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PRJNA195909:zebrafish embryo and larva development

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Results for sp8a+sp8b_sp4_rsl1d1+sp3a_klf4

Z-value: 0.40

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Transcription factors associated with sp8a+sp8b_sp4_rsl1d1+sp3a_klf4

Gene Symbol Gene ID Gene Info
ENSDARG00000011870 sp8 transcription factor a
ENSDARG00000056666 sp8 transcription factor b
ENSDARG00000005186 sp4 transcription factor
ENSDARG00000001549 sp3a transcription factor
ENSDARG00000005846 Sp5 transcription factor b
ENSDARG00000079922 Kruppel-like factor 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sp3adr11_v1_chr9_+_2762270_27624150.826.8e-03Click!
sp8bdr11_v1_chr16_+_19536614_19536761-0.771.5e-02Click!
sp8adr11_v1_chr19_-_2317558_2317558-0.722.9e-02Click!
sp4dr11_v1_chr19_+_2364552_23645520.674.6e-02Click!
FO704755.1dr11_v1_chr6_+_3809346_38093460.511.6e-01Click!
klf4dr11_v1_chr21_-_435466_435466-0.049.1e-01Click!

Activity profile of sp8a+sp8b_sp4_rsl1d1+sp3a_klf4 motif

Sorted Z-values of sp8a+sp8b_sp4_rsl1d1+sp3a_klf4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_1625080 0.72 ENSDART00000137285
nucleoporin 155
chr12_+_46634736 0.67 ENSDART00000008009
tripartite motif containing 16
chr22_+_835728 0.65 ENSDART00000003325
DENN/MADD domain containing 2Db
chr10_-_34002185 0.59 ENSDART00000046599
zygote arrest 1-like
chr8_-_410728 0.55 ENSDART00000151255
tripartite motif containing 36
chr3_+_1211242 0.51 ENSDART00000171287
ENSDART00000165769
polymerase (DNA-directed), delta interacting protein 3
chr23_-_18707418 0.47 ENSDART00000144668
ENSDART00000141205
ENSDART00000016765
zgc:103759
chr5_+_66132394 0.47 ENSDART00000073892
zgc:114041
chr24_-_20599781 0.46 ENSDART00000179664
ENSDART00000141823
zinc finger and BTB domain containing 47b
chr2_+_35880600 0.45 ENSDART00000004277
laminin, gamma 1
chr7_+_1473929 0.45 ENSDART00000050687
lysophosphatidylcholine acyltransferase 4
chr3_-_21118969 0.43 ENSDART00000129016
MYC-associated zinc finger protein a (purine-binding transcription factor)
chr22_-_16275236 0.42 ENSDART00000149051
cell division cycle 14Ab
chr16_+_43077909 0.40 ENSDART00000014140
RUN domain containing 3b
chr20_-_182841 0.39 ENSDART00000064546
si:ch211-241j12.3
chr3_-_40054615 0.38 ENSDART00000003511
ENSDART00000102540
ENSDART00000146121
lethal giant larvae homolog 1 (Drosophila)
chr19_+_26340736 0.38 ENSDART00000013497
myosin regulatory light chain interacting protein a
chr9_+_8380728 0.36 ENSDART00000133501
si:ch1073-75o15.4
chr7_+_67325933 0.35 ENSDART00000170575
ENSDART00000183342
nuclear factor of activated T cells 5b
chr19_-_6193448 0.35 ENSDART00000151405
Ets2 repressor factor
chr1_-_34450622 0.34 ENSDART00000083736
LIM domain 7b
chr7_+_10563017 0.34 ENSDART00000193520
ENSDART00000173125
zinc finger, AN1-type domain 6
chr12_+_48340133 0.34 ENSDART00000152899
ENSDART00000153335
ENSDART00000054788
DNA-damage-inducible transcript 4
chr8_-_4100365 0.34 ENSDART00000142846
cut-like homeobox 2b
chr16_+_53455638 0.33 ENSDART00000045792
ENSDART00000154189
RNA binding motif protein 24b
chr1_+_57371447 0.33 ENSDART00000152229
ENSDART00000181077
si:dkey-27j5.3
chr2_+_25657958 0.33 ENSDART00000161407
TRAF2 and NCK interacting kinase a
chr5_-_68782641 0.33 ENSDART00000141699
methylphosphate capping enzyme
chr1_-_34450784 0.33 ENSDART00000140515
LIM domain 7b
chr2_+_25658112 0.33 ENSDART00000051234
TRAF2 and NCK interacting kinase a
chr22_-_6562618 0.32 ENSDART00000106100
zgc:171490
chr16_-_7793457 0.32 ENSDART00000113483
tripartite motif containing 71, E3 ubiquitin protein ligase
chr1_+_24469313 0.32 ENSDART00000176581
family with sequence similarity 160, member A1a
chr15_+_29025090 0.32 ENSDART00000131755
si:ch211-137a8.2
chr8_-_410199 0.31 ENSDART00000091177
ENSDART00000122979
ENSDART00000151331
ENSDART00000151155
tripartite motif containing 36
chr23_+_35426404 0.31 ENSDART00000164658
si:ch211-225h24.2
chr25_+_35375848 0.31 ENSDART00000155721
anoctamin 3
chr10_+_16501699 0.31 ENSDART00000121864
solute carrier family 27 (fatty acid transporter), member 6
chr2_+_58221163 0.31 ENSDART00000157939

chr19_-_6193067 0.31 ENSDART00000092656
ENSDART00000140347
Ets2 repressor factor
chr5_-_69482891 0.31 ENSDART00000109487

chr23_+_45822935 0.31 ENSDART00000161892
vitamin D receptor a
chr17_-_25831569 0.30 ENSDART00000148743
hedgehog acyltransferase
chr15_+_29024895 0.30 ENSDART00000141164
ENSDART00000144126
si:ch211-137a8.2
chr19_+_46113828 0.30 ENSDART00000159331
ENSDART00000161826
RNA binding motif protein 24a
chr18_-_127558 0.30 ENSDART00000149556
transient receptor potential cation channel, subfamily M, member 7
chr22_-_20924564 0.30 ENSDART00000100642
ENSDART00000032770
elongation factor RNA polymerase II
chr17_-_18898115 0.30 ENSDART00000028044
galactosylceramidase b
chr21_+_34167178 0.29 ENSDART00000158308
transient receptor potential cation channel, subfamily C, member 5b
chr8_+_8166285 0.29 ENSDART00000147940
plexin B3
chr6_+_41503854 0.29 ENSDART00000136538
ENSDART00000140108
ENSDART00000084861
cytokine inducible SH2-containing protein
chr20_+_4157815 0.29 ENSDART00000113132
glyceronephosphate O-acyltransferase
chr3_+_49074008 0.29 ENSDART00000168864
zgc:112146
chr22_-_20924747 0.28 ENSDART00000185845
ENSDART00000179672
elongation factor RNA polymerase II
chr6_-_25165693 0.28 ENSDART00000167259
zinc finger protein 326
chr21_-_5056812 0.28 ENSDART00000139713
ENSDART00000140859
zgc:77838
chr11_-_34577034 0.28 ENSDART00000133302
ENSDART00000184367
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4a
chr2_-_48826707 0.28 ENSDART00000134711
supervillin b
chr7_-_19332293 0.28 ENSDART00000169668
ENSDART00000137575
ENSDART00000090406
dedicator of cytokinesis 11
chr21_-_43398122 0.28 ENSDART00000050533
cyclin I family, member 2
chr23_+_553396 0.27 ENSDART00000034707
LSM family member 14B
chr21_-_11646878 0.27 ENSDART00000162426
ENSDART00000135937
ENSDART00000131448
ENSDART00000148097
ENSDART00000133443
calpastatin
chr7_+_38349667 0.27 ENSDART00000010046
rhophilin, Rho GTPase binding protein 2
chr15_-_1001177 0.27 ENSDART00000160730
zgc:162936
chr22_+_1006573 0.27 ENSDART00000123458
peroxisome proliferator-activated receptor delta a
chr5_+_68807170 0.27 ENSDART00000017849
hairy and enhancer of split related-7
chr22_+_24623936 0.27 ENSDART00000160924
mucolipin 2
chr9_-_11263228 0.27 ENSDART00000113847
chondroitin polymerizing factor a
chr20_+_46741074 0.26 ENSDART00000145294
si:ch211-57i17.1
chr1_+_7189856 0.26 ENSDART00000092114
si:ch73-383l1.1
chr23_+_12160900 0.26 ENSDART00000136046
protein phosphatase 1, regulatory subunit 3Da
chr8_-_53044300 0.26 ENSDART00000191653
nuclear receptor subfamily 6, group A, member 1a
chr10_-_32851847 0.26 ENSDART00000134255
tripartite motif containing 37
chr5_-_23696926 0.26 ENSDART00000021462
ring finger protein 128a
chr24_+_17005647 0.26 ENSDART00000149149
zinc finger protein, X-linked
chr24_-_11076400 0.26 ENSDART00000003195
charged multivesicular body protein 4C
chr10_-_26202766 0.26 ENSDART00000136393
FH2 domain containing 3
chr19_-_867071 0.25 ENSDART00000122257
eomesodermin homolog a
chr1_-_54107321 0.25 ENSDART00000148382
ENSDART00000150357
regulatory factor X, 1b (influences HLA class II expression)
chr23_-_41762956 0.25 ENSDART00000128302
serine/threonine kinase 35
chr7_+_55518519 0.25 ENSDART00000098476
ENSDART00000149915
chromatin licensing and DNA replication factor 1
chr3_+_36972586 0.25 ENSDART00000102784
si:ch211-18i17.2
chr20_+_812012 0.25 ENSDART00000179299
ENSDART00000137135
meiosis-specific, MEI4 homolog (S. cerevisiae)
chr17_+_25856671 0.24 ENSDART00000064817
WAPL cohesin release factor a
chr9_-_10145795 0.24 ENSDART00000004745
ENSDART00000143295
histamine N-methyltransferase
chr7_-_24520866 0.24 ENSDART00000077039
fatty acid amide hydrolase 2b
chr10_+_39199547 0.24 ENSDART00000075943
etoposide induced 2.4
chr2_+_59015878 0.24 ENSDART00000148816
ENSDART00000122795
si:ch1073-391i24.1
chr21_-_32060993 0.24 ENSDART00000131651
si:ch211-160j14.2
chr10_-_41352502 0.24 ENSDART00000052971
ENSDART00000128156
RAB11 family interacting protein 1 (class I) b
chr21_-_43398457 0.24 ENSDART00000166530
cyclin I family, member 2
chr20_+_16173618 0.24 ENSDART00000192109
ENSDART00000104112
ENSDART00000129633
zyg-11 homolog (C. elegans)
chr24_-_28333029 0.24 ENSDART00000149015
ENSDART00000129174
protein kinase, AMP-activated, gamma 2 non-catalytic subunit a
chr3_+_29469283 0.24 ENSDART00000103592
family with sequence similarity 83, member Fa
chr23_-_41762797 0.23 ENSDART00000186564
serine/threonine kinase 35
chr24_-_38644937 0.23 ENSDART00000170194
solute carrier family 6, member 16b
chr10_+_31809226 0.23 ENSDART00000087898
forkhead box O1 b
chr8_+_2656231 0.23 ENSDART00000160833
family with sequence similarity 102, member Aa
chr20_-_51656512 0.23 ENSDART00000129965

chr3_+_32410746 0.23 ENSDART00000025496
RAS related
chr22_-_10539180 0.23 ENSDART00000131217
inositol 1,3,4,5,6-pentakisphosphate 2-kinase
chr20_-_52928541 0.23 ENSDART00000162812
farnesyl-diphosphate farnesyltransferase 1
chr9_+_55536005 0.23 ENSDART00000192364
matrix-remodelling associated 5b
chr17_-_53329704 0.23 ENSDART00000193895
exonuclease 3'-5' domain containing 1
chr21_-_39670375 0.22 ENSDART00000151567
uncharacterized serine/threonine-protein kinase SgK494b
chr1_+_45707219 0.22 ENSDART00000143363
si:ch211-214c7.4
chr18_-_127873 0.22 ENSDART00000148490
transient receptor potential cation channel, subfamily M, member 7
chr24_-_36593876 0.22 ENSDART00000160901

chr20_-_54564018 0.22 ENSDART00000099832
zgc:153012
chr24_-_41180149 0.22 ENSDART00000019975
activin A receptor type 2Ba
chr14_+_1127866 0.21 ENSDART00000172820
SEC24 homolog B, COPII coat complex component
chr2_-_39675829 0.21 ENSDART00000147821
splA/ryanodine receptor domain and SOCS box containing 4a
chr16_-_29387215 0.21 ENSDART00000148787
S100 calcium binding protein A1
chr21_+_1647990 0.21 ENSDART00000148540
ferrochelatase
chr3_+_18437397 0.21 ENSDART00000136243
ENSDART00000184882
ENSDART00000135470
TBC1 domain family, member 16
chr20_+_51061695 0.21 ENSDART00000134416
im:7140055
chr18_+_27077853 0.21 ENSDART00000125326
ENSDART00000192660
ENSDART00000098334
protein phosphatase 1, regulatory subunit 15B
chr21_-_13856689 0.21 ENSDART00000102197
family with sequence similarity 129, member Ba
chr6_-_7776612 0.21 ENSDART00000190269
myosin, heavy chain 9a, non-muscle
chr3_+_46559639 0.21 ENSDART00000146189
ENSDART00000127832
ENSDART00000151035
ribonucleoprotein, PTB-binding 1
chr24_+_37449893 0.20 ENSDART00000164405
NLR family, CARD domain containing 3
chr15_-_23942861 0.20 ENSDART00000002824
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr23_-_31645760 0.20 ENSDART00000035031
serum/glucocorticoid regulated kinase 1
chr8_+_7740004 0.20 ENSDART00000170184
ENSDART00000187811
FYVE, RhoGEF and PH domain containing 1
chr20_+_42565049 0.20 ENSDART00000061101
insulin-like growth factor 2 receptor
chr5_-_13086616 0.20 ENSDART00000051664
yippee-like 1
chr20_-_16156419 0.20 ENSDART00000037420
Ral GEF with PH domain and SH3 binding motif 2
chr12_-_37449396 0.20 ENSDART00000152951
CDC42 effector protein (Rho GTPase binding) 4b
chr19_-_10295173 0.20 ENSDART00000136697
CCR4-NOT transcription complex, subunit 3b
chr21_+_3941758 0.19 ENSDART00000181345
senataxin
chr16_-_1757521 0.19 ENSDART00000124660
activating signal cointegrator 1 complex subunit 3
chr5_-_64431927 0.19 ENSDART00000158248
bromodomain containing 3b
chr16_-_21489514 0.19 ENSDART00000149525
ENSDART00000148517
ENSDART00000146914
ENSDART00000186493
ENSDART00000193081
ENSDART00000186017
membrane protein, palmitoylated 6a (MAGUK p55 subfamily member 6)
chr22_-_38459316 0.19 ENSDART00000149683
ENSDART00000098461
protein tyrosine kinase 7a
chr10_-_244745 0.19 ENSDART00000136551
kelch-like family member 35
chr7_+_38962207 0.19 ENSDART00000173565
diacylglycerol kinase, zeta a
chr11_+_6881001 0.19 ENSDART00000170331
kelch-like family member 26
chr13_-_35908275 0.19 ENSDART00000013961
MYCL proto-oncogene, bHLH transcription factor a
chr24_+_42132962 0.19 ENSDART00000187739
WW domain containing E3 ubiquitin protein ligase 1
chr25_-_348784 0.19 ENSDART00000059514
prickle homolog 1a
chr14_-_237130 0.19 ENSDART00000164988
biorientation of chromosomes in cell division 1-like 1
chr21_-_41369539 0.19 ENSDART00000187546
cytoplasmic polyadenylation element binding protein 4b
chr2_+_43894368 0.19 ENSDART00000143885
guanylate binding protein 3
chr2_-_32513538 0.19 ENSDART00000056640
ATP-binding cassette, sub-family F (GCN20), member 2a
chr22_+_24559947 0.19 ENSDART00000169847
WD repeat domain 47b
chr23_-_45398622 0.18 ENSDART00000053571
ENSDART00000149464
zgc:100911
chr7_+_69528850 0.18 ENSDART00000109507
Rap1 GTPase-GDP dissociation stimulator 1
chr9_-_34269066 0.18 ENSDART00000059955
immunoglobulin-like domain containing receptor 1b
chr21_-_14692119 0.18 ENSDART00000123047
euchromatic histone-lysine N-methyltransferase 1b
chr19_-_35450857 0.18 ENSDART00000179357
anillin, actin binding protein
chr2_+_1988036 0.18 ENSDART00000155956
synovial sarcoma, X breakpoint 2 interacting protein a
chr8_-_51753604 0.18 ENSDART00000007090
T-box 16
chr21_+_45386033 0.18 ENSDART00000151773
jade family PHD finger 2
chr5_-_12031174 0.18 ENSDART00000159896
cytosolic arginine sensor for mTORC1 subunit 1
chr3_+_15776446 0.18 ENSDART00000146651
zinc finger protein 652
chr21_+_40685895 0.18 ENSDART00000017709
coiled-coil domain containing 82
chr21_-_30293224 0.18 ENSDART00000101051
stem-loop binding protein 2
chr4_-_77563411 0.18 ENSDART00000186841

chr4_-_16124417 0.18 ENSDART00000128079
ENSDART00000077664
ATPase plasma membrane Ca2+ transporting 1a
chr14_+_30291611 0.18 ENSDART00000173004
microtubule associated tumor suppressor 1a
chr8_+_25733872 0.18 ENSDART00000156340
si:ch211-167b20.8
chr13_+_42309688 0.18 ENSDART00000158367
insulin-degrading enzyme
chr18_+_6558146 0.18 ENSDART00000169401
beta-1,4-N-acetyl-galactosaminyl transferase 3b
chr4_-_17353100 0.18 ENSDART00000134467
ENSDART00000189019
PARP1 binding protein
chr8_+_47219107 0.17 ENSDART00000146018
ENSDART00000075068
methylenetetrahydrofolate reductase (NAD(P)H)
chr9_+_4378153 0.17 ENSDART00000191264
ENSDART00000182384
kalirin RhoGEF kinase a
chr19_-_20403507 0.17 ENSDART00000052603
ENSDART00000137590
deleted in azoospermia-like
chr2_+_38924975 0.17 ENSDART00000109219
RAS (RAD and GEM)-like GTP binding 2
chr14_-_24110707 0.17 ENSDART00000133522
ENSDART00000123152
cytoplasmic polyadenylation element binding protein 4a
chr18_+_26895994 0.17 ENSDART00000098347
cholesterol 25-hydroxylase like 1, tandem duplicate 2
chr23_-_10745288 0.17 ENSDART00000140745
ENSDART00000013768
eukaryotic translation initiation factor 4E family member 3
chr2_-_7800702 0.17 ENSDART00000146360
transducin (beta)-like 1 X-linked receptor 1b
chr1_-_59232267 0.17 ENSDART00000169658
ENSDART00000163257
A kinase (PRKA) anchor protein 8-like
chr9_+_3035128 0.17 ENSDART00000140693
si:ch211-173m16.2
chr3_-_15131438 0.17 ENSDART00000131720
exportin 6
chr8_+_23165749 0.17 ENSDART00000063057
DnaJ (Hsp40) homolog, subfamily C, member 5aa
chr23_+_2825940 0.17 ENSDART00000135781
phospholipase C, gamma 1
chr3_+_24595922 0.17 ENSDART00000169405
si:dkey-68o6.5
chr7_+_24520518 0.17 ENSDART00000173604
bloodthirsty-related gene family, member 9
chr9_+_22375779 0.17 ENSDART00000183956
diacylglycerol kinase, gamma
chr10_-_2942900 0.17 ENSDART00000002622
occludin a
chr20_-_14781904 0.17 ENSDART00000187200
ENSDART00000179912
ENSDART00000160481
ENSDART00000026969
SUN domain containing ossification factor
chr23_+_30730121 0.17 ENSDART00000134141
additional sex combs like transcriptional regulator 1
chr19_-_26769867 0.17 ENSDART00000043776
ENSDART00000159489
ENSDART00000138675
proline-rich coiled-coil 2A
chr24_-_20208474 0.16 ENSDART00000139329
cryptochrome DASH
chr21_+_21279159 0.16 ENSDART00000148346
inositol-trisphosphate 3-kinase Ca
chr6_+_3334392 0.16 ENSDART00000133707
ENSDART00000130879
ST3 beta-galactoside alpha-2,3-sialyltransferase 3a
chr8_+_53051701 0.16 ENSDART00000131514
NAD kinase a
chr10_-_35248502 0.16 ENSDART00000087477
SMG8 nonsense mediated mRNA decay factor
chr15_+_47418565 0.16 ENSDART00000155709
ClpB homolog, mitochondrial AAA ATPase chaperonin
chr13_+_47821524 0.16 ENSDART00000109978
zinc finger CCCH-type containing 6
chr15_-_19128705 0.16 ENSDART00000152428
Rho GTPase activating protein 32a
chr13_-_42673978 0.16 ENSDART00000133848
ENSDART00000099738
ENSDART00000099729
ENSDART00000169083
leucine rich repeat (in FLII) interacting protein 2
chr13_+_33688474 0.16 ENSDART00000161465

chr13_+_49727333 0.16 ENSDART00000168799
ENSDART00000037559
geranylgeranyl diphosphate synthase 1
chr19_-_46088429 0.16 ENSDART00000161385
phosphatidylserine synthase 1b
chr8_-_22288004 0.16 ENSDART00000100042
si:ch211-147a11.3
chr15_+_29393519 0.16 ENSDART00000193488
ENSDART00000112375
glycerophosphodiester phosphodiesterase domain containing 5b
chr15_+_28410664 0.16 ENSDART00000132028
ENSDART00000057697
ENSDART00000057257
phosphatidylinositol transfer protein, alpha a
chr16_-_8120203 0.16 ENSDART00000193430
SNF related kinase a

Network of associatons between targets according to the STRING database.

First level regulatory network of sp8a+sp8b_sp4_rsl1d1+sp3a_klf4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228) protein localization to nuclear envelope(GO:0090435)
0.2 0.5 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.2 0.6 GO:0003228 atrial cardiac muscle tissue development(GO:0003228)
0.1 0.3 GO:1904869 positive regulation of protein localization to nucleus(GO:1900182) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.1 0.6 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.1 0.3 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
0.1 0.4 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.1 0.3 GO:0019284 L-methionine biosynthetic process from S-adenosylmethionine(GO:0019284)
0.1 0.3 GO:0060571 invagination involved in gastrulation with mouth forming second(GO:0055109) morphogenesis of an epithelial fold(GO:0060571)
0.1 0.2 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.1 0.2 GO:0001692 histamine metabolic process(GO:0001692)
0.1 0.3 GO:0008356 asymmetric cell division(GO:0008356)
0.1 0.3 GO:0060967 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.1 0.3 GO:0010586 miRNA metabolic process(GO:0010586)
0.1 0.2 GO:0007008 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.1 0.2 GO:0048340 paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341) intermediate mesoderm development(GO:0048389)
0.1 0.2 GO:0033301 cell cycle comprising mitosis without cytokinesis(GO:0033301)
0.1 0.3 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.1 0.2 GO:0052746 inositol phosphorylation(GO:0052746)
0.1 0.2 GO:0035477 regulation of angioblast cell migration involved in selective angioblast sprouting(GO:0035477)
0.1 0.2 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.1 0.1 GO:0007220 Notch receptor processing(GO:0007220)
0.1 0.4 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.1 0.4 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.6 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:1990868 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869) negative regulation of lymphocyte migration(GO:2000402) negative regulation of T cell migration(GO:2000405)
0.0 0.3 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.5 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.1 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.0 0.5 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.5 GO:0016074 snoRNA metabolic process(GO:0016074)
0.0 0.2 GO:0072104 renal system vasculature morphogenesis(GO:0061438) kidney vasculature morphogenesis(GO:0061439) glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.0 0.4 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0 0.0 GO:1905067 negative regulation of canonical Wnt signaling pathway involved in heart development(GO:1905067)
0.0 0.1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.1 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.0 0.3 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.3 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.2 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.2 GO:0016115 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0 0.2 GO:0034505 tooth mineralization(GO:0034505)
0.0 0.2 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.0 0.3 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.0 0.3 GO:0051673 membrane disruption in other organism(GO:0051673)
0.0 0.3 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.0 0.2 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.2 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.1 GO:0010898 regulation of triglyceride catabolic process(GO:0010896) positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.1 GO:0048313 organelle inheritance(GO:0048308) Golgi inheritance(GO:0048313)
0.0 0.1 GO:0034729 histone H3-K79 methylation(GO:0034729) regulation of transcription regulatory region DNA binding(GO:2000677)
0.0 0.0 GO:0070417 cellular response to cold(GO:0070417)
0.0 0.1 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.0 0.2 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.1 GO:0098773 skin epidermis development(GO:0098773)
0.0 0.1 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.2 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.2 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
0.0 0.2 GO:1900118 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.1 GO:0060231 mesenchymal to epithelial transition(GO:0060231)
0.0 0.6 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.2 GO:0032447 tRNA wobble position uridine thiolation(GO:0002143) protein urmylation(GO:0032447)
0.0 0.5 GO:0010962 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.0 0.0 GO:0007063 regulation of sister chromatid cohesion(GO:0007063) regulation of cohesin loading(GO:0071922)
0.0 0.2 GO:0090660 cerebrospinal fluid circulation(GO:0090660) regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.2 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.0 0.1 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.0 0.2 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.3 GO:0031937 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.3 GO:0021535 cell migration in hindbrain(GO:0021535)
0.0 0.1 GO:0051148 smooth muscle cell differentiation(GO:0051145) negative regulation of muscle cell differentiation(GO:0051148)
0.0 0.2 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.5 GO:0072663 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.2 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.1 GO:0055071 manganese ion homeostasis(GO:0055071)
0.0 0.1 GO:0032207 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208)
0.0 0.4 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0 0.2 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.0 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0099553 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.0 0.1 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.0 0.1 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 0.1 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0 0.1 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.0 0.1 GO:0007603 phototransduction, visible light(GO:0007603)
0.0 0.1 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.1 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.0 0.1 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.1 GO:0003272 endocardial cushion formation(GO:0003272)
0.0 0.3 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.2 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.0 GO:0010885 regulation of cholesterol storage(GO:0010885)
0.0 0.1 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.0 0.1 GO:0090234 regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
0.0 0.1 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.3 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.3 GO:0000076 DNA replication checkpoint(GO:0000076)
0.0 0.2 GO:0046850 regulation of bone remodeling(GO:0046850)
0.0 0.1 GO:0021557 oculomotor nerve development(GO:0021557)
0.0 0.2 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.0 0.1 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.0 0.2 GO:0009086 methionine biosynthetic process(GO:0009086)
0.0 0.1 GO:0003232 bulbus arteriosus development(GO:0003232)
0.0 0.0 GO:0048478 replication fork protection(GO:0048478)
0.0 0.1 GO:0045056 transcytosis(GO:0045056)
0.0 0.0 GO:0032263 guanine salvage(GO:0006178) GMP salvage(GO:0032263) guanine biosynthetic process(GO:0046099)
0.0 0.3 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.0 GO:0032049 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin biosynthetic process(GO:0032049)
0.0 0.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.1 GO:0019478 D-amino acid catabolic process(GO:0019478) D-serine catabolic process(GO:0036088) D-amino acid metabolic process(GO:0046416) D-serine metabolic process(GO:0070178)
0.0 0.4 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.1 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.2 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.0 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.0 0.0 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.2 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.0 0.0 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.0 0.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.1 GO:1902915 negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.0 0.1 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.1 GO:0060300 regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.0 0.0 GO:0035676 anterior lateral line neuromast hair cell development(GO:0035676)
0.0 0.1 GO:0071800 podosome assembly(GO:0071800)
0.0 0.2 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.2 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.1 GO:0003242 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.0 0.1 GO:1904357 negative regulation of telomere maintenance via telomerase(GO:0032211) negative regulation of telomere maintenance via telomere lengthening(GO:1904357)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0034969 histone arginine methylation(GO:0034969)
0.0 0.1 GO:2000815 regulation of mRNA stability involved in response to stress(GO:0010610) regulation of mRNA stability involved in response to oxidative stress(GO:2000815)
0.0 0.1 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.1 GO:0046620 regulation of organ growth(GO:0046620)
0.0 0.0 GO:0060959 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) Schwann cell migration(GO:0036135) cardiac neuron differentiation(GO:0060945) cardiac neuron development(GO:0060959)
0.0 0.2 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.1 GO:0006772 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.0 0.1 GO:0050655 dermatan sulfate proteoglycan metabolic process(GO:0050655)
0.0 0.2 GO:0071350 interleukin-15-mediated signaling pathway(GO:0035723) response to interleukin-15(GO:0070672) cellular response to interleukin-15(GO:0071350)
0.0 0.2 GO:0051310 metaphase plate congression(GO:0051310)
0.0 0.1 GO:0010456 cell proliferation in dorsal spinal cord(GO:0010456)
0.0 0.0 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.1 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.0 0.1 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.1 GO:0046546 development of primary male sexual characteristics(GO:0046546)
0.0 0.1 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.3 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.0 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.0 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) histone mRNA metabolic process(GO:0008334)
0.0 0.0 GO:0001782 B cell homeostasis(GO:0001782)
0.0 0.1 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.2 GO:0048922 posterior lateral line neuromast deposition(GO:0048922)
0.0 0.0 GO:0032801 receptor catabolic process(GO:0032801)
0.0 0.0 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.1 GO:0045199 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.1 GO:0021707 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.1 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.0 0.5 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 0.1 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.0 0.1 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.0 0.0 GO:0039529 RIG-I signaling pathway(GO:0039529) regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039531) regulation of RIG-I signaling pathway(GO:0039535)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.0 GO:0060334 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.0 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.4 GO:1902636 kinociliary basal body(GO:1902636)
0.1 0.3 GO:0044609 DBIRD complex(GO:0044609)
0.1 0.4 GO:0061700 GATOR2 complex(GO:0061700)
0.1 0.2 GO:0098536 deuterosome(GO:0098536)
0.0 0.2 GO:1990498 mitotic spindle microtubule(GO:1990498)
0.0 0.2 GO:1990923 PET complex(GO:1990923)
0.0 0.3 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.3 GO:0016234 inclusion body(GO:0016234)
0.0 0.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.5 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.6 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.2 GO:0005845 mRNA cap binding complex(GO:0005845)
0.0 0.1 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.0 0.1 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.2 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.0 0.2 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.2 GO:0001650 fibrillar center(GO:0001650)
0.0 0.1 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.0 0.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.2 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:1904423 dehydrodolichyl diphosphate synthase complex(GO:1904423)
0.0 0.1 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.1 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.0 0.2 GO:0098894 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.0 0.0 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.0 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0044326 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.0 0.6 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.1 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.1 GO:0030914 STAGA complex(GO:0030914)
0.0 0.0 GO:0031166 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.0 0.1 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.7 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.0 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.7 GO:0008023 transcription elongation factor complex(GO:0008023)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:1990174 phosphodiesterase decapping endonuclease activity(GO:1990174)
0.1 0.5 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 0.3 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.3 GO:1990715 mRNA CDS binding(GO:1990715)
0.1 0.3 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
0.1 0.8 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.1 0.2 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.1 0.3 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.1 0.2 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.1 0.3 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 0.2 GO:0034618 arginine binding(GO:0034618)
0.1 0.2 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 0.2 GO:0003913 DNA photolyase activity(GO:0003913)
0.1 0.4 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.3 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.2 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.9 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.1 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.0 0.5 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.2 GO:0070728 leucine binding(GO:0070728)
0.0 0.3 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.2 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.3 GO:0090079 translation regulator activity, nucleic acid binding(GO:0090079)
0.0 0.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.1 GO:0031151 histone methyltransferase activity (H3-K79 specific)(GO:0031151)
0.0 0.3 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.1 GO:0016713 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.0 0.1 GO:1902945 metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902945)
0.0 0.4 GO:2001069 glycogen binding(GO:2001069)
0.0 0.4 GO:0045159 myosin II binding(GO:0045159)
0.0 0.3 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.1 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.0 0.2 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.0 0.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.3 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.3 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.2 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.1 GO:0033592 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.0 0.1 GO:0001091 RNA polymerase II basal transcription factor binding(GO:0001091)
0.0 0.1 GO:0031701 angiotensin receptor binding(GO:0031701)
0.0 0.1 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.0 0.1 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 0.1 GO:0017020 myosin phosphatase regulator activity(GO:0017020)
0.0 0.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.1 GO:0022889 serine transmembrane transporter activity(GO:0022889)
0.0 0.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.0 GO:0004422 hypoxanthine phosphoribosyltransferase activity(GO:0004422)
0.0 0.1 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.1 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.4 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.0 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.0 0.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.0 GO:0003978 UDP-glucose 4-epimerase activity(GO:0003978)
0.0 0.1 GO:1990518 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.0 0.1 GO:0015369 calcium:proton antiporter activity(GO:0015369) metal ion:proton antiporter activity(GO:0051139)
0.0 0.2 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.3 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.1 GO:0004096 catalase activity(GO:0004096)
0.0 0.1 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.1 GO:0016433 rRNA (adenine) methyltransferase activity(GO:0016433)
0.0 0.4 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.0 GO:0004061 arylformamidase activity(GO:0004061)
0.0 0.0 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.0 0.0 GO:0043621 protein self-association(GO:0043621)
0.0 0.2 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.0 0.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.3 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.0 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.2 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.1 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.3 GO:0016208 AMP binding(GO:0016208)
0.0 0.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.1 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.2 GO:0002039 p53 binding(GO:0002039)
0.0 0.1 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.1 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.1 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.7 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.6 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 1.0 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.5 PID ATM PATHWAY ATM pathway
0.0 0.3 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.3 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.1 PID IL3 PATHWAY IL3-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.7 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.5 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.7 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.1 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.1 REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B Genes involved in APC/C:Cdc20 mediated degradation of Cyclin B
0.0 0.1 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.3 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.0 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.3 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.1 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.2 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.1 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.1 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.2 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.6 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.2 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.1 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.2 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs