, interacting protein 2
chr25_+_29688671 0.78 ENSDART00000073478
bromodomain containing 1b
chr3_-_34561624 0.78 ENSDART00000129313
septin 9a
chr11_+_44502410 0.78 ENSDART00000172998
endoplasmic reticulum oxidoreductase beta
chr7_+_24814866 0.77 ENSDART00000173581
si:ch211-226l4.6
chr23_-_28423222 0.77 ENSDART00000182058
complement component 1, q subcomponent-like 4
chr6_+_18418651 0.77 ENSDART00000171097
ENSDART00000167798
RAB11 family interacting protein 4 (class II) b
chr24_-_5691956 0.77 ENSDART00000189112
deleted in autism 1b
chr1_+_12394205 0.76 ENSDART00000138622
ENSDART00000136421
ENSDART00000139440
ENSDART00000184296
ENSDART00000008127
zgc:77739
chr23_-_14769523 0.76 ENSDART00000054909
glutathione synthetase
chr8_-_16725959 0.76 ENSDART00000183593
DEP domain containing 1a
chr16_-_10261652 0.75 ENSDART00000163599
si:rp71-15i12.1
chr16_+_38820486 0.75 ENSDART00000131866
thyrotropin-releasing hormone receptor a
chr24_-_24271629 0.74 ENSDART00000135060
ribosomal protein S6 kinase, polypeptide 3b
chr16_+_38820660 0.73 ENSDART00000182538
ENSDART00000189879
thyrotropin-releasing hormone receptor a
chr12_+_30368145 0.73 ENSDART00000153454
si:ch211-225b10.4
chr20_+_13141408 0.73 ENSDART00000034098
denticleless E3 ubiquitin protein ligase homolog (Drosophila)
chr1_+_15258641 0.72 ENSDART00000033018
phosphatidylinositol 4-kinase type 2 beta
chr18_+_14684115 0.71 ENSDART00000108469
spermatogenesis associated 2-like
chr11_+_2458264 0.71 ENSDART00000188341
TP53 regulating kinase
chr13_+_49727333 0.71 ENSDART00000168799
ENSDART00000037559
geranylgeranyl diphosphate synthase 1
chr19_+_11432330 0.71 ENSDART00000188065
PQ loop repeat containing 1
chr7_+_13684012 0.69 ENSDART00000056893
programmed cell death 7
chr6_-_15065376 0.69 ENSDART00000087797
transforming growth factor, beta receptor associated protein 1
chr23_-_28423048 0.69 ENSDART00000140448
complement component 1, q subcomponent-like 4
chr7_-_16597130 0.68 ENSDART00000144118
E2F transcription factor 8
chr21_+_34981263 0.68 ENSDART00000132711
RNA binding motif protein 11
chr1_+_12177195 0.68 ENSDART00000146842
ENSDART00000142081
STRA6-like
chr11_+_25157374 0.68 ENSDART00000019450
transient receptor potential cation channel, subfamily C, member 4 associated protein a
chr13_+_15580758 0.68 ENSDART00000087194
ENSDART00000013525
MAP/microtubule affinity-regulating kinase 3a
chr23_-_19684721 0.67 ENSDART00000184325
zgc:193598
chr7_-_16596938 0.67 ENSDART00000134548
E2F transcription factor 8
chr25_+_7532811 0.67 ENSDART00000161593
phosphatidylserine synthase 2
chr2_-_31800521 0.66 ENSDART00000112763
reticulophagy regulator 1
chr5_-_69482891 0.66 ENSDART00000109487

chr19_-_3821678 0.66 ENSDART00000169639
si:dkey-206d17.12
chr4_-_3353595 0.65 ENSDART00000009076
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr8_+_19977712 0.64 ENSDART00000134124
zinc finger protein 692
chr22_-_10539180 0.63 ENSDART00000131217
inositol 1,3,4,5,6-pentakisphosphate 2-kinase
chr3_+_46315016 0.63 ENSDART00000157199
MKL/myocardin-like 2b
chr13_+_7665890 0.63 ENSDART00000046792
golgi brefeldin A resistant guanine nucleotide exchange factor 1
chr8_-_13735572 0.63 ENSDART00000139642
si:dkey-258f14.7
chr10_+_29771256 0.63 ENSDART00000193195
hypoxia up-regulated 1
chr19_-_10915898 0.63 ENSDART00000163179
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, a
chr2_+_45696743 0.63 ENSDART00000114225
ENSDART00000169279

chr22_-_31020690 0.63 ENSDART00000130604
ssu-2 homolog, tandem duplicate 4
chr21_+_3941758 0.62 ENSDART00000181345
senataxin
chr6_+_13046720 0.61 ENSDART00000165896
caspase 8, apoptosis-related cysteine peptidase
chr25_+_28693451 0.61 ENSDART00000148366
CCR4-NOT transcription complex, subunit 2
chr11_+_25560632 0.61 ENSDART00000033914
methyl-CpG binding domain protein 1b
chr3_-_36364903 0.61 ENSDART00000028883
guanine nucleotide binding protein (G protein), alpha 13b
chr23_-_4225830 0.61 ENSDART00000170455
AAR2 splicing factor homolog (S. cerevisiae)
chr15_+_25489406 0.61 ENSDART00000162482
zgc:152863
chr2_-_32738535 0.60 ENSDART00000135293
nuclear receptor binding protein 2a
chr11_+_6882362 0.60 ENSDART00000144181
kelch-like family member 26
chr7_+_26545502 0.60 ENSDART00000140528
tyrosine kinase, non-receptor, 1
chr16_-_17586883 0.60 ENSDART00000017142
mannose-6-phosphate receptor (cation dependent)
chr17_-_28811747 0.60 ENSDART00000001444
G2/M-phase specific E3 ubiquitin protein ligase
chr8_-_20862443 0.60 ENSDART00000147267
si:ch211-133l5.8
chr1_-_34685329 0.60 ENSDART00000125944
ENSDART00000008277
progesterone immunomodulatory binding factor 1
chr17_+_45259259 0.60 ENSDART00000109532
ENSDART00000154890
glucosidase, alpha; neutral C
chr18_+_3243292 0.59 ENSDART00000166580
p21 protein (Cdc42/Rac)-activated kinase 1
chr5_+_23913585 0.59 ENSDART00000015401
excision repair cross-complementation group 6-like
chr3_-_55511569 0.59 ENSDART00000108995
testis expressed 2
chr6_-_40713183 0.59 ENSDART00000157113
ENSDART00000154810
ENSDART00000153702
si:ch211-157b11.12
chr8_-_32385989 0.59 ENSDART00000143716
ENSDART00000098850
lipase, endothelial
chr8_-_35960987 0.59 ENSDART00000160503
solute carrier family 15 (oligopeptide transporter), member 4
chr5_+_39099172 0.58 ENSDART00000006079
BMP2 inducible kinase
chr22_+_35275468 0.58 ENSDART00000189516
ENSDART00000181572
ENSDART00000165353
ENSDART00000185352
RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein
chr9_-_30385059 0.58 ENSDART00000060134
phosphatidylinositol glycan anchor biosynthesis, class A
chr8_-_30424182 0.58 ENSDART00000099021
dedicator of cytokinesis 8
chr12_+_47794089 0.58 ENSDART00000160726
polymerase (RNA) III (DNA directed) polypeptide A
chr7_+_24573721 0.58 ENSDART00000173938
ENSDART00000173681
si:dkeyp-75h12.7
chr12_-_9790485 0.58 ENSDART00000027321
PR domain containing 9
chr19_-_2085027 0.57 ENSDART00000063615
sorting nexin 13
chr16_+_33992418 0.57 ENSDART00000101885
ENSDART00000130540
zinc finger, DHHC-type containing 18a
chr5_-_22969424 0.57 ENSDART00000143869
ENSDART00000172549
si:dkey-237j10.2
chr9_-_32648725 0.57 ENSDART00000123374
DnaJ (Hsp40) homolog, subfamily B, member 11
chr7_-_50764714 0.57 ENSDART00000110283
IQ motif containing GTPase activating protein 1
chr2_+_35603637 0.57 ENSDART00000147278
polo-like kinase 3 (Drosophila)
chr3_-_16719244 0.57 ENSDART00000055859
polymerase (DNA directed), delta 1, catalytic subunit
chr19_-_31765615 0.56 ENSDART00000103636
si:dkeyp-120h9.1
chr9_-_704667 0.56 ENSDART00000147092
CASP8 and FADD-like apoptosis regulator b
chr5_-_57723929 0.56 ENSDART00000144237
grass carp reovirus (GCRV)-induced gene 2p
chr5_+_39099380 0.56 ENSDART00000166657
BMP2 inducible kinase
chr17_-_29213710 0.56 ENSDART00000076481
EH-domain containing 4
chr19_+_348729 0.56 ENSDART00000114284
MCL1, BCL2 family apoptosis regulator a
chr14_-_14687004 0.56 ENSDART00000169970
germ cell nuclear acidic peptidase
chr8_+_25959940 0.56 ENSDART00000143011
ENSDART00000140626
si:dkey-72l14.4
chr1_+_44554105 0.55 ENSDART00000149764
zinc finger, DHHC-type containing 5a
chr3_+_47131112 0.55 ENSDART00000165100
dynamin 2a
chr5_-_25733745 0.55 ENSDART00000051566
zgc:101016
chr14_+_41406321 0.55 ENSDART00000111480
BCL6 corepressor-like 1
chr9_+_13638329 0.55 ENSDART00000143432
amyotrophic lateral sclerosis 2a (juvenile)
chr5_-_24029228 0.55 ENSDART00000051546
ribosomal protein S6 kinase a, polypeptide 3a
chr2_+_7557912 0.55 ENSDART00000160053
receptor-interacting serine-threonine kinase 2
chr25_-_24240797 0.54 ENSDART00000132790
SPT2 chromatin protein domain containing 1
chr12_-_35944654 0.54 ENSDART00000162579
ENSDART00000164199
dynein, axonemal, intermediate chain 2a
chr23_+_7710447 0.54 ENSDART00000168199
kinesin family member 3B
chr22_+_35275206 0.54 ENSDART00000112234
RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein
chr17_-_25861787 0.54 ENSDART00000182503

chr7_+_26545911 0.54 ENSDART00000135313
tyrosine kinase, non-receptor, 1
chr21_-_7781555 0.54 ENSDART00000084380
ENSDART00000189131
angiogenic factor with G patch and FHA domains 1
chr20_+_27087539 0.54 ENSDART00000062094
transmembrane protein 251
chr11_-_36009924 0.54 ENSDART00000189959
ENSDART00000167472
ENSDART00000191211
ENSDART00000191662
ENSDART00000191780
ENSDART00000192622
ENSDART00000179911
inositol 1,4,5-trisphosphate receptor, type 1b
chr4_-_77252368 0.53 ENSDART00000111941
zgc:174310
chr6_+_49723289 0.53 ENSDART00000190452
syntaxin 16
chr20_-_18794789 0.53 ENSDART00000003834
cerebral cavernous malformation 2
chr19_+_31873308 0.53 ENSDART00000146560
ENSDART00000133045
si:dkeyp-34f6.4
chr9_+_70157 0.53 ENSDART00000140961
ENSDART00000192079
ENSDART00000157154
si:ch1073-55a19.2
chr9_-_27719998 0.53 ENSDART00000161068
ENSDART00000148195
ENSDART00000138386
general transcription factor IIE, polypeptide 1, alpha
chr3_+_46479913 0.53 ENSDART00000149755
tyrosine kinase 2
chr1_-_47114310 0.52 ENSDART00000144899
ENSDART00000053157
SET domain containing 4
chr7_+_57088920 0.52 ENSDART00000024076
secretory carrier membrane protein 2, like
chr7_+_32901658 0.52 ENSDART00000115420
anoctamin 9b
chr7_+_41887429 0.52 ENSDART00000115090
glutamic pyruvate transaminase (alanine aminotransferase) 2
chr7_+_25015151 0.52 ENSDART00000149966
ENSDART00000175583
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr9_+_24088062 0.52 ENSDART00000126198
leucine rich repeat (in FLII) interacting protein 1a
chr5_+_27137473 0.52 ENSDART00000181833
unc-5 netrin receptor Db
chr1_+_494297 0.52 ENSDART00000108579
ENSDART00000146732
basic leucine zipper nuclear factor 1
chr16_+_26439518 0.52 ENSDART00000041787
tripartite motif containing 35-28
chr15_-_25365319 0.52 ENSDART00000152651
clustered mitochondria (cluA/CLU1) homolog a
chr4_-_9867476 0.52 ENSDART00000091630
F-box protein, helicase, 18
chr19_+_42694211 0.51 ENSDART00000180153
cytoplasmic linker associated protein 2
chr6_+_29861288 0.51 ENSDART00000166782
discs, large homolog 1 (Drosophila)
chr3_-_40232615 0.51 ENSDART00000155969
flightless I actin binding protein
chr17_-_24587686 0.51 ENSDART00000143084
aftiphilin b
chr24_-_23839647 0.51 ENSDART00000125190
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
chr21_-_31207522 0.50 ENSDART00000191637
zgc:152891
chr12_-_17810543 0.50 ENSDART00000090484
tectonin beta-propeller repeat containing 1a
chr23_+_17980875 0.50 ENSDART00000163452
chitinase, acidic.6
chr19_+_43828104 0.50 ENSDART00000166031
elongin A
chr9_+_32649088 0.50 ENSDART00000136136
ENSDART00000172033
RAB, member of RAS oncogene family-like 3
chr7_-_40578733 0.50 ENSDART00000173926
ENSDART00000010035
DnaJ (Hsp40) homolog, subfamily B, member 6b
chr19_-_3741602 0.50 ENSDART00000170301
bloodthirsty-related gene family, member 22
chr23_-_36823932 0.50 ENSDART00000142305
homeodomain interacting protein kinase 1a
chr3_-_35865040 0.49 ENSDART00000102952
SUZ12 polycomb repressive complex 2a subunit
chr20_-_34711528 0.49 ENSDART00000061555
si:ch211-63o20.7
chr23_-_24955135 0.49 ENSDART00000136347
ENSDART00000144903
zinc finger and BTB domain containing 48
chr24_-_31092711 0.49 ENSDART00000168398
holocytochrome c synthase b
chr19_+_4066449 0.49 ENSDART00000162461
bloodthirsty-related gene family, member 26
chr5_-_41124241 0.49 ENSDART00000083561
myotubularin related protein 12
chr24_-_24796583 0.49 ENSDART00000144791
ENSDART00000146570
phosphodiesterase 7A
chr10_+_26990095 0.49 ENSDART00000064111
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed b
chr14_-_45558490 0.49 ENSDART00000165060
integrator complex subunit 5

Network of associatons between targets according to the STRING database.

First level regulatory network of spi2+spic

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0035046 pronuclear migration(GO:0035046)
0.4 1.1 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) negative regulation of lipid kinase activity(GO:0090219)
0.3 1.4 GO:0033301 cell cycle comprising mitosis without cytokinesis(GO:0033301)
0.3 1.0 GO:0001112 DNA-templated transcriptional open complex formation(GO:0001112) transcriptional open complex formation at RNA polymerase II promoter(GO:0001113) protein-DNA complex remodeling(GO:0001120)
0.3 1.0 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.2 0.9 GO:1904590 regulation of protein import into nucleus(GO:0042306) negative regulation of protein import into nucleus(GO:0042308) negative regulation of nucleocytoplasmic transport(GO:0046823) negative regulation of protein localization to nucleus(GO:1900181) regulation of protein import(GO:1904589) negative regulation of protein import(GO:1904590)
0.2 0.6 GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism(GO:0043903)
0.2 0.6 GO:0080182 histone H3-K4 trimethylation(GO:0080182) histone H3-K36 dimethylation(GO:0097676)
0.2 0.6 GO:0010658 negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.2 0.6 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.2 0.8 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.2 0.9 GO:0010481 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.2 1.1 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.2 0.5 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.2 1.0 GO:0003232 bulbus arteriosus development(GO:0003232)
0.2 0.7 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.2 0.8 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.2 1.0 GO:1900028 wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.2 0.7 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.2 0.7 GO:1902165 regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902165)
0.2 0.6 GO:0052746 inositol phosphorylation(GO:0052746)
0.2 0.5 GO:0031591 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.2 0.5 GO:0010526 regulation of transposition, RNA-mediated(GO:0010525) negative regulation of transposition, RNA-mediated(GO:0010526) transposition, RNA-mediated(GO:0032197) positive regulation of neuron apoptotic process(GO:0043525) positive regulation of neuron death(GO:1901216)
0.2 0.6 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.2 0.9 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 0.4 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 2.0 GO:0045851 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.1 0.4 GO:0042908 xenobiotic transport(GO:0042908)
0.1 0.6 GO:0048308 organelle inheritance(GO:0048308) Golgi inheritance(GO:0048313)
0.1 0.6 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.1 1.1 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
0.1 0.7 GO:0071938 vitamin A transport(GO:0071938) vitamin A import(GO:0071939)
0.1 0.8 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.9 GO:0002931 response to ischemia(GO:0002931)
0.1 0.5 GO:0050746 regulation of lipoprotein metabolic process(GO:0050746) regulation of protein lipidation(GO:1903059)
0.1 0.7 GO:0006013 mannose metabolic process(GO:0006013)
0.1 0.6 GO:0033238 regulation of cellular amino acid metabolic process(GO:0006521) regulation of cellular amine metabolic process(GO:0033238)
0.1 1.9 GO:0035803 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 0.3 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.1 0.3 GO:0090069 regulation of ribosome biogenesis(GO:0090069)
0.1 0.8 GO:0072425 signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in G2 DNA damage checkpoint(GO:0072425)
0.1 0.5 GO:1903573 negative regulation of response to endoplasmic reticulum stress(GO:1903573)
0.1 0.5 GO:0017003 protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063)
0.1 0.4 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.1 0.9 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.1 0.4 GO:0071265 L-methionine biosynthetic process from methylthioadenosine(GO:0019509) amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.1 0.6 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 0.9 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1 1.0 GO:0039023 pronephric duct morphogenesis(GO:0039023)
0.1 1.0 GO:0034605 cellular response to heat(GO:0034605)
0.1 0.5 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.1 0.6 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.1 1.4 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.1 1.0 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 0.9 GO:0006611 protein export from nucleus(GO:0006611)
0.1 0.7 GO:0061709 reticulophagy(GO:0061709)
0.1 0.8 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.3 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 0.4 GO:0009794 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.1 0.4 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.1 0.6 GO:0006857 oligopeptide transport(GO:0006857)
0.1 0.4 GO:1990108 protein linear deubiquitination(GO:1990108)
0.1 0.4 GO:0033119 negative regulation of RNA splicing(GO:0033119) negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.1 0.3 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 0.4 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.1 0.7 GO:0070525 tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.1 0.2 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.1 0.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.8 GO:0006032 chitin catabolic process(GO:0006032)
0.1 1.7 GO:0001522 pseudouridine synthesis(GO:0001522)
0.1 0.3 GO:0051660 establishment of centrosome localization(GO:0051660)
0.1 0.5 GO:0043584 nose development(GO:0043584)
0.1 0.2 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.1 0.3 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.1 0.5 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.2 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.1 0.4 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 0.3 GO:0070987 error-free translesion synthesis(GO:0070987)
0.1 0.9 GO:0002138 retinoic acid biosynthetic process(GO:0002138)
0.1 0.2 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1 0.6 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.1 0.4 GO:0098773 ventricular trabecula myocardium morphogenesis(GO:0003222) trabecula formation(GO:0060343) heart trabecula formation(GO:0060347) skin epidermis development(GO:0098773)
0.1 0.3 GO:1904867 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576) protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) protein localization to nucleoplasm(GO:1990173)
0.1 0.6 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 0.8 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.1 0.5 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.2 GO:1904182 regulation of pyruvate dehydrogenase activity(GO:1904182) positive regulation of pyruvate dehydrogenase activity(GO:1904184)
0.1 0.3 GO:0042264 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264) negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.1 0.3 GO:0035678 neuromast hair cell morphogenesis(GO:0035678)
0.1 0.8 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.1 0.2 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531)
0.1 0.3 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.9 GO:0043507 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.4 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 1.2 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.1 GO:0071869 response to monoamine(GO:0071867) response to catecholamine(GO:0071869) response to epinephrine(GO:0071871)
0.0 0.5 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.5 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.0 1.0 GO:0031297 replication fork processing(GO:0031297)
0.0 1.1 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.4 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.5 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.4 GO:2000273 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.0 1.1 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.5 GO:0035108 limb morphogenesis(GO:0035108)
0.0 0.2 GO:0010332 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.0 0.7 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.0 0.3 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.9 GO:1902807 negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.4 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.5 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.5 GO:0019372 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.2 GO:1905168 positive regulation of double-strand break repair via homologous recombination(GO:1905168)
0.0 0.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607) nuclear pore organization(GO:0006999)
0.0 1.2 GO:2001243 negative regulation of intrinsic apoptotic signaling pathway(GO:2001243)
0.0 0.8 GO:0007032 endosome organization(GO:0007032)
0.0 0.3 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.2 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.3 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.7 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.2 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 0.5 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.1 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 0.2 GO:0048855 adenohypophysis morphogenesis(GO:0048855)
0.0 0.5 GO:0045116 protein neddylation(GO:0045116)
0.0 0.7 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.0 0.8 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.1 GO:0030220 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.0 0.6 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.2 GO:0071423 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.0 0.6 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.4 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.4 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.5 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.1 GO:0055021 regulation of cardiac muscle tissue growth(GO:0055021) regulation of cardiac muscle cell proliferation(GO:0060043)
0.0 0.5 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.3 GO:0043550 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.4 GO:0010737 protein kinase A signaling(GO:0010737)
0.0 0.6 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.5 GO:0044818 mitotic G2/M transition checkpoint(GO:0044818)
0.0 0.3 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.3 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.7 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.0 0.4 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.6 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 1.2 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.5 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.3 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 0.5 GO:2000404 regulation of T cell migration(GO:2000404)
0.0 1.8 GO:0030336 negative regulation of cell migration(GO:0030336)
0.0 0.4 GO:0035675 neuromast hair cell development(GO:0035675)
0.0 0.7 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 1.0 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 0.2 GO:0043697 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.0 0.1 GO:0032370 positive regulation of lipid transport(GO:0032370)
0.0 0.8 GO:0006513 protein monoubiquitination(GO:0006513)
0.0 0.3 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.0 0.4 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.0 0.3 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.1 GO:2001106 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.3 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.5 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0 0.1 GO:0070291 N-acylethanolamine metabolic process(GO:0070291)
0.0 0.3 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.1 GO:0010039 response to iron ion(GO:0010039)
0.0 1.0 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.3 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.5 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.6 GO:0016082 synaptic vesicle priming(GO:0016082)
0.0 0.3 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.1 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 1.5 GO:0099518 vesicle cytoskeletal trafficking(GO:0099518)
0.0 0.3 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277) intestinal epithelial structure maintenance(GO:0060729)
0.0 0.2 GO:0034205 beta-amyloid formation(GO:0034205) amyloid precursor protein catabolic process(GO:0042987)
0.0 0.2 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.3 GO:0042531 tyrosine phosphorylation of STAT protein(GO:0007260) regulation of tyrosine phosphorylation of STAT protein(GO:0042509) positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.0 0.1 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 1.0 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.2 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 0.5 GO:0051014 actin filament severing(GO:0051014)
0.0 0.4 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0 0.5 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.0 GO:0002513 tolerance induction(GO:0002507) tolerance induction to self antigen(GO:0002513)
0.0 0.2 GO:1904356 regulation of telomere maintenance via telomere lengthening(GO:1904356)
0.0 0.5 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.0 0.3 GO:0006958 humoral immune response mediated by circulating immunoglobulin(GO:0002455) complement activation, classical pathway(GO:0006958)
0.0 0.1 GO:0051673 membrane disruption in other organism(GO:0051673)
0.0 0.2 GO:0032418 lysosome localization(GO:0032418)
0.0 0.5 GO:0006505 GPI anchor metabolic process(GO:0006505)
0.0 0.1 GO:0045719 negative regulation of peptidyl-serine phosphorylation(GO:0033137) negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.4 GO:0003094 glomerular filtration(GO:0003094)
0.0 2.7 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.1 GO:1902047 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.0 0.1 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.9 GO:0036503 ERAD pathway(GO:0036503)
0.0 0.3 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.0 0.4 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.2 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.2 GO:0043114 regulation of vascular permeability(GO:0043114)
0.0 0.6 GO:0042113 B cell activation(GO:0042113)
0.0 0.3 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.1 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.0 0.3 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.1 GO:0090148 membrane fission(GO:0090148)
0.0 0.2 GO:0009311 oligosaccharide metabolic process(GO:0009311)
0.0 0.8 GO:0006119 oxidative phosphorylation(GO:0006119)
0.0 0.3 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 0.2 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173) inositol phosphate-mediated signaling(GO:0048016)
0.0 1.3 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.4 GO:0016575 histone deacetylation(GO:0016575)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.2 0.9 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.2 0.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.2 2.0 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.2 1.0 GO:1990923 PET complex(GO:1990923)
0.2 1.0 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.2 1.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.2 2.0 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 0.3 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.1 0.6 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.3 GO:0043614 multi-eIF complex(GO:0043614)
0.1 0.5 GO:0071203 WASH complex(GO:0071203)
0.1 0.7 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 0.6 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 0.4 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.1 0.3 GO:0098842 postsynaptic early endosome(GO:0098842)
0.1 0.5 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 0.5 GO:0070876 SOSS complex(GO:0070876)
0.1 0.2 GO:0097361 CIA complex(GO:0097361)
0.1 0.6 GO:0031526 brush border membrane(GO:0031526)
0.1 0.6 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 0.4 GO:0070062 extracellular exosome(GO:0070062)
0.1 0.9 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 0.5 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 1.2 GO:0005685 U1 snRNP(GO:0005685)
0.1 0.5 GO:0005688 U6 snRNP(GO:0005688)
0.1 1.9 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.4 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.6 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.5 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.4 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.3 GO:0070847 core mediator complex(GO:0070847)
0.0 0.8 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.2 GO:0043291 RAVE complex(GO:0043291)
0.0 0.7 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.2 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.7 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.4 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.3 GO:0070652 HAUS complex(GO:0070652)
0.0 0.3 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.7 GO:0045180 basal cortex(GO:0045180)
0.0 0.6 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.3 GO:0045171 intercellular bridge(GO:0045171)
0.0 1.1 GO:0016605 PML body(GO:0016605)
0.0 0.5 GO:0015030 Cajal body(GO:0015030)
0.0 0.2 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.7 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.4 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.4 GO:0070187 telosome(GO:0070187)
0.0 0.6 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.5 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.3 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.5 GO:0032039 integrator complex(GO:0032039)
0.0 0.2 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.7 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.4 GO:0097546 ciliary base(GO:0097546)
0.0 1.7 GO:0005871 kinesin complex(GO:0005871)
0.0 5.7 GO:0005764 lysosome(GO:0005764)
0.0 0.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 1.7 GO:0031201 SNARE complex(GO:0031201)
0.0 0.1 GO:0000938 GARP complex(GO:0000938)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 0.3 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.9 GO:0099634 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 0.1 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 1.5 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.1 GO:0005903 brush border(GO:0005903)
0.0 0.3 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.7 GO:0016342 catenin complex(GO:0016342)
0.0 0.6 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)
0.0 0.5 GO:0016529 sarcoplasm(GO:0016528) sarcoplasmic reticulum(GO:0016529)
0.0 1.4 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.1 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.1 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.4 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.1 GO:0035060 brahma complex(GO:0035060)
0.0 0.6 GO:0000777 condensed chromosome kinetochore(GO:0000777)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.2 1.5 GO:0004997 thyrotropin-releasing hormone receptor activity(GO:0004997)
0.2 0.6 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.2 0.6 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.2 1.0 GO:0022889 serine transmembrane transporter activity(GO:0022889)
0.2 1.4 GO:0001130 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.2 1.3 GO:0030619 U1 snRNA binding(GO:0030619)
0.2 0.5 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.2 0.6 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.2 0.5 GO:0032184 SUMO polymer binding(GO:0032184)
0.2 0.3 GO:0032183 SUMO binding(GO:0032183)
0.1 0.6 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.1 0.7 GO:0043295 glutathione binding(GO:0043295)
0.1 1.2 GO:0008494 translation activator activity(GO:0008494)
0.1 0.5 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 1.0 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 1.0 GO:0034584 piRNA binding(GO:0034584)
0.1 0.4 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1 0.4 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761) N-acylmannosamine kinase activity(GO:0009384)
0.1 1.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 1.9 GO:0032190 acrosin binding(GO:0032190)
0.1 0.5 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 1.3 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.4 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 0.3 GO:0004557 alpha-galactosidase activity(GO:0004557)
0.1 0.7 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 1.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 1.9 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 1.5 GO:0051117 ATPase binding(GO:0051117)
0.1 0.7 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.1 0.6 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.5 GO:0004408 holocytochrome-c synthase activity(GO:0004408)
0.1 0.4 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.1 0.6 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 0.3 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.3 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 0.9 GO:0008172 S-methyltransferase activity(GO:0008172)
0.1 2.1 GO:0031267 small GTPase binding(GO:0031267)
0.1 0.4 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 0.4 GO:0008432 JUN kinase binding(GO:0008432)
0.1 1.1 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.1 0.4 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 0.3 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 0.6 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.1 0.3 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.1 0.5 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 0.4 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 0.8 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 0.8 GO:0004568 chitinase activity(GO:0004568)
0.1 1.4 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.3 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 0.5 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.1 0.3 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.1 0.5 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.8 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 1.6 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.1 0.6 GO:0052813 phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 0.8 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 0.6 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.1 0.3 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 0.8 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.1 1.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 0.6 GO:0005537 mannose binding(GO:0005537)
0.1 0.6 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.4 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.9 GO:0090079 translation regulator activity, nucleic acid binding(GO:0090079)
0.1 0.5 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.3 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.1 GO:0042806 fucose binding(GO:0042806)
0.0 1.1 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.0 0.5 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.8 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.5 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.7 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.5 GO:0045503 dynein light chain binding(GO:0045503)
0.0 1.0 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.3 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.6 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.6 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.6 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.3 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.3 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.3 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.2 GO:0015131 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.0 0.8 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.3 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.1 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.2 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.7 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.4 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.1 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086)
0.0 0.7 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 2.0 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.8 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.3 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.3 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.6 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.4 GO:0002039 p53 binding(GO:0002039)
0.0 0.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.4 GO:0031386 protein tag(GO:0031386)
0.0 0.4 GO:0017069 snRNA binding(GO:0017069)
0.0 0.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 1.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 1.0 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.3 GO:0005163 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.0 0.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.0 0.6 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.3 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.3 GO:0070740 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.1 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.3 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.0 0.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.1 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.5 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.5 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 0.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0005351 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 1.3 GO:0019902 phosphatase binding(GO:0019902)
0.0 0.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 1.2 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.8 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 1.7 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 1.1 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 1.7 GO:1901981 phosphatidylinositol phosphate binding(GO:1901981)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 1.8 GO:0101005 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.5 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887) DNA polymerase activity(GO:0034061)
0.0 1.0 GO:0008276 protein methyltransferase activity(GO:0008276)
0.0 0.3 GO:0016411 acylglycerol O-acyltransferase activity(GO:0016411)
0.0 0.1 GO:0008743 L-threonine 3-dehydrogenase activity(GO:0008743)
0.0 4.5 GO:0030695 GTPase regulator activity(GO:0030695)
0.0 1.7 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.1 GO:0034595 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
0.0 0.1 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003) ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0 2.5 GO:0030246 carbohydrate binding(GO:0030246)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 1.1 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 0.6 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 1.0 PID S1P S1P2 PATHWAY S1P2 pathway
0.1 0.2 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 1.1 PID ARF 3PATHWAY Arf1 pathway
0.1 0.4 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 0.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 0.6 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 0.8 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.1 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.4 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.5 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.9 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.6 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.6 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.7 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.9 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.7 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.8 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.3 PID P73PATHWAY p73 transcription factor network
0.0 0.6 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.5 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.6 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.3 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.7 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.7 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.3 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.1 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.3 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.9 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.2 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.3 PID AURORA B PATHWAY Aurora B signaling
0.0 0.5 ST FAS SIGNALING PATHWAY Fas Signaling Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.2 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 1.0 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 0.3 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.1 0.8 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.1 0.9 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 0.6 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 1.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 0.9 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 1.2 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 0.6 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 1.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 0.8 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 1.0 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 0.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.5 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 2.1 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.4 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.6 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.5 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.6 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.8 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.9 REACTOME KINESINS Genes involved in Kinesins
0.0 0.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.8 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.2 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.6 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.3 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.2 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.4 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.8 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.4 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.5 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.0 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.3 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.6 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.5 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.8 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.4 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.3 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.3 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 1.1 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.9 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.4 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.6 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.5 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.1 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.4 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 1.0 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.8 REACTOME DNA REPAIR Genes involved in DNA Repair
0.0 1.5 REACTOME TRANSCRIPTION Genes involved in Transcription
0.0 0.3 REACTOME PI3K EVENTS IN ERBB4 SIGNALING Genes involved in PI3K events in ERBB4 signaling
0.0 0.1 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin